Studies associated with ontology term
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Data set Procedure What's in this data set Panel Sex Age (weeks) Year
Ackerman1 study archive
with methacholine 		Lung, respiratory function, baseline and methacholine-challenged (several doses). QTL population f 7-8wks 2005
Ankra-Badu1 study archive Body, organ, fat pad weights, weight gain, litter size. QTL population both 2-10wks 2009
Attie2 hormone quantification
with high-fat high-sucrose diet 		Plasma insulin, adiponectin, leptin. Ex vivo insulin secretion. DO population both 4-26wks 2018
Attie2 microscopy
with high-fat high-sucrose diet 		Number of islets harvested. DO population both 4-26wks 2018
Attie2 organ weights
with high-fat high-sucrose diet 		Heart, liver, gonadal fat pads. DO population both 4-26wks 2018
Auwerx1 tail cuff
with high-fat diet 		Blood pressure and heart rate. BXD w/par   (57) m 8-29 wks 2016
Auwerx1 organ weights
with high-fat diet 		Skeletal muscle, soleus muscle, heart, kidney, liver, various fat pads. BXD w/par   (57) m 8-29 wks 2016
Auwerx2 organ weights
with high-fat diet 		Cecum, muscles, heart, heart-atria, kidney, liver, spleen, fat pads. inbred w/CC8 both 8-21 wks 2021
Auwerx2 organ dimensions
with high-fat diet 		Intestine length. inbred w/CC8 both 8-21 wks 2021
Beamer2 study archive Bone morphology and strength, insulin-like growth factor 1. QTL population f 16wks 2001
Benoist1 immune cell quantification Regulatory T cells (Treg), thymus, spleen. inbred   (33) m 5-6wks 2007
Berndt1 ventilator
with methacholine 		Airway resistance. Baseline vs. methacholine-challenged (several doses). inbred   (37) both 9-12wks 2010
Berndt2 plethysmography
with methacholine 		Lung, respiratory function. Baseline vs. methacholine-challenged (several doses). inbred   (29) both 9-12wks 2010
Berndt2 ventilator
with methacholine 		Lung, respiratory function. Anesthetized forced oscillation. Baseline vs. methacholine-challenged (several doses). inbred   (29) both 9-12wks 2010
Berndt4 histopathology Lung adenoma frequency and severity at 20mo. Tumor incidence, cancer, aging. inbred   (28) both 87wks 2011
Bopp1 health assessment
with Plasmodium berghei 		Susceptibility, Plasmodium berghei (malaria). Parasitemia in blood and distribution in brain, spleen, lungs, liver. inbred   (31) both 8-12wks 2010
Brockmann1 study archive Body, organ weights, litter size, abdominal fat, lipids, insulin, leptin. QTL population both 3-6wks 2009
Broman1 study archive Gut length. QTL population both 2006
Burke1 study archive Femur and vertebra morphology and strength. Monthly body weight 3 - 13 months. QTL population f 14-56wks 2012
CGDpheno3 tail cuff Heart rate and blood pressure. Conscious mice. CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 ECG Wave amplitudes and intervals. Conscious. CC diallel w/par   (62) both 8-16wks 2012
Chen1 immune cell quantification Natural killer T cells in peripheral blood, spleen, thymus. inbred   (38) both 8-10wks 2011
Chesler2 organ weights Heart, kidney weights. CC diallel w/par   (62) both 7-15wks 2011
Chesler3 organ weights Heart, brain, kidney, spleen, gonadal fat pads, testicle weights. CC pre w/par   (367) both 7-15wks 2011
Chesler3 organ dimensions Kidney length and volume. CC pre w/par   (367) both 7-15wks 2011
Cheverud1 organ weights
with high-fat diet 		Heart, liver, kidney, spleen weights after high-fat diet (17wks) vs. control. LGXSM w/par   (19) both 12-16wks 2004
Cowell1 in vitro assay
with Staphylococcus aureus 		Bacterial load after infection with Staphylococcus aureus. Kidney and peritoneal fluid. In vitro assay. inbred   (13) f 8wks 2012
Deschepper1 organ weights Heart, kidney, thymus, adrena weights. inbred   (13) both 10wks 2004
DiCurzio1 organ weights Adrenal weight. BXD w/par   (66) both 10wks 2010
DiCurzio1 histopathology Adrenal glands. BXD w/par   (66) both 10wks 2010
DiPetrillo3 study archive Blood pressure (tail cuff), heart rate, heart weight. QTL population both 8wks 2004
Dzur-Gejdosova1 study archive Sterility investigation. Sperm count, testes weight. QTL population m 9wks 2012
Eumorphia6 echocardiography Cardiovascular function and morphology. inbred   (4) both 12wks 2008
Eumorphia6 organ weights Cardiac ventricle weight. inbred   (4) both 12wks 2008
Eumorphia6 tail cuff Heart rate. inbred   (4) both 12wks 2008
Farmer1 study archive Colitis susceptibility, severity. Colon histopathology, body and spleen weight. QTL population both 6wks 2001
Feng1 study archive Blood pressure (tail cuff), kidney weight, body weight. QTL population m 8wks 2009
Ferris1 histopathology
with influenza A (H1N1) virus 		Lungs and airway 4 days after infection with influenza A (H1N1) virus. CC pre w/par   (163) f 8-16wks 2012
Gavras1 tail cuff
with sodium chloride 		Heart rate and blood pressure. Sodium chloride (1% solution for 2wks) vs. control. inbred   (11) both 9-12wks 2003
GMC03 observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol). inbred w/CC8   (8) both 8-10wks 2020
GMC12 echocardiography Cardiovascular function and morphology. inbred w/CC8   (8) both 14-15wks 2020
GMC13 ECG Heart rate and wave intervals. Conscious. inbred   (6) both 14-15wks 2020
GMC18 X-ray Lumbar vertebrae count. inbred w/CC8   (8) both 17-18wks 2020
GMC19 ventilator Lung, respiratory function. inbred w/CC8   (8) f 21-22wks 2020
GMC21 organ weights Heart, liver, spleen weights. inbred w/CC8   (8) both 20-21wks 2020
Graham1 immune cell quantification
with West Nile virus 		T cell populations in brain and spleen. CC RIX   (5) m 8-10wks 2015
Graham1 RNA expression profiling
with West Nile virus 		Viral load and expression of Ifnb1 and Ifit1 in brain, kidney and spleen. CC RIX   (5) m 8-10wks 2015
Graham2 in vitro assay
with SARS-CoV 		Lung viral load (log10). CC RIX   (117) f 8-10wks 2021
Graham3 immune cell quantification Baseline splenic T cell subsets. CC RIX   (104) m 8-10wks 2021
Graubert1 histopathology
with ENU 		Tumor growth frequency rates. ENU mutagen 100 mg/kg vs. control. inbred   (20) both 9wks; 12-64wks 2006
Gros1 in vitro assay
with Candida albicans 		Susceptibility to infection with Candida albicans. inbred   (36) f 8-12wks 2011
Guay-Woodford1 study archive Kidney morphology, renal cystic disease severity. QTL population f 2wks 2000
Gupta1 organ weights Kidney weight of newborns. inbred   (8) both postnatal 2011
Gupta1 organ dimensions Kidney morphology of newborns. Planar surface area. inbred   (8) both postnatal 2011
Gupta2 organ weights Kidney weight of newborns. BXH   (10) both postnatal 2011
Gupta2 organ dimensions Kidney morphology of newborns. Planar surface area. BXH   (10) both postnatal 2011
Hackstein1 immune cell quantification Respiratory dendritic cell subsets and lymphocyte populations. inbred   (5) m 7-11wks 2012
Hampton1 ECG Heart rate and wave intervals. Conscious. inbred   (17) both 9-12wks 2001
Handel1 organ weights Male reproductive organ weights. Seminal vesicles, testicles. inbred   (14) m 8-10wks 2010
Harrill1 organ weights
with isoniazid 		Body, liver, kidney weights. Isoniazid-treated vs. control. inbred   (34) f 8-10wks 2011
Harrill1 lipid profile
with isoniazid 		Cholesterol, triglycerides. Hepatic lipids. Isoniazid-treated vs. control. inbred   (34) f 8-10wks 2011
Harrill1 histopathology
with isoniazid 		Liver pathology scores. Isoniazid-treated vs. control. inbred   (34) f 8-10wks 2011
Harrill2 organ weights
with DB289 		Kidney and liver weights. DB289-treated vs. control. inbred   (34) f 6-8wks 2012
Haston1 health assessment
with radiation 		Survival rate and health assessment after exposure to radiation. Number of days without respiratory distress (max 26 wks). inbred   (26) both 15-36wks 2012
Haston1 bronchoalveolar lavage assessment
with radiation 		Bronchoalveolar cell differential after exposure to radiation (18 Gy). inbred   (26) both 15-36wks 2012
Haston1 histopathology
with radiation 		Post exposure to radiation. inbred   (26) both 15-36wks 2012
Hillebrands1 histopathology Kidney pathology at 20mo. inbred   (23) both 87wks 2014
HMDPpheno11 histopathology
with high-fat high-cholesterol diet 		Aortic lesion size after 16 wks on high-fat diet. HMDP hAPOE and hCETP transgenic   (103) both 23-25 wks 2015
Hunter1 histopathology Metastatic progression of mammary tumor and genetic background. MMTV PyVT transgenic   (28) f various 1998
Ishimori1 study archive
with high-fat diet 		Lipids, atherosclerosis lesions, parathyroid hormone after high-fat diet. QTL population f 20wks 2004
JaxCC1 ECG Heart rate and wave intervals. Conscious. CC   (18) both various 2018
JaxCC1 organ weights Heart weight. Raw and normalized to body weight. CC   (18) both various 2018
JaxKOMP-EAP observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol). KOMP both 8-18wks 2021
JaxKOMP-EAP ECG Heart rate and wave intervals. Conscious. KOMP both 8-18wks 2021
JaxKOMP-EAP X-ray Counts of vertebrae, ribs, digits, and other categorical parameters. KOMP both 8-18wks 2021
JaxKOMP-EAP organ weights Heart weight. Raw and normalized to body weight. KOMP both 8-18wks 2021
JaxKOMP-LAP observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol). KOMP both 66-81wks 2021
JaxKOMP-LAP ECG Heart rate and wave intervals. Conscious. KOMP both 66-81wks 2021
JaxKOMP-LAP organ weights Heart weight. Raw and normalized to body weight. KOMP both 66-81wks 2021
Jaxpheno2 organ weights Brain, heart, kidney, liver, spleen weights. inbred   (11) both 8, 16 wks 2006
Jaxpheno6 immune cell quantification White blood cell and immune cell differentials. inbred   (11) both 8, 16 wks 2006
Jaxpheno7 observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol). inbred   (6) m 10wks 2010
Jaxpheno8 echocardiography Cardiovascular function and morphology. inbred   (7) m 10-13wks 2010
Jaxwest1 ECG Heart rate and wave intervals. Conscious. inbred   (7) both 8-14wks 2003
Jaxwest1 tail cuff Heart rate and blood pressure. Conscious mice. inbred   (7) both 8-14wks 2003
Klaassen1 histopathology
with cadmium 		Cadmium-induced toxicity to liver, testis, trigeminal ganglia. inbred   (8) m 8wks 2001
Korstanje2 histopathology Kidney pathology. Aging study, 6mo, 12mo, 20mo. inbred   (29) m 52, 78, 104 wks 2013
Lake1 ECG Heart rate and wave intervals. Conscious. B6.A consomic w/par   (23) both 7-11wks 2005
Lake1 tail cuff Heart rate and blood pressure. Conscious mice. B6.A consomic w/par   (23) both 7-11wks 2005
Lake2 observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol). B6.A consomic w/par   (23) both 8wks 2005
Lazear1 organ weights Testis weight. CC   (12) m 13-21wks 2018
Lesage1 immune cell quantification Immunological cell variation. CC w/par   (76) both 5-8wks 2018
Lesage2 immune cell quantification total number of splenocytes, number of B cells in spleen, and percentage of splenocytes that are B cells CC w/par   (76) both 5-8wks 2024
Li1 study archive
with western diet 		Lipids, atherosclerosis lesion histopathology. High-fat, western-style diet. QTL population f 12wks 2008
Lionikas1 organ weights
with exercise 		Heart weight. Cardiac ventricle weight. Exercised (swim endurance training regimen) vs. control at weekly intervals for 5wks. inbred   (6) m 11-14wks 2012
Lyons1 study archive
with high-fat diet 		Lipids (plasma), liver weight, gallbladder and gallstone histopathology. QTL population m 16-18wks 2003
Lyons2 study archive
with high-fat diet 		Lipids (plasma), bile, liver weight, gallbladder and gallstone histopathology. QTL population m 16-18wks 2003
Lyons3 study archive
with high-fat diet 		Lipids, gallbladder and gallstone histopathology after high-fat diet. QTL population m 14-20wks 2004
Maeda1 study archive Atherosclerosis lesion histopathology, lesion sizes. QTL population both 18-20wks 2017
Mahler1 study archive Colitis susceptibility. Colon histopathology, spleen weight. QTL population both 6wks 2002
Maurer1 organ weights
with atenolol, isoproterenol 		Heart, atria, ventricle weights. Isoproterenol or atenolol vs. control. inbred   (23) m 10-12wks 2009
Maurer1 tail cuff
with atenolol, isoproterenol 		Heart rate and blood pressure. Conscious mice. Isoproterenol or atenolol vs. control. inbred   (23) m 10-12wks 2009
Maurer1 ECG
with atenolol, isoproterenol 		Heart rate and wave amplitudes and intervals. Unconscious. Isoproterenol or atenolol vs. control. inbred   (23) m 10-12wks 2009
Mills1 apoptosis assessment Aging study, 6mo, 12mo, 20mo. inbred   (30) both 26, 52, 87 wks 2008
Mrug1 study archive Kidney morphology. QTL population both 1-2wks 2005
Nadeau2 lipid profile
with high-fat high-sucrose diet 		Cholesterol, triglycerides. 16h fast, plasma. Hepatic triglycerides. B6.A consomic w/par   (24) m 5, 21 wks 2015
Nadeau2 organ weights
with high-fat high-sucrose diet 		Liver weight after 16wks of high-fat high-sucrose diet. 16h fast. B6.A consomic w/par   (24) m 5, 21 wks 2015
Nadeau3 lipid profile
with high-fat high-sucrose diet 		Cholesterol and triglycerides. Overnight fast, plasma. Hepatic triglycerides. inbred   (2) m 21 wks 2016
Nadeau3 organ weights
with high-fat high-sucrose diet 		Liver weight after 16 wks of high-fat high-sucrose diet. Overnight fast. inbred   (2) m 21 wks 2016
Odet1 organ weights Male reproductive organ weights. Testes, seminal vesicles, epididymis, vas deferens. inbred   (8) m 10-66wks 2015
Odet1 histopathology Male reproductive histopathology. Percent normal vs. abnormal sperm, seminiferous tubules. inbred   (8) m 10-66wks 2015
Paigen1 lipid profile
with high-fat diet 		Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen1 histopathology
with high-fat diet 		Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen1 organ dimensions
with high-fat diet 		Gallbladder volume after 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen1 organ weights
with high-fat diet 		Liver weight after 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen2 histopathology
with high-fat diet 		Aortic lesion size histopathology. Baseline vs. high-fat diet (17wks). inbred w/CC7   (43) both 7-9wks, 24-27wks 2002
Paigen3 lipid profile
with high-fat diet 		Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. obesity mutants   (8) both 15-19wks 2000
Paigen3 histopathology
with high-fat diet 		Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet obesity mutants   (8) both 15-19wks 2000
Paigen3 organ dimensions
with high-fat diet 		Gallbladder volume after 8wks on high-fat diet obesity mutants   (8) both 15-19wks 2000
Paigen3 organ weights
with high-fat diet 		Liver weight after 8wks on high-fat diet. obesity mutants   (8) both 15-19wks 2000
Payseur2 study archive Hybrid male sterility. Morphology, sperm count, histopathology. QTL population m 10-11wks 2018
Reed1 organ weights Heart, kidney weights. inbred   (28) m 8, 12 wks 2009
Reed2 organ weights Brain, heart, kidney, liver, pancreas, spleen weights. B6.129 and 129.B6 consomic w/par   (9) both 26wks 2015
Rodriguez1 study archive Spleen, liver murine cytomegalovirus study. QTL population both 8-12wks 2009
Rusyn5 organ weights
with high-fat diet and ethanol 		Liver weight after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 histopathology
with high-fat diet and ethanol 		Liver histopathology, injury after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 metabolite quantification
with high-fat diet and ethanol 		Homocysteine concentration after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 lipid profile
with high-fat diet and ethanol 		Hepatic triglycerides after 4wk regimen of ethanol and high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 RNA expression profiling
with high-fat diet and ethanol 		Liver gene expression after 4wk regimen of ethanol and high-fat diet. 24h fast. mRNA abundance relative to the control (high-fat only) group. inbred   (14) m 8-14wks 2011
Rusyn6 organ weights
with trichloroethylene 		Liver, kidney weights. Trichloroethylene-exposed vs. control. inbred   (7) m 6-7wks 2014
Rusyn6 drug and metabolite quantification
with trichloroethylene 		Trichloroethylene metabolite in blood, liver, kidney after trichloroethylene exposure. inbred   (7) m 6-7wks 2014
Rusyn6 RNA expression profiling
with trichloroethylene 		Trichloroethylene effect on mRNA gene expression in liver and kidney, relative to controls. inbred   (7) m 6-7wks 2014
Rusyn6 histopathology
with trichloroethylene 		Kidney histopathology evaluation after trichloroethylene exposure, relative to controls. inbred   (7) m 6-7wks 2014
Schonfeld1 lipid profile Cholesterol, triglycerides, free fatty acids, phospholipids. 5h fast, plasma. Hepatic triglycerides. inbred   (11) both 8-10wks 2005
Schonfeld1 organ weights Liver weight. inbred   (11) both 8-10wks 2005
Schoonjans1 biomarker quantification
with high-fat diet 		Bile acid levels in plasma, feces, and liver. BXD w/par   (36) m 8-29 wks 2022
Schoonjans1 organ weights
with high-fat diet 		Liver, spleen, kidney, fat pads, muscles, cecum. BXD w/par   (36) m 8-29 wks 2022
Schoonjans1 organ dimensions
with high-fat diet 		Small intestine length. BXD w/par   (36) m 8-29 wks 2022
Schughart4 in vitro assay
with influenza A (H3N2) virus 		Viral load in lungs after infection with influenza A (H3N2) virus. inbred w/CC8   (8) f 8-12wks 2016
Schulz1 ventilator Lung, respiratory function. inbred   (7) both 9-18wks 2000
Schwartz2 bronchoalveolar lavage assessment
with ovalbumin 		Lung inflammatory changes. Ovalbumin vs. control. inbred   (8) m 6-8wks 2001
Shorter4 organ weights Male reproductive organ weights. Testes, seminal vesicles, epididymis + vas deferens. CC   (12) m 15-33wks 2020
Shorter5 organ weights Male reproductive organ weights. Testes, seminal vesicles, epididymis + vas deferens. CC RIX   (28) m 7-44wks 2020
Shorter8 organ weights Male reproductive organ weights. Testes, seminal vesicles, epididymis + vas deferens. DO population m 12-15wks 2020
Solberg1 study archive Open field test, forced swim test, defensive burying task. QTL population both 11-17wks 2004
Su2 study archive
with high-fat diet 		Lipids (plasma). Cholesterol, triglycerides, aortic lesions, body mass index. QTL population f 14wks 2009
Sugiyama1 tail cuff Heart rate and blood pressure. Conscious mice. inbred   (25) m 10wks 2007
Sugiyama3 study archive Blood pressure (tail cuff), heart weight, body weight. QTL population m 10wks 2002
Sunde1 RNA expression profiling
with selenium 		Selenium regulation of selenoprotein enzyme activity and transcripts. inbred w/CC8   (8) m 3-14wks 2018
Svenson1 tail cuff Heart rate and blood pressure. Conscious mice. inbred   (14) both 9wks 2004
Threadgill1 metabolic panel
with acetaminophen 		Blood urea nitrogen, alanine transaminase, aspartate transaminase (serum), liver enzyme homeostasis. Acetaminophen (several doses) vs. control, several timepoints post-Rx. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 histopathology
with acetaminophen 		Liver histopathology, necrosis after acetaminophen vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 metabolite quantification
with acetaminophen 		Liver protein homeostasis. Acetaminophen vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 biomarker quantification
with acetaminophen 		Liver cytochrome isoforms. Acetaminophen vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 organ weights
with acetaminophen 		Liver weight after acetaminophen (several doses) vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill2 metabolite quantification
with acetaminophen 		Glutathione. inbred   (5) m 6-8wks 2005
Threadgill2 histopathology
with acetaminophen 		Liver histopathology, necrosis, injury after acetaminophen vs. control. 18h fast. inbred   (5) m 6-8wks 2005
Vulpe1 mineral quantification Liver mineral levels. Iron, copper, zinc. Iron homeostasis. inbred   (18) both 8wks 2010
Wang1 study archive
with high-fat diet 		Lipids (plasma). Cholesterol, inducibility, triglycerides, atherosclerosis lesions. QTL population f 10-23wks 2003
Williams1 immune cell quantification CD4 T cells, various populations. inbred   (5) f 8wks 2012
Wiltshire4 immune cell quantification
with BEZ235, doxorubicin, idarubicin, selumetinib 		In vitro study of 4 cancer chemotherapies (BEZ235, doxorubicin, idarubicin, selumetinib) vs. control. Effect on immune cells. Normalized data. inbred w/CC7   (36) m 10wks 2015
Wittenburg1 study archive
with high-fat diet 		Liver weight, gallbladder and gallstone histopathology. QTL population both 18-20wks 2002
Wittenburg2 study archive
with high-fat diet 		Lipids (plasma), liver weight, gallbladder and gallstone histopathology. QTL population both 6-16wks 2003
Wittenburg3 study archive
with high-fat diet 		Lipids (plasma), liver weight, gallbladder and gallstone histopathology. QTL population both 2005
Xenakis2 metabolite quantification
with arsenic 		iAs quantification in urine and liver, at 24 and 26 wks after iAs exposure. IAs speciation evaluated specifically monomethyl-arsenic acid (MMA) and dimethyl-arsenic acid (DMA) DO population m 4-34 wks 2022
Xing1 ECG Heart rate and wave intervals. Conscious. Aging study, 6mo, 12mo, 20mo. inbred   (29) both 26, 52, 87 wks 2008
Yi1 study archive Body weight (several timepoints) and liver weight. QTL population both 2-12wks 2007
Zhang1 study archive
with western diet 		Atherosclerosis and glucose homeostasis. Lesions, lipids, glucose, insulin. High-fat, western-style diet. QTL population f <6-18wks 2012