Project measure / variable:   JaxCC1   QTc

ID, description, units MPD:89122   QTc   duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval   [ms]  
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 10-12wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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JaxCC1 - duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means44.405   ms 44.724   ms
Median of the strain means44.61   ms 44.675   ms
SD of the strain means± 1.472 ± 1.2882
Coefficient of variation (CV)0.0332 0.0288
Min–max range of strain means41.543   –   47.0   ms 42.387   –   47.825   ms
Mean sample size per strain6.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12.336 12.336 2.444 0.1195
strain 16 370.1894 23.1368 4.5839 < 0.0001
sex:strain 16 78.5789 4.9112 0.973 0.4877
Residuals 201 1014.5391 5.0475


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 44.237 2.7707   8 0.9796 0.0626 40.5, 48.3 -0.11
CC002/UncJ m 43.6 2.3594   7 0.89176 0.0541 38.8, 45.7 -0.87
CC003/UncJ f 45.6 1.1203   5 0.501 0.0246 44.1, 47.0 0.81
CC003/UncJ m 45.3 1.8312   4 0.91561 0.0404 43.4, 47.8 0.45
CC004/TauUncJ f 44.9 1.8748   5 0.83845 0.0418 42.7, 46.8 0.34
CC004/TauUncJ m 44.675 2.5184   8 0.89038 0.0564 40.4, 49.5 -0.04
CC006/TauUncJ f 44.675 2.2911   4 1.1456 0.0513 42.6, 47.8 0.18
CC006/TauUncJ m 45.3 1.5062   8 0.53251 0.0332 43.2, 47.3 0.45
CC009/UncJ f 45.25 1.5964   8 0.56442 0.0353 41.5, 46.7 0.57
CC009/UncJ m 47.825 1.745   8 0.61695 0.0365 44.9, 49.6 2.41
CC010/GeniUncJ f 44.94 1.3012   5 0.58189 0.029 43.2, 46.1 0.36
CC013/GeniUncJ f 44.45 1.5353   8 0.54281 0.0345 42.6, 47.6 0.03
CC013/GeniUncJ m 45.167 1.3503   3 0.7796 0.0299 43.8, 46.5 0.34
CC017/UncJ f 44.64 4.2969   5 1.9216 0.0963 39.9, 50.0 0.16
CC017/UncJ m 44.15 1.8664   4 0.93318 0.0423 41.5, 45.6 -0.45
CC018/UncJ f 46.243 1.8725   7 0.70773 0.0405 43.3, 48.3 1.25
CC018/UncJ m 45.688 1.5085   8 0.53333 0.033 43.7, 48.0 0.75
CC019/TauUncJ f 43.675 3.2504   8 1.1492 0.0744 38.9, 48.9 -0.5
CC019/TauUncJ m 42.387 3.0083   8 1.0636 0.071 38.5, 45.0 -1.81
CC024/GeniUncJ f 45.929 1.5392   7 0.58175 0.0335 43.5, 47.7 1.04
CC024/GeniUncJ m 46.075 2.0359   8 0.71981 0.0442 44.0, 49.8 1.05
CC025/GeniUncJ f 47.0 1.7378   5 0.77717 0.037 44.1, 48.8 1.76
CC025/GeniUncJ m 45.57 3.1899   10 1.0087 0.07 38.8, 48.9 0.66
CC026/GeniUncJ f 41.9 2.1471   7 0.81152 0.0512 38.6, 44.5 -1.7
CC026/GeniUncJ m 44.375 2.9441   8 1.0409 0.0663 40.9, 49.3 -0.27
CC032/GeniUncJ f 41.957 1.5306   7 0.57853 0.0365 39.4, 43.6 -1.66
CC032/GeniUncJ m 43.514 1.7199   7 0.65007 0.0395 41.2, 45.2 -0.94
CC040/TauUncJ f 43.888 2.2293   8 0.78818 0.0508 41.0, 47.5 -0.35
CC040/TauUncJ m 44.057 2.7682   7 1.0463 0.0628 39.7, 48.1 -0.52
CC041/TauUncJ f 43.875 1.3936   8 0.49271 0.0318 40.9, 45.3 -0.36
CC041/TauUncJ m 44.587 1.9052   8 0.67359 0.0427 41.6, 46.9 -0.11
CC051/TauUncJ f 41.543 2.1717   7 0.82082 0.0523 37.0, 43.6 -1.94
CC051/TauUncJ m 42.9 2.8054   9 0.93512 0.0654 38.4, 46.1 -1.42
CC068/TauUncJ f 44.58 1.1278   5 0.50438 0.0253 43.5, 45.9 0.12
CC068/TauUncJ m 45.138 1.741   8 0.61555 0.0386 43.4, 48.1 0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 44.2375 0.7943 45.8038 42.6712
CC002/UncJ m 43.6 0.8492 45.2744 41.9256
CC003/UncJ f 45.6 1.0047 47.5812 43.6188
CC003/UncJ m 45.3 1.1233 47.515 43.085
CC004/TauUncJ f 44.9 1.0047 46.8812 42.9188
CC004/TauUncJ m 44.675 0.7943 46.2413 43.1087
CC006/TauUncJ f 44.675 1.1233 46.89 42.46
CC006/TauUncJ m 45.3 0.7943 46.8663 43.7337
CC009/UncJ f 45.25 0.7943 46.8163 43.6837
CC009/UncJ m 47.825 0.7943 49.3913 46.2587
CC013/GeniUncJ f 44.45 0.7943 46.0163 42.8837
CC013/GeniUncJ m 45.1667 1.2971 47.7243 42.609
CC017/UncJ f 44.64 1.0047 46.6212 42.6588
CC017/UncJ m 44.15 1.1233 46.365 41.935
CC018/UncJ f 46.2429 0.8492 47.9173 44.5685
CC018/UncJ m 45.6875 0.7943 47.2538 44.1212
CC019/TauUncJ f 43.675 0.7943 45.2413 42.1087
CC019/TauUncJ m 42.3875 0.7943 43.9538 40.8212
CC024/GeniUncJ f 45.9286 0.8492 47.603 44.2542
CC024/GeniUncJ m 46.075 0.7943 47.6413 44.5087
CC025/GeniUncJ f 47.0 1.0047 48.9812 45.0188
CC025/GeniUncJ m 45.57 0.7105 46.9709 44.1691
CC026/GeniUncJ f 41.9 0.8492 43.5744 40.2256
CC026/GeniUncJ m 44.375 0.7943 45.9413 42.8087
CC032/GeniUncJ f 41.9571 0.8492 43.6315 40.2827
CC032/GeniUncJ m 43.5143 0.8492 45.1887 41.8399
CC040/TauUncJ f 43.8875 0.7943 45.4538 42.3212
CC040/TauUncJ m 44.0571 0.8492 45.7315 42.3827
CC041/TauUncJ f 43.875 0.7943 45.4413 42.3087
CC041/TauUncJ m 44.5875 0.7943 46.1538 43.0212
CC051/TauUncJ f 41.5429 0.8492 43.2173 39.8685
CC051/TauUncJ m 42.9 0.7489 44.3767 41.4233
CC068/TauUncJ f 44.58 1.0047 46.5612 42.5988
CC068/TauUncJ m 45.1375 0.7943 46.7038 43.5712


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 43.9188 0.5814 45.0651 42.7724
CC003/UncJ both 45.45 0.7536 46.9359 43.9641
CC004/TauUncJ both 44.7875 0.6404 46.0503 43.5247
CC006/TauUncJ both 44.9875 0.6879 46.3439 43.6311
CC009/UncJ both 46.5375 0.5617 47.645 45.43
CC013/GeniUncJ both 44.8083 0.7605 46.3079 43.3088
CC017/UncJ both 44.395 0.7536 45.8809 42.9091
CC018/UncJ both 45.9652 0.5814 47.1116 44.8188
CC019/TauUncJ both 43.0313 0.5617 44.1388 41.9237
CC024/GeniUncJ both 46.0018 0.5814 47.1482 44.8554
CC025/GeniUncJ both 46.285 0.6153 47.4982 45.0718
CC026/GeniUncJ both 43.1375 0.5814 44.2839 41.9911
CC032/GeniUncJ both 42.7357 0.6004 43.9197 41.5517
CC040/TauUncJ both 43.9723 0.5814 45.1187 42.8259
CC041/TauUncJ both 44.2313 0.5617 45.3388 43.1237
CC051/TauUncJ both 42.2214 0.5661 43.3377 41.1052
CC068/TauUncJ both 44.8588 0.6404 46.1215 43.596




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA