MPD: Data set: Hackstein1

Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012 Oct 15;13:94. doi: 10.1186/1465-9921-13-94. PubMed 23066782 FullText

Procedures conducted:

• immune cell quantification

Respiratory dendritic cell subsets and lymphocyte populations.

Hackstein1 downloads
• Download Hackstein1 project data set animal data, as uploaded
• Download Hackstein1 animal data matrix with factor-related expansion applied as necessary
• Download Hackstein1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Hackstein1 measures:

MA:0000415 lung
MP:0000217 abnormal leukocyte cell number
MP:0002458 abnormal B cell number
MP:0002602 abnormal eosinophil cell number
MP:0006387 abnormal T cell number
MP:0008043 abnormal NK cell number
MP:0008073 abnormal CD4-positive, alpha beta T cell number
MP:0008077 abnormal CD8-positive, alpha-beta T cell number
MP:0008125 abnormal dendritic cell number
MP:0012440 abnormal neutrophil cell number
MP:0012773 abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number
MP:0020202 abnormal macrophage cell number
VT:0000217 leukocyte quantity
VT:0000222 neutrophil quantity
VT:0001830 effector T cell quantity
VT:0002458 B cell quantity
VT:0002602 eosinophil quantity
VT:0005425 macrophage quantity
VT:0008043 natural killer cell quantity
VT:0008073 CD4-positive T cell quantity
VT:0008077 CD8-positive T cell quantity
VT:0008125 dendritic cell quantity
VT:0008345 gamma-delta T cell quantity
VT:0008397 CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology trait

Investigators	Holger Hackstein Justus-Liebig University, Giessen GERMANY
Participants	Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N
Contact	Holger Hackstein Holger.Hackstein@immunologie.med.uni-giessen.de
Acknowledgements	Funding provided by German Science Foundation; University Giessen and Marburg Lung Center
Project type	Phenotype strain survey data set
MPD identifiers	Hackstein1 MPD:491
Data changelog	No updates/corrections. Initial release date: 10/2013.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Hackstein1:1	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage total leukocyte count (x 10³) [n] BAL 49101	inbred	5	m	7-11wks	N=5

Hackstein1:2	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage macrophages (percentage of leukocytes) [%] BAL_MAC 49102	inbred	5	m	7-11wks	N=5

Hackstein1:3	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage dendritic cells (percentage of CD45+ cells) [%] DC 49103	inbred	5	m	7-11wks	N=9

Hackstein1:4	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage plasmacytoid dendritic cells (percentage of CD45+ cells) [%] DC_plasmacytoid 49104	inbred	5	m	7-11wks	N=9

Hackstein1:5	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage monocytic dendritic cells (percentage of CD45+ cells) [%] DC_monocytic 49105	inbred	5	m	7-11wks	N=9

Hackstein1:6	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD103+ dendritic cells (percentage of CD45+ cells) [%] DC_103 49106	inbred	5	m	7-11wks	N=9

Hackstein1:7	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD11b^hi MHC^hi dendritic cells (percentage of CD45+ cells) [%] DC_11b 49107	inbred	5	m	7-11wks	N=9

Hackstein1:8	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage Siglec F+ F4/80+ macrophages (percentage of CD45+ cells) [%] MAC 49108	inbred	5	m	7-11wks	N=9

Hackstein1:9	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage neutrophils (percentage of CD45+ cells) [%] NEUT 49109	inbred	5	m	7-11wks	N=9

Hackstein1:10	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage eosinophils (percentage of CD45+ cells) [%] EOS 49110	inbred	5	m	7-11wks	N=9

Hackstein1:11	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage Lin^neg CD90+ innate cells (percentage of CD45+ cells) [%] Lin_neg_90_plus 49111	inbred	5	m	7-11wks	N=6

Hackstein1:12	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage Lin^neg CD90^- innate cells (percentage of CD45+ cells) [%] Lin_neg_90_neg 49112	inbred	5	m	7-11wks	N=6

Hackstein1:13	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD19+ B cells (percentage of CD45+ cells) [%] B_cells 49113	inbred	5	m	7-11wks	N=8

Hackstein1:14	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ T cells (percentage of CD45+ cells) [%] T_CD3 49114	inbred	5	m	7-11wks	N=9

Hackstein1:15	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD8+ T cells (percentage of CD45+ cells) [%] T_CD8 49115	inbred	5	m	7-11wks	N=9

Hackstein1:16	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ T cells (percentage of CD45+ cells) [%] T_CD4 49116	inbred	5	m	7-11wks	N=9

Hackstein1:17	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25+ T cells (percentage of CD45+ cells) [%] T_CD4_25 49117	inbred	5	m	7-11wks	N=8

Hackstein1:18	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25^hi Treg cells (percentage of CD45+ cells) [%] T_CD4_25hi 49118	inbred	5	m	7-11wks	N=5

Hackstein1:19	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25^hi Foxp3+ Treg cells (percentage of CD45+ cells) [%] T_CD4_foxp3 49119	inbred	5	m	7-11wks	N=5

Hackstein1:20	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25^hi Foxp3+ CD39+ Treg cells (percentage of CD45+ cells) [%] T_CD4_39 49120	inbred	5	m	7-11wks	N=5

Hackstein1:21	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ gamma-delta T cells (percentage of CD45+ cells) [%] T_gd 49121	inbred	5	m	7-11wks	N=9

Hackstein1:22	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD49+ natural killer (NK) cells (percentage of CD45+ cells) [%] NK 49122	inbred	5	m	7-11wks	N=9

Hackstein1: Respiratory dendritic cell subsets and lymphocyte populations in 5 inbred strains of mice (2012)