Xing1: Aging study: Electrocardiogram for 29 inbred strains of mice (2008)

Xing S, Tsaih SW, Yuan R, Svenson KL, Jorgenson LM, So M, Paigen BJ, Korstanje R. Genetic influence on electrocardiogram time intervals and heart rate in aging mice. Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1907-13. Epub 2009 Apr 24.   PubMed 19395551     FullText

Due to the difficulties in determining the exact beginning and ending of the T-wave in conscious mice, automatic software generated values for QT and ST intervals should be used with caution; see Figure 4 in the Xing1 protocol.

Xing1 downloads
• Download Xing1 project data set     animal data, as uploaded
• Download Xing1 animal data matrix     with factor-related expansion applied as necessary
• Download Xing1 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Shuqin Xing       The Jackson Laboratory,  Bar Harbor, ME
Ron Korstanje       The Jackson Laboratory,  Bar Harbor, ME
Beverly Paigen       The Jackson Laboratory,  Bar Harbor, ME
Participants Schultz D, Godfrey D
ContactBeverly Paigen     Lab web site
Affiliated CenterJAX Nathan Shock Aging Center
AcknowledgementsFunding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type Phenotype strain survey data set
MPD identifiersXing1     MPD:249
Data changelog 1 update/correction.       Initial release date: 05/2009.
Formatted citation
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Procedures conducted:
• ECG  Heart rate and wave intervals. Conscious. Aging study, 6mo, 12mo, 20mo.

Mice: inbred   29 strains   ♀♂   age 26, 52, 87 wks   3 experimental groups