Gros1: Susceptibility to infection with Candida albicans in females of 23 inbred strains of mice (and C5-allele status in 36 strains) (2011)

Radovanovic I, Mullick A, Gros P. Genetic control of susceptibility to infection with Candida albicans in mice. PLoS One. 2011 Apr 20;6(4):e18957.   PubMed 21533108     FullText


         
Procedures conducted:
• in vitro assay  Susceptibility to infection with Candida albicans.
• genotype assessment  C5 allele sufficiency or deficiency.

Gros1 downloads
• Download Gros1 project data set     animal data, as uploaded
• Download Gros1 animal data matrix     with factor-related expansion applied as necessary
• Download Gros1 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Irena Radovanovic       McGill University,  Montreal, Quebec CANADA
Alaka Mullick       Biotechnology Research Institute,  Montreal, Quebec CANADA
Philippe Gros       McGill University,  Montreal, Quebec CANADA
ContactPhilippe Gros     philippe.gros@mcgill.ca     Lab web site
AcknowledgementsFunding provided by Canadian Institutes of Health Research (CIHR)
Project type Phenotype strain survey data set
MPD identifiersGros1     MPD:385
Data changelog 1 update/correction.       Initial release date: 12/2011.
Formatted citation
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Mice: inbred   36 strains   ♀   age 8-12wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    Gros1 in vitro assay Candida albicans kidney fungal load 48h post-infection, colony-forming units (log10 CFU per kidney)   [log(n)]  fungal_load   38501 inbred 23 f 8-12wks N=9
    Gros1 in vitro assay Candida albicans susceptibility to C. albicans based on fungal load (0=susceptible; 1=resistant)   [designation]  susceptibility   38502 inbred 23 f 8-12wks N=9
    Gros1 genotype assessment (none) C5 allele (0=deficient, 1=sufficient)   [designation]  C5_allele   38503 inbred 36 f 8-12wks N=6
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