Project measure / variable:   JaxCC1   QTc_dispersion

ID, description, units MPD:89124   QTc_dispersion   QTc dispersion, calculated as rate-corrected QT dispersion   [ms]  
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 10-12wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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JaxCC1 - QTc dispersion, calculated as rate-corrected QT dispersion



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means28.902   ms 31.889   ms
Median of the strain means26.774   ms 30.5   ms
SD of the strain means± 6.0656 ± 5.9855
Coefficient of variation (CV)0.2099 0.1877
Min–max range of strain means20.14   –   42.62   ms 23.65   –   43.65   ms
Mean sample size per strain6.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 445.0547 445.0547 3.3678 0.068
strain 16 3384.6561 211.541 1.6008 0.071
sex:strain 16 3673.2775 229.5798 1.7373 0.0423
Residuals 201 26561.8213 132.1484


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 23.662 5.1247   8 1.8119 0.2166 17.0, 32.2 -0.86
CC002/UncJ m 33.7 14.2   7 5.3669 0.4214 25.3, 64.6 0.3
CC003/UncJ f 41.06 21.92   5 9.8028 0.5338 22.9, 71.2 2.0
CC003/UncJ m 28.85 6.0539   4 3.027 0.2098 21.2, 34.8 -0.51
CC004/TauUncJ f 25.46 6.1606   5 2.7551 0.242 15.0, 29.7 -0.57
CC004/TauUncJ m 39.6 17.83   8 6.3039 0.4503 22.5, 66.3 1.29
CC006/TauUncJ f 27.725 2.25   4 1.125 0.0812 25.9, 31.0 -0.19
CC006/TauUncJ m 27.687 13.928   8 4.9244 0.5031 15.7, 58.6 -0.7
CC009/UncJ f 26.737 3.3903   8 1.1987 0.1268 22.6, 31.4 -0.36
CC009/UncJ m 24.363 3.1901   8 1.1279 0.1309 19.1, 29.0 -1.26
CC010/GeniUncJ f 27.06 4.6635   5 2.0856 0.1723 22.3, 34.5 -0.3
CC013/GeniUncJ f 24.75 2.3189   8 0.81984 0.0937 21.0, 27.4 -0.68
CC013/GeniUncJ m 41.667 21.293   3 12.293 0.511 28.0, 66.2 1.63
CC017/UncJ f 42.62 17.812   5 7.9658 0.4179 28.9, 65.7 2.26
CC017/UncJ m 43.65 18.15   4 9.0751 0.4158 27.7, 68.7 1.96
CC018/UncJ f 23.757 3.0402   7 1.1491 0.128 19.5, 28.5 -0.85
CC018/UncJ m 31.35 15.968   8 5.6455 0.5093 20.3, 70.1 -0.09
CC019/TauUncJ f 29.462 9.6302   8 3.4048 0.3269 18.7, 51.6 0.09
CC019/TauUncJ m 29.662 13.2   8 4.6668 0.445 23.0, 62.1 -0.37
CC024/GeniUncJ f 26.271 4.5726   7 1.7283 0.1741 20.4, 34.4 -0.43
CC024/GeniUncJ m 30.5 4.5141   8 1.596 0.148 23.6, 35.1 -0.23
CC025/GeniUncJ f 20.14 6.1598   5 2.7547 0.3058 10.9, 26.5 -1.44
CC025/GeniUncJ m 38.67 23.625   10 7.4709 0.6109 20.2, 97.8 1.13
CC026/GeniUncJ f 26.529 4.2574   7 1.6092 0.1605 20.8, 34.1 -0.39
CC026/GeniUncJ m 35.05 13.792   8 4.8763 0.3935 23.9, 67.2 0.53
CC032/GeniUncJ f 31.1 17.116   7 6.4694 0.5504 19.4, 69.2 0.36
CC032/GeniUncJ m 29.914 4.6492   7 1.7572 0.1554 21.6, 36.6 -0.33
CC040/TauUncJ f 26.613 1.6677   8 0.58962 0.0627 23.8, 28.9 -0.38
CC040/TauUncJ m 26.3 5.1691   7 1.9538 0.1965 17.2, 32.6 -0.93
CC041/TauUncJ f 26.812 4.8713   8 1.7223 0.1817 18.6, 34.4 -0.34
CC041/TauUncJ m 26.862 3.8022   8 1.3443 0.1415 22.6, 32.8 -0.84
CC051/TauUncJ f 37.743 15.399   7 5.8202 0.408 22.6, 63.2 1.46
CC051/TauUncJ m 30.633 9.298   9 3.0993 0.3035 23.6, 54.8 -0.21
CC068/TauUncJ f 32.74 15.06   5 6.7349 0.46 22.9, 59.2 0.63
CC068/TauUncJ m 23.65 3.4604   8 1.2234 0.1463 19.7, 30.6 -1.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 23.6625 4.0643 31.6766 15.6484
CC002/UncJ m 33.7 4.3449 42.2675 25.1325
CC003/UncJ f 41.06 5.141 51.1972 30.9228
CC003/UncJ m 28.85 5.7478 40.1837 17.5163
CC004/TauUncJ f 25.46 5.141 35.5972 15.3228
CC004/TauUncJ m 39.6 4.0643 47.6141 31.5859
CC006/TauUncJ f 27.725 5.7478 39.0587 16.3913
CC006/TauUncJ m 27.6875 4.0643 35.7016 19.6734
CC009/UncJ f 26.7375 4.0643 34.7516 18.7234
CC009/UncJ m 24.3625 4.0643 32.3766 16.3484
CC013/GeniUncJ f 24.75 4.0643 32.7641 16.7359
CC013/GeniUncJ m 41.6667 6.637 54.7537 28.5796
CC017/UncJ f 42.62 5.141 52.7572 32.4828
CC017/UncJ m 43.65 5.7478 54.9837 32.3163
CC018/UncJ f 23.7571 4.3449 32.3246 15.1897
CC018/UncJ m 31.35 4.0643 39.3641 23.3359
CC019/TauUncJ f 29.4625 4.0643 37.4766 21.4484
CC019/TauUncJ m 29.6625 4.0643 37.6766 21.6484
CC024/GeniUncJ f 26.2714 4.3449 34.8389 17.704
CC024/GeniUncJ m 30.5 4.0643 38.5141 22.4859
CC025/GeniUncJ f 20.14 5.141 30.2772 10.0028
CC025/GeniUncJ m 38.67 3.6352 45.8381 31.5019
CC026/GeniUncJ f 26.5286 4.3449 35.096 17.9611
CC026/GeniUncJ m 35.05 4.0643 43.0641 27.0359
CC032/GeniUncJ f 31.1 4.3449 39.6675 22.5325
CC032/GeniUncJ m 29.9143 4.3449 38.4818 21.3468
CC040/TauUncJ f 26.6125 4.0643 34.6266 18.5984
CC040/TauUncJ m 26.3 4.3449 34.8675 17.7325
CC041/TauUncJ f 26.8125 4.0643 34.8266 18.7984
CC041/TauUncJ m 26.8625 4.0643 34.8766 18.8484
CC051/TauUncJ f 37.7429 4.3449 46.3103 29.1754
CC051/TauUncJ m 30.6333 3.8319 38.1891 23.0775
CC068/TauUncJ f 32.74 5.141 42.8772 22.6028
CC068/TauUncJ m 23.65 4.0643 31.6641 15.6359


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 28.6813 2.9748 34.547 22.8155
CC003/UncJ both 34.955 3.8557 42.5579 27.3521
CC004/TauUncJ both 32.53 3.2767 38.9912 26.0688
CC006/TauUncJ both 27.7062 3.5198 34.6467 20.7658
CC009/UncJ both 25.55 2.8739 31.2169 19.8831
CC013/GeniUncJ both 33.2083 3.8913 40.8813 25.5354
CC017/UncJ both 43.135 3.8557 50.7379 35.5321
CC018/UncJ both 27.5536 2.9748 33.4193 21.6878
CC019/TauUncJ both 29.5625 2.8739 35.2294 23.8956
CC024/GeniUncJ both 28.3857 2.9748 34.2515 22.52
CC025/GeniUncJ both 29.405 3.1482 35.6127 23.1973
CC026/GeniUncJ both 30.7893 2.9748 36.655 24.9235
CC032/GeniUncJ both 30.5071 3.0723 36.5653 24.449
CC040/TauUncJ both 26.4563 2.9748 32.322 20.5905
CC041/TauUncJ both 26.8375 2.8739 32.5044 21.1706
CC051/TauUncJ both 34.1881 2.8966 39.8997 28.4764
CC068/TauUncJ both 28.195 3.2767 34.6562 21.7338




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA