Project measure / variable:   HMDPpheno6   HP_lactate

ID, description, units MPD:50147   HP_lactate   liver 3-(4-hydroxyphenyl)lactate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 3-(4-hydroxyphenyl)lactate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means25902   None
Median of the strain means24737   None
SD of the strain means± 7148
Coefficient of variation (CV)0.276
Min–max range of strain means13918   –   55431   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 1107008162.676 52714674.4131 1.4717 0.1542
Residuals 34 1217818609.0038 35818194.3825


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 28551.0 0.0   1   0.0 0.0 28551.0, 28551.0 0.37
A/J m 30728.0 5152.0   2   3643.0 0.168 27085.0, 34371.0 0.68
AKR/J m 16700.0 0.0   1   0.0 0.0 16700.0, 16700.0 -1.29
AXB10/PgnJ m 33646.0 0.0   1   0.0 0.0 33646.0, 33646.0 1.08
AXB12/PgnJ m 16610.0 0.0   1   0.0 0.0 16610.0, 16610.0 -1.3
AXB13/PgnJ m 28916.0 0.0   1   0.0 0.0 28916.0, 28916.0 0.42
AXB15/PgnJ m 32725.0 0.0   1   0.0 0.0 32725.0, 32725.0 0.95
AXB19a/PgnJ m 55431.0 0.0   1   0.0 0.0 55431.0, 55431.0 4.13
AXB19b/PgnJ m 34304.0 4172.0   2   2950.0 0.122 31354.0, 37255.0 1.18
AXB19/PgnJ m 35692.0 0.0   1   0.0 0.0 35692.0, 35692.0 1.37
AXB1/PgnJ m 31015.0 0.0   1   0.0 0.0 31015.0, 31015.0 0.72
AXB23/PgnJ m 22173.0 0.0   1   0.0 0.0 22173.0, 22173.0 -0.52
AXB24/PgnJ m 21732.0 1240.0   2   877.0 0.057 20856.0, 22609.0 -0.58
AXB2/PgnJ m 14872.0 0.0   1   0.0 0.0 14872.0, 14872.0 -1.54
AXB4/PgnJ m 25043.0 0.0   1   0.0 0.0 25043.0, 25043.0 -0.12
AXB5/PgnJ m 19035.0 0.0   1   0.0 0.0 19035.0, 19035.0 -0.96
AXB6/PgnJ m 31154.0 0.0   1   0.0 0.0 31154.0, 31154.0 0.73
AXB8/PgnJ m 37728.0 0.0   1   0.0 0.0 37728.0, 37728.0 1.65
BALB/cJ m 22411.0 1901.0   3 1097.0 0.0848 20611.0, 24399.0 -0.49
BTBR T+ Itpr3tf/J m 17790.0 0.0   1   0.0 0.0 17790.0, 17790.0 -1.13
BUB/BnJ m 15850.0 0.0   1   0.0 0.0 15850.0, 15850.0 -1.41
BXA11/PgnJ m 15395.0 0.0   1   0.0 0.0 15395.0, 15395.0 -1.47
BXA12/PgnJ m 24749.0 0.0   1   0.0 0.0 24749.0, 24749.0 -0.16
BXA13/PgnJ m 32161.0 0.0   1   0.0 0.0 32161.0, 32161.0 0.88
BXA14/PgnJ m 41924.0 0.0   1   0.0 0.0 41924.0, 41924.0 2.24
BXA16/PgnJ m 31277.0 11749.0   2   8308.0 0.376 22969.0, 39584.0 0.75
BXA1/PgnJ m 24725.0 0.0   1   0.0 0.0 24725.0, 24725.0 -0.16
BXA24/PgnJ m 36052.0 0.0   1   0.0 0.0 36052.0, 36052.0 1.42
BXA25/PgnJ m 27132.0 0.0   1   0.0 0.0 27132.0, 27132.0 0.17
BXA26/PgnJ m 32571.0 0.0   1   0.0 0.0 32571.0, 32571.0 0.93
BXA2/PgnJ m 13918.0 0.0   1   0.0 0.0 13918.0, 13918.0 -1.68
BXA4/PgnJ m 41352.0 0.0   1   0.0 0.0 41352.0, 41352.0 2.16
BXA7/PgnJ m 21814.0 0.0   1   0.0 0.0 21814.0, 21814.0 -0.57
BXA8/PgnJ m 20157.0 0.0   1   0.0 0.0 20157.0, 20157.0 -0.8
BXD11/TyJ m 20767.0 0.0   1   0.0 0.0 20767.0, 20767.0 -0.72
BXD12/TyJ m 23544.0 0.0   1   0.0 0.0 23544.0, 23544.0 -0.33
BXD13/TyJ m 16798.0 0.0   1   0.0 0.0 16798.0, 16798.0 -1.27
BXD14/TyJ m 39275.0 0.0   1   0.0 0.0 39275.0, 39275.0 1.87
BXD15/TyJ m 17430.0 0.0   1   0.0 0.0 17430.0, 17430.0 -1.19
BXD18/TyJ m 15228.0 0.0   1   0.0 0.0 15228.0, 15228.0 -1.49
BXD19/TyJ m 30204.0 9542.0   2   6747.0 0.316 23457.0, 36951.0 0.6
BXD1/TyJ m 29581.0 0.0   1   0.0 0.0 29581.0, 29581.0 0.51
BXD20/TyJ m 22074.0 0.0   1   0.0 0.0 22074.0, 22074.0 -0.54
BXD21/TyJ m 26293.0 0.0   1   0.0 0.0 26293.0, 26293.0 0.05
BXD22/TyJ m 25457.0 0.0   1   0.0 0.0 25457.0, 25457.0 -0.06
BXD24/TyJ m 21360.0 0.0   1   0.0 0.0 21360.0, 21360.0 -0.64
BXD24/TyJ-Cep290rd16/J m 28324.0 0.0   1   0.0 0.0 28324.0, 28324.0 0.34
BXD28/TyJ m 20326.0 2428.0   2   1717.0 0.119 18609.0, 22043.0 -0.78
BXD29-Tlr4lps-2J/J m 26360.0 0.0   1   0.0 0.0 26360.0, 26360.0 0.06
BXD2/TyJ m 17400.0 0.0   1   0.0 0.0 17400.0, 17400.0 -1.19
BXD32/TyJ m 24914.0 0.0   1   0.0 0.0 24914.0, 24914.0 -0.14
BXD33/TyJ m 39752.0 0.0   1   0.0 0.0 39752.0, 39752.0 1.94
BXD34/TyJ m 18325.0 0.0   1   0.0 0.0 18325.0, 18325.0 -1.06
BXD36/TyJ m 25223.0 0.0   1   0.0 0.0 25223.0, 25223.0 -0.1
BXD38/TyJ m 21157.0 0.0   1   0.0 0.0 21157.0, 21157.0 -0.66
BXD39/TyJ m 24638.0 0.0   1   0.0 0.0 24638.0, 24638.0 -0.18
BXD40/TyJ m 20694.0 0.0   1   0.0 0.0 20694.0, 20694.0 -0.73
BXD42/TyJ m 31044.0 0.0   1   0.0 0.0 31044.0, 31044.0 0.72
BXD5/TyJ m 31586.0 0.0   1   0.0 0.0 31586.0, 31586.0 0.8
BXD6/TyJ m 20458.0 0.0   1   0.0 0.0 20458.0, 20458.0 -0.76
BXD8/TyJ m 34774.0 0.0   1   0.0 0.0 34774.0, 34774.0 1.24
BXD9/TyJ m 23658.0 0.0   1   0.0 0.0 23658.0, 23658.0 -0.31
BXH10/TyJ m 30352.0 0.0   1   0.0 0.0 30352.0, 30352.0 0.62
BXH19/TyJ m 25673.0 0.0   1   0.0 0.0 25673.0, 25673.0 -0.03
BXH20/KccJ m 26283.0 0.0   1   0.0 0.0 26283.0, 26283.0 0.05
BXH22/KccJ m 18472.0 0.0   1   0.0 0.0 18472.0, 18472.0 -1.04
BXH2/TyJ m 24667.0 0.0   1   0.0 0.0 24667.0, 24667.0 -0.17
BXH4/TyJ m 24295.0 5907.0   2   4177.0 0.243 20118.0, 28472.0 -0.22
BXH6/TyJ m 27811.0 0.0   1   0.0 0.0 27811.0, 27811.0 0.27
BXH7/TyJ m 18680.0 0.0   1   0.0 0.0 18680.0, 18680.0 -1.01
BXH8/TyJ m 24363.0 0.0   1   0.0 0.0 24363.0, 24363.0 -0.22
BXH9/TyJ m 21138.0 0.0   1   0.0 0.0 21138.0, 21138.0 -0.67
C3H/HeJ m 31120.0 5565.0   2   3935.0 0.179 27184.0, 35055.0 0.73
C57BL/6J m 23203.0 4446.0   5 1988.0 0.192 18850.0, 27894.0 -0.38
C57L/J m 22077.0 0.0   1   0.0 0.0 22077.0, 22077.0 -0.54
C58/J m 32004.0 0.0   1   0.0 0.0 32004.0, 32004.0 0.85
CAST/EiJ m 23016.0 0.0   1   0.0 0.0 23016.0, 23016.0 -0.4
CBA/J m 18058.0 0.0   1   0.0 0.0 18058.0, 18058.0 -1.1
CE/J m 37555.0 0.0   1   0.0 0.0 37555.0, 37555.0 1.63
CXB11/HiAJ m 26265.0 12262.0   2   8671.0 0.467 17594.0, 34936.0 0.05
CXB12/HiAJ m 29376.0 5410.0   2   3825.0 0.184 25551.0, 33202.0 0.49
CXB13/HiAJ m 32528.0 6553.0   3 3783.0 0.201 25171.0, 37742.0 0.93
CXB1/ByJ m 29107.0 11210.0   3 6472.0 0.385 20930.0, 41886.0 0.45
CXB2/ByJ m 23178.0 4408.0   3 2545.0 0.19 18364.0, 27016.0 -0.38
CXB3/ByJ m 29282.0 8969.0   2   6342.0 0.306 22940.0, 35624.0 0.47
CXB4/ByJ m 28260.0 1593.0   2   1126.0 0.0564 27134.0, 29386.0 0.33
CXB6/ByJ m 21097.0 357.0   3 206.0 0.0169 20714.0, 21421.0 -0.67
CXB7/ByJ m 31271.0 2334.0   2   1650.0 0.0746 29621.0, 32922.0 0.75
CXB8/HiAJ m 35505.0 7019.0   3 4052.0 0.198 28746.0, 42758.0 1.34
CXB9/HiAJ m 26462.0 4414.0   3 2548.0 0.167 23861.0, 31558.0 0.08
DBA/2J m 23334.0 1050.0   4 525.0 0.045 21996.0, 24564.0 -0.36
FVB/NJ m 16458.0 0.0   1   0.0 0.0 16458.0, 16458.0 -1.32
I/LnJ m 22563.0 0.0   1   0.0 0.0 22563.0, 22563.0 -0.47
KK/HlJ m 24317.0 0.0   1   0.0 0.0 24317.0, 24317.0 -0.22
LG/J m 24083.0 0.0   1   0.0 0.0 24083.0, 24083.0 -0.25
LP/J m 22891.0 0.0   1   0.0 0.0 22891.0, 22891.0 -0.42
MA/MyJ m 15508.0 0.0   1   0.0 0.0 15508.0, 15508.0 -1.45
NOD/ShiLtJ m 19602.0 0.0   1   0.0 0.0 19602.0, 19602.0 -0.88
NON/ShiLtJ m 35701.0 0.0   1   0.0 0.0 35701.0, 35701.0 1.37
NZW/LacJ m 24594.0 0.0   1   0.0 0.0 24594.0, 24594.0 -0.18
PL/J m 24868.0 0.0   1   0.0 0.0 24868.0, 24868.0 -0.14
RIIIS/J m 17876.0 0.0   1   0.0 0.0 17876.0, 17876.0 -1.12
SEA/GnJ m 22478.0 0.0   1   0.0 0.0 22478.0, 22478.0 -0.48
SJL/J m 16018.0 0.0   1   0.0 0.0 16018.0, 16018.0 -1.38
SM/J m 32231.0 0.0   1   0.0 0.0 32231.0, 32231.0 0.89
SWR/J m 30058.0 0.0   1   0.0 0.0 30058.0, 30058.0 0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 30728.0 4231.9141 39328.2843 22127.7157
AXB19b/PgnJ m 34304.5 4231.9141 42904.7843 25704.2157
AXB24/PgnJ m 21732.3 4231.9141 30332.5843 13132.0157
BALB/cJ m 22411.1667 3455.3434 29433.2694 15389.064
BXA16/PgnJ m 31276.7 4231.9141 39876.9843 22676.4157
BXD19/TyJ m 30204.05 4231.9141 38804.3343 21603.7657
BXD28/TyJ m 20326.05 4231.9141 28926.3343 11725.7657
BXH4/TyJ m 24294.75 4231.9141 32895.0343 15694.4657
C3H/HeJ m 31119.55 4231.9141 39719.8343 22519.2657
C57BL/6J m 23202.82 2676.4975 28642.1174 17763.5226
CXB11/HiAJ m 26265.25 4231.9141 34865.5343 17664.9657
CXB12/HiAJ m 29376.15 4231.9141 37976.4343 20775.8657
CXB13/HiAJ m 32527.7 3455.3434 39549.8027 25505.5973
CXB1/ByJ m 29107.2667 3455.3434 36129.3694 22085.164
CXB2/ByJ m 23178.4 3455.3434 30200.5027 16156.2973
CXB3/ByJ m 29281.5 4231.9141 37881.7843 20681.2157
CXB4/ByJ m 28260.1 4231.9141 36860.3843 19659.8157
CXB6/ByJ m 21096.9333 3455.3434 28119.036 14074.8306
CXB7/ByJ m 31271.45 4231.9141 39871.7343 22671.1657
CXB8/HiAJ m 35505.4333 3455.3434 42527.536 28483.3306
CXB9/HiAJ m 26462.3667 3455.3434 33484.4694 19440.264
DBA/2J m 23334.425 2992.4152 29415.7443 17253.1057




  GWAS USING LINEAR MIXED MODELS