Hunter1: Transgenic survey: Metastatic progression of a mammary tumor determined by genetic background of 28 inbred strains of mice (1998)

Lifsted T, Le Voyer T, Williams M, Muller W, Klein-Szanto A, Buetow KH, Hunter KW. Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int J Cancer. 1998 Aug 12;77(4):640-4.   PubMed 9679770  


       
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Participants Kent W Hunter       National Cancer Institute Bethesda, MD
With: Lifsted T, Le Voyer T, Williams M, Muller W, Klein-Szanto A, Buetow KH
ContactKent W Hunter     hunterk@mail.nih.gov     Lab web site
AcknowledgementsFunding provided by NIH CA06927; American Cancer Society IRG-191A; Department of Defense Breast Cancer Research Program DAMD17-7077; Commonwealth of Pennsylvania; Medical Research Council of Canada; Canadian Breast Cancer Research Initiative
Project type Phenotype strain survey data set
MPD identifiersHunter1     MPD:60
Data changelog No updates/corrections.       Initial release date: 05/2001.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
An investigation of primary mammary tumor latency, severity and metastasis. Subjects were transgene positive (MMTV-PyMT) F1 virgin female progeny of different inbred strains of mice. Primary tumors were noted and confirmed. Mice were analyzed 40 days later (aged to permit metastatic progression).

Summary of procedures that were conducted
• histopathology Metastatic progression of mammary tumor and genetic background.
Mice: MMTV PyVT transgenic   28 strains   ♀   age various   1 cohort