CGDpheno3: Multi-system survey of mouse physiology in 8 inbred founder strains and 54 F1 hybrids of the Collaborative Cross (2012)

Lenarcic AB, Svenson KL, Churchill GA, Valdar W. A general Bayesian approach to analyzing diallel crosses of inbred strains. Genetics. 2012 Feb;190(2):413-35.   PubMed 22345610     FullText


       
CGDpheno3 downloads
• Download CGDpheno3 project data set     one row per animal, one column per trait
• Download CGDpheno3 strain means, SD, N, etc.     one row per strain/sex/measure
Institutional authorship Center for Genome Dynamics (CGD)     Lab web site
Participants Svenson KL, Lenarcic AB, Churchill GA, Valdar W
ContactKaren L Svenson     karen.svenson@jax.org     Lab web site
AffiliationCenter for Genome Dynamics (CGD)
AcknowledgementsPartial support from the National Institutes of Health (NIH) Center of Excellence in Genome Sciences grants P50 MH090338 and P50 MH006582, from NIH grant GM076468, from The Jackson Laboratory, and from the University of North Carolina Lineberger Comprehensive Cancer Center.
Project type Phenotype strain survey data set
MPD identifiersCGDpheno3     MPD:439
Data changelog No updates/corrections.       Initial release date: 12/2012.
Formatted citation
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An assessment of F1 hybrids bred from the 8 CC founder strains. Data for the founder strains are also present.

Summary of procedures that were conducted
• metabolic panel Glucose (plasma). 4h fast.
• lipid profile Cholesterol, HDL, triglycerides. 4h fast, plasma.
• complete blood count Hematology.
• tail cuff Heart rate and blood pressure. Conscious mice.
• ECG Wave amplitudes and intervals. Conscious.
• DXA Body mass, fat mass, lean mass, bone mineral density and content, bone area.
• body weight
Mice: CC diallel w/par   62 strains   ♀♂   age 8-16wks   1 cohort