Project measure / variable:   HMDPpheno6   guanidino

ID, description, units MPD:50136   guanidino   liver 4-guanidinobutanoate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   94 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 4-guanidinobutanoate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested94 strains
Mean of the strain means62635   None
Median of the strain means42698   None
SD of the strain means± 84133
Coefficient of variation (CV)1.34
Min–max range of strain means17931   –   588492   None
Mean sample size per strain1.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 16 2848324184.2728 178020261.517 0.8185 0.6556
Residuals 26 5654837627.15 217493754.8904


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 48176.0 0.0   1   0.0 0.0 48176.0, 48176.0 -0.17
A/J m 55273.0 5905.0   2   4175.0 0.107 51098.0, 59448.0 -0.09
AKR/J m 32983.0 0.0   1   0.0 0.0 32983.0, 32983.0 -0.35
AXB10/PgnJ m 22848.0 0.0   1   0.0 0.0 22848.0, 22848.0 -0.47
AXB12/PgnJ m 46347.0 0.0   1   0.0 0.0 46347.0, 46347.0 -0.19
AXB13/PgnJ m 49464.0 0.0   1   0.0 0.0 49464.0, 49464.0 -0.16
AXB15/PgnJ m 40485.0 0.0   1   0.0 0.0 40485.0, 40485.0 -0.26
AXB19a/PgnJ m 84384.0 0.0   1   0.0 0.0 84384.0, 84384.0 0.26
AXB19b/PgnJ m 53687.0 22697.0   2   16049.0 0.423 37638.0, 69736.0 -0.11
AXB19/PgnJ m 108953.0 0.0   1   0.0 0.0 108953.0, 108953.0 0.55
AXB1/PgnJ m 53177.0 0.0   1   0.0 0.0 53177.0, 53177.0 -0.11
AXB23/PgnJ m 27108.0 0.0   1   0.0 0.0 27108.0, 27108.0 -0.42
AXB24/PgnJ m 25313.0 0.0   1   0.0 0.0 25313.0, 25313.0 -0.44
AXB2/PgnJ m 33150.0 0.0   1   0.0 0.0 33150.0, 33150.0 -0.35
AXB4/PgnJ m 17931.0 0.0   1   0.0 0.0 17931.0, 17931.0 -0.53
AXB8/PgnJ m 23028.0 0.0   1   0.0 0.0 23028.0, 23028.0 -0.47
BALB/cJ m 56829.0 19057.0   3 11003.0 0.335 41164.0, 78045.0 -0.07
BTBR T+ Itpr3tf/J m 42632.0 0.0   1   0.0 0.0 42632.0, 42632.0 -0.24
BUB/BnJ m 429857.0 0.0   1   0.0 0.0 429857.0, 429857.0 4.36
BXA11/PgnJ m 26131.0 0.0   1   0.0 0.0 26131.0, 26131.0 -0.43
BXA12/PgnJ m 35430.0 0.0   1   0.0 0.0 35430.0, 35430.0 -0.32
BXA13/PgnJ m 21745.0 0.0   1   0.0 0.0 21745.0, 21745.0 -0.49
BXA14/PgnJ m 417572.0 0.0   1   0.0 0.0 417572.0, 417572.0 4.22
BXA16/PgnJ m 76200.0 0.0   1   0.0 0.0 76200.0, 76200.0 0.16
BXA1/PgnJ m 38435.0 0.0   1   0.0 0.0 38435.0, 38435.0 -0.29
BXA24/PgnJ m 25720.0 0.0   1   0.0 0.0 25720.0, 25720.0 -0.44
BXA25/PgnJ m 60422.0 0.0   1   0.0 0.0 60422.0, 60422.0 -0.03
BXA26/PgnJ m 18979.0 0.0   1   0.0 0.0 18979.0, 18979.0 -0.52
BXA2/PgnJ m 37610.0 0.0   1   0.0 0.0 37610.0, 37610.0 -0.3
BXA4/PgnJ m 41558.0 0.0   1   0.0 0.0 41558.0, 41558.0 -0.25
BXA7/PgnJ m 56587.0 0.0   1   0.0 0.0 56587.0, 56587.0 -0.07
BXA8/PgnJ m 57900.0 0.0   1   0.0 0.0 57900.0, 57900.0 -0.06
BXD11/TyJ m 49308.0 0.0   1   0.0 0.0 49308.0, 49308.0 -0.16
BXD12/TyJ m 280818.0 0.0   1   0.0 0.0 280818.0, 280818.0 2.59
BXD13/TyJ m 26078.0 0.0   1   0.0 0.0 26078.0, 26078.0 -0.43
BXD14/TyJ m 41836.0 0.0   1   0.0 0.0 41836.0, 41836.0 -0.25
BXD15/TyJ m 26765.0 0.0   1   0.0 0.0 26765.0, 26765.0 -0.43
BXD18/TyJ m 30444.0 0.0   1   0.0 0.0 30444.0, 30444.0 -0.38
BXD19/TyJ m 42493.0 19270.0   2   13626.0 0.454 28866.0, 56119.0 -0.24
BXD1/TyJ m 47224.0 0.0   1   0.0 0.0 47224.0, 47224.0 -0.18
BXD20/TyJ m 60950.0 0.0   1   0.0 0.0 60950.0, 60950.0 -0.02
BXD21/TyJ m 37032.0 0.0   1   0.0 0.0 37032.0, 37032.0 -0.3
BXD22/TyJ m 37452.0 0.0   1   0.0 0.0 37452.0, 37452.0 -0.3
BXD24/TyJ m 61391.0 0.0   1   0.0 0.0 61391.0, 61391.0 -0.01
BXD24/TyJ-Cep290rd16/J m 42234.0 0.0   1   0.0 0.0 42234.0, 42234.0 -0.24
BXD28/TyJ m 26590.0 0.0   1   0.0 0.0 26590.0, 26590.0 -0.43
BXD29-Tlr4lps-2J/J m 55073.0 0.0   1   0.0 0.0 55073.0, 55073.0 -0.09
BXD2/TyJ m 52794.0 0.0   1   0.0 0.0 52794.0, 52794.0 -0.12
BXD32/TyJ m 66906.0 0.0   1   0.0 0.0 66906.0, 66906.0 0.05
BXD33/TyJ m 62015.0 0.0   1   0.0 0.0 62015.0, 62015.0 -0.01
BXD34/TyJ m 74026.0 0.0   1   0.0 0.0 74026.0, 74026.0 0.14
BXD38/TyJ m 48241.0 0.0   1   0.0 0.0 48241.0, 48241.0 -0.17
BXD39/TyJ m 44773.0 0.0   1   0.0 0.0 44773.0, 44773.0 -0.21
BXD42/TyJ m 58256.0 0.0   1   0.0 0.0 58256.0, 58256.0 -0.05
BXD5/TyJ m 57349.0 0.0   1   0.0 0.0 57349.0, 57349.0 -0.06
BXD6/TyJ m 22875.0 0.0   1   0.0 0.0 22875.0, 22875.0 -0.47
BXH10/TyJ m 55423.0 0.0   1   0.0 0.0 55423.0, 55423.0 -0.09
BXH19/TyJ m 84176.0 0.0   1   0.0 0.0 84176.0, 84176.0 0.26
BXH20/KccJ m 56377.0 0.0   1   0.0 0.0 56377.0, 56377.0 -0.07
BXH2/TyJ m 19658.0 0.0   1   0.0 0.0 19658.0, 19658.0 -0.51
BXH4/TyJ m 36634.0 13328.0   2   9424.0 0.364 27210.0, 46058.0 -0.31
BXH6/TyJ m 186533.0 0.0   1   0.0 0.0 186533.0, 186533.0 1.47
C3H/HeJ m 43645.0 1911.0   2   1351.0 0.0438 42294.0, 44996.0 -0.23
C57BL/6J m 37584.0 7575.0   4 3787.0 0.202 27924.0, 46409.0 -0.3
C57L/J m 49488.0 0.0   1   0.0 0.0 49488.0, 49488.0 -0.16
C58/J m 96532.0 0.0   1   0.0 0.0 96532.0, 96532.0 0.4
CAST/EiJ m 588492.0 0.0   1   0.0 0.0 588492.0, 588492.0 6.25
CE/J m 33504.0 0.0   1   0.0 0.0 33504.0, 33504.0 -0.35
CXB11/HiAJ m 47892.0 40607.0   2   28713.0 0.848 19178.0, 76605.0 -0.18
CXB12/HiAJ m 18780.0 0.0   1   0.0 0.0 18780.0, 18780.0 -0.52
CXB13/HiAJ m 31719.0 12187.0   3 7036.0 0.384 17975.0, 41207.0 -0.37
CXB1/ByJ m 42110.0 4189.0   3 2418.0 0.0995 37890.0, 46267.0 -0.24
CXB2/ByJ m 41288.0 7478.0   3 4317.0 0.181 35179.0, 49628.0 -0.25
CXB3/ByJ m 31296.0 6031.0   2   4264.0 0.193 27031.0, 35560.0 -0.37
CXB4/ByJ m 28878.0 8825.0   2   6240.0 0.306 22638.0, 35118.0 -0.4
CXB6/ByJ m 41558.0 18483.0   3 10671.0 0.445 30237.0, 62887.0 -0.25
CXB7/ByJ m 20334.0 0.0   1   0.0 0.0 20334.0, 20334.0 -0.5
CXB8/HiAJ m 42550.0 16054.0   3 9269.0 0.377 26657.0, 58760.0 -0.24
CXB9/HiAJ m 39888.0 11164.0   2   7894.0 0.28 31994.0, 47782.0 -0.27
DBA/2J m 29252.0 7850.0   3 4532.0 0.268 20758.0, 36241.0 -0.4
FVB/NJ m 56716.0 0.0   1   0.0 0.0 56716.0, 56716.0 -0.07
I/LnJ m 43261.0 0.0   1   0.0 0.0 43261.0, 43261.0 -0.23
KK/HlJ m 80929.0 0.0   1   0.0 0.0 80929.0, 80929.0 0.22
LG/J m 44942.0 0.0   1   0.0 0.0 44942.0, 44942.0 -0.21
LP/J m 52235.0 0.0   1   0.0 0.0 52235.0, 52235.0 -0.12
MA/MyJ m 26790.0 0.0   1   0.0 0.0 26790.0, 26790.0 -0.43
NOD/ShiLtJ m 27057.0 0.0   1   0.0 0.0 27057.0, 27057.0 -0.42
NON/ShiLtJ m 42764.0 0.0   1   0.0 0.0 42764.0, 42764.0 -0.24
NZW/LacJ m 27126.0 0.0   1   0.0 0.0 27126.0, 27126.0 -0.42
PL/J m 91435.0 0.0   1   0.0 0.0 91435.0, 91435.0 0.34
RIIIS/J m 33112.0 0.0   1   0.0 0.0 33112.0, 33112.0 -0.35
SJL/J m 34036.0 0.0   1   0.0 0.0 34036.0, 34036.0 -0.34
SM/J m 53723.0 0.0   1   0.0 0.0 53723.0, 53723.0 -0.11
SWR/J m 51133.0 0.0   1   0.0 0.0 51133.0, 51133.0 -0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 55273.05 10428.1771 76708.475 33837.625
AXB19b/PgnJ m 53686.85 10428.1771 75122.275 32251.425
BALB/cJ m 56828.6667 8514.5709 74330.6179 39326.7154
BXD19/TyJ m 42492.8 10428.1771 63928.225 21057.375
BXH4/TyJ m 36634.15 10428.1771 58069.575 15198.725
C3H/HeJ m 43644.85 10428.1771 65080.275 22209.425
C57BL/6J m 37584.1 7373.8347 52741.2344 22426.9656
CXB11/HiAJ m 47891.65 10428.1771 69327.075 26456.225
CXB13/HiAJ m 31719.1667 8514.5709 49221.1179 14217.2154
CXB1/ByJ m 42110.2667 8514.5709 59612.2179 24608.3154
CXB2/ByJ m 41288.2 8514.5709 58790.1512 23786.2488
CXB3/ByJ m 31295.7 10428.1771 52731.125 9860.275
CXB4/ByJ m 28878.2 10428.1771 50313.625 7442.775
CXB6/ByJ m 41558.0333 8514.5709 59059.9846 24056.0821
CXB8/HiAJ m 42550.3333 8514.5709 60052.2846 25048.3821
CXB9/HiAJ m 39887.85 10428.1771 61323.275 18452.425
DBA/2J m 29251.6667 8514.5709 46753.6179 11749.7154




  GWAS USING LINEAR MIXED MODELS