Jaxwest1: Multi-system analysis of physiology on 7 inbred strains of mice (2003)

Jackson Laboratory   With: Yang Y, Kitten A, Griffey S, Chang F, Dixon K, Browne C, Clary D

         
Jaxwest1 downloads
• Download Jaxwest1 project data set     one row per animal, one column per trait
• Download Jaxwest1 strain means, SD, N, etc.     one row per strain/sex/measure
• Jaxwest1 supplementary data
Ontology terms mapped to Jaxwest1 measures:
    MA:0000009   adipose tissue
    MA:0000010   cardiovascular system
    MA:0000072   heart
    MA:0000615   forelimb muscle
    MA:0001459   bone
    MP:0000230   abnormal systemic arterial blood pressure
    MP:0001259   abnormal body weight
    MP:0001515   abnormal grip strength
    MP:0001629   abnormal heart rate
    MP:0002089   abnormal postnatal growth/weight/body size
    MP:0002733   abnormal thermal nociception
    MP:0003897   abnormal ST segment
    MP:0003898   abnormal QRS complex
    MP:0003899   abnormal QT interval
    MP:0003901   abnormal PR interval
    MP:0003959   abnormal lean body mass
    MP:0005452   abnormal adipose tissue amount
    MP:0005457   abnormal percent body fat/body weight
    MP:0010119   abnormal bone mineral density
    MP:0010122   abnormal bone mineral content
    MP:0010504   abnormal RR interval
    MP:0010695   abnormal blood pressure regulation
    MP:0011918   abnormal PQ interval
    MP:0012321   abnormal total tissue mass
    VT:0000183   blood pressure trait
    VT:0000231   heart excitatory physiology trait
    VT:0001259   body mass
    VT:0001970   pain threshold
    VT:0002733   thermal nociception trait
    VT:0005007   bone mineral mass
    VT:0005452   adipose amount
    VT:0010080   skeletal muscle physiology trait
    VT:0010482   body fat mass
    VT:0010483   body lean mass
    VT:2000009   heart pumping trait
Institutional authorship Jackson Laboratory     Lab web site
Participants Yang Y, Kitten A, Griffey S, Chang F, Dixon K, Browne C, Clary D
ContactYan Yang     yan.yang@jax.org     Lab web site
AffiliationJAX In Vivo Services
Project type Phenotype strain survey data set
MPD identifiersJaxwest1     MPD:151
Data changelog 3 updates/corrections.       Initial release date: 06/2004.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Animals were assessed in these areas: body and bone composition, cardiovascular, grip strength, pain sensitivity using DXA system, conscious non-invasive ECG and blood pressure, cold/hot plate analgesia, and grip strength.

Summary of procedures that were conducted
• body weight
• DXA Body mass, fat mass, lean mass, bone mineral density and content (whole body, femur, spine).
• ECG Heart rate and wave intervals. Conscious.
• tail cuff Heart rate and blood pressure. Conscious mice.
• grip strength Peak tension.
• nociception assay Hot plate.
Mice: inbred   7 strains   ♀♂   age 8-14wks   1 cohort