Project measure / variable:   JaxCC1   QT

ID, description, units MPD:89120   QT   duration of QT interval   [ms]  
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 10-12wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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JaxCC1 - duration of QT interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means39.014   ms 39.248   ms
Median of the strain means39.32   ms 39.137   ms
SD of the strain means± 1.6811 ± 1.5803
Coefficient of variation (CV)0.0431 0.0403
Min–max range of strain means36.2   –   41.429   ms 35.938   –   42.375   ms
Mean sample size per strain6.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8.2679 8.2679 1.4718 0.2265
strain 16 565.6631 35.3539 6.2935 < 0.0001
sex:strain 16 60.0084 3.7505 0.6676 0.8237
Residuals 201 1129.1204 5.6175


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 37.362 2.4295   8 0.85897 0.065 34.3, 41.5 -0.98
CC002/UncJ m 36.971 2.2699   7 0.85794 0.0614 32.4, 39.7 -1.44
CC003/UncJ f 40.42 1.8633   5 0.83331 0.0461 37.6, 42.8 0.84
CC003/UncJ m 40.0 1.547   4 0.77352 0.0387 38.3, 42.0 0.48
CC004/TauUncJ f 39.44 2.1408   5 0.95739 0.0543 37.1, 41.6 0.25
CC004/TauUncJ m 38.663 2.7297   8 0.96509 0.0706 34.0, 43.0 -0.37
CC006/TauUncJ f 39.2 3.9682   4 1.9841 0.1012 36.5, 45.1 0.11
CC006/TauUncJ m 39.137 1.2861   8 0.45471 0.0329 37.3, 41.0 -0.07
CC009/UncJ f 41.25 1.5353   8 0.54281 0.0372 37.9, 42.6 1.33
CC009/UncJ m 42.375 1.7774   8 0.62842 0.0419 39.7, 44.0 1.98
CC010/GeniUncJ f 40.76 1.692   5 0.7567 0.0415 38.2, 42.9 1.04
CC013/GeniUncJ f 39.487 1.3196   8 0.46654 0.0334 38.2, 42.1 0.28
CC013/GeniUncJ m 39.9 1.6523   3 0.95394 0.0414 38.3, 41.6 0.41
CC017/UncJ f 39.14 3.8604   5 1.7264 0.0986 34.7, 43.5 0.07
CC017/UncJ m 38.675 1.646   4 0.82298 0.0426 36.3, 40.0 -0.36
CC018/UncJ f 40.2 2.2219   7 0.83978 0.0553 37.5, 42.9 0.71
CC018/UncJ m 39.975 2.3627   8 0.83533 0.0591 38.0, 44.0 0.46
CC019/TauUncJ f 37.425 3.3324   8 1.1782 0.089 32.9, 42.7 -0.95
CC019/TauUncJ m 35.938 3.2474   8 1.1481 0.0904 31.6, 39.1 -2.09
CC024/GeniUncJ f 41.429 1.5808   7 0.5975 0.0382 38.6, 42.9 1.44
CC024/GeniUncJ m 41.762 1.7484   8 0.61816 0.0419 39.8, 44.6 1.59
CC025/GeniUncJ f 40.32 1.1735   5 0.52479 0.0291 38.4, 41.6 0.78
CC025/GeniUncJ m 40.15 3.7751   10 1.1938 0.094 33.3, 45.6 0.57
CC026/GeniUncJ f 36.629 2.1305   7 0.80525 0.0582 33.3, 39.1 -1.42
CC026/GeniUncJ m 38.737 2.9491   8 1.0427 0.0761 35.7, 44.1 -0.32
CC032/GeniUncJ f 36.2 1.481   7 0.55976 0.0409 34.3, 38.2 -1.67
CC032/GeniUncJ m 38.643 1.6185   7 0.61173 0.0419 36.2, 40.4 -0.38
CC040/TauUncJ f 38.925 2.2914   8 0.81015 0.0589 35.8, 42.3 -0.05
CC040/TauUncJ m 39.514 3.3692   7 1.2734 0.0853 35.3, 45.5 0.17
CC041/TauUncJ f 39.925 1.6867   8 0.59634 0.0422 36.9, 42.0 0.54
CC041/TauUncJ m 40.413 2.3691   8 0.83761 0.0586 37.1, 43.8 0.74
CC051/TauUncJ f 36.243 2.3691   7 0.89545 0.0654 31.6, 39.4 -1.65
CC051/TauUncJ m 37.744 2.6698   9 0.88993 0.0707 33.5, 40.7 -0.95
CC068/TauUncJ f 37.9 0.67454   5 0.30166 0.0178 37.0, 38.6 -0.66
CC068/TauUncJ m 38.625 1.6263   8 0.575 0.0421 37.0, 40.8 -0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 37.3625 0.838 39.0148 35.7102
CC002/UncJ m 36.9714 0.8958 38.7378 35.205
CC003/UncJ f 40.42 1.06 42.5101 38.3299
CC003/UncJ m 40.0 1.1851 42.3368 37.6632
CC004/TauUncJ f 39.44 1.06 41.5301 37.3499
CC004/TauUncJ m 38.6625 0.838 40.3148 37.0102
CC006/TauUncJ f 39.2 1.1851 41.5368 36.8632
CC006/TauUncJ m 39.1375 0.838 40.7898 37.4852
CC009/UncJ f 41.25 0.838 42.9023 39.5977
CC009/UncJ m 42.375 0.838 44.0273 40.7227
CC013/GeniUncJ f 39.4875 0.838 41.1398 37.8352
CC013/GeniUncJ m 39.9 1.3684 42.5983 37.2017
CC017/UncJ f 39.14 1.06 41.2301 37.0499
CC017/UncJ m 38.675 1.1851 41.0118 36.3382
CC018/UncJ f 40.2 0.8958 41.9664 38.4336
CC018/UncJ m 39.975 0.838 41.6273 38.3227
CC019/TauUncJ f 37.425 0.838 39.0773 35.7727
CC019/TauUncJ m 35.9375 0.838 37.5898 34.2852
CC024/GeniUncJ f 41.4286 0.8958 43.195 39.6622
CC024/GeniUncJ m 41.7625 0.838 43.4148 40.1102
CC025/GeniUncJ f 40.32 1.06 42.4101 38.2299
CC025/GeniUncJ m 40.15 0.7495 41.6279 38.6721
CC026/GeniUncJ f 36.6286 0.8958 38.395 34.8622
CC026/GeniUncJ m 38.7375 0.838 40.3898 37.0852
CC032/GeniUncJ f 36.2 0.8958 37.9664 34.4336
CC032/GeniUncJ m 38.6429 0.8958 40.4093 36.8764
CC040/TauUncJ f 38.925 0.838 40.5773 37.2727
CC040/TauUncJ m 39.5143 0.8958 41.2807 37.7479
CC041/TauUncJ f 39.925 0.838 41.5773 38.2727
CC041/TauUncJ m 40.4125 0.838 42.0648 38.7602
CC051/TauUncJ f 36.2429 0.8958 38.0093 34.4764
CC051/TauUncJ m 37.7444 0.79 39.3023 36.1866
CC068/TauUncJ f 37.9 1.06 39.9901 35.8099
CC068/TauUncJ m 38.625 0.838 40.2773 36.9727


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 37.167 0.6133 38.3763 35.9576
CC003/UncJ both 40.21 0.795 41.7775 38.6425
CC004/TauUncJ both 39.0512 0.6756 40.3834 37.7191
CC006/TauUncJ both 39.1687 0.7257 40.5997 37.7378
CC009/UncJ both 41.8125 0.5925 42.9809 40.6441
CC013/GeniUncJ both 39.6937 0.8023 41.2757 38.1118
CC017/UncJ both 38.9075 0.795 40.475 37.34
CC018/UncJ both 40.0875 0.6133 41.2969 38.8781
CC019/TauUncJ both 36.6812 0.5925 37.8496 35.5129
CC024/GeniUncJ both 41.5955 0.6133 42.8049 40.3862
CC025/GeniUncJ both 40.235 0.6491 41.5149 38.9551
CC026/GeniUncJ both 37.683 0.6133 38.8924 36.4737
CC032/GeniUncJ both 37.4214 0.6334 38.6705 36.1724
CC040/TauUncJ both 39.2196 0.6133 40.429 38.0103
CC041/TauUncJ both 40.1687 0.5925 41.3371 39.0004
CC051/TauUncJ both 36.9937 0.5972 38.1713 35.816
CC068/TauUncJ both 38.2625 0.6756 39.5947 36.9303




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA