Benoist1: Survey of regulatory T cells (Treg) of the thymus and spleen in males of 33 inbred strains of mice (2007)

Feuerer M, Jiang W, Holler PD, Satpathy A, Campbell C, Bogue M, Mathis D, Benoist C. Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18181-6. Epub 2007 Nov 8.   PubMed 17991775     FullText


         
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Participants Christophe Benoist       Harvard Medical School,  Boston, MA
Diane Mathis       Harvard Medical School,  Boston, MA
Ansuman Satpathy       Washington University School of Medicine,  St. Louis, MO
Markus Feuerer       Harvard Medical School,  Boston, MA
With: Jiang W, Holler P, Campbell C
ContactChristophe Benoist     Christophe_Benoist@hms.harvard.edu     Lab web site
AcknowledgementsFunding provided by NIH DK60027; German Research Foundation; Juvenile Diabetes Research Foundation 4-2004-368

Mice provided by the Mouse Phenome Project Collaborations Program, The Jackson Laboratory.

Acknowledgements: Technical assistance by Roser L, Hyatt E, Hattori K, LaVecchio J, Buruzala G.
Project type Phenotype strain survey data set
MPD identifiersBenoist1     MPD:258
Data changelog 1 update/correction.       Initial release date: 11/2008.
Formatted citation
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An investigation of strain differences in the production of regulatory T cells in thymus and spleen using flow cytometry.

Summary of procedures that were conducted
• immune cell quantification Regulatory T cells (Treg), thymus, spleen.
Mice: inbred   33 strains   ♂   age 5-6wks   1 experimental group