Project measure / variable:   HMDPpheno6   MeLAA

ID, description, units MPD:50137   MeLAA   liver 1-methylimidazoleacetate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   91 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 1-methylimidazoleacetate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested91 strains
Mean of the strain means69442   None
Median of the strain means54398   None
SD of the strain means± 56982
Coefficient of variation (CV)0.821
Min–max range of strain means24172   –   368551   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 32329040230.8838 1539478106.2326 2.4351 0.012
Residuals 31 19598038141.1475 632194778.7467


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 27903.0 0.0   1   0.0 0.0 27903.0, 27903.0 -0.73
A/J m 94057.0 1411.0   2   998.0 0.015 93060.0, 95055.0 0.43
AXB10/PgnJ m 44551.0 0.0   1   0.0 0.0 44551.0, 44551.0 -0.44
AXB12/PgnJ m 31335.0 0.0   1   0.0 0.0 31335.0, 31335.0 -0.67
AXB19a/PgnJ m 129810.0 0.0   1   0.0 0.0 129810.0, 129810.0 1.06
AXB19b/PgnJ m 55943.0 17968.0   2   12705.0 0.321 43237.0, 68648.0 -0.24
AXB19/PgnJ m 85570.0 0.0   1   0.0 0.0 85570.0, 85570.0 0.28
AXB1/PgnJ m 86616.0 0.0   1   0.0 0.0 86616.0, 86616.0 0.3
AXB23/PgnJ m 36267.0 0.0   1   0.0 0.0 36267.0, 36267.0 -0.58
AXB24/PgnJ m 55394.0 3828.0   2   2707.0 0.0691 52688.0, 58102.0 -0.25
AXB4/PgnJ m 30819.0 0.0   1   0.0 0.0 30819.0, 30819.0 -0.68
AXB5/PgnJ m 53319.0 0.0   1   0.0 0.0 53319.0, 53319.0 -0.28
AXB8/PgnJ m 27187.0 0.0   1   0.0 0.0 27187.0, 27187.0 -0.74
BALB/cJ m 49221.0 21951.0   3 12673.0 0.446 35553.0, 74540.0 -0.35
BTBR T+ Itpr3tf/J m 63245.0 0.0   1   0.0 0.0 63245.0, 63245.0 -0.11
BXA11/PgnJ m 51554.0 0.0   1   0.0 0.0 51554.0, 51554.0 -0.31
BXA12/PgnJ m 42065.0 0.0   1   0.0 0.0 42065.0, 42065.0 -0.48
BXA13/PgnJ m 55817.0 0.0   1   0.0 0.0 55817.0, 55817.0 -0.24
BXA16/PgnJ m 44052.0 13869.0   2   9807.0 0.315 34246.0, 53859.0 -0.45
BXA1/PgnJ m 39151.0 0.0   1   0.0 0.0 39151.0, 39151.0 -0.53
BXA25/PgnJ m 61429.0 0.0   1   0.0 0.0 61429.0, 61429.0 -0.14
BXA26/PgnJ m 47225.0 0.0   1   0.0 0.0 47225.0, 47225.0 -0.39
BXA2/PgnJ m 55177.0 0.0   1   0.0 0.0 55177.0, 55177.0 -0.25
BXA4/PgnJ m 40868.0 0.0   1   0.0 0.0 40868.0, 40868.0 -0.5
BXA7/PgnJ m 52716.0 0.0   1   0.0 0.0 52716.0, 52716.0 -0.29
BXA8/PgnJ m 61809.0 0.0   1   0.0 0.0 61809.0, 61809.0 -0.13
BXD12/TyJ m 331268.0 0.0   1   0.0 0.0 331268.0, 331268.0 4.59
BXD13/TyJ m 77339.0 0.0   1   0.0 0.0 77339.0, 77339.0 0.14
BXD14/TyJ m 43014.0 0.0   1   0.0 0.0 43014.0, 43014.0 -0.46
BXD15/TyJ m 47726.0 0.0   1   0.0 0.0 47726.0, 47726.0 -0.38
BXD18/TyJ m 30768.0 0.0   1   0.0 0.0 30768.0, 30768.0 -0.68
BXD19/TyJ m 46808.0 3557.0   2   2515.0 0.076 44293.0, 49323.0 -0.4
BXD1/TyJ m 24172.0 0.0   1   0.0 0.0 24172.0, 24172.0 -0.79
BXD20/TyJ m 67198.0 0.0   1   0.0 0.0 67198.0, 67198.0 -0.04
BXD21/TyJ m 33553.0 0.0   1   0.0 0.0 33553.0, 33553.0 -0.63
BXD22/TyJ m 46125.0 0.0   1   0.0 0.0 46125.0, 46125.0 -0.41
BXD24/TyJ m 52015.0 0.0   1   0.0 0.0 52015.0, 52015.0 -0.31
BXD24/TyJ-Cep290rd16/J m 165476.0 0.0   1   0.0 0.0 165476.0, 165476.0 1.69
BXD28/TyJ m 55925.0 18537.0   2   13108.0 0.331 42817.0, 69033.0 -0.24
BXD29-Tlr4lps-2J/J m 111126.0 0.0   1   0.0 0.0 111126.0, 111126.0 0.73
BXD2/TyJ m 77447.0 0.0   1   0.0 0.0 77447.0, 77447.0 0.14
BXD32/TyJ m 28463.0 0.0   1   0.0 0.0 28463.0, 28463.0 -0.72
BXD33/TyJ m 26351.0 0.0   1   0.0 0.0 26351.0, 26351.0 -0.76
BXD34/TyJ m 53859.0 0.0   1   0.0 0.0 53859.0, 53859.0 -0.27
BXD36/TyJ m 47252.0 0.0   1   0.0 0.0 47252.0, 47252.0 -0.39
BXD38/TyJ m 43271.0 0.0   1   0.0 0.0 43271.0, 43271.0 -0.46
BXD39/TyJ m 59295.0 0.0   1   0.0 0.0 59295.0, 59295.0 -0.18
BXD40/TyJ m 120040.0 0.0   1   0.0 0.0 120040.0, 120040.0 0.89
BXD42/TyJ m 270389.0 0.0   1   0.0 0.0 270389.0, 270389.0 3.53
BXD5/TyJ m 54398.0 0.0   1   0.0 0.0 54398.0, 54398.0 -0.26
BXD6/TyJ m 36907.0 0.0   1   0.0 0.0 36907.0, 36907.0 -0.57
BXD8/TyJ m 44549.0 0.0   1   0.0 0.0 44549.0, 44549.0 -0.44
BXD9/TyJ m 55286.0 0.0   1   0.0 0.0 55286.0, 55286.0 -0.25
BXH10/TyJ m 368551.0 0.0   1   0.0 0.0 368551.0, 368551.0 5.25
BXH19/TyJ m 72886.0 0.0   1   0.0 0.0 72886.0, 72886.0 0.06
BXH20/KccJ m 68961.0 0.0   1   0.0 0.0 68961.0, 68961.0 -0.01
BXH22/KccJ m 42644.0 0.0   1   0.0 0.0 42644.0, 42644.0 -0.47
BXH2/TyJ m 57358.0 0.0   1   0.0 0.0 57358.0, 57358.0 -0.21
BXH4/TyJ m 149844.0 95510.0   2   67536.0 0.637 82308.0, 217380.0 1.41
BXH6/TyJ m 180333.0 0.0   1   0.0 0.0 180333.0, 180333.0 1.95
BXH7/TyJ m 56264.0 0.0   1   0.0 0.0 56264.0, 56264.0 -0.23
BXH8/TyJ m 62156.0 0.0   1   0.0 0.0 62156.0, 62156.0 -0.13
BXH9/TyJ m 42478.0 0.0   1   0.0 0.0 42478.0, 42478.0 -0.47
C3H/HeJ m 78838.0 1405.0   2   994.0 0.0178 77844.0, 79831.0 0.16
C57BL/6J m 45754.0 9024.0   3 5210.0 0.197 40140.0, 56163.0 -0.42
C57L/J m 73221.0 0.0   1   0.0 0.0 73221.0, 73221.0 0.07
C58/J m 96208.0 0.0   1   0.0 0.0 96208.0, 96208.0 0.47
CAST/EiJ m 35904.0 0.0   1   0.0 0.0 35904.0, 35904.0 -0.59
CBA/J m 34476.0 0.0   1   0.0 0.0 34476.0, 34476.0 -0.61
CE/J m 41218.0 0.0   1   0.0 0.0 41218.0, 41218.0 -0.5
CXB11/HiAJ m 118889.0 63919.0   2   45198.0 0.538 73692.0, 164087.0 0.87
CXB12/HiAJ m 78427.0 17116.0   2   12103.0 0.218 66324.0, 90530.0 0.16
CXB13/HiAJ m 60660.0 33938.0   3 19594.0 0.559 28571.0, 96186.0 -0.15
CXB1/ByJ m 66375.0 14434.0   3 8334.0 0.217 49813.0, 76272.0 -0.05
CXB2/ByJ m 48402.0 9390.0   3 5421.0 0.194 40576.0, 58815.0 -0.37
CXB3/ByJ m 69202.0 7832.0   2   5538.0 0.113 63663.0, 74740.0 0.0
CXB4/ByJ m 50396.0 2127.0   2   1504.0 0.0422 48892.0, 51900.0 -0.33
CXB6/ByJ m 54618.0 6253.0   3 3610.0 0.114 47451.0, 58958.0 -0.26
CXB7/ByJ m 57402.0 11305.0   2   7994.0 0.197 49408.0, 65396.0 -0.21
CXB8/HiAJ m 44756.0 13171.0   3 7604.0 0.294 30335.0, 56150.0 -0.43
CXB9/HiAJ m 44613.0 20725.0   2   14655.0 0.465 29959.0, 59268.0 -0.44
DBA/2J m 39909.0 6722.0   4 3361.0 0.168 30939.0, 47154.0 -0.52
FVB/NJ m 86352.0 0.0   1   0.0 0.0 86352.0, 86352.0 0.3
I/LnJ m 174610.0 0.0   1   0.0 0.0 174610.0, 174610.0 1.85
KK/HlJ m 71275.0 0.0   1   0.0 0.0 71275.0, 71275.0 0.03
LG/J m 64394.0 0.0   1   0.0 0.0 64394.0, 64394.0 -0.09
NZW/LacJ m 36435.0 0.0   1   0.0 0.0 36435.0, 36435.0 -0.58
PL/J m 56384.0 0.0   1   0.0 0.0 56384.0, 56384.0 -0.23
SEA/GnJ m 27622.0 0.0   1   0.0 0.0 27622.0, 27622.0 -0.73
SM/J m 45908.0 0.0   1   0.0 0.0 45908.0, 45908.0 -0.41
SWR/J m 42410.0 0.0   1   0.0 0.0 42410.0, 42410.0 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 94057.25 17779.1279 130318.0204 57796.4796
AXB19b/PgnJ m 55942.85 17779.1279 92203.6204 19682.0796
AXB24/PgnJ m 55394.5 17779.1279 91655.2704 19133.7296
BALB/cJ m 49220.5333 14516.5972 78827.3284 19613.7382
BXA16/PgnJ m 44052.05 17779.1279 80312.8204 7791.2796
BXD19/TyJ m 46808.25 17779.1279 83069.0204 10547.4796
BXD28/TyJ m 55924.65 17779.1279 92185.4204 19663.8796
BXH4/TyJ m 149843.6 17779.1279 186104.3704 113582.8296
C3H/HeJ m 78837.55 17779.1279 115098.3204 42576.7796
C57BL/6J m 45754.1333 14516.5972 75360.9284 16147.3382
CXB11/HiAJ m 118889.15 17779.1279 155149.9204 82628.3796
CXB12/HiAJ m 78427.2 17779.1279 114687.9704 42166.4296
CXB13/HiAJ m 60659.7667 14516.5972 90266.5618 31052.9716
CXB1/ByJ m 66375.2667 14516.5972 95982.0618 36768.4716
CXB2/ByJ m 48402.3667 14516.5972 78009.1618 18795.5716
CXB3/ByJ m 69201.7 17779.1279 105462.4704 32940.9296
CXB4/ByJ m 50396.2 17779.1279 86656.9704 14135.4296
CXB6/ByJ m 54618.2667 14516.5972 84225.0618 25011.4716
CXB7/ByJ m 57402.0 17779.1279 93662.7704 21141.2296
CXB8/HiAJ m 44756.0 14516.5972 74362.7951 15149.2049
CXB9/HiAJ m 44613.15 17779.1279 80873.9204 8352.3796
DBA/2J m 39909.325 12571.7419 65549.5617 14269.0883




  GWAS USING LINEAR MIXED MODELS