Project measure / variable:   HMDPpheno6   diMe_Gly

ID, description, units MPD:50128   diMe_Gly   liver dimethylglycine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   96 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver dimethylglycine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested96 strains
Mean of the strain means261771   None
Median of the strain means227636   None
SD of the strain means± 139257
Coefficient of variation (CV)0.532
Min–max range of strain means69477   –   809774   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 700994980754.68 35049749037.734 2.8605 0.0042
Residuals 31 379844772284.399 12253057170.4645


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 194481.0 0.0   1   0.0 0.0 194481.0, 194481.0 -0.48
A/J m 416378.0 126230.0   2   89258.0 0.303 327120.0, 505636.0 1.11
AKR/J m 122980.0 0.0   1   0.0 0.0 122980.0, 122980.0 -1.0
AXB10/PgnJ m 230203.0 0.0   1   0.0 0.0 230203.0, 230203.0 -0.23
AXB12/PgnJ m 264013.0 0.0   1   0.0 0.0 264013.0, 264013.0 0.02
AXB15/PgnJ m 174647.0 0.0   1   0.0 0.0 174647.0, 174647.0 -0.63
AXB19a/PgnJ m 592157.0 0.0   1   0.0 0.0 592157.0, 592157.0 2.37
AXB19b/PgnJ m 300068.0 65039.0   2   45990.0 0.217 254078.0, 346057.0 0.28
AXB19/PgnJ m 279878.0 0.0   1   0.0 0.0 279878.0, 279878.0 0.13
AXB1/PgnJ m 411779.0 0.0   1   0.0 0.0 411779.0, 411779.0 1.08
AXB24/PgnJ m 178740.0 0.0   1   0.0 0.0 178740.0, 178740.0 -0.6
AXB2/PgnJ m 424091.0 0.0   1   0.0 0.0 424091.0, 424091.0 1.17
AXB4/PgnJ m 417290.0 0.0   1   0.0 0.0 417290.0, 417290.0 1.12
AXB5/PgnJ m 309467.0 0.0   1   0.0 0.0 309467.0, 309467.0 0.34
AXB6/PgnJ m 216421.0 0.0   1   0.0 0.0 216421.0, 216421.0 -0.33
AXB8/PgnJ m 224223.0 0.0   1   0.0 0.0 224223.0, 224223.0 -0.27
BALB/cJ m 214269.0 28598.0   2   20222.0 0.133 194047.0, 234491.0 -0.34
BTBR T+ Itpr3tf/J m 238604.0 0.0   1   0.0 0.0 238604.0, 238604.0 -0.17
BUB/BnJ m 233234.0 0.0   1   0.0 0.0 233234.0, 233234.0 -0.2
BXA11/PgnJ m 99920.0 0.0   1   0.0 0.0 99920.0, 99920.0 -1.16
BXA12/PgnJ m 258836.0 0.0   1   0.0 0.0 258836.0, 258836.0 -0.02
BXA13/PgnJ m 256048.0 0.0   1   0.0 0.0 256048.0, 256048.0 -0.04
BXA14/PgnJ m 734959.0 0.0   1   0.0 0.0 734959.0, 734959.0 3.4
BXA16/PgnJ m 371003.0 200258.0   2   141604.0 0.54 229399.0, 512606.0 0.78
BXA1/PgnJ m 114022.0 0.0   1   0.0 0.0 114022.0, 114022.0 -1.06
BXA24/PgnJ m 206268.0 0.0   1   0.0 0.0 206268.0, 206268.0 -0.4
BXA25/PgnJ m 147900.0 0.0   1   0.0 0.0 147900.0, 147900.0 -0.82
BXA26/PgnJ m 258728.0 0.0   1   0.0 0.0 258728.0, 258728.0 -0.02
BXA2/PgnJ m 281806.0 0.0   1   0.0 0.0 281806.0, 281806.0 0.14
BXA4/PgnJ m 227128.0 0.0   1   0.0 0.0 227128.0, 227128.0 -0.25
BXA7/PgnJ m 402448.0 0.0   1   0.0 0.0 402448.0, 402448.0 1.01
BXA8/PgnJ m 175110.0 0.0   1   0.0 0.0 175110.0, 175110.0 -0.62
BXD11/TyJ m 140828.0 0.0   1   0.0 0.0 140828.0, 140828.0 -0.87
BXD12/TyJ m 232321.0 0.0   1   0.0 0.0 232321.0, 232321.0 -0.21
BXD14/TyJ m 207718.0 0.0   1   0.0 0.0 207718.0, 207718.0 -0.39
BXD15/TyJ m 146661.0 0.0   1   0.0 0.0 146661.0, 146661.0 -0.83
BXD18/TyJ m 279615.0 0.0   1   0.0 0.0 279615.0, 279615.0 0.13
BXD19/TyJ m 228143.0 7608.0   2   5380.0 0.0333 222763.0, 233522.0 -0.24
BXD1/TyJ m 268549.0 0.0   1   0.0 0.0 268549.0, 268549.0 0.05
BXD20/TyJ m 345806.0 0.0   1   0.0 0.0 345806.0, 345806.0 0.6
BXD21/TyJ m 207613.0 0.0   1   0.0 0.0 207613.0, 207613.0 -0.39
BXD22/TyJ m 221952.0 0.0   1   0.0 0.0 221952.0, 221952.0 -0.29
BXD24/TyJ m 104811.0 0.0   1   0.0 0.0 104811.0, 104811.0 -1.13
BXD28/TyJ m 208830.0 16466.0   2   11643.0 0.0789 197186.0, 220473.0 -0.38
BXD29-Tlr4lps-2J/J m 195559.0 0.0   1   0.0 0.0 195559.0, 195559.0 -0.48
BXD2/TyJ m 223251.0 0.0   1   0.0 0.0 223251.0, 223251.0 -0.28
BXD32/TyJ m 244281.0 0.0   1   0.0 0.0 244281.0, 244281.0 -0.13
BXD33/TyJ m 486321.0 0.0   1   0.0 0.0 486321.0, 486321.0 1.61
BXD34/TyJ m 147049.0 0.0   1   0.0 0.0 147049.0, 147049.0 -0.82
BXD39/TyJ m 163085.0 0.0   1   0.0 0.0 163085.0, 163085.0 -0.71
BXD40/TyJ m 239916.0 0.0   1   0.0 0.0 239916.0, 239916.0 -0.16
BXD42/TyJ m 152823.0 0.0   1   0.0 0.0 152823.0, 152823.0 -0.78
BXD5/TyJ m 143681.0 0.0   1   0.0 0.0 143681.0, 143681.0 -0.85
BXD6/TyJ m 379250.0 0.0   1   0.0 0.0 379250.0, 379250.0 0.84
BXD8/TyJ m 347744.0 0.0   1   0.0 0.0 347744.0, 347744.0 0.62
BXH10/TyJ m 112123.0 0.0   1   0.0 0.0 112123.0, 112123.0 -1.07
BXH19/TyJ m 167107.0 0.0   1   0.0 0.0 167107.0, 167107.0 -0.68
BXH20/KccJ m 195457.0 0.0   1   0.0 0.0 195457.0, 195457.0 -0.48
BXH22/KccJ m 163863.0 0.0   1   0.0 0.0 163863.0, 163863.0 -0.7
BXH2/TyJ m 183285.0 0.0   1   0.0 0.0 183285.0, 183285.0 -0.56
BXH4/TyJ m 201083.0 10724.0   2   7583.0 0.0533 193500.0, 208666.0 -0.44
BXH6/TyJ m 101502.0 0.0   1   0.0 0.0 101502.0, 101502.0 -1.15
BXH7/TyJ m 398245.0 0.0   1   0.0 0.0 398245.0, 398245.0 0.98
BXH9/TyJ m 103754.0 0.0   1   0.0 0.0 103754.0, 103754.0 -1.13
C3H/HeJ m 127982.0 84922.0   2   60049.0 0.664 67933.0, 188032.0 -0.96
C57BL/6J m 360078.0 83222.0   5 37218.0 0.231 277898.0, 489218.0 0.71
C57L/J m 116339.0 0.0   1   0.0 0.0 116339.0, 116339.0 -1.04
C58/J m 696089.0 0.0   1   0.0 0.0 696089.0, 696089.0 3.12
CAST/EiJ m 388575.0 0.0   1   0.0 0.0 388575.0, 388575.0 0.91
CE/J m 166050.0 0.0   1   0.0 0.0 166050.0, 166050.0 -0.69
CXB11/HiAJ m 167526.0 95031.0   2   67197.0 0.567 100329.0, 234724.0 -0.68
CXB12/HiAJ m 303263.0 170468.0   2   120539.0 0.562 182724.0, 423803.0 0.3
CXB13/HiAJ m 549500.0 227457.0   3 131322.0 0.414 360595.0, 801981.0 2.07
CXB1/ByJ m 473660.0 183149.0   3 105741.0 0.387 299112.0, 664342.0 1.52
CXB2/ByJ m 469469.0 158103.0   3 91281.0 0.337 346783.0, 647891.0 1.49
CXB3/ByJ m 162466.0 22884.0   2   16181.0 0.141 146284.0, 178647.0 -0.71
CXB4/ByJ m 182752.0 45988.0   2   32519.0 0.252 150233.0, 215271.0 -0.57
CXB6/ByJ m 270498.0 85494.0   3 49360.0 0.316 178685.0, 347821.0 0.06
CXB7/ByJ m 269690.0 17664.0   2   12490.0 0.0655 257199.0, 282180.0 0.06
CXB8/HiAJ m 318665.0 44060.0   3 25438.0 0.138 276779.0, 364618.0 0.41
CXB9/HiAJ m 270979.0 32196.0   2   22766.0 0.119 248213.0, 293745.0 0.07
DBA/2J m 183395.0 27494.0   4 13747.0 0.15 153843.0, 220345.0 -0.56
FVB/NJ m 809774.0 0.0   1   0.0 0.0 809774.0, 809774.0 3.94
I/LnJ m 383760.0 0.0   1   0.0 0.0 383760.0, 383760.0 0.88
KK/HlJ m 190078.0 0.0   1   0.0 0.0 190078.0, 190078.0 -0.51
LG/J m 69477.0 0.0   1   0.0 0.0 69477.0, 69477.0 -1.38
LP/J m 332173.0 0.0   1   0.0 0.0 332173.0, 332173.0 0.51
MA/MyJ m 158002.0 0.0   1   0.0 0.0 158002.0, 158002.0 -0.75
NOD/ShiLtJ m 237645.0 0.0   1   0.0 0.0 237645.0, 237645.0 -0.17
NON/ShiLtJ m 328229.0 0.0   1   0.0 0.0 328229.0, 328229.0 0.48
NZW/LacJ m 80086.0 0.0   1   0.0 0.0 80086.0, 80086.0 -1.3
PL/J m 136783.0 0.0   1   0.0 0.0 136783.0, 136783.0 -0.9
SEA/GnJ m 141094.0 0.0   1   0.0 0.0 141094.0, 141094.0 -0.87
SJL/J m 400597.0 0.0   1   0.0 0.0 400597.0, 400597.0 1.0
SM/J m 206450.0 0.0   1   0.0 0.0 206450.0, 206450.0 -0.4
SWR/J m 259537.0 0.0   1   0.0 0.0 259537.0, 259537.0 -0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 416378.0 78272.1444 576015.0909 256740.9091
AXB19b/PgnJ m 300067.5 78272.1444 459704.5909 140430.4091
BALB/cJ m 214268.85 78272.1444 373905.9409 54631.7591
BXA16/PgnJ m 371002.8 78272.1444 530639.8909 211365.7091
BXD19/TyJ m 228142.7 78272.1444 387779.7909 68505.6091
BXD28/TyJ m 208829.8 78272.1444 368466.8909 49192.7091
BXH4/TyJ m 201083.0 78272.1444 360720.0909 41445.9091
C3H/HeJ m 127982.25 78272.1444 287619.3409 0.0
C57BL/6J m 360077.8 49503.6507 461041.1613 259114.4387
CXB11/HiAJ m 167526.4 78272.1444 327163.4909 7889.3091
CXB12/HiAJ m 303263.3 78272.1444 462900.3909 143626.2091
CXB13/HiAJ m 549499.9333 63908.9383 679843.0723 419156.7944
CXB1/ByJ m 473659.7 63908.9383 604002.8389 343316.5611
CXB2/ByJ m 469468.7333 63908.9383 599811.8723 339125.5944
CXB3/ByJ m 162465.85 78272.1444 322102.9409 2828.7591
CXB4/ByJ m 182752.15 78272.1444 342389.2409 23115.0591
CXB6/ByJ m 270497.8333 63908.9383 400840.9723 140154.6944
CXB7/ByJ m 269689.8 78272.1444 429326.8909 110052.7091
CXB8/HiAJ m 318665.0667 63908.9383 449008.2056 188321.9277
CXB9/HiAJ m 270978.85 78272.1444 430615.9409 111341.7591
DBA/2J m 183394.825 55346.7641 296275.2945 70514.3555




  GWAS USING LINEAR MIXED MODELS