Project measure / variable:   HMDPpheno6   Me_glutathione

ID, description, units MPD:50124   Me_glutathione   liver S-methylglutathione (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver S-methylglutathione (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means167139   None
Median of the strain means158772   None
SD of the strain means± 73855
Coefficient of variation (CV)0.442
Min–max range of strain means41779   –   612675   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 138034647188.86 6573078437.5648 3.2374 0.0011
Residuals 34 69032486725.4284 2030367256.6302


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 233034.0 0.0   1   0.0 0.0 233034.0, 233034.0 0.89
A/J m 220344.0 116806.0   2   82594.0 0.53 137750.0, 302938.0 0.72
AKR/J m 176682.0 0.0   1   0.0 0.0 176682.0, 176682.0 0.13
AXB10/PgnJ m 127838.0 0.0   1   0.0 0.0 127838.0, 127838.0 -0.53
AXB12/PgnJ m 209218.0 0.0   1   0.0 0.0 209218.0, 209218.0 0.57
AXB13/PgnJ m 178389.0 0.0   1   0.0 0.0 178389.0, 178389.0 0.15
AXB15/PgnJ m 273383.0 0.0   1   0.0 0.0 273383.0, 273383.0 1.44
AXB19a/PgnJ m 148671.0 0.0   1   0.0 0.0 148671.0, 148671.0 -0.25
AXB19b/PgnJ m 124713.0 11669.0   2   8251.0 0.0936 116462.0, 132965.0 -0.57
AXB19/PgnJ m 134807.0 0.0   1   0.0 0.0 134807.0, 134807.0 -0.44
AXB1/PgnJ m 41779.0 0.0   1   0.0 0.0 41779.0, 41779.0 -1.7
AXB23/PgnJ m 189147.0 0.0   1   0.0 0.0 189147.0, 189147.0 0.3
AXB24/PgnJ m 217902.0 70394.0   2   49776.0 0.323 168126.0, 267678.0 0.69
AXB2/PgnJ m 161358.0 0.0   1   0.0 0.0 161358.0, 161358.0 -0.08
AXB4/PgnJ m 139746.0 0.0   1   0.0 0.0 139746.0, 139746.0 -0.37
AXB5/PgnJ m 206013.0 0.0   1   0.0 0.0 206013.0, 206013.0 0.53
AXB6/PgnJ m 299621.0 0.0   1   0.0 0.0 299621.0, 299621.0 1.79
AXB8/PgnJ m 158512.0 0.0   1   0.0 0.0 158512.0, 158512.0 -0.12
BALB/cJ m 264541.0 10439.0   3 6027.0 0.0395 254047.0, 274923.0 1.32
BTBR T+ Itpr3tf/J m 113993.0 0.0   1   0.0 0.0 113993.0, 113993.0 -0.72
BUB/BnJ m 135945.0 0.0   1   0.0 0.0 135945.0, 135945.0 -0.42
BXA11/PgnJ m 200566.0 0.0   1   0.0 0.0 200566.0, 200566.0 0.45
BXA12/PgnJ m 127427.0 0.0   1   0.0 0.0 127427.0, 127427.0 -0.54
BXA13/PgnJ m 209812.0 0.0   1   0.0 0.0 209812.0, 209812.0 0.58
BXA14/PgnJ m 612675.0 0.0   1   0.0 0.0 612675.0, 612675.0 6.03
BXA16/PgnJ m 159656.0 35852.0   2   25351.0 0.225 134305.0, 185007.0 -0.1
BXA1/PgnJ m 156731.0 0.0   1   0.0 0.0 156731.0, 156731.0 -0.14
BXA24/PgnJ m 201787.0 0.0   1   0.0 0.0 201787.0, 201787.0 0.47
BXA25/PgnJ m 100304.0 0.0   1   0.0 0.0 100304.0, 100304.0 -0.9
BXA26/PgnJ m 157450.0 0.0   1   0.0 0.0 157450.0, 157450.0 -0.13
BXA2/PgnJ m 272604.0 0.0   1   0.0 0.0 272604.0, 272604.0 1.43
BXA4/PgnJ m 126159.0 0.0   1   0.0 0.0 126159.0, 126159.0 -0.55
BXA7/PgnJ m 141481.0 0.0   1   0.0 0.0 141481.0, 141481.0 -0.35
BXA8/PgnJ m 198443.0 0.0   1   0.0 0.0 198443.0, 198443.0 0.42
BXD11/TyJ m 159031.0 0.0   1   0.0 0.0 159031.0, 159031.0 -0.11
BXD12/TyJ m 223313.0 0.0   1   0.0 0.0 223313.0, 223313.0 0.76
BXD13/TyJ m 137831.0 0.0   1   0.0 0.0 137831.0, 137831.0 -0.4
BXD14/TyJ m 183680.0 0.0   1   0.0 0.0 183680.0, 183680.0 0.22
BXD15/TyJ m 112777.0 0.0   1   0.0 0.0 112777.0, 112777.0 -0.74
BXD18/TyJ m 145130.0 0.0   1   0.0 0.0 145130.0, 145130.0 -0.3
BXD19/TyJ m 164516.0 7561.0   2   5346.0 0.046 159170.0, 169863.0 -0.04
BXD1/TyJ m 66320.0 0.0   1   0.0 0.0 66320.0, 66320.0 -1.37
BXD20/TyJ m 113911.0 0.0   1   0.0 0.0 113911.0, 113911.0 -0.72
BXD21/TyJ m 108262.0 0.0   1   0.0 0.0 108262.0, 108262.0 -0.8
BXD22/TyJ m 95217.0 0.0   1   0.0 0.0 95217.0, 95217.0 -0.97
BXD24/TyJ m 95418.0 0.0   1   0.0 0.0 95418.0, 95418.0 -0.97
BXD24/TyJ-Cep290rd16/J m 66444.0 0.0   1   0.0 0.0 66444.0, 66444.0 -1.36
BXD28/TyJ m 156017.0 5127.0   2   3626.0 0.0329 152392.0, 159643.0 -0.15
BXD29-Tlr4lps-2J/J m 68828.0 0.0   1   0.0 0.0 68828.0, 68828.0 -1.33
BXD2/TyJ m 108198.0 0.0   1   0.0 0.0 108198.0, 108198.0 -0.8
BXD32/TyJ m 108653.0 0.0   1   0.0 0.0 108653.0, 108653.0 -0.79
BXD33/TyJ m 98383.0 0.0   1   0.0 0.0 98383.0, 98383.0 -0.93
BXD34/TyJ m 61402.0 0.0   1   0.0 0.0 61402.0, 61402.0 -1.43
BXD36/TyJ m 157180.0 0.0   1   0.0 0.0 157180.0, 157180.0 -0.13
BXD38/TyJ m 51199.0 0.0   1   0.0 0.0 51199.0, 51199.0 -1.57
BXD39/TyJ m 124489.0 0.0   1   0.0 0.0 124489.0, 124489.0 -0.58
BXD40/TyJ m 147280.0 0.0   1   0.0 0.0 147280.0, 147280.0 -0.27
BXD42/TyJ m 77535.0 0.0   1   0.0 0.0 77535.0, 77535.0 -1.21
BXD5/TyJ m 95651.0 0.0   1   0.0 0.0 95651.0, 95651.0 -0.97
BXD6/TyJ m 176065.0 0.0   1   0.0 0.0 176065.0, 176065.0 0.12
BXD8/TyJ m 79163.0 0.0   1   0.0 0.0 79163.0, 79163.0 -1.19
BXD9/TyJ m 155151.0 0.0   1   0.0 0.0 155151.0, 155151.0 -0.16
BXH10/TyJ m 159782.0 0.0   1   0.0 0.0 159782.0, 159782.0 -0.1
BXH19/TyJ m 315566.0 0.0   1   0.0 0.0 315566.0, 315566.0 2.01
BXH20/KccJ m 197894.0 0.0   1   0.0 0.0 197894.0, 197894.0 0.42
BXH22/KccJ m 157455.0 0.0   1   0.0 0.0 157455.0, 157455.0 -0.13
BXH2/TyJ m 151088.0 0.0   1   0.0 0.0 151088.0, 151088.0 -0.22
BXH4/TyJ m 204268.0 46197.0   2   32666.0 0.226 171602.0, 236934.0 0.5
BXH6/TyJ m 163245.0 0.0   1   0.0 0.0 163245.0, 163245.0 -0.05
BXH7/TyJ m 157170.0 0.0   1   0.0 0.0 157170.0, 157170.0 -0.13
BXH8/TyJ m 187278.0 0.0   1   0.0 0.0 187278.0, 187278.0 0.27
BXH9/TyJ m 153569.0 0.0   1   0.0 0.0 153569.0, 153569.0 -0.18
C3H/HeJ m 255806.0 70187.0   2   49630.0 0.274 206176.0, 305436.0 1.2
C57BL/6J m 132636.0 19952.0   5 8923.0 0.15 110662.0, 161599.0 -0.47
C57L/J m 63462.0 0.0   1   0.0 0.0 63462.0, 63462.0 -1.4
C58/J m 92998.0 0.0   1   0.0 0.0 92998.0, 92998.0 -1.0
CAST/EiJ m 109825.0 0.0   1   0.0 0.0 109825.0, 109825.0 -0.78
CBA/J m 199950.0 0.0   1   0.0 0.0 199950.0, 199950.0 0.44
CE/J m 226629.0 0.0   1   0.0 0.0 226629.0, 226629.0 0.81
CXB11/HiAJ m 204244.0 103124.0   2   72920.0 0.505 131324.0, 277164.0 0.5
CXB12/HiAJ m 120260.0 6312.0   2   4463.0 0.0525 115797.0, 124724.0 -0.63
CXB13/HiAJ m 170207.0 23279.0   3 13440.0 0.137 149591.0, 195452.0 0.04
CXB1/ByJ m 236248.0 23594.0   3 13622.0 0.0999 213932.0, 260940.0 0.94
CXB2/ByJ m 159913.0 72860.0   3 42066.0 0.456 92653.0, 237312.0 -0.1
CXB3/ByJ m 207487.0 65229.0   2   46124.0 0.314 161362.0, 253611.0 0.55
CXB4/ByJ m 261057.0 47323.0   2   33463.0 0.181 227594.0, 294519.0 1.27
CXB6/ByJ m 223144.0 30689.0   3 17718.0 0.138 189858.0, 250314.0 0.76
CXB7/ByJ m 270337.0 31786.0   2   22476.0 0.118 247861.0, 292813.0 1.4
CXB8/HiAJ m 203708.0 46141.0   3 26639.0 0.227 160301.0, 252167.0 0.5
CXB9/HiAJ m 191495.0 37337.0   3 21557.0 0.195 149787.0, 221804.0 0.33
DBA/2J m 102423.0 6699.0   4 3349.0 0.0654 98540.0, 112440.0 -0.88
FVB/NJ m 348447.0 0.0   1   0.0 0.0 348447.0, 348447.0 2.45
I/LnJ m 168321.0 0.0   1   0.0 0.0 168321.0, 168321.0 0.02
KK/HlJ m 199543.0 0.0   1   0.0 0.0 199543.0, 199543.0 0.44
LG/J m 234617.0 0.0   1   0.0 0.0 234617.0, 234617.0 0.91
LP/J m 146892.0 0.0   1   0.0 0.0 146892.0, 146892.0 -0.27
MA/MyJ m 151554.0 0.0   1   0.0 0.0 151554.0, 151554.0 -0.21
NOD/ShiLtJ m 206833.0 0.0   1   0.0 0.0 206833.0, 206833.0 0.54
NON/ShiLtJ m 117238.0 0.0   1   0.0 0.0 117238.0, 117238.0 -0.68
NZW/LacJ m 187453.0 0.0   1   0.0 0.0 187453.0, 187453.0 0.28
PL/J m 217353.0 0.0   1   0.0 0.0 217353.0, 217353.0 0.68
RIIIS/J m 168554.0 0.0   1   0.0 0.0 168554.0, 168554.0 0.02
SEA/GnJ m 187799.0 0.0   1   0.0 0.0 187799.0, 187799.0 0.28
SJL/J m 109735.0 0.0   1   0.0 0.0 109735.0, 109735.0 -0.78
SM/J m 63671.0 0.0   1   0.0 0.0 63671.0, 63671.0 -1.4
SWR/J m 171819.0 0.0   1   0.0 0.0 171819.0, 171819.0 0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 220343.95 31861.9464 285095.2156 155592.6844
AXB19b/PgnJ m 124713.45 31861.9464 189464.7156 59962.1844
AXB24/PgnJ m 217902.35 31861.9464 282653.6156 153151.0844
BALB/cJ m 264541.2333 26015.1703 317410.4203 211672.0463
BXA16/PgnJ m 159655.9 31861.9464 224407.1656 94904.6344
BXD19/TyJ m 164516.2 31861.9464 229267.4656 99764.9344
BXD28/TyJ m 156017.25 31861.9464 220768.5156 91265.9844
BXH4/TyJ m 204268.5 31861.9464 269019.7656 139517.2344
C3H/HeJ m 255805.65 31861.9464 320556.9156 191054.3844
C57BL/6J m 132635.86 20151.2643 173588.1562 91683.5638
CXB11/HiAJ m 204244.4 31861.9464 268995.6656 139493.1344
CXB12/HiAJ m 120260.4 31861.9464 185011.6656 55509.1344
CXB13/HiAJ m 170206.8667 26015.1703 223076.0537 117337.6797
CXB1/ByJ m 236247.7333 26015.1703 289116.9203 183378.5463
CXB2/ByJ m 159912.7333 26015.1703 212781.9203 107043.5463
CXB3/ByJ m 207486.55 31861.9464 272237.8156 142735.2844
CXB4/ByJ m 261056.75 31861.9464 325808.0156 196305.4844
CXB6/ByJ m 223144.4 26015.1703 276013.587 170275.213
CXB7/ByJ m 270337.15 31861.9464 335088.4156 205585.8844
CXB8/HiAJ m 203707.8 26015.1703 256576.987 150838.613
CXB9/HiAJ m 191494.8 26015.1703 244363.987 138625.613
DBA/2J m 102422.85 22529.7984 148208.909 56636.791




  GWAS USING LINEAR MIXED MODELS