Project measure / variable:   JaxCC1   QT_dispersion

ID, description, units MPD:89123   QT_dispersion   QT dispersion, measured as inter-lead variability of QT intervals   [ms]  
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 10-12wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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JaxCC1 - QT dispersion, measured as inter-lead variability of QT intervals



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means25.173   ms 27.408   ms
Median of the strain means24.218   ms 27.0   ms
SD of the strain means± 5.04 ± 5.0819
Coefficient of variation (CV)0.2002 0.1854
Min–max range of strain means17.8   –   37.6   ms 20.125   –   36.333   ms
Mean sample size per strain6.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 273.381 273.381 3.0231 0.0836
strain 16 2239.7236 139.9827 1.548 0.0861
sex:strain 16 2807.9911 175.4994 1.9407 0.0187
Residuals 201 18176.3362 90.4295


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 19.562 3.8493   8 1.3609 0.1968 14.0, 24.5 -1.11
CC002/UncJ m 28.286 10.774   7 4.0721 0.3809 21.5, 51.5 0.17
CC003/UncJ f 37.6 18.619   5 8.3268 0.4952 20.0, 62.0 2.47
CC003/UncJ m 24.5 4.2032   4 2.1016 0.1716 19.0, 29.0 -0.57
CC004/TauUncJ f 22.5 5.5114   5 2.4648 0.2449 13.5, 26.5 -0.53
CC004/TauUncJ m 33.875 15.501   8 5.4803 0.4576 19.5, 58.0 1.27
CC006/TauUncJ f 24.125 2.136   4 1.068 0.0885 21.5, 26.5 -0.21
CC006/TauUncJ m 23.875 11.94   8 4.2213 0.5001 13.0, 50.0 -0.7
CC009/UncJ f 24.312 3.422   8 1.2098 0.1407 20.0, 29.0 -0.17
CC009/UncJ m 20.562 2.5416   8 0.8986 0.1236 17.0, 24.0 -1.35
CC010/GeniUncJ f 24.7 4.8296   5 2.1599 0.1955 20.0, 32.5 -0.09
CC013/GeniUncJ f 22.062 2.2747   8 0.80422 0.1031 18.5, 24.5 -0.62
CC013/GeniUncJ m 36.333 18.791   3 10.849 0.5172 24.5, 58.0 1.76
CC017/UncJ f 36.1 15.626   5 6.9882 0.4329 24.5, 56.5 2.17
CC017/UncJ m 35.75 15.602   4 7.8009 0.4364 25.5, 59.0 1.64
CC018/UncJ f 20.857 2.5774   7 0.97416 0.1236 17.0, 24.5 -0.86
CC018/UncJ m 27.625 12.586   8 4.4499 0.4556 18.5, 58.0 0.04
CC019/TauUncJ f 25.25 8.5899   8 3.037 0.3402 16.0, 45.0 0.02
CC019/TauUncJ m 25.125 11.348   8 4.012 0.4516 19.5, 53.0 -0.45
CC024/GeniUncJ f 23.857 4.9809   7 1.8826 0.2088 17.5, 33.0 -0.26
CC024/GeniUncJ m 27.5 4.1833   8 1.479 0.1521 21.0, 31.5 0.02
CC025/GeniUncJ f 17.8 5.7836   5 2.5865 0.3249 9.5, 25.0 -1.46
CC025/GeniUncJ m 35.1 20.867   10 6.5987 0.5945 17.5, 81.5 1.51
CC026/GeniUncJ f 23.357 2.9399   7 1.1112 0.1259 20.5, 29.0 -0.36
CC026/GeniUncJ m 27.812 10.633   8 3.7594 0.3823 19.0, 53.0 0.08
CC032/GeniUncJ f 26.071 13.049   7 4.9322 0.5005 17.0, 55.0 0.18
CC032/GeniUncJ m 27.0 4.5092   7 1.7043 0.167 19.5, 33.5 -0.08
CC040/TauUncJ f 23.562 1.5684   8 0.55451 0.0666 21.0, 25.5 -0.32
CC040/TauUncJ m 22.643 4.1404   7 1.5649 0.1829 15.0, 27.5 -0.94
CC041/TauUncJ f 24.438 4.387   8 1.551 0.1795 17.5, 31.0 -0.15
CC041/TauUncJ m 24.375 3.8522   8 1.362 0.158 20.5, 30.0 -0.6
CC051/TauUncJ f 29.857 9.3306   7 3.5266 0.3125 20.5, 45.5 0.93
CC051/TauUncJ m 25.444 3.0766   9 1.0255 0.1209 21.0, 31.5 -0.39
CC068/TauUncJ f 27.1 12.651   5 5.6577 0.4668 19.0, 49.5 0.38
CC068/TauUncJ m 20.125 3.1707   8 1.121 0.1576 16.5, 26.5 -1.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 19.5625 3.3621 26.192 12.933
CC002/UncJ m 28.2857 3.5942 35.373 21.1985
CC003/UncJ f 37.6 4.2528 45.9857 29.2143
CC003/UncJ m 24.5 4.7547 33.8755 15.1245
CC004/TauUncJ f 22.5 4.2528 30.8857 14.1143
CC004/TauUncJ m 33.875 3.3621 40.5045 27.2455
CC006/TauUncJ f 24.125 4.7547 33.5005 14.7495
CC006/TauUncJ m 23.875 3.3621 30.5045 17.2455
CC009/UncJ f 24.3125 3.3621 30.942 17.683
CC009/UncJ m 20.5625 3.3621 27.192 13.933
CC013/GeniUncJ f 22.0625 3.3621 28.692 15.433
CC013/GeniUncJ m 36.3333 5.4903 47.1593 25.5074
CC017/UncJ f 36.1 4.2528 44.4857 27.7143
CC017/UncJ m 35.75 4.7547 45.1255 26.3745
CC018/UncJ f 20.8571 3.5942 27.9444 13.7699
CC018/UncJ m 27.625 3.3621 34.2545 20.9955
CC019/TauUncJ f 25.25 3.3621 31.8795 18.6205
CC019/TauUncJ m 25.125 3.3621 31.7545 18.4955
CC024/GeniUncJ f 23.8571 3.5942 30.9444 16.7699
CC024/GeniUncJ m 27.5 3.3621 34.1295 20.8705
CC025/GeniUncJ f 17.8 4.2528 26.1857 9.4143
CC025/GeniUncJ m 35.1 3.0072 41.0296 29.1704
CC026/GeniUncJ f 23.3571 3.5942 30.4444 16.2699
CC026/GeniUncJ m 27.8125 3.3621 34.442 21.183
CC032/GeniUncJ f 26.0714 3.5942 33.1587 18.9842
CC032/GeniUncJ m 27.0 3.5942 34.0872 19.9128
CC040/TauUncJ f 23.5625 3.3621 30.192 16.933
CC040/TauUncJ m 22.6429 3.5942 29.7301 15.5556
CC041/TauUncJ f 24.4375 3.3621 31.067 17.808
CC041/TauUncJ m 24.375 3.3621 31.0045 17.7455
CC051/TauUncJ f 29.8571 3.5942 36.9444 22.7699
CC051/TauUncJ m 25.4444 3.1698 31.6948 19.1941
CC068/TauUncJ f 27.1 4.2528 35.4857 18.7143
CC068/TauUncJ m 20.125 3.3621 26.7545 13.4955


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 23.9241 2.4608 28.7764 19.0718
CC003/UncJ both 31.05 3.1896 37.3393 24.7607
CC004/TauUncJ both 28.1875 2.7106 33.5324 22.8426
CC006/TauUncJ both 24.0 2.9117 29.7413 18.2587
CC009/UncJ both 22.4375 2.3774 27.1253 17.7497
CC013/GeniUncJ both 29.1979 3.219 35.5452 22.8506
CC017/UncJ both 35.925 3.1896 42.2143 29.6357
CC018/UncJ both 24.2411 2.4608 29.0934 19.3888
CC019/TauUncJ both 25.1875 2.3774 29.8753 20.4997
CC024/GeniUncJ both 25.6786 2.4608 30.5309 20.8263
CC025/GeniUncJ both 26.45 2.6043 31.5852 21.3148
CC026/GeniUncJ both 25.5848 2.4608 30.4371 20.7325
CC032/GeniUncJ both 26.5357 2.5415 31.5471 21.5243
CC040/TauUncJ both 23.1027 2.4608 27.955 18.2504
CC041/TauUncJ both 24.4063 2.3774 29.094 19.7185
CC051/TauUncJ both 27.6508 2.3962 32.3756 22.926
CC068/TauUncJ both 23.6125 2.7106 28.9574 18.2676




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA