Project measure / variable:   HMDPpheno6   GABA

ID, description, units MPD:50117   GABA   liver gamma-aminobutyrate (GABA) (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver gamma-aminobutyrate (GABA) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means409807   None
Median of the strain means391876   None
SD of the strain means± 152109
Coefficient of variation (CV)0.371
Min–max range of strain means150585   –   941059   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 616820369903.162 29372398566.8173 2.3071 0.0146
Residuals 34 432859194971.86 12731152793.29


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 818642.0 0.0   1   0.0 0.0 818642.0, 818642.0 2.69
A/J m 344093.0 8633.0   2   6104.0 0.0251 337988.0, 350197.0 -0.43
AKR/J m 246101.0 0.0   1   0.0 0.0 246101.0, 246101.0 -1.08
AXB10/PgnJ m 473252.0 0.0   1   0.0 0.0 473252.0, 473252.0 0.42
AXB12/PgnJ m 378957.0 0.0   1   0.0 0.0 378957.0, 378957.0 -0.2
AXB13/PgnJ m 471593.0 0.0   1   0.0 0.0 471593.0, 471593.0 0.41
AXB15/PgnJ m 263206.0 0.0   1   0.0 0.0 263206.0, 263206.0 -0.96
AXB19a/PgnJ m 441476.0 0.0   1   0.0 0.0 441476.0, 441476.0 0.21
AXB19b/PgnJ m 491006.0 4680.0   2   3309.0 0.00953 487696.0, 494315.0 0.53
AXB19/PgnJ m 398382.0 0.0   1   0.0 0.0 398382.0, 398382.0 -0.08
AXB1/PgnJ m 282410.0 0.0   1   0.0 0.0 282410.0, 282410.0 -0.84
AXB23/PgnJ m 316810.0 0.0   1   0.0 0.0 316810.0, 316810.0 -0.61
AXB24/PgnJ m 381766.0 141857.0   2   100308.0 0.372 281458.0, 482074.0 -0.18
AXB2/PgnJ m 308474.0 0.0   1   0.0 0.0 308474.0, 308474.0 -0.67
AXB4/PgnJ m 521931.0 0.0   1   0.0 0.0 521931.0, 521931.0 0.74
AXB5/PgnJ m 423809.0 0.0   1   0.0 0.0 423809.0, 423809.0 0.09
AXB6/PgnJ m 412926.0 0.0   1   0.0 0.0 412926.0, 412926.0 0.02
AXB8/PgnJ m 447960.0 0.0   1   0.0 0.0 447960.0, 447960.0 0.25
BALB/cJ m 456067.0 97838.0   3 56487.0 0.215 343131.0, 515074.0 0.3
BTBR T+ Itpr3tf/J m 455010.0 0.0   1   0.0 0.0 455010.0, 455010.0 0.3
BUB/BnJ m 344309.0 0.0   1   0.0 0.0 344309.0, 344309.0 -0.43
BXA11/PgnJ m 213298.0 0.0   1   0.0 0.0 213298.0, 213298.0 -1.29
BXA12/PgnJ m 275540.0 0.0   1   0.0 0.0 275540.0, 275540.0 -0.88
BXA13/PgnJ m 372055.0 0.0   1   0.0 0.0 372055.0, 372055.0 -0.25
BXA14/PgnJ m 568958.0 0.0   1   0.0 0.0 568958.0, 568958.0 1.05
BXA16/PgnJ m 437465.0 333061.0   2   235509.0 0.761 201956.0, 672974.0 0.18
BXA1/PgnJ m 596802.0 0.0   1   0.0 0.0 596802.0, 596802.0 1.23
BXA24/PgnJ m 661122.0 0.0   1   0.0 0.0 661122.0, 661122.0 1.65
BXA25/PgnJ m 360856.0 0.0   1   0.0 0.0 360856.0, 360856.0 -0.32
BXA26/PgnJ m 455121.0 0.0   1   0.0 0.0 455121.0, 455121.0 0.3
BXA2/PgnJ m 533174.0 0.0   1   0.0 0.0 533174.0, 533174.0 0.81
BXA4/PgnJ m 334344.0 0.0   1   0.0 0.0 334344.0, 334344.0 -0.5
BXA7/PgnJ m 512460.0 0.0   1   0.0 0.0 512460.0, 512460.0 0.67
BXA8/PgnJ m 283238.0 0.0   1   0.0 0.0 283238.0, 283238.0 -0.83
BXD11/TyJ m 340958.0 0.0   1   0.0 0.0 340958.0, 340958.0 -0.45
BXD12/TyJ m 422445.0 0.0   1   0.0 0.0 422445.0, 422445.0 0.08
BXD13/TyJ m 255329.0 0.0   1   0.0 0.0 255329.0, 255329.0 -1.02
BXD14/TyJ m 345558.0 0.0   1   0.0 0.0 345558.0, 345558.0 -0.42
BXD15/TyJ m 185067.0 0.0   1   0.0 0.0 185067.0, 185067.0 -1.48
BXD18/TyJ m 506605.0 0.0   1   0.0 0.0 506605.0, 506605.0 0.64
BXD19/TyJ m 340361.0 77413.0   2   54739.0 0.227 285622.0, 395100.0 -0.46
BXD1/TyJ m 280339.0 0.0   1   0.0 0.0 280339.0, 280339.0 -0.85
BXD20/TyJ m 313513.0 0.0   1   0.0 0.0 313513.0, 313513.0 -0.63
BXD21/TyJ m 304026.0 0.0   1   0.0 0.0 304026.0, 304026.0 -0.7
BXD22/TyJ m 364903.0 0.0   1   0.0 0.0 364903.0, 364903.0 -0.3
BXD24/TyJ m 306003.0 0.0   1   0.0 0.0 306003.0, 306003.0 -0.68
BXD24/TyJ-Cep290rd16/J m 338720.0 0.0   1   0.0 0.0 338720.0, 338720.0 -0.47
BXD28/TyJ m 485311.0 34186.0   2   24173.0 0.0704 461137.0, 509484.0 0.5
BXD29-Tlr4lps-2J/J m 246961.0 0.0   1   0.0 0.0 246961.0, 246961.0 -1.07
BXD2/TyJ m 347166.0 0.0   1   0.0 0.0 347166.0, 347166.0 -0.41
BXD32/TyJ m 590211.0 0.0   1   0.0 0.0 590211.0, 590211.0 1.19
BXD33/TyJ m 297622.0 0.0   1   0.0 0.0 297622.0, 297622.0 -0.74
BXD34/TyJ m 310570.0 0.0   1   0.0 0.0 310570.0, 310570.0 -0.65
BXD36/TyJ m 410888.0 0.0   1   0.0 0.0 410888.0, 410888.0 0.01
BXD38/TyJ m 159339.0 0.0   1   0.0 0.0 159339.0, 159339.0 -1.65
BXD39/TyJ m 179873.0 0.0   1   0.0 0.0 179873.0, 179873.0 -1.51
BXD40/TyJ m 512417.0 0.0   1   0.0 0.0 512417.0, 512417.0 0.67
BXD42/TyJ m 197713.0 0.0   1   0.0 0.0 197713.0, 197713.0 -1.39
BXD5/TyJ m 376054.0 0.0   1   0.0 0.0 376054.0, 376054.0 -0.22
BXD6/TyJ m 408686.0 0.0   1   0.0 0.0 408686.0, 408686.0 -0.01
BXD8/TyJ m 150585.0 0.0   1   0.0 0.0 150585.0, 150585.0 -1.7
BXD9/TyJ m 560753.0 0.0   1   0.0 0.0 560753.0, 560753.0 0.99
BXH10/TyJ m 518563.0 0.0   1   0.0 0.0 518563.0, 518563.0 0.71
BXH19/TyJ m 941059.0 0.0   1   0.0 0.0 941059.0, 941059.0 3.49
BXH20/KccJ m 594681.0 0.0   1   0.0 0.0 594681.0, 594681.0 1.22
BXH22/KccJ m 432022.0 0.0   1   0.0 0.0 432022.0, 432022.0 0.15
BXH2/TyJ m 538138.0 0.0   1   0.0 0.0 538138.0, 538138.0 0.84
BXH4/TyJ m 381587.0 70814.0   2   50073.0 0.186 331514.0, 431660.0 -0.19
BXH6/TyJ m 589708.0 0.0   1   0.0 0.0 589708.0, 589708.0 1.18
BXH7/TyJ m 460628.0 0.0   1   0.0 0.0 460628.0, 460628.0 0.33
BXH8/TyJ m 412527.0 0.0   1   0.0 0.0 412527.0, 412527.0 0.02
BXH9/TyJ m 387538.0 0.0   1   0.0 0.0 387538.0, 387538.0 -0.15
C3H/HeJ m 380128.0 43184.0   2   30536.0 0.114 349592.0, 410663.0 -0.2
C57BL/6J m 565550.0 54668.0   5 24448.0 0.0967 491750.0, 625260.0 1.02
C57L/J m 256010.0 0.0   1   0.0 0.0 256010.0, 256010.0 -1.01
C58/J m 466516.0 0.0   1   0.0 0.0 466516.0, 466516.0 0.37
CAST/EiJ m 895259.0 0.0   1   0.0 0.0 895259.0, 895259.0 3.19
CBA/J m 202214.0 0.0   1   0.0 0.0 202214.0, 202214.0 -1.36
CE/J m 370136.0 0.0   1   0.0 0.0 370136.0, 370136.0 -0.26
CXB11/HiAJ m 414496.0 208006.0   2   147082.0 0.502 267414.0, 561578.0 0.03
CXB12/HiAJ m 396213.0 36511.0   2   25817.0 0.0921 370396.0, 422030.0 -0.09
CXB13/HiAJ m 486630.0 100120.0   3 57804.0 0.206 382815.0, 582592.0 0.51
CXB1/ByJ m 559398.0 103030.0   3 59484.0 0.184 447776.0, 650853.0 0.98
CXB2/ByJ m 399738.0 181348.0   3 104701.0 0.454 200743.0, 555695.0 -0.07
CXB3/ByJ m 458901.0 159308.0   2   112648.0 0.347 346253.0, 571549.0 0.32
CXB4/ByJ m 773065.0 152972.0   2   108168.0 0.198 664898.0, 881233.0 2.39
CXB6/ByJ m 511563.0 114339.0   3 66013.0 0.224 423169.0, 640691.0 0.67
CXB7/ByJ m 585732.0 83208.0   2   58837.0 0.142 526895.0, 644569.0 1.16
CXB8/HiAJ m 451310.0 52288.0   3 30188.0 0.116 399106.0, 503681.0 0.27
CXB9/HiAJ m 506293.0 92621.0   3 53475.0 0.183 409024.0, 593434.0 0.63
DBA/2J m 255733.0 12157.0   4 6078.0 0.0475 237531.0, 262331.0 -1.01
FVB/NJ m 443447.0 0.0   1   0.0 0.0 443447.0, 443447.0 0.22
I/LnJ m 426450.0 0.0   1   0.0 0.0 426450.0, 426450.0 0.11
KK/HlJ m 252925.0 0.0   1   0.0 0.0 252925.0, 252925.0 -1.03
LG/J m 271628.0 0.0   1   0.0 0.0 271628.0, 271628.0 -0.91
LP/J m 555447.0 0.0   1   0.0 0.0 555447.0, 555447.0 0.96
MA/MyJ m 336512.0 0.0   1   0.0 0.0 336512.0, 336512.0 -0.48
NOD/ShiLtJ m 282940.0 0.0   1   0.0 0.0 282940.0, 282940.0 -0.83
NON/ShiLtJ m 335159.0 0.0   1   0.0 0.0 335159.0, 335159.0 -0.49
NZW/LacJ m 223365.0 0.0   1   0.0 0.0 223365.0, 223365.0 -1.23
PL/J m 370256.0 0.0   1   0.0 0.0 370256.0, 370256.0 -0.26
RIIIS/J m 236642.0 0.0   1   0.0 0.0 236642.0, 236642.0 -1.14
SEA/GnJ m 327758.0 0.0   1   0.0 0.0 327758.0, 327758.0 -0.54
SJL/J m 260568.0 0.0   1   0.0 0.0 260568.0, 260568.0 -0.98
SM/J m 226552.0 0.0   1   0.0 0.0 226552.0, 226552.0 -1.2
SWR/J m 877976.0 0.0   1   0.0 0.0 877976.0, 877976.0 3.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 344092.8 79784.5624 506234.5389 181951.0611
AXB19b/PgnJ m 491005.5 79784.5624 653147.2389 328863.7611
AXB24/PgnJ m 381765.85 79784.5624 543907.5889 219624.1111
BALB/cJ m 456066.7667 65143.8224 588454.9421 323678.5913
BXA16/PgnJ m 437465.05 79784.5624 599606.7889 275323.3111
BXD19/TyJ m 340361.3 79784.5624 502503.0389 178219.5611
BXD28/TyJ m 485310.75 79784.5624 647452.4889 323169.0111
BXH4/TyJ m 381587.4 79784.5624 543729.1389 219445.6611
C3H/HeJ m 380127.5 79784.5624 542269.2389 217985.7611
C57BL/6J m 565550.24 50460.1879 668097.6797 463002.8003
CXB11/HiAJ m 414496.3 79784.5624 576638.0389 252354.5611
CXB12/HiAJ m 396212.65 79784.5624 558354.3889 234070.9111
CXB13/HiAJ m 486630.1333 65143.8224 619018.3087 354241.9579
CXB1/ByJ m 559398.3333 65143.8224 691786.5087 427010.1579
CXB2/ByJ m 399738.2667 65143.8224 532126.4421 267350.0913
CXB3/ByJ m 458901.1 79784.5624 621042.8389 296759.3611
CXB4/ByJ m 773065.2 79784.5624 935206.9389 610923.4611
CXB6/ByJ m 511563.2667 65143.8224 643951.4421 379175.0913
CXB7/ByJ m 585732.2 79784.5624 747873.9389 423590.4611
CXB8/HiAJ m 451309.7333 65143.8224 583697.9087 318921.5579
CXB9/HiAJ m 506293.4 65143.8224 638681.5754 373905.2246
DBA/2J m 255732.525 56416.2051 370384.0481 141081.0019




  GWAS USING LINEAR MIXED MODELS