Jaxwest1: Multi-system analysis of physiology on 7 inbred strains of mice (2003)

Jackson Laboratory   Yan Yang   With: Yang Y, Kitten A, Griffey S, Chang F, Dixon K, Browne C, Clary D

         
Jaxwest1 downloads
• Download Jaxwest1 project data set     animal data, as uploaded
• Download Jaxwest1 animal data matrix     with factor-related expansion applied as necessary
• Download Jaxwest1 strain means, SD, N, etc.     one row per strain/sex/measure
• Jaxwest1 supplementary data
Ontology terms mapped to Jaxwest1 measures:
    MA:0000009   adipose tissue
    MA:0000010   cardiovascular system
    MA:0000072   heart
    MA:0000615   forelimb muscle
    MA:0001459   bone
    MP:0000230   abnormal systemic arterial blood pressure
    MP:0001259   abnormal body weight
    MP:0001515   abnormal grip strength
    MP:0001629   abnormal heart rate
    MP:0002089   abnormal postnatal growth/weight/body size
    MP:0002733   abnormal thermal nociception
    MP:0003897   abnormal ST segment
    MP:0003898   abnormal QRS complex
    MP:0003899   abnormal QT interval
    MP:0003901   abnormal PR interval
    MP:0003959   abnormal lean body mass
    MP:0005452   abnormal adipose tissue amount
    MP:0005457   abnormal percent body fat/body weight
    MP:0010119   abnormal bone mineral density
    MP:0010122   abnormal bone mineral content
    MP:0010504   abnormal RR interval
    MP:0010695   abnormal blood pressure regulation
    MP:0011918   abnormal PQ interval
    MP:0012321   abnormal total tissue mass
    VT:0000183   blood pressure trait
    VT:0000231   heart excitatory physiology trait
    VT:0001259   body mass
    VT:0001970   pain threshold
    VT:0002733   thermal nociception trait
    VT:0005007   bone mineral mass
    VT:0005452   adipose amount
    VT:0010080   skeletal muscle physiology trait
    VT:0010482   body fat mass
    VT:0010483   body lean mass
    VT:2000009   heart pumping trait
Institutional authorship Jackson Laboratory     Lab web site
Investigators Yan Yang       The Jackson Laboratory,  Bar Harbor, ME
Participants Yang Y, Kitten A, Griffey S, Chang F, Dixon K, Browne C, Clary D
ContactYan Yang     yan.yang@jax.org     Lab web site
Affiliated CenterJAX In Vivo Services
Project type Phenotype strain survey data set
MPD identifiersJaxwest1     MPD:151
Data changelog 3 updates/corrections.       Initial release date: 06/2004.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Animals were assessed in these areas: body and bone composition, cardiovascular, grip strength, pain sensitivity using DXA system, conscious non-invasive ECG and blood pressure, cold/hot plate analgesia, and grip strength.

Procedures conducted:
• body weight 
• DXA  Body mass, fat mass, lean mass, bone mineral density and content (whole body, femur, spine).
• ECG  Heart rate and wave intervals. Conscious.
• tail cuff  Heart rate and blood pressure. Conscious mice.
• grip strength  Peak tension.
• nociception assay  Hot plate.

Mice: inbred   7 strains   ♀♂   age 8-14wks   1 experimental group