Bouchard G, Johnson D, Carver T, Paigen B, Carey MC. Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk.
J Lipid Res. 2002 Jul;43(7):1105-13.
Beverly Paigen The Jackson Laboratory, Bar Harbor, ME|
Guylaine Bouchard Hopital Ste-Justine, Montreal, Quebec CANADA
Martin C Carey Harvard Medical School, Boston, MA
With: Johnson D, Tovbina M, Silva A, Carver T, Tracy T, McFarland C, Archer J, Whitmore H
|Contact||Beverly Paigen email@example.com|
|Affiliation||JAX Heart, Lung, and Blood Center (HLB)|
|Part of a series:||
Inbred strains see Paigen1
• Obesity mutant strains (this project) Paigen3
|Acknowledgements||Funding provided by NIH DK51568, HL66611, DK36588, DK34854, DK52911; Medical Research Council of Canada
Generous funds from Aventis Pharmaceuticals Inc. were used to defray the cost of mice through the Mouse Phenome Project.
|Phenotype strain survey data set|
|MPD identifiers||Paigen3 MPD:28|
|4 updates/corrections. Initial release date: 02/2001.|
Click above to copy-paste the entire citation for this MPD web page.
|Summary of procedures that were conducted|
|• body weight||Baseline vs. high-fat diet for 8wks.|
|• lipid profile||Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet.|
|• metabolic panel||Alanine transaminase, bile salts (plasma) after 8wks on high-fat diet. 4h fast.|
|• histopathology||Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet|
|• organ dimensions||Gallbladder volume after 8wks on high-fat diet|
|• organ weights||Liver weight after 8wks on high-fat diet.|