Project measure / variable:   HMDPpheno6   aminoadipate

ID, description, units MPD:50141   aminoadipate   liver 2-aminoadipate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   98 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 2-aminoadipate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested98 strains
Mean of the strain means1323789   None
Median of the strain means290463   None
SD of the strain means± 4617011
Coefficient of variation (CV)3.49
Min–max range of strain means17357   –   30489014   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 19 115007031636882.0 6053001665099.07 7.7743 < 0.0001
Residuals 30 23357781133828.3 778592704460.944


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 161393.0 0.0   1   0.0 0.0 161393.0, 161393.0 -0.25
A/J m 607713.0 544537.0   2   385046.0 0.896 222666.0, 992759.0 -0.16
AKR/J m 433756.0 0.0   1   0.0 0.0 433756.0, 433756.0 -0.19
AXB10/PgnJ m 200837.0 0.0   1   0.0 0.0 200837.0, 200837.0 -0.24
AXB12/PgnJ m 912476.0 0.0   1   0.0 0.0 912476.0, 912476.0 -0.09
AXB13/PgnJ m 173672.0 0.0   1   0.0 0.0 173672.0, 173672.0 -0.25
AXB15/PgnJ m 170199.0 0.0   1   0.0 0.0 170199.0, 170199.0 -0.25
AXB19a/PgnJ m 387152.0 0.0   1   0.0 0.0 387152.0, 387152.0 -0.2
AXB19b/PgnJ m 332224.0 57529.0   2   40679.0 0.173 291546.0, 372903.0 -0.21
AXB19/PgnJ m 217869.0 0.0   1   0.0 0.0 217869.0, 217869.0 -0.24
AXB1/PgnJ m 27039106.0 0.0   1   0.0 0.0 27039106.0, 27039106.0 5.57
AXB23/PgnJ m 158065.0 0.0   1   0.0 0.0 158065.0, 158065.0 -0.25
AXB24/PgnJ m 634058.0 559068.0   2   395321.0 0.882 238737.0, 1029379.0 -0.15
AXB2/PgnJ m 8304871.0 0.0   1   0.0 0.0 8304871.0, 8304871.0 1.51
AXB4/PgnJ m 2313981.0 0.0   1   0.0 0.0 2313981.0, 2313981.0 0.21
AXB5/PgnJ m 416202.0 0.0   1   0.0 0.0 416202.0, 416202.0 -0.2
AXB6/PgnJ m 241242.0 0.0   1   0.0 0.0 241242.0, 241242.0 -0.23
AXB8/PgnJ m 412991.0 0.0   1   0.0 0.0 412991.0, 412991.0 -0.2
BALB/cJ m 380444.0 54987.0   3 31747.0 0.145 329652.0, 438836.0 -0.2
BTBR T+ Itpr3tf/J m 73007.0 0.0   1   0.0 0.0 73007.0, 73007.0 -0.27
BUB/BnJ m 789260.0 0.0   1   0.0 0.0 789260.0, 789260.0 -0.12
BXA12/PgnJ m 983385.0 0.0   1   0.0 0.0 983385.0, 983385.0 -0.07
BXA13/PgnJ m 290463.0 0.0   1   0.0 0.0 290463.0, 290463.0 -0.22
BXA14/PgnJ m 607104.0 0.0   1   0.0 0.0 607104.0, 607104.0 -0.16
BXA16/PgnJ m 769489.0 573123.0   2   405259.0 0.745 364230.0, 1174748.0 -0.12
BXA1/PgnJ m 121640.0 0.0   1   0.0 0.0 121640.0, 121640.0 -0.26
BXA24/PgnJ m 331259.0 0.0   1   0.0 0.0 331259.0, 331259.0 -0.21
BXA25/PgnJ m 247128.0 0.0   1   0.0 0.0 247128.0, 247128.0 -0.23
BXA26/PgnJ m 581854.0 0.0   1   0.0 0.0 581854.0, 581854.0 -0.16
BXA2/PgnJ m 450095.0 0.0   1   0.0 0.0 450095.0, 450095.0 -0.19
BXA4/PgnJ m 264774.0 0.0   1   0.0 0.0 264774.0, 264774.0 -0.23
BXA7/PgnJ m 320822.0 0.0   1   0.0 0.0 320822.0, 320822.0 -0.22
BXA8/PgnJ m 141456.0 0.0   1   0.0 0.0 141456.0, 141456.0 -0.26
BXD11/TyJ m 890459.0 0.0   1   0.0 0.0 890459.0, 890459.0 -0.09
BXD12/TyJ m 309166.0 0.0   1   0.0 0.0 309166.0, 309166.0 -0.22
BXD13/TyJ m 195182.0 0.0   1   0.0 0.0 195182.0, 195182.0 -0.24
BXD14/TyJ m 397265.0 0.0   1   0.0 0.0 397265.0, 397265.0 -0.2
BXD15/TyJ m 290463.0 0.0   1   0.0 0.0 290463.0, 290463.0 -0.22
BXD18/TyJ m 270341.0 0.0   1   0.0 0.0 270341.0, 270341.0 -0.23
BXD19/TyJ m 215287.0 63209.0   2   44696.0 0.294 170591.0, 259983.0 -0.24
BXD20/TyJ m 1024659.0 0.0   1   0.0 0.0 1024659.0, 1024659.0 -0.06
BXD22/TyJ m 252131.0 0.0   1   0.0 0.0 252131.0, 252131.0 -0.23
BXD24/TyJ m 173554.0 0.0   1   0.0 0.0 173554.0, 173554.0 -0.25
BXD24/TyJ-Cep290rd16/J m 125131.0 0.0   1   0.0 0.0 125131.0, 125131.0 -0.26
BXD28/TyJ m 256827.0 29321.0   2   20733.0 0.114 236094.0, 277560.0 -0.23
BXD2/TyJ m 371011.0 0.0   1   0.0 0.0 371011.0, 371011.0 -0.21
BXD32/TyJ m 1816237.0 0.0   1   0.0 0.0 1816237.0, 1816237.0 0.11
BXD33/TyJ m 606226.0 0.0   1   0.0 0.0 606226.0, 606226.0 -0.16
BXD34/TyJ m 398790.0 0.0   1   0.0 0.0 398790.0, 398790.0 -0.2
BXD36/TyJ m 160530.0 0.0   1   0.0 0.0 160530.0, 160530.0 -0.25
BXD38/TyJ m 369702.0 0.0   1   0.0 0.0 369702.0, 369702.0 -0.21
BXD39/TyJ m 138143.0 0.0   1   0.0 0.0 138143.0, 138143.0 -0.26
BXD40/TyJ m 122530.0 0.0   1   0.0 0.0 122530.0, 122530.0 -0.26
BXD5/TyJ m 163498.0 0.0   1   0.0 0.0 163498.0, 163498.0 -0.25
BXD6/TyJ m 523598.0 0.0   1   0.0 0.0 523598.0, 523598.0 -0.17
BXD8/TyJ m 2162368.0 0.0   1   0.0 0.0 2162368.0, 2162368.0 0.18
BXD9/TyJ m 17357.0 0.0   1   0.0 0.0 17357.0, 17357.0 -0.28
BXH10/TyJ m 326046.0 0.0   1   0.0 0.0 326046.0, 326046.0 -0.22
BXH19/TyJ m 155337.0 0.0   1   0.0 0.0 155337.0, 155337.0 -0.25
BXH20/KccJ m 169738.0 0.0   1   0.0 0.0 169738.0, 169738.0 -0.25
BXH22/KccJ m 160997.0 0.0   1   0.0 0.0 160997.0, 160997.0 -0.25
BXH4/TyJ m 97252.0 0.0   1   0.0 0.0 97252.0, 97252.0 -0.27
BXH7/TyJ m 289381.0 0.0   1   0.0 0.0 289381.0, 289381.0 -0.22
BXH8/TyJ m 356325.0 0.0   1   0.0 0.0 356325.0, 356325.0 -0.21
BXH9/TyJ m 270113.0 0.0   1   0.0 0.0 270113.0, 270113.0 -0.23
C3H/HeJ m 165178.0 78452.0   2   55474.0 0.475 109704.0, 220652.0 -0.25
C57BL/6J m 5368534.0 2345014.0   5 1048722.0 0.437 2800487.0, 8575854.0 0.88
C57L/J m 1259241.0 0.0   1   0.0 0.0 1259241.0, 1259241.0 -0.01
C58/J m 30489014.0 0.0   1   0.0 0.0 30489014.0, 30489014.0 6.32
CAST/EiJ m 101649.0 0.0   1   0.0 0.0 101649.0, 101649.0 -0.26
CBA/J m 105435.0 0.0   1   0.0 0.0 105435.0, 105435.0 -0.26
CE/J m 408601.0 0.0   1   0.0 0.0 408601.0, 408601.0 -0.2
CXB11/HiAJ m 165931.0 43063.0   2   30450.0 0.26 135481.0, 196381.0 -0.25
CXB12/HiAJ m 206951.0 118104.0   2   83512.0 0.571 123438.0, 290463.0 -0.24
CXB13/HiAJ m 317381.0 146992.0   3 84866.0 0.463 182725.0, 474193.0 -0.22
CXB1/ByJ m 208646.0 115221.0   3 66523.0 0.552 75680.0, 279120.0 -0.24
CXB2/ByJ m 567696.0 324468.0   3 187331.0 0.572 356506.0, 941299.0 -0.16
CXB3/ByJ m 288376.0 24360.0   2   17225.0 0.0845 271151.0, 305601.0 -0.22
CXB4/ByJ m 174419.0 1945.0   2   1375.0 0.0112 173044.0, 175794.0 -0.25
CXB6/ByJ m 725998.0 216289.0   3 124874.0 0.298 553379.0, 968617.0 -0.13
CXB7/ByJ m 206631.0 87634.0   2   61966.0 0.424 144665.0, 268597.0 -0.24
CXB8/HiAJ m 159925.0 3960.0   3 2286.0 0.0248 155388.0, 162687.0 -0.25
CXB9/HiAJ m 238992.0 52485.0   3 30302.0 0.22 185548.0, 290463.0 -0.23
FVB/NJ m 544873.0 0.0   1   0.0 0.0 544873.0, 544873.0 -0.17
I/LnJ m 223779.0 0.0   1   0.0 0.0 223779.0, 223779.0 -0.24
KK/HlJ m 304590.0 0.0   1   0.0 0.0 304590.0, 304590.0 -0.22
LG/J m 138136.0 0.0   1   0.0 0.0 138136.0, 138136.0 -0.26
LP/J m 180161.0 0.0   1   0.0 0.0 180161.0, 180161.0 -0.25
MA/MyJ m 467128.0 0.0   1   0.0 0.0 467128.0, 467128.0 -0.19
NOD/ShiLtJ m 811858.0 0.0   1   0.0 0.0 811858.0, 811858.0 -0.11
NON/ShiLtJ m 493793.0 0.0   1   0.0 0.0 493793.0, 493793.0 -0.18
NZW/LacJ m 148928.0 0.0   1   0.0 0.0 148928.0, 148928.0 -0.25
PL/J m 224193.0 0.0   1   0.0 0.0 224193.0, 224193.0 -0.24
RIIIS/J m 374335.0 0.0   1   0.0 0.0 374335.0, 374335.0 -0.21
SEA/GnJ m 186101.0 0.0   1   0.0 0.0 186101.0, 186101.0 -0.25
SJL/J m 263038.0 0.0   1   0.0 0.0 263038.0, 263038.0 -0.23
SM/J m 21258904.0 0.0   1   0.0 0.0 21258904.0, 21258904.0 4.32
SWR/J m 407238.0 0.0   1   0.0 0.0 407238.0, 407238.0 -0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 607712.65 623936.1764 1881960.3176 0.0
AXB19b/PgnJ m 332224.45 623936.1764 1606472.1176 0.0
AXB24/PgnJ m 634058.05 623936.1764 1908305.7176 0.0
BALB/cJ m 380444.3333 509441.7548 1420863.1972 0.0
BXA16/PgnJ m 769489.45 623936.1764 2043737.1176 0.0
BXD19/TyJ m 215286.95 623936.1764 1489534.6176 0.0
BXD28/TyJ m 256827.35 623936.1764 1531075.0176 0.0
C3H/HeJ m 165178.05 623936.1764 1439425.7176 0.0
C57BL/6J m 5368534.36 394611.8864 6174439.3465 4562629.3735
CXB11/HiAJ m 165931.1 623936.1764 1440178.7676 0.0
CXB12/HiAJ m 206950.75 623936.1764 1481198.4176 0.0
CXB13/HiAJ m 317381.1333 509441.7548 1357799.9972 0.0
CXB1/ByJ m 208646.2667 509441.7548 1249065.1305 0.0
CXB2/ByJ m 567695.9333 509441.7548 1608114.7972 0.0
CXB3/ByJ m 288376.1 623936.1764 1562623.7676 0.0
CXB4/ByJ m 174419.2 623936.1764 1448666.8676 0.0
CXB6/ByJ m 725998.0 509441.7548 1766416.8638 0.0
CXB7/ByJ m 206631.0 623936.1764 1480878.6676 0.0
CXB8/HiAJ m 159925.0667 509441.7548 1200343.9305 0.0
CXB9/HiAJ m 238991.6667 509441.7548 1279410.5305 0.0




  GWAS USING LINEAR MIXED MODELS