• open field test | |
Locomotor, exploratory, and anxiety-related behavior. 20 min test, some at 5 min intervals. |
• ABR test | |
Auditory brainstem response. |
• hole board test | |
Exploratory behavior. |
• acoustic startle test | |
Acoustic startle response, prepulse inhibition. |
• light-dark box | |
Anxiety, avoidance behavior. 20 min test. |
• ECG | |
Heart rate and wave intervals. Conscious. |
• tail suspension test | |
Latency to immobility, duration of immobility. |
• rotarod | |
Latency to fall from accelerating rotarod. 5 trials. |
• grip strength | |
3 trials. |
• DXA | |
Body mass, fat mass, lean mass, bone mineral density and content, bone area. |
• urinalysis | |
Microalbumin, creatinine, ratio. |
• organ weights | |
Heart weight. Raw and normalized to body weight. |
• metabolic panel | |
Clinical blood chemistry (plasma). No fast. |
• lipid profile | |
Cholesterol, HDL, triglycerides, fatty acids. No fast, plasma. |
• hormone quantification | |
Insulin (plasma). |
• complete blood count | |
Hematology. |