MPD: Data set: Schulz1

Schulz1: Lung function survey in 7 inbred strains of mice (2000)

Reinhard C, Eder G, Fuchs H, Ziesenis A, Heyder J, Schulz H. Inbred strain variation in lung function. Mamm Genome. 2002 Aug;13(8):429-37. PubMed 12226708

Procedures conducted:

• ventilator		Lung, respiratory function.
• body weight

Schulz1 downloads
• Download Schulz1 project data set animal data, as uploaded
• Download Schulz1 animal data matrix with factor-related expansion applied as necessary
• Download Schulz1 strain means, SD, N, etc. one row per strain/sex/measure
• Schulz1 supplementary data

Ontology terms mapped to Schulz1 measures:

MA:0000415 lung
MP:0001259 abnormal body weight
MP:0002270 abnormal pulmonary alveolus morphology
MP:0002304 abnormal total lung capacity
MP:0002325 abnormal pulmonary diffusing capacity
MP:0002328 abnormal airway resistance
MP:0002333 abnormal lung compliance
VT:0001183 respiratory alveoli size trait
VT:0001259 body mass
VT:0001942 lung capacity
VT:0001943 respiration trait
VT:0002314 respiratory mechanics trait
VT:0002336 pulmonary gas exchange trait
VT:0002338 pulmonary ventilation trait

Investigators	Holger Schulz GSF Institute for Inhalation Biology, Neuherberg GERMANY
Participants	Reinhard C, Eder G, Fuchs H, Ziesenis A, Heyder J
Contact	Holger Schulz schulz@gsf.de
Acknowledgements	Generous funds from AstraZeneca used to defray the cost of mice through the Mouse Phenome Project.
Project type	Phenotype strain survey data set
MPD identifiers	Schulz1 MPD:16
Data changelog	1 update/correction. Initial release date: 11/2002.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Mice: inbred 7 strains ♀♂ age 9-18wks 1 experimental group

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Schulz1:4	Schulz1	body weight	(none)	body weight [g] bw 1604	inbred	7	both	12-14wks	N=15

Schulz1:5	Schulz1	colony observation	(none)	age (local parameter) [d] age 1605	inbred	7	both		N=16

Schulz1:6	Schulz1	ventilator	(none)	inspiratory capacity (+ 25 cm H₂O) [µL] IC 1606	inbred	7	both	12-14wks	N=15

Schulz1:7	Schulz1	ventilator	(none)	functional residual capacity [µL] FRC 1607	inbred	7	both	12-14wks	N=15

Schulz1:8	Schulz1	ventilator	(none)	total lung capacity [µL] TLC 1608	inbred	7	both	12-14wks	N=15

Schulz1:9	Schulz1	ventilator	(none)	vital capacity [µL] VC 1609	inbred	7	both	12-14wks	N=15

Schulz1:10	Schulz1	ventilator	(none)	dynamic compliance of respiratory system with breathing rate of 130 per min (H₂O pressure) [µL/cm] Cdyn130 1610	inbred	7	both	12-14wks	N=15

Schulz1:11	Schulz1	ventilator	(none)	static compliance of respiratory system (H₂O pressure) [µL/cm] CRS 1611	inbred	7	both	12-14wks	N=15

Schulz1:12	Schulz1	ventilator	(none)	static compliance of lung (H₂O pressure) [µL/cm] CL 1612	inbred	7	both	12-14wks	N=14

Schulz1:13	Schulz1	ventilator	(none)	respiratory system resistance with breathing rate of 130 per min (H₂O pressure) [cm/mL/s] R 1613	inbred	7	both	12-14wks	N=15

Schulz1:14	Schulz1	ventilator	(none)	specific respiratory system resistance with breathing rate of 130 per min related to total lung capacity (H₂O pressure) [cm⋅s] sR 1614	inbred	7	both	12-14wks	N=15

Schulz1:16	Schulz1	ventilator	(none)	intrapulmonary gas mixing: slope of phase III (Hg pressure) [mm/mL] slope 1616	inbred	7	both	12-14wks	N=15

Schulz1:17	Schulz1	ventilator	(none)	alveolar volume [µL] VA 1617	inbred	7	both	12-14wks	N=14

Schulz1:18	Schulz1	ventilator	(none)	diffusing capacity: carbon monoxide [µmol/min/hPa] D_CO 1618	inbred	7	both	12-14wks	N=14

Schulz1:19	Schulz1	ventilator	(none)	specific diffusing capacity: carbon monoxide to alveolar volume [µmol/min/hPa/mL] sD_CO 1619	inbred	7	both	12-14wks	N=14

Schulz1:20	Schulz1	ventilator	(none)	functional residual capacity to total lung capacity [µL/µL] ratio_FRC_TLC 1620	inbred	7	both	12-14wks	N=15

Schulz1:22	Schulz1	ventilator	(none)	total lung capacity to body weight [µL/g] ratio_TLC_bw 1622	inbred	7	both	12-14wks	N=15

Schulz1:23	Schulz1	ventilator	(none)	vital capacity to body weight [L/g] ratio_VC_bw 1623	inbred	7	both	12-14wks	N=15

Schulz1:24	Schulz1	ventilator	(none)	functional residual capacity to body weight [µL/g] ratio_FRC_bw 1624	inbred	7	both	12-14wks	N=14

Schulz1:26	Schulz1	ventilator	(none)	static compliance of lung related to total lung capacity (H₂O pressure) [1/cm] ratio_CL_TLC 1626	inbred	7	both	12-14wks	N=14

Schulz1:27	Schulz1	ventilator	(none)	dynamic compliance of respiratory system (breathing rate 130/min) related to total lung capacity (H₂O pressure) [1/cm] ratio_Cdyn130_TLC 1627	inbred	7	both	12-14wks	N=15

Schulz1:30	Schulz1	ventilator	(none)	Fowler dead space volume to total lung capacity [µL/µL] ratio_VDF_TLC 1630	inbred	7	both	12-14wks	N=15

Schulz1:31	Schulz1	ventilator	(none)	Fowler dead space volume to body weight [µL/g] ratio_VDF_bw 1631	inbred	7	both	12-14wks	N=14

Schulz1:32	Schulz1	ventilator	(none)	Fowler dead space volume [µL] VDF 1632	inbred	7	both	12-14wks	N=15