Project measure / variable:   HMDPpheno6   hydroxy_Pro

ID, description, units MPD:50157   hydroxy_Pro   liver trans-4-hydroxyproline (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   103 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver trans-4-hydroxyproline (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested103 strains
Mean of the strain means177252   None
Median of the strain means152709   None
SD of the strain means± 90931
Coefficient of variation (CV)0.513
Min–max range of strain means43140   –   550584   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 231784461263.84 11037355298.2781 1.9542 0.0399
Residuals 34 192028030421.154 5647883247.681


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 148362.0 0.0   1   0.0 0.0 148362.0, 148362.0 -0.32
A/J m 149220.0 7288.0   2   5153.0 0.0488 144066.0, 154373.0 -0.31
AKR/J m 155349.0 0.0   1   0.0 0.0 155349.0, 155349.0 -0.24
AXB10/PgnJ m 152709.0 0.0   1   0.0 0.0 152709.0, 152709.0 -0.27
AXB12/PgnJ m 114279.0 0.0   1   0.0 0.0 114279.0, 114279.0 -0.69
AXB13/PgnJ m 133869.0 0.0   1   0.0 0.0 133869.0, 133869.0 -0.48
AXB15/PgnJ m 183770.0 0.0   1   0.0 0.0 183770.0, 183770.0 0.07
AXB19a/PgnJ m 115169.0 0.0   1   0.0 0.0 115169.0, 115169.0 -0.68
AXB19b/PgnJ m 188866.0 26024.0   2   18402.0 0.138 170464.0, 207268.0 0.13
AXB19/PgnJ m 106710.0 0.0   1   0.0 0.0 106710.0, 106710.0 -0.78
AXB1/PgnJ m 108046.0 0.0   1   0.0 0.0 108046.0, 108046.0 -0.76
AXB23/PgnJ m 150166.0 0.0   1   0.0 0.0 150166.0, 150166.0 -0.3
AXB24/PgnJ m 134972.0 20092.0   2   14207.0 0.149 120764.0, 149179.0 -0.46
AXB2/PgnJ m 313174.0 0.0   1   0.0 0.0 313174.0, 313174.0 1.49
AXB4/PgnJ m 116724.0 0.0   1   0.0 0.0 116724.0, 116724.0 -0.67
AXB5/PgnJ m 150622.0 0.0   1   0.0 0.0 150622.0, 150622.0 -0.29
AXB6/PgnJ m 237127.0 0.0   1   0.0 0.0 237127.0, 237127.0 0.66
AXB8/PgnJ m 88136.0 0.0   1   0.0 0.0 88136.0, 88136.0 -0.98
BALB/cJ m 298175.0 117283.0   3 67713.0 0.393 199369.0, 427786.0 1.33
BTBR T+ Itpr3tf/J m 243136.0 0.0   1   0.0 0.0 243136.0, 243136.0 0.72
BUB/BnJ m 221990.0 0.0   1   0.0 0.0 221990.0, 221990.0 0.49
BXA11/PgnJ m 214472.0 0.0   1   0.0 0.0 214472.0, 214472.0 0.41
BXA12/PgnJ m 149936.0 0.0   1   0.0 0.0 149936.0, 149936.0 -0.3
BXA13/PgnJ m 394690.0 0.0   1   0.0 0.0 394690.0, 394690.0 2.39
BXA14/PgnJ m 541276.0 0.0   1   0.0 0.0 541276.0, 541276.0 4.0
BXA16/PgnJ m 122551.0 34562.0   2   24439.0 0.282 98112.0, 146990.0 -0.6
BXA1/PgnJ m 76050.0 0.0   1   0.0 0.0 76050.0, 76050.0 -1.11
BXA24/PgnJ m 279636.0 0.0   1   0.0 0.0 279636.0, 279636.0 1.13
BXA25/PgnJ m 131317.0 0.0   1   0.0 0.0 131317.0, 131317.0 -0.51
BXA26/PgnJ m 268109.0 0.0   1   0.0 0.0 268109.0, 268109.0 1.0
BXA2/PgnJ m 173939.0 0.0   1   0.0 0.0 173939.0, 173939.0 -0.04
BXA4/PgnJ m 159296.0 0.0   1   0.0 0.0 159296.0, 159296.0 -0.2
BXA7/PgnJ m 281737.0 0.0   1   0.0 0.0 281737.0, 281737.0 1.15
BXA8/PgnJ m 124540.0 0.0   1   0.0 0.0 124540.0, 124540.0 -0.58
BXD11/TyJ m 132982.0 0.0   1   0.0 0.0 132982.0, 132982.0 -0.49
BXD12/TyJ m 382268.0 0.0   1   0.0 0.0 382268.0, 382268.0 2.25
BXD13/TyJ m 119307.0 0.0   1   0.0 0.0 119307.0, 119307.0 -0.64
BXD14/TyJ m 200451.0 0.0   1   0.0 0.0 200451.0, 200451.0 0.26
BXD15/TyJ m 152320.0 0.0   1   0.0 0.0 152320.0, 152320.0 -0.27
BXD18/TyJ m 268375.0 0.0   1   0.0 0.0 268375.0, 268375.0 1.0
BXD19/TyJ m 132321.0 1031.0   2   729.0 0.00779 131593.0, 133050.0 -0.49
BXD1/TyJ m 123546.0 0.0   1   0.0 0.0 123546.0, 123546.0 -0.59
BXD20/TyJ m 137962.0 0.0   1   0.0 0.0 137962.0, 137962.0 -0.43
BXD21/TyJ m 94364.0 0.0   1   0.0 0.0 94364.0, 94364.0 -0.91
BXD22/TyJ m 76471.0 0.0   1   0.0 0.0 76471.0, 76471.0 -1.11
BXD24/TyJ m 86863.0 0.0   1   0.0 0.0 86863.0, 86863.0 -0.99
BXD24/TyJ-Cep290rd16/J m 43140.0 0.0   1   0.0 0.0 43140.0, 43140.0 -1.47
BXD28/TyJ m 201659.0 31665.0   2   22391.0 0.157 179268.0, 224050.0 0.27
BXD29-Tlr4lps-2J/J m 185401.0 0.0   1   0.0 0.0 185401.0, 185401.0 0.09
BXD2/TyJ m 199606.0 0.0   1   0.0 0.0 199606.0, 199606.0 0.25
BXD32/TyJ m 136705.0 0.0   1   0.0 0.0 136705.0, 136705.0 -0.45
BXD33/TyJ m 206692.0 0.0   1   0.0 0.0 206692.0, 206692.0 0.32
BXD34/TyJ m 93548.0 0.0   1   0.0 0.0 93548.0, 93548.0 -0.92
BXD36/TyJ m 199209.0 0.0   1   0.0 0.0 199209.0, 199209.0 0.24
BXD38/TyJ m 264435.0 0.0   1   0.0 0.0 264435.0, 264435.0 0.96
BXD39/TyJ m 84941.0 0.0   1   0.0 0.0 84941.0, 84941.0 -1.02
BXD40/TyJ m 114230.0 0.0   1   0.0 0.0 114230.0, 114230.0 -0.69
BXD42/TyJ m 112762.0 0.0   1   0.0 0.0 112762.0, 112762.0 -0.71
BXD5/TyJ m 88733.0 0.0   1   0.0 0.0 88733.0, 88733.0 -0.97
BXD6/TyJ m 226153.0 0.0   1   0.0 0.0 226153.0, 226153.0 0.54
BXD8/TyJ m 155349.0 0.0   1   0.0 0.0 155349.0, 155349.0 -0.24
BXD9/TyJ m 132880.0 0.0   1   0.0 0.0 132880.0, 132880.0 -0.49
BXH19/TyJ m 114897.0 0.0   1   0.0 0.0 114897.0, 114897.0 -0.69
BXH20/KccJ m 155349.0 0.0   1   0.0 0.0 155349.0, 155349.0 -0.24
BXH22/KccJ m 100458.0 0.0   1   0.0 0.0 100458.0, 100458.0 -0.84
BXH2/TyJ m 103485.0 0.0   1   0.0 0.0 103485.0, 103485.0 -0.81
BXH4/TyJ m 146698.0 13407.0   2   9480.0 0.0914 137218.0, 156178.0 -0.34
BXH6/TyJ m 124195.0 0.0   1   0.0 0.0 124195.0, 124195.0 -0.58
BXH7/TyJ m 172643.0 0.0   1   0.0 0.0 172643.0, 172643.0 -0.05
BXH8/TyJ m 162298.0 0.0   1   0.0 0.0 162298.0, 162298.0 -0.16
C3H/HeJ m 135286.0 33021.0   2   23350.0 0.244 111936.0, 158635.0 -0.46
C57BL/6J m 237005.0 96596.0   5 43199.0 0.408 147893.0, 361826.0 0.66
C57L/J m 97639.0 0.0   1   0.0 0.0 97639.0, 97639.0 -0.88
CAST/EiJ m 550584.0 0.0   1   0.0 0.0 550584.0, 550584.0 4.11
CBA/J m 154520.0 0.0   1   0.0 0.0 154520.0, 154520.0 -0.25
CE/J m 143662.0 0.0   1   0.0 0.0 143662.0, 143662.0 -0.37
CXB11/HiAJ m 159338.0 14624.0   2   10340.0 0.0918 148998.0, 169678.0 -0.2
CXB12/HiAJ m 233633.0 38104.0   2   26944.0 0.163 206690.0, 260577.0 0.62
CXB13/HiAJ m 155556.0 16117.0   3 9305.0 0.104 140556.0, 172596.0 -0.24
CXB1/ByJ m 159559.0 67495.0   3 38968.0 0.423 86926.0, 220348.0 -0.19
CXB2/ByJ m 228681.0 47459.0   3 27401.0 0.208 179718.0, 274478.0 0.57
CXB3/ByJ m 191321.0 65015.0   2   45972.0 0.34 145349.0, 237294.0 0.15
CXB4/ByJ m 121222.0 40263.0   2   28470.0 0.332 92752.0, 149692.0 -0.62
CXB6/ByJ m 372969.0 209050.0   3 120695.0 0.561 226296.0, 612340.0 2.15
CXB7/ByJ m 115596.0 18845.0   2   13326.0 0.163 102270.0, 128921.0 -0.68
CXB8/HiAJ m 151671.0 31417.0   3 18139.0 0.207 120626.0, 183447.0 -0.28
CXB9/HiAJ m 198446.0 62427.0   3 36042.0 0.315 154061.0, 269828.0 0.23
DBA/2J m 238989.0 33739.0   4 16869.0 0.141 193408.0, 271747.0 0.68
FVB/NJ m 225640.0 0.0   1   0.0 0.0 225640.0, 225640.0 0.53
I/LnJ m 128959.0 0.0   1   0.0 0.0 128959.0, 128959.0 -0.53
KK/HlJ m 185642.0 0.0   1   0.0 0.0 185642.0, 185642.0 0.09
LG/J m 101749.0 0.0   1   0.0 0.0 101749.0, 101749.0 -0.83
LP/J m 112441.0 0.0   1   0.0 0.0 112441.0, 112441.0 -0.71
MA/MyJ m 178568.0 0.0   1   0.0 0.0 178568.0, 178568.0 0.01
NOD/ShiLtJ m 152062.0 0.0   1   0.0 0.0 152062.0, 152062.0 -0.28
NON/ShiLtJ m 162673.0 0.0   1   0.0 0.0 162673.0, 162673.0 -0.16
NZW/LacJ m 173427.0 0.0   1   0.0 0.0 173427.0, 173427.0 -0.04
PL/J m 128756.0 0.0   1   0.0 0.0 128756.0, 128756.0 -0.53
RIIIS/J m 212740.0 0.0   1   0.0 0.0 212740.0, 212740.0 0.39
SEA/GnJ m 167582.0 0.0   1   0.0 0.0 167582.0, 167582.0 -0.11
SJL/J m 114851.0 0.0   1   0.0 0.0 114851.0, 114851.0 -0.69
SM/J m 531938.0 0.0   1   0.0 0.0 531938.0, 531938.0 3.9
SWR/J m 173464.0 0.0   1   0.0 0.0 173464.0, 173464.0 -0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 149219.6 53140.7718 257214.6416 41224.5584
AXB19b/PgnJ m 188866.15 53140.7718 296861.1916 80871.1084
AXB24/PgnJ m 134971.6 53140.7718 242966.6416 26976.5584
BALB/cJ m 298175.0333 43389.2585 386352.6156 209997.4511
BXA16/PgnJ m 122550.8 53140.7718 230545.8416 14555.7584
BXD19/TyJ m 132321.35 53140.7718 240316.3916 24326.3084
BXD28/TyJ m 201659.2 53140.7718 309654.2416 93664.1584
BXH4/TyJ m 146698.0 53140.7718 254693.0416 38702.9584
C3H/HeJ m 135285.8 53140.7718 243280.8416 27290.7584
C57BL/6J m 237004.66 33609.1751 305306.7215 168702.5985
CXB11/HiAJ m 159338.0 53140.7718 267333.0416 51342.9584
CXB12/HiAJ m 233633.4 53140.7718 341628.4416 125638.3584
CXB13/HiAJ m 155556.2 43389.2585 243733.7823 67378.6177
CXB1/ByJ m 159559.0 43389.2585 247736.5823 71381.4177
CXB2/ByJ m 228681.3333 43389.2585 316858.9156 140503.7511
CXB3/ByJ m 191321.1 53140.7718 299316.1416 83326.0584
CXB4/ByJ m 121221.9 53140.7718 229216.9416 13226.8584
CXB6/ByJ m 372969.1667 43389.2585 461146.7489 284791.5844
CXB7/ByJ m 115595.65 53140.7718 223590.6916 7600.6084
CXB8/HiAJ m 151671.1 43389.2585 239848.6823 63493.5177
CXB9/HiAJ m 198445.9667 43389.2585 286623.5489 110268.3844
DBA/2J m 238989.0 37576.2001 315353.0263 162624.9737




  GWAS USING LINEAR MIXED MODELS