Phenotype measure:   JaxCC1   AST_ALT_ratio

ID, description, units MPD:89189   AST_ALT_ratio   aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)   [ratio]
Data set, strains JaxCC1   CC   18 strains     sex: both     age: 17-19wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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JaxCC1 - aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means2.1192   ratio 1.7905   ratio
Median of the strain means1.9579   ratio 1.7837   ratio
SD of the strain means± 0.62857 ± 0.52437
Coefficient of variation (CV)0.2966 0.2929
Min–max range of strain means1.1539   –   3.6622   ratio 0.76283   –   2.5682   ratio
Mean sample size per strain6.1   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.9643 3.9643 7.0577 0.0086
strain 16 54.6072 3.413 6.0762 < 0.0001
sex:strain 16 12.1592 0.76 1.353 0.1704
Residuals 176 98.8582 0.5617


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/UncJ f 1.6751 0.69473   8 0.24563 0.4147 0.374, 2.593 -0.71
CC002/UncJ m 0.76283 0.23506   6 0.09596 0.3081 0.496, 1.107 -1.96
CC003/UncJ f 3.6622 2.0964   5 0.93756 0.5725 1.475, 6.556 2.45
CC003/UncJ m 2.5682 0.64229   4 0.32114 0.2501 2.226, 3.531 1.48
CC004/TauUncJ f 2.645 1.0592   8 0.37448 0.4005 1.729, 4.45 0.84
CC004/TauUncJ m 2.4398 1.1277   8 0.39869 0.4622 1.237, 3.938 1.24
CC006/TauUncJ f 1.736 0.07621   3 0.044 0.0439 1.692, 1.824 -0.61
CC006/TauUncJ m 2.5243 1.5067   7 0.56946 0.5969 1.309, 4.818 1.4
CC009/UncJ f 2.2752 0.5002   6 0.20421 0.2199 1.7, 3.0 0.25
CC009/UncJ m 1.5036 0.36016   8 0.12734 0.2395 1.257, 2.353 -0.55
CC010/GeniUncJ f 2.4963 0.76933   4 0.38466 0.3082 2.048, 3.647 0.6
CC013/GeniUncJ f 1.1539 0.28546   7 0.1079 0.2474 0.795, 1.576 -1.54
CC013/GeniUncJ m 1.7947 0.7364   3 0.42516 0.4103 0.983, 2.42 0.01
CC017/UncJ f 2.767 0.22743   5 0.10171 0.0822 2.5, 3.114 1.03
CC017/UncJ m 2.115 0.29233   5 0.13073 0.1382 1.774, 2.433 0.62
CC018/UncJ f 2.0343 0.60762   7 0.22966 0.2987 1.255, 3.023 -0.14
CC018/UncJ m 1.9784 0.94545   5 0.42282 0.4779 1.235, 3.613 0.36
CC019/TauUncJ f 2.4697 1.0305   6 0.4207 0.4173 1.607, 4.308 0.56
CC019/TauUncJ m 2.0645 0.30216   8 0.10683 0.1464 1.702, 2.667 0.52
CC024/GeniUncJ f 1.641 0.44029   6 0.17975 0.2683 1.076, 2.106 -0.76
CC024/GeniUncJ m 1.4253 0.39674   7 0.14995 0.2784 0.941, 2.107 -0.7
CC025/GeniUncJ f 1.7652 0.91011   4 0.45506 0.5156 1.151, 3.116 -0.56
CC025/GeniUncJ m 2.317 0.80404   10 0.25426 0.347 1.0, 3.346 1.0
CC026/GeniUncJ f 1.7586 0.47305   7 0.1788 0.269 1.195, 2.45 -0.57
CC026/GeniUncJ m 1.6643 0.13178   7 0.04981 0.0792 1.476, 1.894 -0.24
CC032/GeniUncJ f 1.453 0.32881   6 0.13423 0.2263 1.203, 2.103 -1.06
CC032/GeniUncJ m 1.1247 0.28958   6 0.11822 0.2575 0.709, 1.571 -1.27
CC040/TauUncJ f 2.3454 0.89302   7 0.33753 0.3807 1.559, 4.083 0.36
CC040/TauUncJ m 1.7472 0.95355   4 0.47677 0.5457 0.651, 2.936 -0.08
CC041/TauUncJ f 1.4789 0.48214   7 0.18223 0.326 0.853, 2.286 -1.02
CC041/TauUncJ m 1.037 0.36982   8 0.13075 0.3566 0.449, 1.634 -1.44
CC051/TauUncJ f 1.8816 0.68179   8 0.24105 0.3623 1.393, 3.438 -0.38
CC051/TauUncJ m 1.5883 0.45462   6 0.1856 0.2862 1.216, 2.327 -0.39
CC068/TauUncJ f 2.9078 0.87731   5 0.39235 0.3017 2.067, 4.32 1.25
CC068/TauUncJ m 1.7837 0.24908   3 0.14381 0.1396 1.574, 2.059 -0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ f 1.6751 0.265 2.1981 1.1522
CC002/UncJ m 0.7628 0.306 1.3667 0.159
CC003/UncJ f 3.6622 0.3352 4.3237 3.0007
CC003/UncJ m 2.5682 0.3747 3.3078 1.8287
CC004/TauUncJ f 2.645 0.265 3.1679 2.1221
CC004/TauUncJ m 2.4397 0.265 2.9627 1.9168
CC006/TauUncJ f 1.736 0.4327 2.59 0.882
CC006/TauUncJ m 2.5243 0.2833 3.0833 1.9652
CC009/UncJ f 2.2752 0.306 2.879 1.6713
CC009/UncJ m 1.5036 0.265 2.0266 0.9807
CC013/GeniUncJ f 1.1539 0.2833 1.7129 0.5948
CC013/GeniUncJ m 1.7947 0.4327 2.6486 0.9407
CC017/UncJ f 2.767 0.3352 3.4285 2.1055
CC017/UncJ m 2.115 0.3352 2.7765 1.4535
CC018/UncJ f 2.0343 0.2833 2.5933 1.4752
CC018/UncJ m 1.9784 0.3352 2.6399 1.3169
CC019/TauUncJ f 2.4697 0.306 3.0735 1.8658
CC019/TauUncJ m 2.0645 0.265 2.5874 1.5416
CC024/GeniUncJ f 1.641 0.306 2.2448 1.0372
CC024/GeniUncJ m 1.4253 0.2833 1.9843 0.8662
CC025/GeniUncJ f 1.7652 0.3747 2.5048 1.0257
CC025/GeniUncJ m 2.317 0.237 2.7847 1.8493
CC026/GeniUncJ f 1.7586 0.2833 2.3176 1.1995
CC026/GeniUncJ m 1.6643 0.2833 2.2233 1.1052
CC032/GeniUncJ f 1.453 0.306 2.0568 0.8492
CC032/GeniUncJ m 1.1247 0.306 1.7285 0.5208
CC040/TauUncJ f 2.3454 0.2833 2.9045 1.7864
CC040/TauUncJ m 1.7473 0.3747 2.4868 1.0077
CC041/TauUncJ f 1.4789 0.2833 2.0379 0.9198
CC041/TauUncJ m 1.037 0.265 1.5599 0.5141
CC051/TauUncJ f 1.8816 0.265 2.4046 1.3587
CC051/TauUncJ m 1.5883 0.306 2.1922 0.9845
CC068/TauUncJ f 2.9078 0.3352 3.5693 2.2463
CC068/TauUncJ m 1.7837 0.4327 2.6376 0.9297


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/UncJ both 1.219 0.2024 1.6184 0.8196
CC003/UncJ both 3.1152 0.2514 3.6113 2.6191
CC004/TauUncJ both 2.5424 0.1874 2.9121 2.1726
CC006/TauUncJ both 2.1301 0.2586 2.6405 1.6198
CC009/UncJ both 1.8894 0.2024 2.2888 1.49
CC013/GeniUncJ both 1.4743 0.2586 1.9846 0.9639
CC017/UncJ both 2.441 0.237 2.9087 1.9733
CC018/UncJ both 2.0063 0.2194 2.4394 1.5733
CC019/TauUncJ both 2.2671 0.2024 2.6665 1.8677
CC024/GeniUncJ both 1.5331 0.2085 1.9446 1.1217
CC025/GeniUncJ both 2.0411 0.2217 2.4786 1.6036
CC026/GeniUncJ both 1.7114 0.2003 2.1067 1.3161
CC032/GeniUncJ both 1.2888 0.2164 1.7158 0.8619
CC040/TauUncJ both 2.0463 0.2349 2.5099 1.5828
CC041/TauUncJ both 1.2579 0.1939 1.6407 0.8752
CC051/TauUncJ both 1.735 0.2024 2.1344 1.3356
CC068/TauUncJ both 2.3457 0.2737 2.8858 1.8056




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA