MPD: Data set: HMDPpheno6

Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ. Genetic regulation of mouse liver metabolite levels. Mol Syst Biol. 2014 May 23;10(5):730. doi: 10.15252/msb.20135004. PubMed 24860088

Investigators	Anatole Ghazalpour University of California, Los Angeles, Los Angeles, CA Brian J Bennett University of North Carolina, Chapel Hill, NC Luz Orozco University of California, Los Angeles, Los Angeles, CA Aldons J Lusis University of California, Los Angeles, Los Angeles, CA
Participants	Shih D, Che N, Pan C, Hagopian R, He A, Kayne P, Yang W-P
Contact	Anatole Ghazalpour aghazalp@ucla.edu Lab web site
Affiliated Center	Hybrid Mouse Diversity Panel Group (HMDP)
Part of a series:	• Metabolite survey: Amino acids (this project) HMDPpheno6 • Metabolite survey: Carbs, cofactors, vitamins, energy, xenobiotics see HMDPpheno7 • Metabolite survey: Lipids (non-lysolipids) see HMDPpheno8 • Metabolite survey: Lipids (lysolipids) see HMDPpheno9 • Metabolite survey: Nucleotides, peptides see HMDPpheno10
Acknowledgements	Funding provided by NIH HL30568, HL28481, HL102223, HG002536, GM07104
Project type	Phenotype strain survey data set
MPD identifiers	HMDPpheno6 MPD:501
Data changelog	No updates/corrections. Initial release date: 06/2014.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
HMDPpheno6:1	HMDPpheno6	metabolite quantification	(none)	liver alanine (16h fast), relative abundance Ala 50101	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:2	HMDPpheno6	metabolite quantification	(none)	liver asparagine (16h fast), relative abundance Asn 50102	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:3	HMDPpheno6	metabolite quantification	(none)	liver aspartate (16h fast), relative abundance Asp 50103	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:4	HMDPpheno6	metabolite quantification	(none)	liver beta-alanine (16h fast), relative abundance beta_Ala 50104	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:5	HMDPpheno6	metabolite quantification	(none)	liver N-acetylasparagine (16h fast), relative abundance acetyl_Asn 50105	HMDP w/par	103	m	16wks	N=1

HMDPpheno6:6	HMDPpheno6	metabolite quantification	(none)	liver N-acetylalanine (16h fast), relative abundance acetyl_Ala 50106	HMDP w/par	104	m	16wks	N=1

HMDPpheno6:7	HMDPpheno6	metabolite quantification	(none)	liver 2-aminobutyrate (16h fast), relative abundance aminobutyrate 50107	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:8	HMDPpheno6	metabolite quantification	(none)	liver creatine (16h fast), relative abundance creatine 50108	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:9	HMDPpheno6	metabolite quantification	(none)	liver 2-hydroxybutyrate (AHB) (16h fast), relative abundance AHB 50109	HMDP w/par	99	m	16wks	N=1

HMDPpheno6:10	HMDPpheno6	metabolite quantification	(none)	liver cysteine (16h fast), relative abundance Cys 50110	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:11	HMDPpheno6	metabolite quantification	(none)	liver hypotaurine (16h fast), relative abundance hypotaurine 50111	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:12	HMDPpheno6	metabolite quantification	(none)	liver methionine (16h fast), relative abundance Met 50112	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:13	HMDPpheno6	metabolite quantification	(none)	liver methionine sulfoxide (16h fast), relative abundance Met_sulf 50113	HMDP w/par	104	m	16wks	N=1

HMDPpheno6:14	HMDPpheno6	metabolite quantification	(none)	liver taurine (16h fast), relative abundance taurine 50114	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:15	HMDPpheno6	metabolite quantification	(none)	liver N-acetylmethionine (16h fast), relative abundance acetyl_Met 50115	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:16	HMDPpheno6	metabolite quantification	(none)	liver S-adenosylhomocysteine (SAH) (16h fast), relative abundance SAH 50116	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:17	HMDPpheno6	metabolite quantification	(none)	liver gamma-aminobutyrate (GABA) (16h fast), relative abundance GABA 50117	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:18	HMDPpheno6	metabolite quantification	(none)	liver N-acetylglutamate (16h fast), relative abundance acetyl_Glu 50118	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:19	HMDPpheno6	metabolite quantification	(none)	liver glutamine (16h fast), relative abundance Gln 50119	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:20	HMDPpheno6	metabolite quantification	(none)	liver glutamate (16h fast), relative abundance Glu 50120	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:21	HMDPpheno6	metabolite quantification	(none)	liver cysteine-glutathione disulfide (16h fast), relative abundance CySSG 50121	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:22	HMDPpheno6	metabolite quantification	(none)	liver glutathione, reduced (GSH) (16h fast), relative abundance GSH 50122	HMDP w/par	104	m	16wks	N=1

HMDPpheno6:23	HMDPpheno6	metabolite quantification	(none)	liver glutathione, oxidized (GSSG) (16h fast), relative abundance GSSG 50123	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:24	HMDPpheno6	metabolite quantification	(none)	liver S-methylglutathione (16h fast), relative abundance Me_glutathione 50124	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:25	HMDPpheno6	metabolite quantification	(none)	liver ophthalmate (16h fast), relative abundance ophthalmate 50125	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:26	HMDPpheno6	metabolite quantification	(none)	liver 5-oxoproline (16h fast), relative abundance oxoproline 50126	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:27	HMDPpheno6	metabolite quantification	(none)	liver N-acetylglycine (16h fast), relative abundance acetyl_Gly 50127	HMDP w/par	96	m	16wks	N=1

HMDPpheno6:28	HMDPpheno6	metabolite quantification	(none)	liver dimethylglycine (16h fast), relative abundance diMe_Gly 50128	HMDP w/par	96	m	16wks	N=1

HMDPpheno6:29	HMDPpheno6	metabolite quantification	(none)	liver glycine (16h fast), relative abundance Gly 50129	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:30	HMDPpheno6	metabolite quantification	(none)	liver homoserine (16h fast), relative abundance homo_Ser 50130	HMDP w/par	104	m	16wks	N=1

HMDPpheno6:31	HMDPpheno6	metabolite quantification	(none)	liver serine (16h fast), relative abundance Ser 50131	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:32	HMDPpheno6	metabolite quantification	(none)	liver threonine (16h fast), relative abundance Thr 50132	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:33	HMDPpheno6	metabolite quantification	(none)	liver betaine (16h fast), relative abundance betaine 50133	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:34	HMDPpheno6	metabolite quantification	(none)	liver betaine aldehyde (16h fast), relative abundance betaine_aldehyde 50134	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:35	HMDPpheno6	metabolite quantification	(none)	liver 3-methylcrotonylglycine (16h fast), relative abundance MeC_Gly 50135	HMDP w/par	98	m	16wks	N=1

HMDPpheno6:36	HMDPpheno6	metabolite quantification	(none)	liver 4-guanidinobutanoate (16h fast), relative abundance guanidino 50136	HMDP w/par	94	m	16wks	N=1

HMDPpheno6:37	HMDPpheno6	metabolite quantification	(none)	liver 1-methylimidazoleacetate (16h fast), relative abundance MeLAA 50137	HMDP w/par	91	m	16wks	N=1

HMDPpheno6:38	HMDPpheno6	metabolite quantification	(none)	liver histidine (16h fast), relative abundance His 50138	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:39	HMDPpheno6	metabolite quantification	(none)	liver glutarate (pentanedioate) (16h fast), relative abundance glutarate 50139	HMDP w/par	100	m	16wks	N=1

HMDPpheno6:40	HMDPpheno6	metabolite quantification	(none)	liver N2-acetyllysine (16h fast), relative abundance acetyl_Lys 50140	HMDP w/par	105	m	16wks	N=1

HMDPpheno6:41	HMDPpheno6	metabolite quantification	(none)	liver 2-aminoadipate (16h fast), relative abundance aminoadipate 50141	HMDP w/par	98	m	16wks	N=1

HMDPpheno6:42	HMDPpheno6	metabolite quantification	(none)	liver glutaroyl carnitine (16h fast), relative abundance GO_carnitine 50142	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:43	HMDPpheno6	metabolite quantification	(none)	liver lysine (16h fast), relative abundance Lys 50143	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:44	HMDPpheno6	metabolite quantification	(none)	liver pipecolate (16h fast), relative abundance pipecolate 50144	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:45	HMDPpheno6	metabolite quantification	(none)	liver phenylalanine (16h fast), relative abundance Phe 50145	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:46	HMDPpheno6	metabolite quantification	(none)	liver tyrosine (16h fast), relative abundance Tyr 50146	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:47	HMDPpheno6	metabolite quantification	(none)	liver 3-(4-hydroxyphenyl)lactate (16h fast), relative abundance HP_lactate 50147	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:48	HMDPpheno6	metabolite quantification	(none)	liver phenylacetylglycine (16h fast), relative abundance PA_Gly 50148	HMDP w/par	105	m	16wks	N=1

HMDPpheno6:49	HMDPpheno6	metabolite quantification	(none)	liver phenol sulfate (16h fast), relative abundance phenol_sulfate 50149	HMDP w/par	103	m	16wks	N=1

HMDPpheno6:50	HMDPpheno6	metabolite quantification	(none)	liver 5-methylthioadenosine (MTA) (16h fast), relative abundance MTA 50150	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:51	HMDPpheno6	metabolite quantification	(none)	liver spermidine (16h fast), relative abundance spermidine 50151	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:52	HMDPpheno6	metabolite quantification	(none)	liver anthranilate (16h fast), relative abundance anthranilate 50152	HMDP w/par	105	m	16wks	N=1

HMDPpheno6:53	HMDPpheno6	metabolite quantification	(none)	liver C-glycosyltryptophan (16h fast), relative abundance glycosyl_Trp 50153	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:54	HMDPpheno6	metabolite quantification	(none)	liver kynurenine (16h fast), relative abundance kynurenine 50154	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:55	HMDPpheno6	metabolite quantification	(none)	liver tryptophan (16h fast), relative abundance Trp 50155	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:56	HMDPpheno6	metabolite quantification	(none)	liver kynurenate (16h fast), relative abundance kynurenate 50156	HMDP w/par	105	m	16wks	N=1

HMDPpheno6:57	HMDPpheno6	metabolite quantification	(none)	liver trans-4-hydroxyproline (16h fast), relative abundance hydroxy_Pro 50157	HMDP w/par	103	m	16wks	N=1

HMDPpheno6:58	HMDPpheno6	metabolite quantification	(none)	liver ornithine (16h fast), relative abundance ornithine 50158	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:59	HMDPpheno6	metabolite quantification	(none)	liver urea (16h fast), relative abundance urea 50159	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:60	HMDPpheno6	metabolite quantification	(none)	liver N-acetylornithine (16h fast), relative abundance acetylornithine 50160	HMDP w/par	103	m	16wks	N=1

HMDPpheno6:61	HMDPpheno6	metabolite quantification	(none)	liver 5-aminovalerate (16h fast), relative abundance aminovalerate 50161	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:62	HMDPpheno6	metabolite quantification	(none)	liver citrulline (16h fast), relative abundance citrulline 50162	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:63	HMDPpheno6	metabolite quantification	(none)	liver homostachydrine (16h fast), relative abundance homostachydrine 50163	HMDP w/par	105	m	16wks	N=1

HMDPpheno6:64	HMDPpheno6	metabolite quantification	(none)	liver proline (16h fast), relative abundance Pro 50164	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:65	HMDPpheno6	metabolite quantification	(none)	liver dimethylarginine (SDMA + ADMA) (16h fast), relative abundance SMDA_ADMA 50165	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:66	HMDPpheno6	metabolite quantification	(none)	liver stachydrine (16h fast), relative abundance stachydrine 50166	HMDP w/par	104	m	16wks	N=1

HMDPpheno6:67	HMDPpheno6	metabolite quantification	(none)	liver hydroxyisovaleroyl carnitine (16h fast), relative abundance HV_carnitine 50167	HMDP w/par	104	m	16wks	N=1

HMDPpheno6:68	HMDPpheno6	metabolite quantification	(none)	liver isobutyrylcarnitine (16h fast), relative abundance IB_carnitine 50168	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:69	HMDPpheno6	metabolite quantification	(none)	liver isoleucine (16h fast), relative abundance Ile 50169	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:70	HMDPpheno6	metabolite quantification	(none)	liver isovalerylcarnitine (16h fast), relative abundance IV_carnitine 50170	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:71	HMDPpheno6	metabolite quantification	(none)	liver isovalerylglycine (16h fast), relative abundance IV_Gly 50171	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:72	HMDPpheno6	metabolite quantification	(none)	liver leucine (16h fast), relative abundance Leu 50172	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:73	HMDPpheno6	metabolite quantification	(none)	liver 2-methylbutyroylcarnitine (16h fast), relative abundance MeB_carnitine 50173	HMDP w/par	105	m	16wks	N=1

HMDPpheno6:74	HMDPpheno6	metabolite quantification	(none)	liver methylglutaroylcarnitine (16h fast), relative abundance MeG_carnitine 50174	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:75	HMDPpheno6	metabolite quantification	(none)	liver tigloylglycine (16h fast), relative abundance tigloyl_Gly 50175	HMDP w/par	92	m	16wks	N=1

HMDPpheno6:76	HMDPpheno6	metabolite quantification	(none)	liver tiglyl carnitine (16h fast), relative abundance tiglyl_carnitine 50176	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:77	HMDPpheno6	metabolite quantification	(none)	liver valine (16h fast), relative abundance Val 50177	HMDP w/par	106	m	16wks	N=1

HMDPpheno6:78	HMDPpheno6	metabolite quantification	(none)	liver methylmalonate (MMA) (16h fast), relative abundance MMA 50178	HMDP w/par	106	m	16wks	N=1

HMDPpheno6: Liver metabolite levels: Amino acids in males of 104 strains of the Hybrid Mouse Diversity Panel (HMDP) (2014)