Lake2: SHIRPA assessment, C57BL/6J-Chr#A/J/NaJ mouse chromosome substitution panel (2005)

Lake J, Donahue L, Davisson MT

       
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Participants Jeffrey Lake       The Jackson Laboratory Bar Harbor, ME
Leah Rae Donahue       The Jackson Laboratory Bar Harbor, ME
Muriel T Davisson       The Jackson Laboratory Bar Harbor, ME
ContactJeffrey Lake     jpl@jax.org
Part of a series: • physiology   see Lake1
• SHIRPA   (this project) Lake2
• behavior   see Lake3
Project type Phenotype strain survey data set
MPD identifiersLake2     MPD:217
Data changelog No updates/corrections.       Initial release date: 10/2007.
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Animals were evaluated using the SHIRPA behavioral and neuromuscular assessment. For SHIRPA scoring table see the project protocol.

Summary of procedures that were conducted
• observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol).
Mice: B6.A consomic w/par   23 strains   ♀♂   age 8wks   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Lake2 21701 observation (SHIRPA) (none) spontaneous activity level in view-jar (score 0-3)   [score]  activity B6.A consomic w/par 23 both 8wks N=8
    Lake2 21702 observation (SHIRPA) (none) constant trembling in view-jar (score 0-2)   [score]  tremor B6.A consomic w/par 23 both 8wks N=8
    Lake2 21703 observation (SHIRPA) (none) short sporadic twitches in view-jar (score 0-2)   [score]  twitch B6.A consomic w/par 23 both 8wks N=8
    Lake2 21704 observation (SHIRPA) (none) number of fecal boli in view-jar   [n]  defecation_jar B6.A consomic w/par 23 both 8wks N=8
    Lake2 21705 observation (SHIRPA) (none) number of urine puddles in view-jar   [n]  urination_jar B6.A consomic w/par 23 both 8wks N=8
    Lake2 21706 observation (SHIRPA) (none) transfer (view-jar to arena) provoked response (score 0-4)   [score]  transfer_arousal B6.A consomic w/par 23 both 8wks N=8
    Lake2 21707 observation (SHIRPA) (none) fear assessment during transfer to arena (score 0-1)   [score]  freeze B6.A consomic w/par 23 both 8wks N=8
    Lake2 21708 observation (SHIRPA) (none) number of fecal boli in arena   [n]  defecation_arena B6.A consomic w/par 23 both 8wks N=8
    Lake2 21709 observation (SHIRPA) (none) number of urine puddles in arena   [n]  urination_arena B6.A consomic w/par 23 both 8wks N=8
    Lake2 21710 observation (SHIRPA) (none) degree of pelvis elevation while in motion in arena (score 0-3)   [score]  pelvic_elevation B6.A consomic w/par 23 both 8wks N=8
    Lake2 21711 observation (SHIRPA) (none) degree of tail elevation while in forward motion in arena (score 0-4)   [score]  tail_elevation B6.A consomic w/par 23 both 8wks N=8
    Lake2 21712 observation (SHIRPA) (none) color evaluation of plantar surface and forelimb digits during supine restraint (score 0-2)   [score]  skin_color B6.A consomic w/par 23 both 8wks N=8
    Lake2 21713 observation (SHIRPA) (none) gait assessment within the arena (score 0-3)   [score]  gait B6.A consomic w/par 23 both 8wks N=8
    Lake2 21714 observation (SHIRPA) (none) postural response to being held in different positions above arena (score 0-4)   [score]  positional_passivity B6.A consomic w/par 23 both 8wks N=8
    Lake2 21715 observation (SHIRPA) (none) body tone assessed by thumb and index finger compression while on horizontal wire-grid (score 0-2)   [score]  body_tone B6.A consomic w/par 23 both 8wks N=8
    Lake2 21716 observation (SHIRPA) (none) resistance to gentle finger-tip pressure of the hind paws during supine restraint (score 0-4)   [score]  limb_tone B6.A consomic w/par 23 both 8wks N=8
    Lake2 21717 observation (SHIRPA) (none) abdominal tone via palpation during supine restraint (score 0-2)   [score]  abdominal_tone B6.A consomic w/par 23 both 8wks N=8
    Lake2 21718 observation (SHIRPA) (none) response to rotation while held in extension by the tail with forelimbs gripping (wire maneuver) (score 0-4)   [score]  hindlimb_rotation B6.A consomic w/par 23 both 8wks N=8
    Lake2 21722 observation (SHIRPA) (none) characteristic movement in response to supine recumbent position (score 0-3)   [score]  righting B6.A consomic w/par 23 both 8wks N=8
    Lake2 21723 observation (SHIRPA) (none) eyelid (palpebral) fissure presentation in arena (score 0-2)   [score]  palpebral_fissure B6.A consomic w/par 23 both 8wks N=8
    Lake2 21724 observation (SHIRPA) (none) status of hair coat in arena (score 0-1)   [score]  piloerection B6.A consomic w/par 23 both 8wks N=8
    Lake2 21725 observation (SHIRPA) (none) response to airpuff from behind in arena (score 0-4)   [score]  startle_response B6.A consomic w/par 23 both 8wks N=8
    Lake2 21726 observation (SHIRPA) (none) trunk curl during tail suspension (score 0-1)   [score]  trunk_curl B6.A consomic w/par 23 both 8wks N=8
    Lake2 21727 observation (SHIRPA) (none) hindlimb grasp during tail suspension (score 0-1)   [score]  limb_grasp B6.A consomic w/par 23 both 8wks N=8
    Lake2 21728 observation (SHIRPA) (none) presence of lacrimal fluid (tears) around eyes during supine restraint (score 0-1)   [score]  lacrimation B6.A consomic w/par 23 both 8wks N=8
    Lake2 21729 observation (SHIRPA) (none) salivation response when provoked with probe between teeth during supine restraint (score 0-2)   [score]  salivation B6.A consomic w/par 23 both 8wks N=8
    Lake2 21730 observation (SHIRPA) (none) touch provoked withdrawal (escape) reflex in arena (score 0-3)   [score]  touch_escape B6.A consomic w/par 23 both 8wks N=8
    Lake2 21731 observation (SHIRPA) (none) forelimb extension towards horizontal wire-grid when lowered by tail (score 0-3)   [score]  visual_placing B6.A consomic w/par 23 both 8wks N=8
    Lake2 21732 observation (SHIRPA) (none) ear pinna withdrawal response to sensory stimulation on horizontal wire-grid (score 0-2)   [score]  pinna_reflex B6.A consomic w/par 23 both 8wks N=8
    Lake2 21733 observation (SHIRPA) (none) eye-blink response to corneal stimulation on horizontal wire-grid (score 0-2)   [score]  corneal_reflex B6.A consomic w/par 23 both 8wks N=8
    Lake2 21734 observation (SHIRPA) (none) withdrawal refex following toe pinch of hind foot mid-digit on horizontal wire-grid (score 0-4)   [score]  withdrawal_reflex B6.A consomic w/par 23 both 8wks N=8
    Lake2 21735 observation (SHIRPA) (none) extension of opposite foot after toe pinch on horizontal wire-grid (score 0-1)   [score]  cross_reflex B6.A consomic w/par 23 both 8wks N=8
    Lake2 21736 observation (SHIRPA) (none) incidence of provoked biting during supine restraint (score 0-1)   [score]  biting B6.A consomic w/par 23 both 8wks N=8
    Lake2 21737 observation (SHIRPA) (none) assessment of irritability during supine restraint (score 0-1)   [score]  irritability B6.A consomic w/par 23 both 8wks N=8
    Lake2 21738 observation (SHIRPA) (none) assessment of aggression during supine restraint (score 0-1)   [score]  aggression B6.A consomic w/par 23 both 8wks N=8
    Lake2 21739 observation (SHIRPA) (none) assessment of vocalization during supine restraint (score 0-1)   [score]  vocal B6.A consomic w/par 23 both 8wks N=8
    Lake2 21740 observation (SHIRPA) (none) characteristic movement with head facing upward on vertical wire grid (score 0-4)   [score]  catalepsy B6.A consomic w/par 23 both 8wks N=8
    Lake2 21741 observation (SHIRPA) (none) characteristic movement with head facing downward on vertical wire grid (score 0-4)   [score]  neg_geo B6.A consomic w/par 23 both 8wks N=8
    Lake2 21742 observation (SHIRPA) (none) body position in view-jar (score 0-5)   [score]  body_position B6.A consomic w/par 23 both 8wks N=8
    Lake2 21743 observation (SHIRPA) (none) hindlimb splay evaluation via dorso-ventral view in arena (score 0-2)   [score]  hindlimb_dorsal B6.A consomic w/par 23 both 8wks N=8
    Lake2 21744 observation (SHIRPA) (none) distance between ankle joints during tail suspension (score 0-2)   [score]  hindlimb_susp B6.A consomic w/par 23 both 8wks N=8
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