Mahler M, Most C, Schmidtke S, Sundberg JP, Li R, Hedrich HJ, Churchill GA. Genetics of colitis susceptibility in IL-10-deficient mice: backcross versus F2 results contrasted by principal component analysis.
Genomics. 2002 Sep;80(3):274-82.
Investigators |
M Mahler Gary A Churchill The Jackson Laboratory, Bar Harbor, ME |
Participants | Most C, Schmidtke S, Sundberg JP, Li R, Hedrich HJ |
Contact | Gary A Churchill gary.churchill@jax.org |
Affiliated Center | QTL Archive |
Acknowledgements | Funding provided by NIH DK44240, CA34196; and the Deutsche Forschungsgemeinschaft |
QTL Archive data set | |
MPD identifiers | Mahler1 MPD:121 |
No updates/corrections. Initial release date: 01/2008. |
Cross 1: (C3H x B6) x B6 backcross Mahler1 | |
Progenitor strains | B6.Il10-/- C3H.Il10-/- |
Cross direction notation | (C3H x B6) x B6 |
Cross type | Backcross |
Population size | 100 ♀ 103 ♂ |
Notes | N2 progeny |
Age | 6wks |
Cross 2: (C3H x B6) x C3H backcross Mahler1b | |
Progenitor strains | B6.Il10-/- C3H.Il10-/- |
Cross direction notation | (C3H x B6) x C3H |
Cross type | Backcross |
Population size | 116 ♀ 143 ♂ |
Age | 6wks |