Guay-Woodford LM, Wright CJ, Walz G, Churchill GA. Quantitative trait loci modulate renal cystic disease severity in the mouse bpk model.
J Am Soc Nephrol. 2000 Jul;11(7):1253-60.
Kidney morphology, renal cystic disease severity. |
Investigators |
L M Guay-Woodford Gary A Churchill The Jackson Laboratory, Bar Harbor, ME |
Participants | Guay-Woodford LM, Wright CJ, Walz G, Churchill GA |
Contact | Gary A Churchill gary.churchill@jax.org |
Affiliated Center | QTL Archive |
Acknowledgements | Funding provided by NIH DK51034 |
QTL Archive data set | |
MPD identifiers | Guay-Woodford1 MPD:107 |
No updates/corrections. Initial release date: 01/2008. |
Progenitor strains | BALB/c-Bicc1jcpk-bpk CAST/EiJ |
Cross direction notation | (BALBxCAST) F1 x (BALBxCAST) F1 |
Cross type | F2 intercross |
Population size | 144 ♀ 0 ♂ |
Notes | Sex not specified; arbitrarily set to female. Data are from F2-/- pups. |
Age | 2wks |
Data set |
Procedure / Protocol |
Treatment |
Phenotype Measure / Variable (click to view) |
Panel |
No. of Strains |
Sex |
Age |
Sample Size (Avg)
|
||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
body size and weight | (none) | body length from crown to rump (CR) [cm] body_length 10701 | QTL population | f | N=144 | |||||||
organ dimensions | (none) | length of kidney [mm] kidney_length 10702 | QTL population | f | N=144 | |||||||
organ dimensions | (none) | kidney length normalized to body length [ratio] K_CR 10703 | QTL population | f | N=144 | |||||||
histopathology | (none) | renal cystic disease severity [score] severity 10704 | QTL population | f | N=144 | |||||||