Project measure / variable:   HMDPpheno6   AHB

ID, description, units MPD:50109   AHB   liver 2-hydroxybutyrate (AHB) (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   99 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 2-hydroxybutyrate (AHB) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested99 strains
Mean of the strain means196391   None
Median of the strain means148517   None
SD of the strain means± 128300
Coefficient of variation (CV)0.653
Min–max range of strain means33632   –   635430   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 459664434500.982 22983221725.0491 8.415 < 0.0001
Residuals 31 84667579787.692 2731212251.2159


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 93411.0 0.0   1   0.0 0.0 93411.0, 93411.0 -0.8
A/J m 240444.0 19616.0   2   13870.0 0.0816 226574.0, 254315.0 0.34
AKR/J m 125447.0 0.0   1   0.0 0.0 125447.0, 125447.0 -0.55
AXB10/PgnJ m 127941.0 0.0   1   0.0 0.0 127941.0, 127941.0 -0.53
AXB12/PgnJ m 170218.0 0.0   1   0.0 0.0 170218.0, 170218.0 -0.2
AXB13/PgnJ m 134119.0 0.0   1   0.0 0.0 134119.0, 134119.0 -0.49
AXB15/PgnJ m 270326.0 0.0   1   0.0 0.0 270326.0, 270326.0 0.58
AXB19a/PgnJ m 300851.0 0.0   1   0.0 0.0 300851.0, 300851.0 0.81
AXB19b/PgnJ m 135463.0 4734.0   2   3347.0 0.0349 132116.0, 138810.0 -0.47
AXB19/PgnJ m 128032.0 0.0   1   0.0 0.0 128032.0, 128032.0 -0.53
AXB1/PgnJ m 635430.0 0.0   1   0.0 0.0 635430.0, 635430.0 3.42
AXB23/PgnJ m 97157.0 0.0   1   0.0 0.0 97157.0, 97157.0 -0.77
AXB24/PgnJ m 128225.0 71742.0   2   50729.0 0.56 77495.0, 178954.0 -0.53
AXB2/PgnJ m 337611.0 0.0   1   0.0 0.0 337611.0, 337611.0 1.1
AXB4/PgnJ m 376462.0 0.0   1   0.0 0.0 376462.0, 376462.0 1.4
AXB5/PgnJ m 367226.0 0.0   1   0.0 0.0 367226.0, 367226.0 1.33
AXB6/PgnJ m 277582.0 0.0   1   0.0 0.0 277582.0, 277582.0 0.63
AXB8/PgnJ m 342230.0 0.0   1   0.0 0.0 342230.0, 342230.0 1.14
BALB/cJ m 153674.0 47607.0   2   33663.0 0.31 120010.0, 187337.0 -0.33
BUB/BnJ m 178634.0 0.0   1   0.0 0.0 178634.0, 178634.0 -0.14
BXA11/PgnJ m 76021.0 0.0   1   0.0 0.0 76021.0, 76021.0 -0.94
BXA12/PgnJ m 428156.0 0.0   1   0.0 0.0 428156.0, 428156.0 1.81
BXA13/PgnJ m 101807.0 0.0   1   0.0 0.0 101807.0, 101807.0 -0.74
BXA14/PgnJ m 419109.0 0.0   1   0.0 0.0 419109.0, 419109.0 1.74
BXA16/PgnJ m 126822.0 46968.0   2   33211.0 0.37 93611.0, 160034.0 -0.54
BXA1/PgnJ m 112994.0 0.0   1   0.0 0.0 112994.0, 112994.0 -0.65
BXA24/PgnJ m 312745.0 0.0   1   0.0 0.0 312745.0, 312745.0 0.91
BXA25/PgnJ m 111342.0 0.0   1   0.0 0.0 111342.0, 111342.0 -0.66
BXA26/PgnJ m 509361.0 0.0   1   0.0 0.0 509361.0, 509361.0 2.44
BXA2/PgnJ m 175912.0 0.0   1   0.0 0.0 175912.0, 175912.0 -0.16
BXA4/PgnJ m 571075.0 0.0   1   0.0 0.0 571075.0, 571075.0 2.92
BXA7/PgnJ m 141410.0 0.0   1   0.0 0.0 141410.0, 141410.0 -0.43
BXA8/PgnJ m 166051.0 0.0   1   0.0 0.0 166051.0, 166051.0 -0.24
BXD11/TyJ m 93673.0 0.0   1   0.0 0.0 93673.0, 93673.0 -0.8
BXD13/TyJ m 110786.0 0.0   1   0.0 0.0 110786.0, 110786.0 -0.67
BXD14/TyJ m 267060.0 0.0   1   0.0 0.0 267060.0, 267060.0 0.55
BXD18/TyJ m 53281.0 0.0   1   0.0 0.0 53281.0, 53281.0 -1.12
BXD19/TyJ m 117866.0 61382.0   2   43404.0 0.521 74463.0, 161270.0 -0.61
BXD20/TyJ m 120549.0 0.0   1   0.0 0.0 120549.0, 120549.0 -0.59
BXD21/TyJ m 47590.0 0.0   1   0.0 0.0 47590.0, 47590.0 -1.16
BXD22/TyJ m 86073.0 0.0   1   0.0 0.0 86073.0, 86073.0 -0.86
BXD24/TyJ m 93675.0 0.0   1   0.0 0.0 93675.0, 93675.0 -0.8
BXD24/TyJ-Cep290rd16/J m 119898.0 0.0   1   0.0 0.0 119898.0, 119898.0 -0.6
BXD28/TyJ m 161821.0 6866.0   2   4855.0 0.0424 156966.0, 166676.0 -0.27
BXD2/TyJ m 170674.0 0.0   1   0.0 0.0 170674.0, 170674.0 -0.2
BXD32/TyJ m 400843.0 0.0   1   0.0 0.0 400843.0, 400843.0 1.59
BXD33/TyJ m 562501.0 0.0   1   0.0 0.0 562501.0, 562501.0 2.85
BXD34/TyJ m 177264.0 0.0   1   0.0 0.0 177264.0, 177264.0 -0.15
BXD36/TyJ m 108684.0 0.0   1   0.0 0.0 108684.0, 108684.0 -0.68
BXD38/TyJ m 98343.0 0.0   1   0.0 0.0 98343.0, 98343.0 -0.76
BXD39/TyJ m 63031.0 0.0   1   0.0 0.0 63031.0, 63031.0 -1.04
BXD40/TyJ m 131436.0 0.0   1   0.0 0.0 131436.0, 131436.0 -0.51
BXD5/TyJ m 244590.0 0.0   1   0.0 0.0 244590.0, 244590.0 0.38
BXD6/TyJ m 156193.0 0.0   1   0.0 0.0 156193.0, 156193.0 -0.31
BXD8/TyJ m 115722.0 0.0   1   0.0 0.0 115722.0, 115722.0 -0.63
BXD9/TyJ m 83883.0 0.0   1   0.0 0.0 83883.0, 83883.0 -0.88
BXH10/TyJ m 136229.0 0.0   1   0.0 0.0 136229.0, 136229.0 -0.47
BXH19/TyJ m 231728.0 0.0   1   0.0 0.0 231728.0, 231728.0 0.28
BXH20/KccJ m 132332.0 0.0   1   0.0 0.0 132332.0, 132332.0 -0.5
BXH22/KccJ m 85185.0 0.0   1   0.0 0.0 85185.0, 85185.0 -0.87
BXH2/TyJ m 175403.0 0.0   1   0.0 0.0 175403.0, 175403.0 -0.16
BXH4/TyJ m 104839.0 46252.0   2   32705.0 0.441 72134.0, 137544.0 -0.71
BXH6/TyJ m 224632.0 0.0   1   0.0 0.0 224632.0, 224632.0 0.22
BXH7/TyJ m 116372.0 0.0   1   0.0 0.0 116372.0, 116372.0 -0.62
BXH8/TyJ m 361439.0 0.0   1   0.0 0.0 361439.0, 361439.0 1.29
BXH9/TyJ m 96220.0 0.0   1   0.0 0.0 96220.0, 96220.0 -0.78
C3H/HeJ m 170621.0 42323.0   2   29927.0 0.248 140694.0, 200548.0 -0.2
C57BL/6J m 344185.0 78400.0   5 35062.0 0.228 231872.0, 440084.0 1.15
C57L/J m 194508.0 0.0   1   0.0 0.0 194508.0, 194508.0 -0.01
C58/J m 553349.0 0.0   1   0.0 0.0 553349.0, 553349.0 2.78
CAST/EiJ m 73837.0 0.0   1   0.0 0.0 73837.0, 73837.0 -0.96
CBA/J m 95792.0 0.0   1   0.0 0.0 95792.0, 95792.0 -0.78
CE/J m 148517.0 0.0   1   0.0 0.0 148517.0, 148517.0 -0.37
CXB11/HiAJ m 70670.0 0.0   1   0.0 0.0 70670.0, 70670.0 -0.98
CXB12/HiAJ m 335684.0 11270.0   2   7969.0 0.0336 327716.0, 343653.0 1.09
CXB13/HiAJ m 396771.0 73755.0   3 42583.0 0.186 311626.0, 440924.0 1.56
CXB1/ByJ m 217700.0 23039.0   3 13302.0 0.106 201417.0, 244061.0 0.17
CXB2/ByJ m 205495.0 60743.0   3 35070.0 0.296 136434.0, 250640.0 0.07
CXB3/ByJ m 272171.0 68118.0   2   48167.0 0.25 224004.0, 320338.0 0.59
CXB4/ByJ m 208175.0 19994.0   2   14138.0 0.096 194038.0, 222313.0 0.09
CXB6/ByJ m 339533.0 68416.0   3 39500.0 0.201 282164.0, 415252.0 1.12
CXB7/ByJ m 199979.0 45783.0   2   32373.0 0.229 167606.0, 232352.0 0.03
CXB8/HiAJ m 199182.0 55849.0   3 32245.0 0.28 157422.0, 262620.0 0.02
CXB9/HiAJ m 161672.0 4657.0   3 2689.0 0.0288 157056.0, 166370.0 -0.27
DBA/2J m 51711.0 6433.0   3 3714.0 0.124 45456.0, 58308.0 -1.13
FVB/NJ m 217920.0 0.0   1   0.0 0.0 217920.0, 217920.0 0.17
I/LnJ m 100561.0 0.0   1   0.0 0.0 100561.0, 100561.0 -0.75
KK/HlJ m 101401.0 0.0   1   0.0 0.0 101401.0, 101401.0 -0.74
LG/J m 33632.0 0.0   1   0.0 0.0 33632.0, 33632.0 -1.27
LP/J m 147582.0 0.0   1   0.0 0.0 147582.0, 147582.0 -0.38
MA/MyJ m 377077.0 0.0   1   0.0 0.0 377077.0, 377077.0 1.41
NOD/ShiLtJ m 150996.0 0.0   1   0.0 0.0 150996.0, 150996.0 -0.35
NON/ShiLtJ m 218828.0 0.0   1   0.0 0.0 218828.0, 218828.0 0.17
NZW/LacJ m 132131.0 0.0   1   0.0 0.0 132131.0, 132131.0 -0.5
PL/J m 130164.0 0.0   1   0.0 0.0 130164.0, 130164.0 -0.52
RIIIS/J m 109150.0 0.0   1   0.0 0.0 109150.0, 109150.0 -0.68
SEA/GnJ m 90274.0 0.0   1   0.0 0.0 90274.0, 90274.0 -0.83
SJL/J m 145653.0 0.0   1   0.0 0.0 145653.0, 145653.0 -0.4
SWR/J m 124638.0 0.0   1   0.0 0.0 124638.0, 124638.0 -0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 240444.5 36954.1084 315812.9009 165076.0991
AXB19b/PgnJ m 135463.2 36954.1084 210831.6009 60094.7991
AXB24/PgnJ m 128224.85 36954.1084 203593.2509 52856.4491
BALB/cJ m 153673.95 36954.1084 229042.3509 78305.5491
BXA16/PgnJ m 126822.45 36954.1084 202190.8509 51454.0491
BXD19/TyJ m 117866.15 36954.1084 193234.5509 42497.7491
BXD28/TyJ m 161821.0 36954.1084 237189.4009 86452.5991
BXH4/TyJ m 104838.6 36954.1084 180207.0009 29470.1991
C3H/HeJ m 170620.85 36954.1084 245989.2509 95252.4491
C57BL/6J m 344184.74 23371.8303 391851.9021 296517.5779
CXB12/HiAJ m 335684.35 36954.1084 411052.7509 260315.9491
CXB13/HiAJ m 396771.3667 30172.9031 458309.4083 335233.325
CXB1/ByJ m 217699.9667 30172.9031 279238.0083 156161.925
CXB2/ByJ m 205494.6 30172.9031 267032.6417 143956.5583
CXB3/ByJ m 272171.2 36954.1084 347539.6009 196802.7991
CXB4/ByJ m 208175.45 36954.1084 283543.8509 132807.0491
CXB6/ByJ m 339533.2667 30172.9031 401071.3083 277995.225
CXB7/ByJ m 199978.95 36954.1084 275347.3509 124610.5491
CXB8/HiAJ m 199181.5333 30172.9031 260719.575 137643.4917
CXB9/HiAJ m 161671.5667 30172.9031 223209.6083 100133.525
DBA/2J m 51710.7667 30172.9031 113248.8083 0.0




  GWAS USING LINEAR MIXED MODELS