Project measure / variable:   HMDPpheno6   homo_Ser

ID, description, units MPD:50130   homo_Ser   liver homoserine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   104 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver homoserine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested104 strains
Mean of the strain means73414   None
Median of the strain means50623   None
SD of the strain means± 57482
Coefficient of variation (CV)0.783
Min–max range of strain means9612   –   320926   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 19 168681880202.122 8877993694.8485 2.9362 0.0038
Residuals 31 93732040539.7496 3023614210.9597


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 71468.0 0.0   1   0.0 0.0 71468.0, 71468.0 -0.03
A/J m 36197.0 20118.0   2   14226.0 0.556 21972.0, 50423.0 -0.65
AKR/J m 25523.0 0.0   1   0.0 0.0 25523.0, 25523.0 -0.83
AXB10/PgnJ m 82268.0 0.0   1   0.0 0.0 82268.0, 82268.0 0.15
AXB12/PgnJ m 31064.0 0.0   1   0.0 0.0 31064.0, 31064.0 -0.74
AXB13/PgnJ m 33982.0 0.0   1   0.0 0.0 33982.0, 33982.0 -0.69
AXB15/PgnJ m 87256.0 0.0   1   0.0 0.0 87256.0, 87256.0 0.24
AXB19a/PgnJ m 73542.0 0.0   1   0.0 0.0 73542.0, 73542.0 0.0
AXB19b/PgnJ m 48500.0 26119.0   2   18469.0 0.539 30032.0, 66969.0 -0.43
AXB19/PgnJ m 71993.0 0.0   1   0.0 0.0 71993.0, 71993.0 -0.02
AXB1/PgnJ m 37046.0 0.0   1   0.0 0.0 37046.0, 37046.0 -0.63
AXB23/PgnJ m 20956.0 0.0   1   0.0 0.0 20956.0, 20956.0 -0.91
AXB24/PgnJ m 165685.0 86775.0   2   61359.0 0.524 104326.0, 227044.0 1.61
AXB2/PgnJ m 42572.0 0.0   1   0.0 0.0 42572.0, 42572.0 -0.54
AXB4/PgnJ m 22521.0 0.0   1   0.0 0.0 22521.0, 22521.0 -0.89
AXB5/PgnJ m 130660.0 0.0   1   0.0 0.0 130660.0, 130660.0 1.0
AXB6/PgnJ m 16695.0 0.0   1   0.0 0.0 16695.0, 16695.0 -0.99
BALB/cJ m 28330.0 8048.0   3 4646.0 0.284 21976.0, 37379.0 -0.78
BTBR T+ Itpr3tf/J m 75467.0 0.0   1   0.0 0.0 75467.0, 75467.0 0.04
BUB/BnJ m 25336.0 0.0   1   0.0 0.0 25336.0, 25336.0 -0.84
BXA11/PgnJ m 61170.0 0.0   1   0.0 0.0 61170.0, 61170.0 -0.21
BXA12/PgnJ m 50701.0 0.0   1   0.0 0.0 50701.0, 50701.0 -0.4
BXA13/PgnJ m 71992.0 0.0   1   0.0 0.0 71992.0, 71992.0 -0.02
BXA14/PgnJ m 109039.0 0.0   1   0.0 0.0 109039.0, 109039.0 0.62
BXA16/PgnJ m 208032.0 158262.0   2   111908.0 0.761 96124.0, 319941.0 2.34
BXA1/PgnJ m 26544.0 0.0   1   0.0 0.0 26544.0, 26544.0 -0.82
BXA24/PgnJ m 168174.0 0.0   1   0.0 0.0 168174.0, 168174.0 1.65
BXA25/PgnJ m 158034.0 0.0   1   0.0 0.0 158034.0, 158034.0 1.47
BXA26/PgnJ m 51718.0 0.0   1   0.0 0.0 51718.0, 51718.0 -0.38
BXA2/PgnJ m 42260.0 0.0   1   0.0 0.0 42260.0, 42260.0 -0.54
BXA4/PgnJ m 57321.0 0.0   1   0.0 0.0 57321.0, 57321.0 -0.28
BXA7/PgnJ m 43815.0 0.0   1   0.0 0.0 43815.0, 43815.0 -0.51
BXA8/PgnJ m 30908.0 0.0   1   0.0 0.0 30908.0, 30908.0 -0.74
BXD11/TyJ m 97199.0 0.0   1   0.0 0.0 97199.0, 97199.0 0.41
BXD12/TyJ m 90608.0 0.0   1   0.0 0.0 90608.0, 90608.0 0.3
BXD13/TyJ m 42655.0 0.0   1   0.0 0.0 42655.0, 42655.0 -0.54
BXD14/TyJ m 51522.0 0.0   1   0.0 0.0 51522.0, 51522.0 -0.38
BXD15/TyJ m 140297.0 0.0   1   0.0 0.0 140297.0, 140297.0 1.16
BXD18/TyJ m 108849.0 0.0   1   0.0 0.0 108849.0, 108849.0 0.62
BXD19/TyJ m 187718.0 7320.0   2   5176.0 0.039 182542.0, 192894.0 1.99
BXD1/TyJ m 156412.0 0.0   1   0.0 0.0 156412.0, 156412.0 1.44
BXD20/TyJ m 93120.0 0.0   1   0.0 0.0 93120.0, 93120.0 0.34
BXD21/TyJ m 320926.0 0.0   1   0.0 0.0 320926.0, 320926.0 4.31
BXD22/TyJ m 44103.0 0.0   1   0.0 0.0 44103.0, 44103.0 -0.51
BXD24/TyJ m 178646.0 0.0   1   0.0 0.0 178646.0, 178646.0 1.83
BXD24/TyJ-Cep290rd16/J m 196546.0 0.0   1   0.0 0.0 196546.0, 196546.0 2.14
BXD28/TyJ m 44917.0 6243.0   2   4415.0 0.139 40502.0, 49332.0 -0.5
BXD29-Tlr4lps-2J/J m 163535.0 0.0   1   0.0 0.0 163535.0, 163535.0 1.57
BXD2/TyJ m 67598.0 0.0   1   0.0 0.0 67598.0, 67598.0 -0.1
BXD32/TyJ m 48923.0 0.0   1   0.0 0.0 48923.0, 48923.0 -0.43
BXD33/TyJ m 49711.0 0.0   1   0.0 0.0 49711.0, 49711.0 -0.41
BXD34/TyJ m 43666.0 0.0   1   0.0 0.0 43666.0, 43666.0 -0.52
BXD36/TyJ m 113372.0 0.0   1   0.0 0.0 113372.0, 113372.0 0.7
BXD38/TyJ m 103010.0 0.0   1   0.0 0.0 103010.0, 103010.0 0.51
BXD39/TyJ m 105814.0 0.0   1   0.0 0.0 105814.0, 105814.0 0.56
BXD40/TyJ m 50545.0 0.0   1   0.0 0.0 50545.0, 50545.0 -0.4
BXD42/TyJ m 69763.0 0.0   1   0.0 0.0 69763.0, 69763.0 -0.06
BXD5/TyJ m 92382.0 0.0   1   0.0 0.0 92382.0, 92382.0 0.33
BXD6/TyJ m 58421.0 0.0   1   0.0 0.0 58421.0, 58421.0 -0.26
BXD8/TyJ m 57835.0 0.0   1   0.0 0.0 57835.0, 57835.0 -0.27
BXD9/TyJ m 281831.0 0.0   1   0.0 0.0 281831.0, 281831.0 3.63
BXH10/TyJ m 64673.0 0.0   1   0.0 0.0 64673.0, 64673.0 -0.15
BXH19/TyJ m 116711.0 0.0   1   0.0 0.0 116711.0, 116711.0 0.75
BXH20/KccJ m 73564.0 0.0   1   0.0 0.0 73564.0, 73564.0 0.0
BXH22/KccJ m 126195.0 0.0   1   0.0 0.0 126195.0, 126195.0 0.92
BXH2/TyJ m 38259.0 0.0   1   0.0 0.0 38259.0, 38259.0 -0.61
BXH4/TyJ m 65132.0 12002.0   2   8486.0 0.184 56646.0, 73619.0 -0.14
BXH6/TyJ m 49332.0 0.0   1   0.0 0.0 49332.0, 49332.0 -0.42
BXH7/TyJ m 62762.0 0.0   1   0.0 0.0 62762.0, 62762.0 -0.19
BXH8/TyJ m 49332.0 0.0   1   0.0 0.0 49332.0, 49332.0 -0.42
BXH9/TyJ m 49568.0 0.0   1   0.0 0.0 49568.0, 49568.0 -0.41
C3H/HeJ m 49396.0 22649.0   2   16015.0 0.459 33381.0, 65411.0 -0.42
C57BL/6J m 30941.0 10564.0   5 4724.0 0.341 20672.0, 45533.0 -0.74
C57L/J m 16807.0 0.0   1   0.0 0.0 16807.0, 16807.0 -0.98
C58/J m 43642.0 0.0   1   0.0 0.0 43642.0, 43642.0 -0.52
CAST/EiJ m 155078.0 0.0   1   0.0 0.0 155078.0, 155078.0 1.42
CBA/J m 29035.0 0.0   1   0.0 0.0 29035.0, 29035.0 -0.77
CE/J m 116390.0 0.0   1   0.0 0.0 116390.0, 116390.0 0.75
CXB11/HiAJ m 64173.0 49115.0   2   34729.0 0.765 29444.0, 98902.0 -0.16
CXB12/HiAJ m 29247.0 6912.0   2   4888.0 0.236 24359.0, 34134.0 -0.77
CXB13/HiAJ m 47302.0 29192.0   3 16854.0 0.617 19459.0, 77678.0 -0.45
CXB1/ByJ m 48174.0 19513.0   3 11266.0 0.405 32646.0, 70077.0 -0.44
CXB2/ByJ m 9612.0 0.0   1   0.0 0.0 9612.0, 9612.0 -1.11
CXB3/ByJ m 30708.0 8531.0   2   6033.0 0.278 24675.0, 36740.0 -0.74
CXB4/ByJ m 37935.0 10128.0   2   7161.0 0.267 30774.0, 45096.0 -0.62
CXB6/ByJ m 32026.0 9277.0   3 5356.0 0.29 21334.0, 37937.0 -0.72
CXB7/ByJ m 22646.0 0.0   1   0.0 0.0 22646.0, 22646.0 -0.88
CXB8/HiAJ m 23838.0 4445.0   3 2567.0 0.186 18901.0, 27524.0 -0.86
CXB9/HiAJ m 34609.0 2299.0   3 1327.0 0.0664 32893.0, 37221.0 -0.68
DBA/2J m 171023.0 133441.0   4 66720.0 0.78 47140.0, 330951.0 1.7
FVB/NJ m 90288.0 0.0   1   0.0 0.0 90288.0, 90288.0 0.29
I/LnJ m 19855.0 0.0   1   0.0 0.0 19855.0, 19855.0 -0.93
KK/HlJ m 23442.0 0.0   1   0.0 0.0 23442.0, 23442.0 -0.87
LG/J m 43181.0 0.0   1   0.0 0.0 43181.0, 43181.0 -0.53
LP/J m 48952.0 0.0   1   0.0 0.0 48952.0, 48952.0 -0.43
MA/MyJ m 18120.0 0.0   1   0.0 0.0 18120.0, 18120.0 -0.96
NOD/ShiLtJ m 20354.0 0.0   1   0.0 0.0 20354.0, 20354.0 -0.92
NON/ShiLtJ m 27603.0 0.0   1   0.0 0.0 27603.0, 27603.0 -0.8
NZW/LacJ m 55586.0 0.0   1   0.0 0.0 55586.0, 55586.0 -0.31
PL/J m 29295.0 0.0   1   0.0 0.0 29295.0, 29295.0 -0.77
SEA/GnJ m 33150.0 0.0   1   0.0 0.0 33150.0, 33150.0 -0.7
SJL/J m 21936.0 0.0   1   0.0 0.0 21936.0, 21936.0 -0.9
SM/J m 66678.0 0.0   1   0.0 0.0 66678.0, 66678.0 -0.12
SWR/J m 181859.0 0.0   1   0.0 0.0 181859.0, 181859.0 1.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 36197.35 38881.9638 115497.6379 0.0
AXB19b/PgnJ m 48500.2 38881.9638 127800.4879 0.0
AXB24/PgnJ m 165684.95 38881.9638 244985.2379 86384.6621
BALB/cJ m 28329.7 31746.9905 93078.1139 0.0
BXA16/PgnJ m 208032.35 38881.9638 287332.6379 128732.0621
BXD19/TyJ m 187718.0 38881.9638 267018.2879 108417.7121
BXD28/TyJ m 44916.9 38881.9638 124217.1879 0.0
BXH4/TyJ m 65132.45 38881.9638 144432.7379 0.0
C3H/HeJ m 49396.15 38881.9638 128696.4379 0.0
C57BL/6J m 30940.72 24591.1131 81094.6258 0.0
CXB11/HiAJ m 64173.0 38881.9638 143473.2879 0.0
CXB12/HiAJ m 29246.65 38881.9638 108546.9379 0.0
CXB13/HiAJ m 47302.4667 31746.9905 112050.8806 0.0
CXB1/ByJ m 48173.5333 31746.9905 112921.9473 0.0
CXB3/ByJ m 30707.55 38881.9638 110007.8379 0.0
CXB4/ByJ m 37935.1 38881.9638 117235.3879 0.0
CXB6/ByJ m 32026.4333 31746.9905 96774.8473 0.0
CXB8/HiAJ m 23838.1333 31746.9905 88586.5473 0.0
CXB9/HiAJ m 34608.8 31746.9905 99357.2139 0.0
DBA/2J m 171023.1 27493.7002 227096.8713 114949.3287




  GWAS USING LINEAR MIXED MODELS