Phenotype measure:   JaxCC1   AST

ID, description, units MPD:89188   AST   aspartate transaminase (plasma AST)   [IU/L]
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 17-19wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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JaxCC1 - aspartate transaminase (plasma AST)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means108.7   IU/L 93.93   IU/L
Median of the strain means96.41   IU/L 86.38   IU/L
SD of the strain means± 44.441 ± 27.08
Coefficient of variation (CV)0.4089 0.2883
Min–max range of strain means57.33   –   226.4   IU/L 61.6   –   163.0   IU/L
Mean sample size per strain6.1   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 20325.5048 20325.5048 2.7822 0.0971
strain 16 134713.0476 8419.5655 1.1525 0.311
sex:strain 16 136077.3881 8504.8368 1.1642 0.3011
Residuals 176 1285760.8405 7305.4593


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 96.0 63.99   8 22.623 0.6665 60.0, 253.0 -0.29
CC002/UncJ m 115.2 53.51   6 21.844 0.4646 51.0, 198.0 0.79
CC003/UncJ f 162.8 115.9   5 51.84 0.7121 59.0, 354.0 1.22
CC003/UncJ m 82.75 20.37   4 10.185 0.2462 69.0, 113.0 -0.41
CC004/TauUncJ f 113.2 85.55   8 30.248 0.7554 46.0, 299.0 0.1
CC004/TauUncJ m 125.4 63.35   8 22.398 0.5053 66.0, 252.0 1.16
CC006/TauUncJ f 57.33 11.719   3 6.7659 0.2044 44.0, 66.0 -1.16
CC006/TauUncJ m 81.43 34.583   7 13.071 0.4247 55.0, 146.0 -0.46
CC009/UncJ f 72.0 14.057   6 5.7388 0.1952 56.0, 93.0 -0.83
CC009/UncJ m 67.88 23.979   8 8.4778 0.3533 44.0, 102.0 -0.96
CC010/GeniUncJ f 113.2 23.656   4 11.828 0.2089 86.0, 140.0 0.1
CC013/GeniUncJ f 151.9 91.79   7 34.692 0.6044 75.0, 296.0 0.97
CC013/GeniUncJ m 111.0 54.11   3 31.241 0.4875 59.0, 167.0 0.63
CC017/UncJ f 105.4 24.926   5 11.147 0.2365 85.0, 147.0 -0.07
CC017/UncJ m 61.6 8.8769   5 3.9699 0.1441 51.0, 73.0 -1.19
CC018/UncJ f 77.57 26.999   7 10.205 0.3481 50.0, 130.0 -0.7
CC018/UncJ m 105.0 102.9   5 46.012 0.9799 57.0, 289.0 0.41
CC019/TauUncJ f 119.2 61.55   6 25.128 0.5165 75.0, 224.0 0.24
CC019/TauUncJ m 86.38 24.917   8 8.8094 0.2885 58.0, 137.0 -0.28
CC024/GeniUncJ f 96.83 9.411   6 3.842 0.0972 85.0, 110.0 -0.27
CC024/GeniUncJ m 91.29 35.612   7 13.46 0.3901 64.0, 158.0 -0.1
CC025/GeniUncJ f 79.25 36.728   4 18.364 0.4634 56.0, 134.0 -0.66
CC025/GeniUncJ m 116.5 69.03   10 21.83 0.5925 50.0, 271.0 0.83
CC026/GeniUncJ f 73.0 27.797   7 10.506 0.3808 38.0, 118.0 -0.8
CC026/GeniUncJ m 67.0 26.596   7 10.052 0.397 46.0, 125.0 -0.99
CC032/GeniUncJ f 60.17 19.156   6 7.8206 0.3184 40.0, 95.0 -1.09
CC032/GeniUncJ m 70.5 23.721   6 9.6842 0.3365 51.0, 116.0 -0.87
CC040/TauUncJ f 173.7 159.4   7 60.26 0.9178 53.0, 445.0 1.46
CC040/TauUncJ m 109.2 29.045   4 14.522 0.2659 69.0, 138.0 0.56
CC041/TauUncJ f 226.4 333.5   7 126.1 1.473 48.0, 973.0 2.65
CC041/TauUncJ m 70.88 40.657   8 14.374 0.5736 34.0, 158.0 -0.85
CC051/TauUncJ f 92.75 31.504   8 11.138 0.3397 60.0, 160.0 -0.36
CC051/TauUncJ m 71.83 30.321   6 12.379 0.4221 45.0, 128.0 -0.82
CC068/TauUncJ f 85.6 18.202   5 8.14 0.2126 62.0, 108.0 -0.52
CC068/TauUncJ m 163.0 160.3   3 92.52 0.9831 67.0, 348.0 2.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 96.0 30.2189 155.6381 36.3619
CC002/UncJ m 115.1667 34.8938 184.0308 46.3026
CC003/UncJ f 162.8 38.2242 238.2368 87.3632
CC003/UncJ m 82.75 42.736 167.0909 -1.5909
CC004/TauUncJ f 113.25 30.2189 172.8881 53.6119
CC004/TauUncJ m 125.375 30.2189 185.0131 65.7369
CC006/TauUncJ f 57.3333 49.3473 154.7219 -40.0552
CC006/TauUncJ m 81.4286 32.3054 145.1843 17.6728
CC009/UncJ f 72.0 34.8938 140.8641 3.1359
CC009/UncJ m 67.875 30.2189 127.5131 8.2369
CC013/GeniUncJ f 151.8571 32.3054 215.6129 88.1014
CC013/GeniUncJ m 111.0 49.3473 208.3885 13.6115
CC017/UncJ f 105.4 38.2242 180.8368 29.9632
CC017/UncJ m 61.6 38.2242 137.0368 -13.8368
CC018/UncJ f 77.5714 32.3054 141.3272 13.8157
CC018/UncJ m 105.0 38.2242 180.4368 29.5632
CC019/TauUncJ f 119.1667 34.8938 188.0308 50.3026
CC019/TauUncJ m 86.375 30.2189 146.0131 26.7369
CC024/GeniUncJ f 96.8333 34.8938 165.6974 27.9692
CC024/GeniUncJ m 91.2857 32.3054 155.0415 27.53
CC025/GeniUncJ f 79.25 42.736 163.5909 -5.0909
CC025/GeniUncJ m 116.5 27.0286 169.8419 63.1581
CC026/GeniUncJ f 73.0 32.3054 136.7558 9.2442
CC026/GeniUncJ m 67.0 32.3054 130.7558 3.2442
CC032/GeniUncJ f 60.1667 34.8938 129.0308 -8.6974
CC032/GeniUncJ m 70.5 34.8938 139.3641 1.6359
CC040/TauUncJ f 173.7143 32.3054 237.47 109.9585
CC040/TauUncJ m 109.25 42.736 193.5909 24.9091
CC041/TauUncJ f 226.4286 32.3054 290.1843 162.6728
CC041/TauUncJ m 70.875 30.2189 130.5131 11.2369
CC051/TauUncJ f 92.75 30.2189 152.3881 33.1119
CC051/TauUncJ m 71.8333 34.8938 140.6974 2.9692
CC068/TauUncJ f 85.6 38.2242 161.0368 10.1632
CC068/TauUncJ m 163.0 49.3473 260.3885 65.6115


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 105.5833 23.0801 151.1326 60.034
CC003/UncJ both 122.775 28.6682 179.3526 66.1974
CC004/TauUncJ both 119.3125 21.368 161.483 77.142
CC006/TauUncJ both 69.381 29.4906 127.5817 11.1802
CC009/UncJ both 69.9375 23.0801 115.4868 24.3882
CC013/GeniUncJ both 131.4286 29.4906 189.6294 73.2278
CC017/UncJ both 83.5 27.0286 136.8419 30.1581
CC018/UncJ both 91.2857 25.0236 140.6707 41.9007
CC019/TauUncJ both 102.7708 23.0801 148.3201 57.2215
CC024/GeniUncJ both 94.0595 23.7761 140.9825 47.1366
CC025/GeniUncJ both 97.875 25.283 147.7718 47.9782
CC026/GeniUncJ both 70.0 22.8433 115.0821 24.9179
CC032/GeniUncJ both 65.3333 24.6736 114.0276 16.6391
CC040/TauUncJ both 141.4821 26.7862 194.3456 88.6187
CC041/TauUncJ both 148.6518 22.118 192.3024 105.0012
CC051/TauUncJ both 82.2917 23.0801 127.841 36.7424
CC068/TauUncJ both 124.3 31.21 185.8939 62.7061




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA