Guay-Woodford LM, Wright CJ, Walz G, Churchill GA. Quantitative trait loci modulate renal cystic disease severity in the mouse bpk model.
J Am Soc Nephrol. 2000 Jul;11(7):1253-60.
| Participants |
L M Guay-Woodford Gary A Churchill The Jackson Laboratory Bar Harbor, ME With: Guay-Woodford LM, Wright CJ, Walz G, Churchill GA |
| Contact | Gary A Churchill gary.churchill@jax.org |
| Affiliation | Churchill Group QTL Archive |
| Acknowledgements | Funding provided by NIH DK51034 |
| QTL Archive data set | |
| MPD identifiers | Guay-Woodford1 MPD:107 |
| No updates/corrections. Initial release date: 01/2008. |
| Progenitor strains | BALB/c-Bicc1jcpk-bpk CAST/EiJ |
| Cross direction notation | (BALBxCAST) F1 x (BALBxCAST) F1 |
| Cross type | F2 intercross |
| Population size | 144 ♀ 0 ♂ |
| Notes | Sex not specified; arbitrarily set to female. Data are from F2-/- pups. |
| Age | 2wks |
| Data set | MPD ID | Procedure / Protocol | Drug or Challenge | Phenotype Measure | Panel | No. of Strains | Sex | Age | Sample Size (Avg) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10701 | body size and weight | (none) | body length from crown to rump (CR) [cm] body_length | QTL population | f | 2wks | N=144 | ||||||
| 10702 | organ dimensions | (none) | length of kidney [mm] kidney_length | QTL population | f | 2wks | N=144 | ||||||
| 10703 | organ dimensions | (none) | kidney length normalized to body length [ratio] K_CR | QTL population | f | 2wks | N=144 | ||||||
| 10704 | histopathology | (none) | renal cystic disease severity [score] severity | QTL population | f | 2wks | N=144 | ||||||