Project measure / variable:   HMDPpheno6   HV_carnitine

ID, description, units MPD:50167   HV_carnitine   liver hydroxyisovaleroyl carnitine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   104 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver hydroxyisovaleroyl carnitine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested104 strains
Mean of the strain means274211   None
Median of the strain means260404   None
SD of the strain means± 107935
Coefficient of variation (CV)0.394
Min–max range of strain means116484   –   929090   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 227131715677.627 11356585783.8814 1.7083 0.0859
Residuals 32 212727239307.254 6647726228.3517


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 260542.0 0.0   1   0.0 0.0 260542.0, 260542.0 -0.13
A/J m 313896.0 45935.0   2   32481.0 0.146 281416.0, 346377.0 0.37
AKR/J m 335080.0 0.0   1   0.0 0.0 335080.0, 335080.0 0.56
AXB10/PgnJ m 187092.0 0.0   1   0.0 0.0 187092.0, 187092.0 -0.81
AXB12/PgnJ m 250951.0 0.0   1   0.0 0.0 250951.0, 250951.0 -0.22
AXB13/PgnJ m 206157.0 0.0   1   0.0 0.0 206157.0, 206157.0 -0.63
AXB15/PgnJ m 250219.0 0.0   1   0.0 0.0 250219.0, 250219.0 -0.22
AXB19a/PgnJ m 302722.0 0.0   1   0.0 0.0 302722.0, 302722.0 0.26
AXB19b/PgnJ m 372621.0 60669.0   2   42900.0 0.163 329721.0, 415521.0 0.91
AXB19/PgnJ m 247559.0 0.0   1   0.0 0.0 247559.0, 247559.0 -0.25
AXB1/PgnJ m 551986.0 0.0   1   0.0 0.0 551986.0, 551986.0 2.57
AXB23/PgnJ m 208381.0 0.0   1   0.0 0.0 208381.0, 208381.0 -0.61
AXB24/PgnJ m 277172.0 79474.0   2   56196.0 0.287 220976.0, 333368.0 0.03
AXB2/PgnJ m 565476.0 0.0   1   0.0 0.0 565476.0, 565476.0 2.7
AXB4/PgnJ m 267541.0 0.0   1   0.0 0.0 267541.0, 267541.0 -0.06
AXB5/PgnJ m 257343.0 0.0   1   0.0 0.0 257343.0, 257343.0 -0.16
AXB6/PgnJ m 263416.0 0.0   1   0.0 0.0 263416.0, 263416.0 -0.1
AXB8/PgnJ m 261729.0 0.0   1   0.0 0.0 261729.0, 261729.0 -0.12
BALB/cJ m 232223.0 71135.0   3 41070.0 0.306 151897.0, 287253.0 -0.39
BTBR T+ Itpr3tf/J m 288496.0 0.0   1   0.0 0.0 288496.0, 288496.0 0.13
BUB/BnJ m 415434.0 0.0   1   0.0 0.0 415434.0, 415434.0 1.31
BXA11/PgnJ m 145055.0 0.0   1   0.0 0.0 145055.0, 145055.0 -1.2
BXA12/PgnJ m 253080.0 0.0   1   0.0 0.0 253080.0, 253080.0 -0.2
BXA13/PgnJ m 312426.0 0.0   1   0.0 0.0 312426.0, 312426.0 0.35
BXA14/PgnJ m 159664.0 0.0   1   0.0 0.0 159664.0, 159664.0 -1.06
BXA16/PgnJ m 319921.0 111247.0   2   78664.0 0.348 241257.0, 398585.0 0.42
BXA1/PgnJ m 210087.0 0.0   1   0.0 0.0 210087.0, 210087.0 -0.59
BXA24/PgnJ m 260265.0 0.0   1   0.0 0.0 260265.0, 260265.0 -0.13
BXA25/PgnJ m 253080.0 0.0   1   0.0 0.0 253080.0, 253080.0 -0.2
BXA26/PgnJ m 287451.0 0.0   1   0.0 0.0 287451.0, 287451.0 0.12
BXA2/PgnJ m 201922.0 0.0   1   0.0 0.0 201922.0, 201922.0 -0.67
BXA4/PgnJ m 184006.0 0.0   1   0.0 0.0 184006.0, 184006.0 -0.84
BXA7/PgnJ m 315589.0 0.0   1   0.0 0.0 315589.0, 315589.0 0.38
BXA8/PgnJ m 116484.0 0.0   1   0.0 0.0 116484.0, 116484.0 -1.46
BXD11/TyJ m 208647.0 0.0   1   0.0 0.0 208647.0, 208647.0 -0.61
BXD12/TyJ m 386843.0 0.0   1   0.0 0.0 386843.0, 386843.0 1.04
BXD13/TyJ m 193961.0 0.0   1   0.0 0.0 193961.0, 193961.0 -0.74
BXD14/TyJ m 149958.0 0.0   1   0.0 0.0 149958.0, 149958.0 -1.15
BXD15/TyJ m 162042.0 0.0   1   0.0 0.0 162042.0, 162042.0 -1.04
BXD18/TyJ m 294404.0 0.0   1   0.0 0.0 294404.0, 294404.0 0.19
BXD19/TyJ m 172840.0 16827.0   2   11899.0 0.0974 160941.0, 184738.0 -0.94
BXD1/TyJ m 342087.0 0.0   1   0.0 0.0 342087.0, 342087.0 0.63
BXD20/TyJ m 304224.0 0.0   1   0.0 0.0 304224.0, 304224.0 0.28
BXD21/TyJ m 288714.0 0.0   1   0.0 0.0 288714.0, 288714.0 0.13
BXD22/TyJ m 371717.0 0.0   1   0.0 0.0 371717.0, 371717.0 0.9
BXD24/TyJ m 230125.0 0.0   1   0.0 0.0 230125.0, 230125.0 -0.41
BXD24/TyJ-Cep290rd16/J m 180773.0 0.0   1   0.0 0.0 180773.0, 180773.0 -0.87
BXD28/TyJ m 264418.0 0.0   1   0.0 0.0 264418.0, 264418.0 -0.09
BXD29-Tlr4lps-2J/J m 189414.0 0.0   1   0.0 0.0 189414.0, 189414.0 -0.79
BXD2/TyJ m 147512.0 0.0   1   0.0 0.0 147512.0, 147512.0 -1.17
BXD32/TyJ m 281508.0 0.0   1   0.0 0.0 281508.0, 281508.0 0.07
BXD33/TyJ m 395193.0 0.0   1   0.0 0.0 395193.0, 395193.0 1.12
BXD34/TyJ m 437378.0 0.0   1   0.0 0.0 437378.0, 437378.0 1.51
BXD36/TyJ m 212790.0 0.0   1   0.0 0.0 212790.0, 212790.0 -0.57
BXD38/TyJ m 291478.0 0.0   1   0.0 0.0 291478.0, 291478.0 0.16
BXD39/TyJ m 133250.0 0.0   1   0.0 0.0 133250.0, 133250.0 -1.31
BXD40/TyJ m 308135.0 0.0   1   0.0 0.0 308135.0, 308135.0 0.31
BXD42/TyJ m 261608.0 0.0   1   0.0 0.0 261608.0, 261608.0 -0.12
BXD5/TyJ m 214799.0 0.0   1   0.0 0.0 214799.0, 214799.0 -0.55
BXD6/TyJ m 254289.0 0.0   1   0.0 0.0 254289.0, 254289.0 -0.18
BXD8/TyJ m 346316.0 0.0   1   0.0 0.0 346316.0, 346316.0 0.67
BXD9/TyJ m 147247.0 0.0   1   0.0 0.0 147247.0, 147247.0 -1.18
BXH10/TyJ m 240837.0 0.0   1   0.0 0.0 240837.0, 240837.0 -0.31
BXH19/TyJ m 255208.0 0.0   1   0.0 0.0 255208.0, 255208.0 -0.18
BXH20/KccJ m 181362.0 0.0   1   0.0 0.0 181362.0, 181362.0 -0.86
BXH22/KccJ m 223285.0 0.0   1   0.0 0.0 223285.0, 223285.0 -0.47
BXH2/TyJ m 225510.0 0.0   1   0.0 0.0 225510.0, 225510.0 -0.45
BXH4/TyJ m 232141.0 19449.0   2   13753.0 0.0838 218389.0, 245894.0 -0.39
BXH6/TyJ m 285855.0 0.0   1   0.0 0.0 285855.0, 285855.0 0.11
BXH7/TyJ m 412502.0 0.0   1   0.0 0.0 412502.0, 412502.0 1.28
BXH8/TyJ m 174887.0 0.0   1   0.0 0.0 174887.0, 174887.0 -0.92
C3H/HeJ m 276506.0 105779.0   2   74797.0 0.383 201709.0, 351303.0 0.02
C57BL/6J m 290522.0 103976.0   5 46500.0 0.358 211579.0, 472188.0 0.15
C57L/J m 375771.0 0.0   1   0.0 0.0 375771.0, 375771.0 0.94
C58/J m 477612.0 0.0   1   0.0 0.0 477612.0, 477612.0 1.88
CAST/EiJ m 268590.0 0.0   1   0.0 0.0 268590.0, 268590.0 -0.05
CBA/J m 373265.0 0.0   1   0.0 0.0 373265.0, 373265.0 0.92
CE/J m 310020.0 0.0   1   0.0 0.0 310020.0, 310020.0 0.33
CXB11/HiAJ m 197882.0 169002.0   2   119503.0 0.854 78380.0, 317385.0 -0.71
CXB12/HiAJ m 301705.0 88630.0   2   62671.0 0.294 239034.0, 364376.0 0.25
CXB13/HiAJ m 394840.0 49102.0   2   34720.0 0.124 360119.0, 429560.0 1.12
CXB1/ByJ m 313337.0 98628.0   3 56943.0 0.315 229220.0, 421883.0 0.36
CXB2/ByJ m 234815.0 11490.0   3 6634.0 0.0489 225516.0, 247661.0 -0.36
CXB3/ByJ m 196534.0 78257.0   2   55336.0 0.398 141198.0, 251870.0 -0.72
CXB4/ByJ m 140240.0 16434.0   2   11620.0 0.117 128620.0, 151860.0 -1.24
CXB6/ByJ m 272657.0 122944.0   3 70982.0 0.451 161409.0, 404656.0 -0.01
CXB7/ByJ m 149270.0 24533.0   2   17348.0 0.164 131922.0, 166618.0 -1.16
CXB8/HiAJ m 254442.0 103869.0   3 59969.0 0.408 134817.0, 321741.0 -0.18
CXB9/HiAJ m 145515.0 33012.0   3 19059.0 0.227 119814.0, 182746.0 -1.19
DBA/2J m 215158.0 34149.0   4 17074.0 0.159 184699.0, 251298.0 -0.55
FVB/NJ m 929090.0 0.0   1   0.0 0.0 929090.0, 929090.0 6.07
I/LnJ m 384043.0 0.0   1   0.0 0.0 384043.0, 384043.0 1.02
KK/HlJ m 181788.0 0.0   1   0.0 0.0 181788.0, 181788.0 -0.86
LG/J m 223254.0 0.0   1   0.0 0.0 223254.0, 223254.0 -0.47
LP/J m 384905.0 0.0   1   0.0 0.0 384905.0, 384905.0 1.03
MA/MyJ m 379920.0 0.0   1   0.0 0.0 379920.0, 379920.0 0.98
NOD/ShiLtJ m 323867.0 0.0   1   0.0 0.0 323867.0, 323867.0 0.46
NON/ShiLtJ m 357647.0 0.0   1   0.0 0.0 357647.0, 357647.0 0.77
NZW/LacJ m 232704.0 0.0   1   0.0 0.0 232704.0, 232704.0 -0.38
PL/J m 269013.0 0.0   1   0.0 0.0 269013.0, 269013.0 -0.05
RIIIS/J m 201222.0 0.0   1   0.0 0.0 201222.0, 201222.0 -0.68
SEA/GnJ m 172855.0 0.0   1   0.0 0.0 172855.0, 172855.0 -0.94
SJL/J m 318097.0 0.0   1   0.0 0.0 318097.0, 318097.0 0.41
SWR/J m 232528.0 0.0   1   0.0 0.0 232528.0, 232528.0 -0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 313896.5 57652.9541 431331.7245 196461.2755
AXB19b/PgnJ m 372620.9 57652.9541 490056.1245 255185.6755
AXB24/PgnJ m 277171.95 57652.9541 394607.1745 159736.7255
BALB/cJ m 232222.6 47073.4399 328108.0593 136337.1407
BXA16/PgnJ m 319920.9 57652.9541 437356.1245 202485.6755
BXD19/TyJ m 172839.8 57652.9541 290275.0245 55404.5755
BXH4/TyJ m 232141.4 57652.9541 349576.6245 114706.1755
C3H/HeJ m 276506.2 57652.9541 393941.4245 159070.9755
C57BL/6J m 290522.12 36462.9297 364794.6774 216249.5626
CXB11/HiAJ m 197882.3 57652.9541 315317.5245 80447.0755
CXB12/HiAJ m 301705.05 57652.9541 419140.2745 184269.8255
CXB13/HiAJ m 394839.55 57652.9541 512274.7745 277404.3255
CXB1/ByJ m 313336.6667 47073.4399 409222.126 217451.2074
CXB2/ByJ m 234815.3 47073.4399 330700.7593 138929.8407
CXB3/ByJ m 196534.05 57652.9541 313969.2745 79098.8255
CXB4/ByJ m 140240.1 57652.9541 257675.3245 22804.8755
CXB6/ByJ m 272656.8 47073.4399 368542.2593 176771.3407
CXB7/ByJ m 149270.05 57652.9541 266705.2745 31834.8255
CXB8/HiAJ m 254442.4 47073.4399 350327.8593 158556.9407
CXB9/HiAJ m 145515.3667 47073.4399 241400.826 49629.9074
DBA/2J m 215157.825 40766.7948 298197.0686 132118.5814




  GWAS USING LINEAR MIXED MODELS