Project measure / variable:   HMDPpheno6   oxoproline

ID, description, units MPD:50126   oxoproline   liver 5-oxoproline (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 5-oxoproline (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means199349   None
Median of the strain means188594   None
SD of the strain means± 62673
Coefficient of variation (CV)0.314
Min–max range of strain means105874   –   664832   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 123680917529.046 5889567501.3831 1.9857 0.0365
Residuals 34 100842431592.464 2965953870.3666


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 269254.0 0.0   1   0.0 0.0 269254.0, 269254.0 1.12
A/J m 213040.0 27970.0   2   19778.0 0.131 193262.0, 232818.0 0.22
AKR/J m 283326.0 0.0   1   0.0 0.0 283326.0, 283326.0 1.34
AXB10/PgnJ m 168665.0 0.0   1   0.0 0.0 168665.0, 168665.0 -0.49
AXB12/PgnJ m 193914.0 0.0   1   0.0 0.0 193914.0, 193914.0 -0.09
AXB13/PgnJ m 193694.0 0.0   1   0.0 0.0 193694.0, 193694.0 -0.09
AXB15/PgnJ m 221136.0 0.0   1   0.0 0.0 221136.0, 221136.0 0.35
AXB19a/PgnJ m 158341.0 0.0   1   0.0 0.0 158341.0, 158341.0 -0.65
AXB19b/PgnJ m 190766.0 21841.0   2   15444.0 0.114 175323.0, 206210.0 -0.14
AXB19/PgnJ m 163543.0 0.0   1   0.0 0.0 163543.0, 163543.0 -0.57
AXB1/PgnJ m 240270.0 0.0   1   0.0 0.0 240270.0, 240270.0 0.65
AXB23/PgnJ m 185696.0 0.0   1   0.0 0.0 185696.0, 185696.0 -0.22
AXB24/PgnJ m 149403.0 17014.0   2   12031.0 0.114 137372.0, 161434.0 -0.8
AXB2/PgnJ m 266220.0 0.0   1   0.0 0.0 266220.0, 266220.0 1.07
AXB4/PgnJ m 211198.0 0.0   1   0.0 0.0 211198.0, 211198.0 0.19
AXB5/PgnJ m 169291.0 0.0   1   0.0 0.0 169291.0, 169291.0 -0.48
AXB6/PgnJ m 228151.0 0.0   1   0.0 0.0 228151.0, 228151.0 0.46
AXB8/PgnJ m 207273.0 0.0   1   0.0 0.0 207273.0, 207273.0 0.13
BALB/cJ m 206949.0 16188.0   3 9346.0 0.0782 195270.0, 225428.0 0.12
BTBR T+ Itpr3tf/J m 137872.0 0.0   1   0.0 0.0 137872.0, 137872.0 -0.98
BUB/BnJ m 256936.0 0.0   1   0.0 0.0 256936.0, 256936.0 0.92
BXA11/PgnJ m 205974.0 0.0   1   0.0 0.0 205974.0, 205974.0 0.11
BXA12/PgnJ m 249344.0 0.0   1   0.0 0.0 249344.0, 249344.0 0.8
BXA13/PgnJ m 224661.0 0.0   1   0.0 0.0 224661.0, 224661.0 0.4
BXA14/PgnJ m 158738.0 0.0   1   0.0 0.0 158738.0, 158738.0 -0.65
BXA16/PgnJ m 149354.0 28969.0   2   20484.0 0.194 128870.0, 169838.0 -0.8
BXA1/PgnJ m 153769.0 0.0   1   0.0 0.0 153769.0, 153769.0 -0.73
BXA24/PgnJ m 227972.0 0.0   1   0.0 0.0 227972.0, 227972.0 0.46
BXA25/PgnJ m 188076.0 0.0   1   0.0 0.0 188076.0, 188076.0 -0.18
BXA26/PgnJ m 268565.0 0.0   1   0.0 0.0 268565.0, 268565.0 1.1
BXA2/PgnJ m 188280.0 0.0   1   0.0 0.0 188280.0, 188280.0 -0.18
BXA4/PgnJ m 172058.0 0.0   1   0.0 0.0 172058.0, 172058.0 -0.44
BXA7/PgnJ m 190161.0 0.0   1   0.0 0.0 190161.0, 190161.0 -0.15
BXA8/PgnJ m 166087.0 0.0   1   0.0 0.0 166087.0, 166087.0 -0.53
BXD11/TyJ m 222525.0 0.0   1   0.0 0.0 222525.0, 222525.0 0.37
BXD12/TyJ m 279721.0 0.0   1   0.0 0.0 279721.0, 279721.0 1.28
BXD13/TyJ m 154717.0 0.0   1   0.0 0.0 154717.0, 154717.0 -0.71
BXD14/TyJ m 161889.0 0.0   1   0.0 0.0 161889.0, 161889.0 -0.6
BXD15/TyJ m 145057.0 0.0   1   0.0 0.0 145057.0, 145057.0 -0.87
BXD18/TyJ m 142505.0 0.0   1   0.0 0.0 142505.0, 142505.0 -0.91
BXD19/TyJ m 162758.0 23310.0   2   16483.0 0.143 146275.0, 179240.0 -0.58
BXD1/TyJ m 147781.0 0.0   1   0.0 0.0 147781.0, 147781.0 -0.82
BXD20/TyJ m 156520.0 0.0   1   0.0 0.0 156520.0, 156520.0 -0.68
BXD21/TyJ m 161749.0 0.0   1   0.0 0.0 161749.0, 161749.0 -0.6
BXD22/TyJ m 171513.0 0.0   1   0.0 0.0 171513.0, 171513.0 -0.44
BXD24/TyJ m 206133.0 0.0   1   0.0 0.0 206133.0, 206133.0 0.11
BXD24/TyJ-Cep290rd16/J m 176764.0 0.0   1   0.0 0.0 176764.0, 176764.0 -0.36
BXD28/TyJ m 152887.0 1926.0   2   1362.0 0.0126 151525.0, 154250.0 -0.74
BXD29-Tlr4lps-2J/J m 174976.0 0.0   1   0.0 0.0 174976.0, 174976.0 -0.39
BXD2/TyJ m 192107.0 0.0   1   0.0 0.0 192107.0, 192107.0 -0.12
BXD32/TyJ m 248551.0 0.0   1   0.0 0.0 248551.0, 248551.0 0.79
BXD33/TyJ m 150060.0 0.0   1   0.0 0.0 150060.0, 150060.0 -0.79
BXD34/TyJ m 194994.0 0.0   1   0.0 0.0 194994.0, 194994.0 -0.07
BXD36/TyJ m 200693.0 0.0   1   0.0 0.0 200693.0, 200693.0 0.02
BXD38/TyJ m 157639.0 0.0   1   0.0 0.0 157639.0, 157639.0 -0.67
BXD39/TyJ m 107672.0 0.0   1   0.0 0.0 107672.0, 107672.0 -1.46
BXD40/TyJ m 221923.0 0.0   1   0.0 0.0 221923.0, 221923.0 0.36
BXD42/TyJ m 105874.0 0.0   1   0.0 0.0 105874.0, 105874.0 -1.49
BXD5/TyJ m 164600.0 0.0   1   0.0 0.0 164600.0, 164600.0 -0.55
BXD6/TyJ m 134592.0 0.0   1   0.0 0.0 134592.0, 134592.0 -1.03
BXD8/TyJ m 124916.0 0.0   1   0.0 0.0 124916.0, 124916.0 -1.19
BXD9/TyJ m 212542.0 0.0   1   0.0 0.0 212542.0, 212542.0 0.21
BXH10/TyJ m 166446.0 0.0   1   0.0 0.0 166446.0, 166446.0 -0.52
BXH19/TyJ m 155405.0 0.0   1   0.0 0.0 155405.0, 155405.0 -0.7
BXH20/KccJ m 179500.0 0.0   1   0.0 0.0 179500.0, 179500.0 -0.32
BXH22/KccJ m 228273.0 0.0   1   0.0 0.0 228273.0, 228273.0 0.46
BXH2/TyJ m 184249.0 0.0   1   0.0 0.0 184249.0, 184249.0 -0.24
BXH4/TyJ m 160242.0 14255.0   2   10080.0 0.089 150162.0, 170322.0 -0.62
BXH6/TyJ m 156016.0 0.0   1   0.0 0.0 156016.0, 156016.0 -0.69
BXH7/TyJ m 178161.0 0.0   1   0.0 0.0 178161.0, 178161.0 -0.34
BXH8/TyJ m 163460.0 0.0   1   0.0 0.0 163460.0, 163460.0 -0.57
BXH9/TyJ m 186195.0 0.0   1   0.0 0.0 186195.0, 186195.0 -0.21
C3H/HeJ m 230293.0 49335.0   2   34885.0 0.214 195408.0, 265178.0 0.49
C57BL/6J m 264507.0 88103.0   5 39401.0 0.333 201346.0, 418380.0 1.04
C57L/J m 664832.0 0.0   1   0.0 0.0 664832.0, 664832.0 7.43
C58/J m 173080.0 0.0   1   0.0 0.0 173080.0, 173080.0 -0.42
CAST/EiJ m 283179.0 0.0   1   0.0 0.0 283179.0, 283179.0 1.34
CBA/J m 192629.0 0.0   1   0.0 0.0 192629.0, 192629.0 -0.11
CE/J m 259735.0 0.0   1   0.0 0.0 259735.0, 259735.0 0.96
CXB11/HiAJ m 229041.0 5360.0   2   3790.0 0.0234 225251.0, 232832.0 0.47
CXB12/HiAJ m 270150.0 79087.0   2   55923.0 0.293 214227.0, 326073.0 1.13
CXB13/HiAJ m 191482.0 39535.0   3 22825.0 0.206 156814.0, 234537.0 -0.13
CXB1/ByJ m 172133.0 14170.0   3 8181.0 0.0823 155847.0, 181640.0 -0.43
CXB2/ByJ m 283314.0 142107.0   3 82046.0 0.502 181277.0, 445624.0 1.34
CXB3/ByJ m 192991.0 12729.0   2   9001.0 0.066 183990.0, 201991.0 -0.1
CXB4/ByJ m 166030.0 9116.0   2   6446.0 0.0549 159584.0, 172476.0 -0.53
CXB6/ByJ m 277875.0 55553.0   3 32073.0 0.2 222790.0, 333884.0 1.25
CXB7/ByJ m 166983.0 12376.0   2   8751.0 0.0741 158232.0, 175734.0 -0.52
CXB8/HiAJ m 170671.0 22026.0   3 12717.0 0.129 157607.0, 196102.0 -0.46
CXB9/HiAJ m 243475.0 52059.0   3 30056.0 0.214 200579.0, 301393.0 0.7
DBA/2J m 139879.0 13371.0   4 6685.0 0.0956 126658.0, 155607.0 -0.95
FVB/NJ m 249134.0 0.0   1   0.0 0.0 249134.0, 249134.0 0.79
I/LnJ m 194053.0 0.0   1   0.0 0.0 194053.0, 194053.0 -0.08
KK/HlJ m 188908.0 0.0   1   0.0 0.0 188908.0, 188908.0 -0.17
LG/J m 190863.0 0.0   1   0.0 0.0 190863.0, 190863.0 -0.14
LP/J m 186091.0 0.0   1   0.0 0.0 186091.0, 186091.0 -0.21
MA/MyJ m 309586.0 0.0   1   0.0 0.0 309586.0, 309586.0 1.76
NOD/ShiLtJ m 261615.0 0.0   1   0.0 0.0 261615.0, 261615.0 0.99
NON/ShiLtJ m 190265.0 0.0   1   0.0 0.0 190265.0, 190265.0 -0.14
NZW/LacJ m 166470.0 0.0   1   0.0 0.0 166470.0, 166470.0 -0.52
PL/J m 220230.0 0.0   1   0.0 0.0 220230.0, 220230.0 0.33
RIIIS/J m 171134.0 0.0   1   0.0 0.0 171134.0, 171134.0 -0.45
SEA/GnJ m 245248.0 0.0   1   0.0 0.0 245248.0, 245248.0 0.73
SJL/J m 161400.0 0.0   1   0.0 0.0 161400.0, 161400.0 -0.61
SM/J m 168232.0 0.0   1   0.0 0.0 168232.0, 168232.0 -0.5
SWR/J m 205938.0 0.0   1   0.0 0.0 205938.0, 205938.0 0.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 213039.85 38509.4396 291300.4471 134779.2529
AXB19b/PgnJ m 190766.25 38509.4396 269026.8471 112505.6529
AXB24/PgnJ m 149402.8 38509.4396 227663.3971 71142.2029
BALB/cJ m 206949.1667 31442.8257 270848.6766 143049.6567
BXA16/PgnJ m 149354.1 38509.4396 227614.6971 71093.5029
BXD19/TyJ m 162757.5 38509.4396 241018.0971 84496.9029
BXD28/TyJ m 152887.4 38509.4396 231147.9971 74626.8029
BXH4/TyJ m 160242.25 38509.4396 238502.8471 81981.6529
C3H/HeJ m 230292.95 38509.4396 308553.5471 152032.3529
C57BL/6J m 264506.6 24355.5081 314002.9476 215010.2524
CXB11/HiAJ m 229041.4 38509.4396 307301.9971 150780.8029
CXB12/HiAJ m 270150.25 38509.4396 348410.8471 191889.6529
CXB13/HiAJ m 191481.7333 31442.8257 255381.2433 127582.2234
CXB1/ByJ m 172132.8667 31442.8257 236032.3766 108233.3567
CXB2/ByJ m 283313.6 31442.8257 347213.11 219414.09
CXB3/ByJ m 192990.65 38509.4396 271251.2471 114730.0529
CXB4/ByJ m 166030.0 38509.4396 244290.5971 87769.4029
CXB6/ByJ m 277875.0 31442.8257 341774.51 213975.49
CXB7/ByJ m 166983.2 38509.4396 245243.7971 88722.6029
CXB8/HiAJ m 170671.0333 31442.8257 234570.5433 106771.5234
CXB9/HiAJ m 243475.2 31442.8257 307374.71 179575.69
DBA/2J m 139879.475 27230.2859 195218.0739 84540.8761




  GWAS USING LINEAR MIXED MODELS