Open field test, forced swim test, defensive burying task. |
Investigators |
L C Solberg Gary A Churchill The Jackson Laboratory, Bar Harbor, ME |
Contact | Gary A Churchill gary.churchill@jax.org |
Affiliated Center | QTL Archive |
Acknowledgements | Please see the Excel file. |
QTL Archive data set | |
MPD identifiers | Solberg1 MPD:150 |
No updates/corrections. Initial release date: 12/2010. |
Cross direction notation | (FxW) F1 x (FxW) F1; (WxF) F1 x (WxF) F1 |
Cross type | F2 reciprocal intercross |
Population size | 223 ♀ 263 ♂ |
Notes | rat population |
Data set |
Procedure / Protocol |
Treatment |
Phenotype Measure / Variable (click to view) |
Panel |
No. of Strains |
Sex |
Age |
Sample Size (Avg)
|
||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
defensive burying task | (none) | number of times a rat gets shocked in the defensive burying test [n] DBshocks 15001 | QTL population | both | N=243 | |||||||
defensive burying task | (none) | number of times a rat approaches the prod in the defensive burying test [n] DBapproaches 15002 | QTL population | both | N=243 | |||||||
defensive burying task | (none) | latency to begin burying in the defensive burying test [min] DBlatencytobury 15003 | QTL population | both | N=243 | |||||||
defensive burying task | (none) | duration of burying in the defensive burying test [sec] DBdurationofburying 15004 | QTL population | both | N=243 | |||||||
defensive burying task | (none) | number of rears in the defensive burying test [n] DBrears 15005 | QTL population | both | N=243 | |||||||
defensive burying task | (none) | time spent grooming in the defensive burying test [sec] DBgroomtime 15006 | QTL population | both | N=243 | |||||||
forced swim test | (none) | duration of climbing in FST [sec] FSTclimbing 15007 | QTL population | both | N=243 | |||||||
forced swim test | (none) | duration of immobility in FST [sec] FSTimmobility 15008 | QTL population | both | N=243 | |||||||
hormone quantification | (none) | thyroid-stimulating hormone [ng/mL] TSH 15009 | QTL population | both | N=243 | |||||||
open field test | (none) | number of inner lines crossed in the OFT [n] OFTinnerlinecrossing 15010 | QTL population | both | N=243 | |||||||
1. Ahmadiyeh N, Churchill GA, Shimomura K, Solberg LC, Takahashi JS, Redei EE. X-linked and lineage-dependent inheritance of coping responses to stress.
Mamm Genome. 2003 Nov;14(11):748-57.
2. Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Churchill GA, Takahashi JS, Redei EE. Sex- and lineage-specific inheritance of depression-like behavior in the rat.
Mamm Genome. 2004 Aug;15(8):648-62.
3. Baum AE, Solberg LC, Kopp P, Ahmadiyeh N, Churchill G, Takahashi JS, Jameson JL, Redei EE. Quantitative trait loci associated with elevated thyroid-stimulating hormone in the Wistar-Kyoto rat.
Endocrinology. 2005 Feb;146(2):870-8. Epub 2004 Oct 28.
4. Ahmadiyeh N, Churchill GA, Solberg LC, Baum AE, Shimomura K, Takahashi JS, Redei EE. Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress.
Behav Genet. 2005 Mar;35(2):189-98.
5. Baum AE, Solberg LC, Churchill GA, Ahmadiyeh N, Takahashi JS, Redei EE. Test- and behavior-specific genetic factors affect WKY hypoactivity in tests of emotionality.
Behav Brain Res. 2006 May 15;169(2):220-30. Epub 2006 Feb 20.
6. Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Takahashi JS, Churchill GA, Redei EE. Genetic analysis of the stress-responsive adrenocortical axis.
Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8.
7. Solberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EE. Identification of genetic loci involved in diabetes using a rat model of depression.
Mamm Genome. 2009 Aug;20(8):486-97. Epub 2009 Aug 22.