MPD: Data set: Nadeau2

Procedures conducted:

• body size and weight		Body weight, size, and body mass index after 16wks on high-fat high-sucrose diet.
• metabolic panel		Glucose, insulin, insulin resistance after 16wks of high-fat high-sucrose diet. 16h fast.
• lipid profile		Cholesterol, triglycerides. 16h fast, plasma. Hepatic triglycerides.
• organ weights		Liver weight after 16wks of high-fat high-sucrose diet. 16h fast.

Nadeau2 downloads
• Download Nadeau2 project data set animal data, as uploaded
• Download Nadeau2 animal data matrix with factor-related expansion applied as necessary
• Download Nadeau2 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Nadeau2 measures:

MA:0000358 liver
MA:0002501 plasma
MP:0000180 abnormal circulating cholesterol level
MP:0000188 abnormal circulating glucose level
MP:0001256 abnormal body length
MP:0001259 abnormal body weight
MP:0001560 abnormal circulating insulin level
MP:0004847 abnormal liver weight
MP:0005331 insulin resistance
MP:0011969 abnormal circulating triglyceride level
MP:0012778 abnormal liver triglyceride level
MP:0020182 abnormal body mass index
VT:0000180 blood cholesterol amount
VT:0000188 blood glucose amount
VT:0001256 body length
VT:0001259 body mass
VT:0001560 blood insulin amount
VT:0002644 blood triglyceride amount
VT:0003402 liver mass
VT:0010519 liver triglyceride amount

Investigators	Jesse D Riordan Pacific Northwest Research Institute, Seattle, WA Colleen M Croniger Case Western Reserve University School of Medicine, Cleveland, OH David S Sinasac University of Calgary, Calgary, AB CANADA Joseph H Nadeau Case Western Reserve University School of Medicine, Cleveland, OH
Contact	Joseph H Nadeau jhn4@case.edu Lab web site
Project type	Phenotype strain survey data set
MPD identifiers	Nadeau2 MPD:530
Data changelog	No updates/corrections. Initial release date: 09/2015.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Nadeau2:1	Nadeau2	body size and weight	high-fat high-sucrose diet	body weight [g] bw 53001 baseline after 16wks on diet weight gain	B6.A consomic w/par	24	m	5wks	N=39

Nadeau2:4	Nadeau2	body size and weight	high-fat high-sucrose diet	body length [cm] body_length 53011	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:5	Nadeau2	body size and weight	high-fat high-sucrose diet	body mass index (BMI) [g/cm²] BMI 53012	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:6	Nadeau2	metabolic panel	high-fat high-sucrose diet	glucose (blood GLU, 16h fast) [mmol/L] GLU 53021	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:7	Nadeau2	hormone quantification	high-fat high-sucrose diet	insulin (plasma, 16h fast) [pmol/L] INS 53022	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:8	Nadeau2	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (HOMA-IR, 16h fast) HOMA_IR 53023	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:9	Nadeau2	lipid profile	high-fat high-sucrose diet	total cholesterol (plasma CHOL) [mmol/L] CHOL 53041	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:10	Nadeau2	lipid profile	high-fat high-sucrose diet	triglycerides (plasma TG, 16h fast) [mmol/L] TG 53042	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:11	Nadeau2	organ weights	high-fat high-sucrose diet	liver weight [g] liver_wt 53051	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:12	Nadeau2	lipid profile	high-fat high-sucrose diet	liver triglycerides (mg/g liver) liver_TG 53052	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2:13	Nadeau2	lipid profile	high-fat high-sucrose diet	total liver triglycerides [g] liver_TG_tot 53053	B6.A consomic w/par	24	m	21wks	N=39

Nadeau2: Diet effects on body weight and metabolic traits in the C57BL/6J-Chr#^A/J/NaJ mouse chromosome substitution panel (males) (2015)

Filter Table Results

Nadeau2: Diet effects on body weight and metabolic traits in the C57BL/6J-Chr#A/J/NaJ mouse chromosome substitution panel (males) (2015)

Filter Table Results

Nadeau2: Diet effects on body weight and metabolic traits in the C57BL/6J-Chr#^A/J/NaJ mouse chromosome substitution panel (males) (2015)