Hunter1: Transgenic survey: Metastatic progression of a mammary tumor determined by genetic background of 28 inbred strains of mice (1998)

Lifsted T, Le Voyer T, Williams M, Muller W, Klein-Szanto A, Buetow KH, Hunter KW. Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int J Cancer. 1998 Aug 12;77(4):640-4.   PubMed 9679770  

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Investigators Kent W Hunter       National Cancer Institute,  Bethesda, MD
Participants Lifsted T, Le Voyer T, Williams M, Muller W, Klein-Szanto A, Buetow KH
ContactKent W Hunter     Lab web site
AcknowledgementsFunding provided by NIH CA06927; American Cancer Society IRG-191A; Department of Defense Breast Cancer Research Program DAMD17-7077; Commonwealth of Pennsylvania; Medical Research Council of Canada; Canadian Breast Cancer Research Initiative
Project type Phenotype strain survey data set
MPD identifiersHunter1     MPD:60
Data changelog No updates/corrections.       Initial release date: 05/2001.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
An investigation of primary mammary tumor latency, severity and metastasis. Subjects were transgene positive (MMTV-PyMT) F1 virgin female progeny of different inbred strains of mice. Primary tumors were noted and confirmed. Mice were analyzed 40 days later (aged to permit metastatic progression).

Procedures conducted:
• histopathology  Metastatic progression of mammary tumor and genetic background.

Mice: MMTV PyVT transgenic   28 strains   ♀   age various   1 experimental group