Project measure / variable:   HMDPpheno6   acetyl_Glu

ID, description, units MPD:50118   acetyl_Glu   liver N-acetylglutamate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver N-acetylglutamate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means190203   None
Median of the strain means139470   None
SD of the strain means± 198459
Coefficient of variation (CV)1.04
Min–max range of strain means52781   –   1866676   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 325272086491.129 15489146975.768 4.2056 0.0001
Residuals 34 125222489544.391 3683014398.3644


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 93363.0 0.0   1   0.0 0.0 93363.0, 93363.0 -0.49
A/J m 124695.0 30123.0   2   21300.0 0.242 103395.0, 145995.0 -0.33
AKR/J m 67284.0 0.0   1   0.0 0.0 67284.0, 67284.0 -0.62
AXB10/PgnJ m 213575.0 0.0   1   0.0 0.0 213575.0, 213575.0 0.12
AXB12/PgnJ m 381432.0 0.0   1   0.0 0.0 381432.0, 381432.0 0.96
AXB13/PgnJ m 77609.0 0.0   1   0.0 0.0 77609.0, 77609.0 -0.57
AXB15/PgnJ m 133316.0 0.0   1   0.0 0.0 133316.0, 133316.0 -0.29
AXB19a/PgnJ m 138253.0 0.0   1   0.0 0.0 138253.0, 138253.0 -0.26
AXB19b/PgnJ m 92595.0 1689.0   2   1194.0 0.0182 91400.0, 93789.0 -0.49
AXB19/PgnJ m 142398.0 0.0   1   0.0 0.0 142398.0, 142398.0 -0.24
AXB1/PgnJ m 119572.0 0.0   1   0.0 0.0 119572.0, 119572.0 -0.36
AXB23/PgnJ m 92832.0 0.0   1   0.0 0.0 92832.0, 92832.0 -0.49
AXB24/PgnJ m 247863.0 166925.0   2   118034.0 0.673 129829.0, 365896.0 0.29
AXB2/PgnJ m 151910.0 0.0   1   0.0 0.0 151910.0, 151910.0 -0.19
AXB4/PgnJ m 74647.0 0.0   1   0.0 0.0 74647.0, 74647.0 -0.58
AXB5/PgnJ m 238561.0 0.0   1   0.0 0.0 238561.0, 238561.0 0.24
AXB6/PgnJ m 297431.0 0.0   1   0.0 0.0 297431.0, 297431.0 0.54
AXB8/PgnJ m 288352.0 0.0   1   0.0 0.0 288352.0, 288352.0 0.49
BALB/cJ m 193715.0 58214.0   3 33610.0 0.301 148490.0, 259396.0 0.02
BTBR T+ Itpr3tf/J m 64770.0 0.0   1   0.0 0.0 64770.0, 64770.0 -0.63
BUB/BnJ m 153738.0 0.0   1   0.0 0.0 153738.0, 153738.0 -0.18
BXA11/PgnJ m 129936.0 0.0   1   0.0 0.0 129936.0, 129936.0 -0.3
BXA12/PgnJ m 159250.0 0.0   1   0.0 0.0 159250.0, 159250.0 -0.16
BXA13/PgnJ m 105089.0 0.0   1   0.0 0.0 105089.0, 105089.0 -0.43
BXA14/PgnJ m 343167.0 0.0   1   0.0 0.0 343167.0, 343167.0 0.77
BXA16/PgnJ m 222131.0 234348.0   2   165709.0 1.06 56422.0, 387840.0 0.16
BXA1/PgnJ m 138146.0 0.0   1   0.0 0.0 138146.0, 138146.0 -0.26
BXA24/PgnJ m 190664.0 0.0   1   0.0 0.0 190664.0, 190664.0 0.0
BXA25/PgnJ m 95178.0 0.0   1   0.0 0.0 95178.0, 95178.0 -0.48
BXA26/PgnJ m 265769.0 0.0   1   0.0 0.0 265769.0, 265769.0 0.38
BXA2/PgnJ m 87162.0 0.0   1   0.0 0.0 87162.0, 87162.0 -0.52
BXA4/PgnJ m 231285.0 0.0   1   0.0 0.0 231285.0, 231285.0 0.21
BXA7/PgnJ m 85980.0 0.0   1   0.0 0.0 85980.0, 85980.0 -0.53
BXA8/PgnJ m 219328.0 0.0   1   0.0 0.0 219328.0, 219328.0 0.15
BXD11/TyJ m 197223.0 0.0   1   0.0 0.0 197223.0, 197223.0 0.04
BXD12/TyJ m 166775.0 0.0   1   0.0 0.0 166775.0, 166775.0 -0.12
BXD13/TyJ m 175751.0 0.0   1   0.0 0.0 175751.0, 175751.0 -0.07
BXD14/TyJ m 305146.0 0.0   1   0.0 0.0 305146.0, 305146.0 0.58
BXD15/TyJ m 174281.0 0.0   1   0.0 0.0 174281.0, 174281.0 -0.08
BXD18/TyJ m 84665.0 0.0   1   0.0 0.0 84665.0, 84665.0 -0.53
BXD19/TyJ m 192443.0 143827.0   2   101701.0 0.747 90742.0, 294144.0 0.01
BXD1/TyJ m 81072.0 0.0   1   0.0 0.0 81072.0, 81072.0 -0.55
BXD20/TyJ m 102568.0 0.0   1   0.0 0.0 102568.0, 102568.0 -0.44
BXD21/TyJ m 200489.0 0.0   1   0.0 0.0 200489.0, 200489.0 0.05
BXD22/TyJ m 112012.0 0.0   1   0.0 0.0 112012.0, 112012.0 -0.39
BXD24/TyJ m 201109.0 0.0   1   0.0 0.0 201109.0, 201109.0 0.05
BXD24/TyJ-Cep290rd16/J m 426465.0 0.0   1   0.0 0.0 426465.0, 426465.0 1.19
BXD28/TyJ m 156414.0 29665.0   2   20976.0 0.19 135438.0, 177390.0 -0.17
BXD29-Tlr4lps-2J/J m 353089.0 0.0   1   0.0 0.0 353089.0, 353089.0 0.82
BXD2/TyJ m 308898.0 0.0   1   0.0 0.0 308898.0, 308898.0 0.6
BXD32/TyJ m 502763.0 0.0   1   0.0 0.0 502763.0, 502763.0 1.57
BXD33/TyJ m 679662.0 0.0   1   0.0 0.0 679662.0, 679662.0 2.47
BXD34/TyJ m 184152.0 0.0   1   0.0 0.0 184152.0, 184152.0 -0.03
BXD36/TyJ m 609620.0 0.0   1   0.0 0.0 609620.0, 609620.0 2.11
BXD38/TyJ m 321794.0 0.0   1   0.0 0.0 321794.0, 321794.0 0.66
BXD39/TyJ m 116987.0 0.0   1   0.0 0.0 116987.0, 116987.0 -0.37
BXD40/TyJ m 139826.0 0.0   1   0.0 0.0 139826.0, 139826.0 -0.25
BXD42/TyJ m 268167.0 0.0   1   0.0 0.0 268167.0, 268167.0 0.39
BXD5/TyJ m 181157.0 0.0   1   0.0 0.0 181157.0, 181157.0 -0.05
BXD6/TyJ m 139113.0 0.0   1   0.0 0.0 139113.0, 139113.0 -0.26
BXD8/TyJ m 219658.0 0.0   1   0.0 0.0 219658.0, 219658.0 0.15
BXD9/TyJ m 152795.0 0.0   1   0.0 0.0 152795.0, 152795.0 -0.19
BXH10/TyJ m 148921.0 0.0   1   0.0 0.0 148921.0, 148921.0 -0.21
BXH19/TyJ m 58012.0 0.0   1   0.0 0.0 58012.0, 58012.0 -0.67
BXH20/KccJ m 106182.0 0.0   1   0.0 0.0 106182.0, 106182.0 -0.42
BXH22/KccJ m 113706.0 0.0   1   0.0 0.0 113706.0, 113706.0 -0.39
BXH2/TyJ m 83152.0 0.0   1   0.0 0.0 83152.0, 83152.0 -0.54
BXH4/TyJ m 192600.0 10840.0   2   7665.0 0.0563 184935.0, 200265.0 0.01
BXH6/TyJ m 118680.0 0.0   1   0.0 0.0 118680.0, 118680.0 -0.36
BXH7/TyJ m 240624.0 0.0   1   0.0 0.0 240624.0, 240624.0 0.25
BXH8/TyJ m 105098.0 0.0   1   0.0 0.0 105098.0, 105098.0 -0.43
BXH9/TyJ m 59743.0 0.0   1   0.0 0.0 59743.0, 59743.0 -0.66
C3H/HeJ m 98022.0 13434.0   2   9499.0 0.137 88523.0, 107521.0 -0.46
C57BL/6J m 352958.0 13841.0   5 6190.0 0.0392 335051.0, 364044.0 0.82
C57L/J m 395928.0 0.0   1   0.0 0.0 395928.0, 395928.0 1.04
C58/J m 1866676.0 0.0   1   0.0 0.0 1866676.0, 1866676.0 8.45
CAST/EiJ m 93328.0 0.0   1   0.0 0.0 93328.0, 93328.0 -0.49
CBA/J m 231307.0 0.0   1   0.0 0.0 231307.0, 231307.0 0.21
CE/J m 203137.0 0.0   1   0.0 0.0 203137.0, 203137.0 0.07
CXB11/HiAJ m 151435.0 33334.0   2   23571.0 0.22 127864.0, 175006.0 -0.2
CXB12/HiAJ m 152788.0 51318.0   2   36287.0 0.336 116501.0, 189076.0 -0.19
CXB13/HiAJ m 115606.0 24759.0   3 14295.0 0.214 87514.0, 134251.0 -0.38
CXB1/ByJ m 105499.0 18251.0   3 10537.0 0.173 84490.0, 117454.0 -0.43
CXB2/ByJ m 105752.0 25564.0   3 14760.0 0.242 83825.0, 133831.0 -0.43
CXB3/ByJ m 123123.0 39330.0   2   27810.0 0.319 95313.0, 150934.0 -0.34
CXB4/ByJ m 143084.0 20031.0   2   14164.0 0.14 128920.0, 157248.0 -0.24
CXB6/ByJ m 132290.0 23939.0   3 13821.0 0.181 106273.0, 153386.0 -0.29
CXB7/ByJ m 122256.0 32204.0   2   22771.0 0.263 99485.0, 145028.0 -0.34
CXB8/HiAJ m 79857.0 16497.0   3 9524.0 0.207 63836.0, 96792.0 -0.56
CXB9/HiAJ m 61310.0 9312.0   3 5376.0 0.152 50622.0, 67669.0 -0.65
DBA/2J m 109498.0 10458.0   4 5229.0 0.0955 95138.0, 118576.0 -0.41
FVB/NJ m 125677.0 0.0   1   0.0 0.0 125677.0, 125677.0 -0.33
I/LnJ m 123453.0 0.0   1   0.0 0.0 123453.0, 123453.0 -0.34
KK/HlJ m 377492.0 0.0   1   0.0 0.0 377492.0, 377492.0 0.94
LG/J m 82020.0 0.0   1   0.0 0.0 82020.0, 82020.0 -0.55
LP/J m 149462.0 0.0   1   0.0 0.0 149462.0, 149462.0 -0.21
MA/MyJ m 141225.0 0.0   1   0.0 0.0 141225.0, 141225.0 -0.25
NOD/ShiLtJ m 69912.0 0.0   1   0.0 0.0 69912.0, 69912.0 -0.61
NON/ShiLtJ m 109639.0 0.0   1   0.0 0.0 109639.0, 109639.0 -0.41
NZW/LacJ m 126858.0 0.0   1   0.0 0.0 126858.0, 126858.0 -0.32
PL/J m 52781.0 0.0   1   0.0 0.0 52781.0, 52781.0 -0.69
RIIIS/J m 118732.0 0.0   1   0.0 0.0 118732.0, 118732.0 -0.36
SEA/GnJ m 90722.0 0.0   1   0.0 0.0 90722.0, 90722.0 -0.5
SJL/J m 78764.0 0.0   1   0.0 0.0 78764.0, 78764.0 -0.56
SM/J m 128970.0 0.0   1   0.0 0.0 128970.0, 128970.0 -0.31
SWR/J m 100201.0 0.0   1   0.0 0.0 100201.0, 100201.0 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 124695.0 42912.786 211904.2737 37485.7263
AXB19b/PgnJ m 92594.75 42912.786 179804.0237 5385.4763
AXB24/PgnJ m 247862.85 42912.786 335072.1237 160653.5763
BALB/cJ m 193715.1 35038.143 264921.1738 122509.0262
BXA16/PgnJ m 222130.7 42912.786 309339.9737 134921.4263
BXD19/TyJ m 192443.15 42912.786 279652.4237 105233.8763
BXD28/TyJ m 156414.1 42912.786 243623.3737 69204.8263
BXH4/TyJ m 192599.9 42912.786 279809.1737 105390.6263
C3H/HeJ m 98022.05 42912.786 185231.3237 10812.7763
C57BL/6J m 352958.48 27140.4289 408114.4676 297802.4924
CXB11/HiAJ m 151434.95 42912.786 238644.2237 64225.6763
CXB12/HiAJ m 152788.25 42912.786 239997.5237 65578.9763
CXB13/HiAJ m 115605.6333 35038.143 186811.7071 44399.5596
CXB1/ByJ m 105498.6667 35038.143 176704.7404 34292.5929
CXB2/ByJ m 105752.2667 35038.143 176958.3404 34546.1929
CXB3/ByJ m 123123.05 42912.786 210332.3237 35913.7763
CXB4/ByJ m 143084.4 42912.786 230293.6737 55875.1263
CXB6/ByJ m 132290.4667 35038.143 203496.5404 61084.3929
CXB7/ByJ m 122256.05 42912.786 209465.3237 35046.7763
CXB8/HiAJ m 79857.1 35038.143 151063.1738 8651.0262
CXB9/HiAJ m 61310.4667 35038.143 132516.5404 0.0
DBA/2J m 109498.35 30343.922 171164.6188 47832.0812




  GWAS USING LINEAR MIXED MODELS