Project measure / variable:   HMDPpheno6   acetyl_Ala

ID, description, units MPD:50106   acetyl_Ala   liver N-acetylalanine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   104 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver N-acetylalanine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested104 strains
Mean of the strain means22066   None
Median of the strain means21504   None
SD of the strain means± 5723
Coefficient of variation (CV)0.259
Min–max range of strain means12450   –   38285   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 2273201409.3967 113660070.4698 8.6835 < 0.0001
Residuals 33 431942111.9003 13089154.9061


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 21889.0 0.0   1   0.0 0.0 21889.0, 21889.0 -0.03
A/J m 19783.0 1350.0   2   955.0 0.0683 18828.0, 20738.0 -0.4
AKR/J m 15651.0 0.0   1   0.0 0.0 15651.0, 15651.0 -1.12
AXB10/PgnJ m 22771.0 0.0   1   0.0 0.0 22771.0, 22771.0 0.12
AXB12/PgnJ m 18374.0 0.0   1   0.0 0.0 18374.0, 18374.0 -0.65
AXB13/PgnJ m 22910.0 0.0   1   0.0 0.0 22910.0, 22910.0 0.15
AXB15/PgnJ m 19598.0 0.0   1   0.0 0.0 19598.0, 19598.0 -0.43
AXB19a/PgnJ m 24895.0 0.0   1   0.0 0.0 24895.0, 24895.0 0.49
AXB19b/PgnJ m 30906.0 4961.0   2   3508.0 0.161 27398.0, 34414.0 1.54
AXB19/PgnJ m 24973.0 0.0   1   0.0 0.0 24973.0, 24973.0 0.51
AXB1/PgnJ m 18152.0 0.0   1   0.0 0.0 18152.0, 18152.0 -0.68
AXB23/PgnJ m 21776.0 0.0   1   0.0 0.0 21776.0, 21776.0 -0.05
AXB24/PgnJ m 19929.0 0.0   1   0.0 0.0 19929.0, 19929.0 -0.37
AXB2/PgnJ m 20431.0 0.0   1   0.0 0.0 20431.0, 20431.0 -0.29
AXB4/PgnJ m 18435.0 0.0   1   0.0 0.0 18435.0, 18435.0 -0.63
AXB5/PgnJ m 17492.0 0.0   1   0.0 0.0 17492.0, 17492.0 -0.8
AXB6/PgnJ m 23209.0 0.0   1   0.0 0.0 23209.0, 23209.0 0.2
AXB8/PgnJ m 28761.0 0.0   1   0.0 0.0 28761.0, 28761.0 1.17
BALB/cJ m 25159.0 384.0   3 222.0 0.0153 24797.0, 25562.0 0.54
BTBR T+ Itpr3tf/J m 21878.0 0.0   1   0.0 0.0 21878.0, 21878.0 -0.03
BUB/BnJ m 27587.0 0.0   1   0.0 0.0 27587.0, 27587.0 0.96
BXA11/PgnJ m 21557.0 0.0   1   0.0 0.0 21557.0, 21557.0 -0.09
BXA12/PgnJ m 19866.0 0.0   1   0.0 0.0 19866.0, 19866.0 -0.38
BXA13/PgnJ m 27176.0 0.0   1   0.0 0.0 27176.0, 27176.0 0.89
BXA14/PgnJ m 17067.0 0.0   1   0.0 0.0 17067.0, 17067.0 -0.87
BXA16/PgnJ m 23014.0 1199.0   2   848.0 0.0521 22167.0, 23862.0 0.17
BXA1/PgnJ m 25373.0 0.0   1   0.0 0.0 25373.0, 25373.0 0.58
BXA24/PgnJ m 30240.0 0.0   1   0.0 0.0 30240.0, 30240.0 1.43
BXA25/PgnJ m 16430.0 0.0   1   0.0 0.0 16430.0, 16430.0 -0.98
BXA26/PgnJ m 30712.0 0.0   1   0.0 0.0 30712.0, 30712.0 1.51
BXA2/PgnJ m 21912.0 0.0   1   0.0 0.0 21912.0, 21912.0 -0.03
BXA7/PgnJ m 27157.0 0.0   1   0.0 0.0 27157.0, 27157.0 0.89
BXD11/TyJ m 21213.0 0.0   1   0.0 0.0 21213.0, 21213.0 -0.15
BXD12/TyJ m 25186.0 0.0   1   0.0 0.0 25186.0, 25186.0 0.55
BXD13/TyJ m 16542.0 0.0   1   0.0 0.0 16542.0, 16542.0 -0.97
BXD14/TyJ m 24270.0 0.0   1   0.0 0.0 24270.0, 24270.0 0.39
BXD15/TyJ m 20527.0 0.0   1   0.0 0.0 20527.0, 20527.0 -0.27
BXD18/TyJ m 16907.0 0.0   1   0.0 0.0 16907.0, 16907.0 -0.9
BXD19/TyJ m 20462.0 5507.0   2   3894.0 0.269 16568.0, 24356.0 -0.28
BXD1/TyJ m 24642.0 0.0   1   0.0 0.0 24642.0, 24642.0 0.45
BXD20/TyJ m 14000.0 0.0   1   0.0 0.0 14000.0, 14000.0 -1.41
BXD21/TyJ m 16254.0 0.0   1   0.0 0.0 16254.0, 16254.0 -1.02
BXD22/TyJ m 19778.0 0.0   1   0.0 0.0 19778.0, 19778.0 -0.4
BXD24/TyJ m 12711.0 0.0   1   0.0 0.0 12711.0, 12711.0 -1.63
BXD24/TyJ-Cep290rd16/J m 12991.0 0.0   1   0.0 0.0 12991.0, 12991.0 -1.59
BXD28/TyJ m 17061.0 1971.0   2   1394.0 0.116 15667.0, 18455.0 -0.87
BXD29-Tlr4lps-2J/J m 22330.0 0.0   1   0.0 0.0 22330.0, 22330.0 0.05
BXD2/TyJ m 28427.0 0.0   1   0.0 0.0 28427.0, 28427.0 1.11
BXD32/TyJ m 22941.0 0.0   1   0.0 0.0 22941.0, 22941.0 0.15
BXD33/TyJ m 22493.0 0.0   1   0.0 0.0 22493.0, 22493.0 0.07
BXD34/TyJ m 19158.0 0.0   1   0.0 0.0 19158.0, 19158.0 -0.51
BXD36/TyJ m 21972.0 0.0   1   0.0 0.0 21972.0, 21972.0 -0.02
BXD38/TyJ m 14511.0 0.0   1   0.0 0.0 14511.0, 14511.0 -1.32
BXD39/TyJ m 24344.0 0.0   1   0.0 0.0 24344.0, 24344.0 0.4
BXD40/TyJ m 17718.0 0.0   1   0.0 0.0 17718.0, 17718.0 -0.76
BXD42/TyJ m 12450.0 0.0   1   0.0 0.0 12450.0, 12450.0 -1.68
BXD5/TyJ m 15364.0 0.0   1   0.0 0.0 15364.0, 15364.0 -1.17
BXD6/TyJ m 14388.0 0.0   1   0.0 0.0 14388.0, 14388.0 -1.34
BXD8/TyJ m 19579.0 0.0   1   0.0 0.0 19579.0, 19579.0 -0.43
BXD9/TyJ m 15707.0 0.0   1   0.0 0.0 15707.0, 15707.0 -1.11
BXH10/TyJ m 19614.0 0.0   1   0.0 0.0 19614.0, 19614.0 -0.43
BXH19/TyJ m 16959.0 0.0   1   0.0 0.0 16959.0, 16959.0 -0.89
BXH20/KccJ m 20786.0 0.0   1   0.0 0.0 20786.0, 20786.0 -0.22
BXH22/KccJ m 20740.0 0.0   1   0.0 0.0 20740.0, 20740.0 -0.23
BXH2/TyJ m 21749.0 0.0   1   0.0 0.0 21749.0, 21749.0 -0.06
BXH4/TyJ m 15193.0 1433.0   2   1013.0 0.0943 14180.0, 16206.0 -1.2
BXH6/TyJ m 20871.0 0.0   1   0.0 0.0 20871.0, 20871.0 -0.21
BXH7/TyJ m 14061.0 0.0   1   0.0 0.0 14061.0, 14061.0 -1.4
BXH8/TyJ m 21451.0 0.0   1   0.0 0.0 21451.0, 21451.0 -0.11
BXH9/TyJ m 28524.0 0.0   1   0.0 0.0 28524.0, 28524.0 1.13
C3H/HeJ m 23015.0 7781.0   2   5502.0 0.338 17513.0, 28517.0 0.17
C57BL/6J m 34996.0 4032.0   5 1803.0 0.115 30990.0, 39707.0 2.26
C57L/J m 14797.0 0.0   1   0.0 0.0 14797.0, 14797.0 -1.27
C58/J m 31446.0 0.0   1   0.0 0.0 31446.0, 31446.0 1.64
CAST/EiJ m 18652.0 0.0   1   0.0 0.0 18652.0, 18652.0 -0.6
CBA/J m 16775.0 0.0   1   0.0 0.0 16775.0, 16775.0 -0.92
CE/J m 27454.0 0.0   1   0.0 0.0 27454.0, 27454.0 0.94
CXB11/HiAJ m 23933.0 4330.0   2   3061.0 0.181 20872.0, 26995.0 0.33
CXB12/HiAJ m 38285.0 3326.0   2   2352.0 0.0869 35933.0, 40637.0 2.83
CXB13/HiAJ m 25480.0 582.0   3 336.0 0.0228 24830.0, 25951.0 0.6
CXB1/ByJ m 25747.0 2661.0   3 1536.0 0.103 23103.0, 28424.0 0.64
CXB2/ByJ m 30577.0 4692.0   3 2709.0 0.153 26668.0, 35780.0 1.49
CXB3/ByJ m 30524.0 3923.0   2   2774.0 0.129 27750.0, 33297.0 1.48
CXB4/ByJ m 25554.0 2908.0   2   2056.0 0.114 23498.0, 27610.0 0.61
CXB6/ByJ m 34635.0 3714.0   3 2145.0 0.107 32160.0, 38906.0 2.2
CXB7/ByJ m 34321.0 4515.0   2   3193.0 0.132 31128.0, 37514.0 2.14
CXB8/HiAJ m 37458.0 2695.0   3 1556.0 0.072 34627.0, 39993.0 2.69
CXB9/HiAJ m 34022.0 2102.0   3 1214.0 0.0618 32534.0, 36428.0 2.09
DBA/2J m 21672.0 4400.0   4 2200.0 0.203 15984.0, 26644.0 -0.07
FVB/NJ m 19294.0 0.0   1   0.0 0.0 19294.0, 19294.0 -0.48
I/LnJ m 21739.0 0.0   1   0.0 0.0 21739.0, 21739.0 -0.06
KK/HlJ m 19454.0 0.0   1   0.0 0.0 19454.0, 19454.0 -0.46
LG/J m 13316.0 0.0   1   0.0 0.0 13316.0, 13316.0 -1.53
LP/J m 14682.0 0.0   1   0.0 0.0 14682.0, 14682.0 -1.29
MA/MyJ m 17197.0 0.0   1   0.0 0.0 17197.0, 17197.0 -0.85
NOD/ShiLtJ m 26397.0 0.0   1   0.0 0.0 26397.0, 26397.0 0.76
NON/ShiLtJ m 29470.0 0.0   1   0.0 0.0 29470.0, 29470.0 1.29
NZW/LacJ m 17743.0 0.0   1   0.0 0.0 17743.0, 17743.0 -0.76
PL/J m 23217.0 0.0   1   0.0 0.0 23217.0, 23217.0 0.2
RIIIS/J m 18958.0 0.0   1   0.0 0.0 18958.0, 18958.0 -0.54
SEA/GnJ m 20934.0 0.0   1   0.0 0.0 20934.0, 20934.0 -0.2
SJL/J m 16542.0 0.0   1   0.0 0.0 16542.0, 16542.0 -0.97
SM/J m 20017.0 0.0   1   0.0 0.0 20017.0, 20017.0 -0.36
SWR/J m 27647.0 0.0   1   0.0 0.0 27647.0, 27647.0 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 19783.25 2558.2372 24988.0227 14578.4773
AXB19b/PgnJ m 30905.55 2558.2372 36110.3227 25700.7773
BALB/cJ m 25158.7333 2088.7919 29408.4124 20909.0542
BXA16/PgnJ m 23014.5 2558.2372 28219.2727 17809.7273
BXD19/TyJ m 20461.95 2558.2372 25666.7227 15257.1773
BXD28/TyJ m 17061.05 2558.2372 22265.8227 11856.2773
BXH4/TyJ m 15193.25 2558.2372 20398.0227 9988.4773
C3H/HeJ m 23015.1 2558.2372 28219.8727 17810.3273
C57BL/6J m 34995.56 1617.9713 38287.3473 31703.7727
CXB11/HiAJ m 23933.35 2558.2372 29138.1227 18728.5773
CXB12/HiAJ m 38284.8 2558.2372 43489.5727 33080.0273
CXB13/HiAJ m 25480.0333 2088.7919 29729.7124 21230.3542
CXB1/ByJ m 25746.6667 2088.7919 29996.3458 21496.9876
CXB2/ByJ m 30576.7 2088.7919 34826.3791 26327.0209
CXB3/ByJ m 30523.6 2558.2372 35728.3727 25318.8273
CXB4/ByJ m 25554.3 2558.2372 30759.0727 20349.5273
CXB6/ByJ m 34634.8333 2088.7919 38884.5124 30385.1542
CXB7/ByJ m 34320.95 2558.2372 39525.7227 29116.1773
CXB8/HiAJ m 37458.5 2088.7919 41708.1791 33208.8209
CXB9/HiAJ m 34022.4333 2088.7919 38272.1124 29772.7542
DBA/2J m 21671.8 1808.9469 25352.1301 17991.4699




  GWAS USING LINEAR MIXED MODELS