Jaxpheno7: Neuromuscular and behavioral testing in males of 6 inbred strains of mice (2010)

Jackson Laboratory   With: Denegre J, Yang Y, Nicholson A, Davis C, Ryan J, McFarland H

       
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Institutional authorship Jackson Laboratory
Participants Denegre J, Yang Y, Nicholson A, Davis C, Ryan J, McFarland H
ContactJames Denegre     james.denegre@jax.org
AffiliationJAX Phenotyping Center
Project type Phenotype strain survey data set
MPD identifiersJaxpheno7     MPD:349
Data changelog No updates/corrections.       Initial release date: 08/2010.
Formatted citation
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Animals were evaluated in these areas: SHIRPA, rotarod, grip strength.

Summary of procedures that were conducted
• observation (SHIRPA) Behavior, and neurosensory responses (SHIRPA protocol).
• grip strength Peak tension.
• rotarod Latency to fall from accelerating rotarod.
Mice: inbred   6 strains   ♂   age 10wks   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Jaxpheno7 34901 observation (SHIRPA) (none) body position in view-jar (score 0-5)   [score]  body_position inbred 6 m 10wks N=9
    Jaxpheno7 34902 observation (SHIRPA) (none) degree of pelvis elevation while in motion in arena (score 0-3)   [score]  pelvic_elevation inbred 6 m 10wks N=9
    Jaxpheno7 34903 observation (SHIRPA) (none) degree of tail elevation while in forward motion in arena (score 0-4)   [score]  tail_elevation inbred 6 m 10wks N=9
    Jaxpheno7 34904 observation (SHIRPA) (none) color evaluation of plantar surface and forelimb digits during supine restraint (score 0-2)   [score]  skin_color inbred 6 m 10wks N=9
    Jaxpheno7 34905 observation (SHIRPA) (none) hindlimb splay evaluation via dorso-ventral view in arena (score 0-2)   [score]  hindlimb_dorsal inbred 6 m 10wks N=9
    Jaxpheno7 34906 observation (SHIRPA) (none) hindlimb splay evaluation via vertical view in arena (score 0-2)   [score]  limb_pattern inbred 6 m 10wks N=9
    Jaxpheno7 34907 observation (SHIRPA) (none) transfer (view-jar to arena) provoked response (score 0-4)   [score]  transfer_arousal inbred 6 m 10wks N=9
    Jaxpheno7 34908 observation (SHIRPA) (none) fear assessment during transfer to arena (score 0-1)   [score]  freeze inbred 6 m 10wks N=9
    Jaxpheno7 34909 observation (SHIRPA) (none) spontaneous activity level in view-jar (score 0-3)   [score]  activity inbred 6 m 10wks N=9
    Jaxpheno7 34910 observation (SHIRPA) (none) constant trembling in view-jar (score 0-2)   [score]  tremor inbred 6 m 10wks N=9
    Jaxpheno7 34911 observation (SHIRPA) (none) short sporadic twitches in view-jar (score 0-2)   [score]  twitch inbred 6 m 10wks N=9
    Jaxpheno7 34912 observation (SHIRPA) (none) number of fecal boli in view-jar   [n]  defecation_jar inbred 6 m 10wks N=9
    Jaxpheno7 34913 observation (SHIRPA) (none) number of urine puddles in view-jar   [n]  urination_jar inbred 6 m 10wks N=9
    Jaxpheno7 34914 observation (SHIRPA) (none) number of fecal boli in arena   [n]  defecation_arena inbred 6 m 10wks N=9
    Jaxpheno7 34915 observation (SHIRPA) (none) number of urine puddles in arena   [n]  urination_arena inbred 6 m 10wks N=9
    Jaxpheno7 34916 observation (SHIRPA) (none) incidence of provoked biting during supine restraint (score 0-1)   [score]  biting inbred 6 m 10wks N=9
    Jaxpheno7 34917 observation (SHIRPA) (none) assessment of irritability during supine restraint (score 0-1)   [score]  irritability inbred 6 m 10wks N=9
    Jaxpheno7 34918 observation (SHIRPA) (none) assessment of aggression during supine restraint (score 0-1)   [score]  aggression inbred 6 m 10wks N=9
    Jaxpheno7 34919 observation (SHIRPA) (none) assessment of vocalization during supine restraint (score 0-1)   [score]  vocal inbred 6 m 10wks N=9
    Jaxpheno7 34920 observation (SHIRPA) (none) response to object placed near head (score 0-4)   [score]  finger_approach inbred 6 m 10wks N=9
    Jaxpheno7 34921 observation (SHIRPA) (none) eyelid (palpebral) fissure presentation in arena (score 0-2)   [score]  palpebral_fissure inbred 6 m 10wks N=9
    Jaxpheno7 34922 observation (SHIRPA) (none) status of hair coat in arena (score 0-1)   [score]  piloerection inbred 6 m 10wks N=9
    Jaxpheno7 34923 observation (SHIRPA) (none) response to airpuff from behind in arena (score 0-4)   [score]  startle_response inbred 6 m 10wks N=9
    Jaxpheno7 34924 observation (SHIRPA) (none) trunk curl during tail suspension (score 0-1)   [score]  trunk_curl inbred 6 m 10wks N=9
    Jaxpheno7 34925 observation (SHIRPA) (none) hindlimb grasp during tail suspension (score 0-1)   [score]  limb_grasping inbred 6 m 10wks N=9
    Jaxpheno7 34926 observation (SHIRPA) (none) presence of lacrimal fluid (tears) around eyes during supine restraint (score 0-1)   [score]  lacrimation inbred 6 m 10wks N=9
    Jaxpheno7 34927 observation (SHIRPA) (none) salivation response when provoked with probe between teeth during supine restraint (score 0-2)   [score]  salivation inbred 6 m 10wks N=9
    Jaxpheno7 34928 observation (SHIRPA) (none) gait assessment within the arena (score 0-3)   [score]  gait inbred 6 m 10wks N=9
    Jaxpheno7 34929 observation (SHIRPA) (none) postural response to being held in different positions above arena (score 0-4)   [score]  positional_passivity inbred 6 m 10wks N=9
    Jaxpheno7 34930 observation (SHIRPA) (none) body tone assessed by thumb and index finger compression while on horizontal wire-grid (score 0-2)   [score]  body_tone inbred 6 m 10wks N=9
    Jaxpheno7 34931 observation (SHIRPA) (none) resistance to gentle finger-tip pressure of the hind paws during supine restraint (score 0-4)   [score]  limb_tone inbred 6 m 10wks N=9
    Jaxpheno7 34932 observation (SHIRPA) (none) abdominal tone via palpation during supine restraint (score 0-2)   [score]  abdominal_tone inbred 6 m 10wks N=9
    Jaxpheno7 34933 observation (SHIRPA) (none) touch provoked withdrawal (escape) reflex in arena (score 0-3)   [score]  touch_escape inbred 6 m 10wks N=9
    Jaxpheno7 34934 observation (SHIRPA) (none) forelimb extension towards horizontal wire-grid when lowered by tail (score 0-3)   [score]  visual_placing inbred 6 m 10wks N=9
    Jaxpheno7 34935 observation (SHIRPA) (none) ear pinna withdrawal response to sensory stimulation on horizontal wire-grid (score 0-2)   [score]  pinna_reflex inbred 6 m 10wks N=9
    Jaxpheno7 34936 observation (SHIRPA) (none) eye-blink response to corneal stimulation on horizontal wire-grid (score 0-2)   [score]  corneal_reflex inbred 6 m 10wks N=9
    Jaxpheno7 34937 observation (SHIRPA) (none) withdrawal refex following toe pinch of hind foot mid-digit on horizontal wire-grid (score 0-4)   [score]  withdrawal_reflex inbred 6 m 10wks N=9
    Jaxpheno7 34938 observation (SHIRPA) (none) extension of opposite foot after toe pinch on horizontal wire-grid (score 0-1)   [score]  cross_extensor inbred 6 m 10wks N=9
    Jaxpheno7 34939 observation (SHIRPA) (none) ability of forelimbs and hindlimbs to grasp wire-screen held in horizontal rotation (score 0-4)   [score]  wire_grip inbred 6 m 10wks N=9
    Jaxpheno7 34940 observation (SHIRPA) (none) characteristic movement in response to supine recumbent position (score 0-3)   [score]  righting inbred 6 m 10wks N=9
    Jaxpheno7 34941 observation (SHIRPA) (none) characteristic movement with head facing upward on vertical wire grid (score 0-4)   [score]  catalepsy inbred 6 m 10wks N=9
    Jaxpheno7 34942 observation (SHIRPA) (none) characteristic movement with head facing downward on vertical wire grid (score 0-4)   [score]  neg_geo inbred 6 m 10wks N=9
    Jaxpheno7 34943 rotarod (none) latency to fall from stationary rotarod during habituation period   [s]     trial1    trial2    trial3    average inbred 6 m 10wks N=7
    Jaxpheno7 34947 rotarod (none) latency to fall from rotarod at constant 4 rpm   [s]     trial1    trial2    trial3    average inbred 6 m 10wks N=7
    Jaxpheno7 34951 rotarod (none) latency to fall from accelerating (60 rpm/min) rotarod   [s]     trial1    trial2    trial3    average inbred 6 m 10wks N=9
    Jaxpheno7 34955 rotarod (none) peak acceleration (0.1 rpm/s) on the rotarod prior to fall   [s]     trial1    trial2    trial3    average inbred 6 m 10wks N=9
    Jaxpheno7 34959 grip strength (none) grip strength, peak tension   [g]     trial1    trial2    trial3 inbred 6 m 10wks N=9
    Jaxpheno7 34962 grip strength (none) grip strength mean peak tension over 3 trials   [g]  mean_grip inbred 6 m 10wks N=9
    Jaxpheno7 34963 grip strength (none) grip strength maximum peak tension over 3 trials   [g]  max_grip inbred 6 m 10wks N=9
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