Project measure / variable:   JaxCC1   PPI_slope

ID, description, units MPD:89078   PPI_slope   maximum slope for percent prepulse inhibition (PPI) averages (74, 78, 82 dB), adjusted for background noise    
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 9-11wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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JaxCC1 - maximum slope for percent prepulse inhibition (PPI) averages (74, 78, 82 dB), adjusted for background noise



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means0.09633   None 0.02035   None
Median of the strain means0.0619   None 0.04901   None
SD of the strain means± 0.13365 ± 0.14271
Coefficient of variation (CV)1.3875 7.0135
Min–max range of strain means0.01131   –   0.6125   None -0.51883   –   0.1281   None
Mean sample size per strain7.0   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1583 0.1583 2.8389 0.0935
strain 16 0.6914 0.0432 0.7748 0.7132
sex:strain 16 2.0023 0.1251 2.2437 0.005
Residuals 214 11.936 0.0558


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 0.07283 0.02862   8 0.01012 0.3929 0.04609, 0.11511 -0.18
CC002/UncJ m 0.05353 0.04919   7 0.01859 0.9188 -0.03308, 0.10379 0.23
CC003/UncJ f 0.10188 0.03977   5 0.01779 0.3904 0.07104, 0.16963 0.04
CC003/UncJ m 0.1281 0.04291   4 0.02146 0.335 0.09762, 0.19118 0.76
CC004/TauUncJ f 0.05139 0.02737   8 0.00967668 0.5326 0.02709, 0.11605 -0.34
CC004/TauUncJ m 0.06794 0.02898   8 0.01025 0.4266 0.03125, 0.12189 0.33
CC006/TauUncJ f 0.6125 1.1751   4 0.58755 1.9185 0.01389, 2.375 3.86
CC006/TauUncJ m 0.02465 0.13029   8 0.04606 5.2858 -0.15625, 0.3 0.03
CC009/UncJ f 0.04073 0.02   8 0.00707001 0.491 0.01757, 0.07353 -0.42
CC009/UncJ m 0.05421 0.04852   8 0.01715 0.895 0.0137, 0.14078 0.24
CC010/GeniUncJ f 0.0608 0.02105   5 0.0094124 0.3461 0.03054, 0.08601 -0.27
CC013/GeniUncJ f 0.17221 0.52567   8 0.18585 3.0524 -0.17708, 1.4375 0.57
CC013/GeniUncJ m -0.51883 1.3462   4 0.67312 -2.5948 -2.5156, 0.43056 -3.78
CC017/UncJ f 0.07627 0.03203   6 0.01307 0.4199 0.02806, 0.123 -0.15
CC017/UncJ m 0.04901 0.01405   5 0.00628464 0.2867 0.03467, 0.07004 0.2
CC018/UncJ f 0.03189 0.02889   8 0.01021 0.9059 -0.00484581, 0.08842 -0.48
CC018/UncJ m 0.03499 0.02764   8 0.00977128 0.7899 -0.00499201, 0.07127 0.1
CC019/TauUncJ f 0.07419 0.0149   8 0.00526757 0.2008 0.04539, 0.08812 -0.17
CC019/TauUncJ m 0.043 0.04969   8 0.01757 1.1555 -0.04337, 0.12863 0.16
CC024/GeniUncJ f 0.03261 0.01416   7 0.0053509 0.4341 0.01344, 0.05053 -0.48
CC024/GeniUncJ m 0.02748 0.01874   8 0.00662559 0.682 -0.00108819, 0.05881 0.05
CC025/GeniUncJ f 0.04799 0.03323   6 0.01357 0.6925 -0.0093985, 0.0825 -0.36
CC025/GeniUncJ m 0.05626 0.06265   10 0.01981 1.1136 -0.03309, 0.17102 0.25
CC026/GeniUncJ f 0.06842 0.02211   8 0.00781725 0.3232 0.04383, 0.10091 -0.21
CC026/GeniUncJ m 0.04559 0.02   8 0.00707275 0.4388 0.01725, 0.0694 0.18
CC032/GeniUncJ f 0.01131 0.03463   8 0.01224 3.0606 -0.02699, 0.07862 -0.64
CC032/GeniUncJ m -0.01518 0.05187   8 0.01834 -3.4175 -0.11529, 0.06066 -0.25
CC040/TauUncJ f 0.04662 0.06032   8 0.02133 1.2938 -0.01182, 0.16297 -0.37
CC040/TauUncJ m 0.08622 0.10815   7 0.04088 1.2544 -0.04924, 0.24194 0.46
CC041/TauUncJ f 0.10942 0.02677   8 0.00946381 0.2446 0.07264, 0.13943 0.1
CC041/TauUncJ m 0.11052 0.03724   8 0.01317 0.337 0.04593, 0.15731 0.63
CC051/TauUncJ f 0.05983 0.03451   8 0.0122 0.5768 -0.00044563, 0.10862 -0.27
CC051/TauUncJ m 0.04342 0.01709   10 0.0054028 0.3935 0.01484, 0.07128 0.16
CC068/TauUncJ f 0.06299 0.02584   5 0.01155 0.4102 0.02885, 0.09935 -0.25
CC068/TauUncJ m 0.055 0.01983   8 0.00701122 0.3605 0.03122, 0.09485 0.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 0.0728 0.0835 0.2374 -0.0918
CC002/UncJ m 0.0535 0.0893 0.2295 -0.1224
CC003/UncJ f 0.1019 0.1056 0.3101 -0.1063
CC003/UncJ m 0.1281 0.1181 0.3609 -0.1047
CC004/TauUncJ f 0.0514 0.0835 0.216 -0.1132
CC004/TauUncJ m 0.0679 0.0835 0.2325 -0.0966
CC006/TauUncJ f 0.6125 0.1181 0.8453 0.3797
CC006/TauUncJ m 0.0246 0.0835 0.1892 -0.1399
CC009/UncJ f 0.0407 0.0835 0.2053 -0.1239
CC009/UncJ m 0.0542 0.0835 0.2188 -0.1104
CC013/GeniUncJ f 0.1722 0.0835 0.3368 0.0076
CC013/GeniUncJ m -0.5188 0.1181 -0.2861 -0.7516
CC017/UncJ f 0.0763 0.0964 0.2663 -0.1138
CC017/UncJ m 0.049 0.1056 0.2572 -0.1592
CC018/UncJ f 0.0319 0.0835 0.1965 -0.1327
CC018/UncJ m 0.035 0.0835 0.1996 -0.1296
CC019/TauUncJ f 0.0742 0.0835 0.2388 -0.0904
CC019/TauUncJ m 0.043 0.0835 0.2076 -0.1216
CC024/GeniUncJ f 0.0326 0.0893 0.2086 -0.1433
CC024/GeniUncJ m 0.0275 0.0835 0.1921 -0.1371
CC025/GeniUncJ f 0.048 0.0964 0.238 -0.1421
CC025/GeniUncJ m 0.0563 0.0747 0.2035 -0.0909
CC026/GeniUncJ f 0.0684 0.0835 0.233 -0.0962
CC026/GeniUncJ m 0.0456 0.0835 0.2102 -0.119
CC032/GeniUncJ f 0.0113 0.0835 0.1759 -0.1533
CC032/GeniUncJ m -0.0152 0.0835 0.1494 -0.1798
CC040/TauUncJ f 0.0466 0.0835 0.2112 -0.118
CC040/TauUncJ m 0.0862 0.0893 0.2622 -0.0897
CC041/TauUncJ f 0.1094 0.0835 0.274 -0.0552
CC041/TauUncJ m 0.1105 0.0835 0.2751 -0.0541
CC051/TauUncJ f 0.0598 0.0835 0.2244 -0.1048
CC051/TauUncJ m 0.0434 0.0747 0.1906 -0.1038
CC068/TauUncJ f 0.063 0.1056 0.2712 -0.1452
CC068/TauUncJ m 0.055 0.0835 0.2196 -0.1096


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 0.0632 0.0611 0.1836 -0.0573
CC003/UncJ both 0.115 0.0792 0.2711 -0.0412
CC004/TauUncJ both 0.0597 0.059 0.176 -0.0567
CC006/TauUncJ both 0.3186 0.0723 0.4611 0.176
CC009/UncJ both 0.0475 0.059 0.1639 -0.0689
CC013/GeniUncJ both -0.1733 0.0723 -0.0308 -0.3158
CC017/UncJ both 0.0626 0.0715 0.2036 -0.0783
CC018/UncJ both 0.0334 0.059 0.1498 -0.0829
CC019/TauUncJ both 0.0586 0.059 0.175 -0.0578
CC024/GeniUncJ both 0.03 0.0611 0.1505 -0.0904
CC025/GeniUncJ both 0.0521 0.061 0.1723 -0.0681
CC026/GeniUncJ both 0.057 0.059 0.1734 -0.0594
CC032/GeniUncJ both -0.0019 0.059 0.1144 -0.1183
CC040/TauUncJ both 0.0664 0.0611 0.1869 -0.054
CC041/TauUncJ both 0.11 0.059 0.2263 -0.0064
CC051/TauUncJ both 0.0516 0.056 0.162 -0.0588
CC068/TauUncJ both 0.059 0.0673 0.1917 -0.0737




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA