DiPetrillo3: Blood pressure in F2 progeny from a C3H x SWR intercross (2004)

DiPetrillo K, Tsaih SW, Sheehan S, Johns C, Kelmenson P, Gavras H, Churchill GA, Paigen B. Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice. Physiol Genomics. 2004 Apr 13;17(2):215-20.   PubMed 14996992  


       
This cross is designed to identify the genetic loci that control systolic blood pressure in intercross: C3H/HeJ X SWR/J (C3HxSWR). Total of 217 F2 mice with 103 SSLP markers were used in the final QTL analysis. For detailed protocols see DiPetrillo et al 2004.

Note on studied population: C3H x SWR intercross F2 progeny

Procedures conducted:
• study archive  Blood pressure (tail cuff), heart rate, heart weight.

DiPetrillo3 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.
Investigators Keith DiPetrillo       Novartis,  East Hanover, NJ
Participants Tsaih SW, Sheehan S, Johns C, Kelmenson P, Gavras H, Churchill GA, Paigen B
ContactKeith DiPetrillo     keith.dipetrillo@novartis.com
Affiliated CenterQTL Archive
AcknowledgementsThis work was supported National Heart, Lung, and Blood Institute Program for Genomic Applications Grants HL-66611, by the Specialized Centers of Research (SCOR) Program Grant HL-55001, and by National Institutes of Health Cancer Core Grant CA-34196 to The Jackson Laboratory.
Project type QTL Archive data set
MPD identifiersDiPetrillo3     MPD:139
Data changelog No updates/corrections.       Initial release date: 10/2009.
QTL data set parameters:
Progenitor strains C3H/HeJ     SWR/J    
Cross direction notation(C3HxSWR) F1 x (C3HxSWR) F1; (SWRxC3H) F1 x (SWRxC3H) F1
Cross typeF2 reciprocal intercross
Population size 102 ♀     115 ♂
Age8wks


Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.

Associated genomic features
MGI-curated QTL / genomic features that have been associated with this data set:
Bpq8   Bpq9  


Project / data set:   DiPetrillo3     a.k.a. Dipetrillo_2004
Excel file:   Data_Description_C3HxSWR_DiPetrillo2004.xlsx
CSV file:   DiPetrillo2004_C3HxSWR_B37_Data.csv
Readme / text file:   ._readme.txt
Readme / text file:   readme_DiPetrillo2004.txt
QC plots, figures, etc.:   QCReport_DiPetrillo2004.pdf