Project measure / variable:   HMDPpheno6   pipecolate

ID, description, units MPD:50144   pipecolate   liver pipecolate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver pipecolate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means421317   None
Median of the strain means362752   None
SD of the strain means± 202104
Coefficient of variation (CV)0.480
Min–max range of strain means164365   –   1711729   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 1262570102236.84 60122385820.8018 2.8985 0.0028
Residuals 34 705257116263.805 20742856360.7001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 345148.0 0.0   1   0.0 0.0 345148.0, 345148.0 -0.38
A/J m 659886.0 245937.0   2   173903.0 0.373 485982.0, 833789.0 1.18
AKR/J m 251660.0 0.0   1   0.0 0.0 251660.0, 251660.0 -0.84
AXB10/PgnJ m 502761.0 0.0   1   0.0 0.0 502761.0, 502761.0 0.4
AXB12/PgnJ m 258370.0 0.0   1   0.0 0.0 258370.0, 258370.0 -0.81
AXB13/PgnJ m 374275.0 0.0   1   0.0 0.0 374275.0, 374275.0 -0.23
AXB15/PgnJ m 497022.0 0.0   1   0.0 0.0 497022.0, 497022.0 0.37
AXB19a/PgnJ m 552653.0 0.0   1   0.0 0.0 552653.0, 552653.0 0.65
AXB19b/PgnJ m 787693.0 535467.0   2   378632.0 0.68 409060.0, 1166325.0 1.81
AXB19/PgnJ m 812457.0 0.0   1   0.0 0.0 812457.0, 812457.0 1.94
AXB1/PgnJ m 869176.0 0.0   1   0.0 0.0 869176.0, 869176.0 2.22
AXB23/PgnJ m 294662.0 0.0   1   0.0 0.0 294662.0, 294662.0 -0.63
AXB24/PgnJ m 356860.0 141785.0   2   100257.0 0.397 256603.0, 457117.0 -0.32
AXB2/PgnJ m 405811.0 0.0   1   0.0 0.0 405811.0, 405811.0 -0.08
AXB4/PgnJ m 623933.0 0.0   1   0.0 0.0 623933.0, 623933.0 1.0
AXB5/PgnJ m 304829.0 0.0   1   0.0 0.0 304829.0, 304829.0 -0.58
AXB6/PgnJ m 223554.0 0.0   1   0.0 0.0 223554.0, 223554.0 -0.98
AXB8/PgnJ m 461331.0 0.0   1   0.0 0.0 461331.0, 461331.0 0.2
BALB/cJ m 180768.0 26002.0   3 15012.0 0.144 150986.0, 198952.0 -1.19
BTBR T+ Itpr3tf/J m 348300.0 0.0   1   0.0 0.0 348300.0, 348300.0 -0.36
BUB/BnJ m 698950.0 0.0   1   0.0 0.0 698950.0, 698950.0 1.37
BXA11/PgnJ m 440967.0 0.0   1   0.0 0.0 440967.0, 440967.0 0.1
BXA12/PgnJ m 293473.0 0.0   1   0.0 0.0 293473.0, 293473.0 -0.63
BXA13/PgnJ m 452024.0 0.0   1   0.0 0.0 452024.0, 452024.0 0.15
BXA14/PgnJ m 353774.0 0.0   1   0.0 0.0 353774.0, 353774.0 -0.33
BXA16/PgnJ m 431282.0 4047.0   2   2862.0 0.00938 428421.0, 434144.0 0.05
BXA1/PgnJ m 282504.0 0.0   1   0.0 0.0 282504.0, 282504.0 -0.69
BXA24/PgnJ m 646608.0 0.0   1   0.0 0.0 646608.0, 646608.0 1.11
BXA25/PgnJ m 355483.0 0.0   1   0.0 0.0 355483.0, 355483.0 -0.33
BXA26/PgnJ m 321207.0 0.0   1   0.0 0.0 321207.0, 321207.0 -0.5
BXA2/PgnJ m 282972.0 0.0   1   0.0 0.0 282972.0, 282972.0 -0.68
BXA4/PgnJ m 384924.0 0.0   1   0.0 0.0 384924.0, 384924.0 -0.18
BXA7/PgnJ m 606343.0 0.0   1   0.0 0.0 606343.0, 606343.0 0.92
BXA8/PgnJ m 661183.0 0.0   1   0.0 0.0 661183.0, 661183.0 1.19
BXD11/TyJ m 287587.0 0.0   1   0.0 0.0 287587.0, 287587.0 -0.66
BXD12/TyJ m 378151.0 0.0   1   0.0 0.0 378151.0, 378151.0 -0.21
BXD13/TyJ m 245419.0 0.0   1   0.0 0.0 245419.0, 245419.0 -0.87
BXD14/TyJ m 405419.0 0.0   1   0.0 0.0 405419.0, 405419.0 -0.08
BXD15/TyJ m 283311.0 0.0   1   0.0 0.0 283311.0, 283311.0 -0.68
BXD18/TyJ m 262593.0 0.0   1   0.0 0.0 262593.0, 262593.0 -0.79
BXD19/TyJ m 414025.0 61038.0   2   43160.0 0.147 370864.0, 457185.0 -0.04
BXD1/TyJ m 381182.0 0.0   1   0.0 0.0 381182.0, 381182.0 -0.2
BXD20/TyJ m 727928.0 0.0   1   0.0 0.0 727928.0, 727928.0 1.52
BXD21/TyJ m 353234.0 0.0   1   0.0 0.0 353234.0, 353234.0 -0.34
BXD22/TyJ m 331313.0 0.0   1   0.0 0.0 331313.0, 331313.0 -0.45
BXD24/TyJ m 387061.0 0.0   1   0.0 0.0 387061.0, 387061.0 -0.17
BXD24/TyJ-Cep290rd16/J m 449630.0 0.0   1   0.0 0.0 449630.0, 449630.0 0.14
BXD28/TyJ m 234755.0 5494.0   2   3885.0 0.0234 230870.0, 238639.0 -0.92
BXD29-Tlr4lps-2J/J m 512528.0 0.0   1   0.0 0.0 512528.0, 512528.0 0.45
BXD2/TyJ m 526120.0 0.0   1   0.0 0.0 526120.0, 526120.0 0.52
BXD32/TyJ m 269880.0 0.0   1   0.0 0.0 269880.0, 269880.0 -0.75
BXD33/TyJ m 366806.0 0.0   1   0.0 0.0 366806.0, 366806.0 -0.27
BXD34/TyJ m 317096.0 0.0   1   0.0 0.0 317096.0, 317096.0 -0.52
BXD36/TyJ m 211655.0 0.0   1   0.0 0.0 211655.0, 211655.0 -1.04
BXD38/TyJ m 806180.0 0.0   1   0.0 0.0 806180.0, 806180.0 1.9
BXD39/TyJ m 583284.0 0.0   1   0.0 0.0 583284.0, 583284.0 0.8
BXD40/TyJ m 345122.0 0.0   1   0.0 0.0 345122.0, 345122.0 -0.38
BXD42/TyJ m 488783.0 0.0   1   0.0 0.0 488783.0, 488783.0 0.33
BXD5/TyJ m 454145.0 0.0   1   0.0 0.0 454145.0, 454145.0 0.16
BXD6/TyJ m 318079.0 0.0   1   0.0 0.0 318079.0, 318079.0 -0.51
BXD8/TyJ m 297650.0 0.0   1   0.0 0.0 297650.0, 297650.0 -0.61
BXD9/TyJ m 481530.0 0.0   1   0.0 0.0 481530.0, 481530.0 0.3
BXH10/TyJ m 524014.0 0.0   1   0.0 0.0 524014.0, 524014.0 0.51
BXH19/TyJ m 598383.0 0.0   1   0.0 0.0 598383.0, 598383.0 0.88
BXH20/KccJ m 224314.0 0.0   1   0.0 0.0 224314.0, 224314.0 -0.97
BXH22/KccJ m 199352.0 0.0   1   0.0 0.0 199352.0, 199352.0 -1.1
BXH2/TyJ m 337908.0 0.0   1   0.0 0.0 337908.0, 337908.0 -0.41
BXH4/TyJ m 317402.0 70968.0   2   50182.0 0.224 267220.0, 367584.0 -0.51
BXH6/TyJ m 609968.0 0.0   1   0.0 0.0 609968.0, 609968.0 0.93
BXH7/TyJ m 340202.0 0.0   1   0.0 0.0 340202.0, 340202.0 -0.4
BXH8/TyJ m 435273.0 0.0   1   0.0 0.0 435273.0, 435273.0 0.07
BXH9/TyJ m 268264.0 0.0   1   0.0 0.0 268264.0, 268264.0 -0.76
C3H/HeJ m 442959.0 134464.0   2   95080.0 0.304 347878.0, 538039.0 0.11
C57BL/6J m 389233.0 51960.0   5 23237.0 0.133 323467.0, 445871.0 -0.16
C57L/J m 1711729.0 0.0   1   0.0 0.0 1711729.0, 1711729.0 6.38
C58/J m 821906.0 0.0   1   0.0 0.0 821906.0, 821906.0 1.98
CAST/EiJ m 497176.0 0.0   1   0.0 0.0 497176.0, 497176.0 0.38
CBA/J m 301956.0 0.0   1   0.0 0.0 301956.0, 301956.0 -0.59
CE/J m 306408.0 0.0   1   0.0 0.0 306408.0, 306408.0 -0.57
CXB11/HiAJ m 432107.0 297324.0   2   210240.0 0.688 221867.0, 642346.0 0.05
CXB12/HiAJ m 164365.0 73611.0   2   52051.0 0.448 112314.0, 216416.0 -1.27
CXB13/HiAJ m 353391.0 83627.0   3 48282.0 0.237 290092.0, 448194.0 -0.34
CXB1/ByJ m 337510.0 71848.0   3 41481.0 0.213 267991.0, 411480.0 -0.41
CXB2/ByJ m 495963.0 205876.0   3 118863.0 0.415 355767.0, 732325.0 0.37
CXB3/ByJ m 339877.0 11926.0   2   8433.0 0.0351 331444.0, 348310.0 -0.4
CXB4/ByJ m 313938.0 29772.0   2   21052.0 0.0948 292885.0, 334990.0 -0.53
CXB6/ByJ m 242876.0 46277.0   3 26718.0 0.191 191295.0, 280755.0 -0.88
CXB7/ByJ m 269220.0 5871.0   2   4151.0 0.0218 265068.0, 273371.0 -0.75
CXB8/HiAJ m 686836.0 199076.0   3 114937.0 0.29 482946.0, 880722.0 1.31
CXB9/HiAJ m 247028.0 68402.0   3 39492.0 0.277 200052.0, 325504.0 -0.86
DBA/2J m 323495.0 26052.0   4 13026.0 0.0805 290846.0, 351525.0 -0.48
FVB/NJ m 383648.0 0.0   1   0.0 0.0 383648.0, 383648.0 -0.19
I/LnJ m 456222.0 0.0   1   0.0 0.0 456222.0, 456222.0 0.17
KK/HlJ m 432569.0 0.0   1   0.0 0.0 432569.0, 432569.0 0.06
LG/J m 685234.0 0.0   1   0.0 0.0 685234.0, 685234.0 1.31
LP/J m 331426.0 0.0   1   0.0 0.0 331426.0, 331426.0 -0.44
MA/MyJ m 213425.0 0.0   1   0.0 0.0 213425.0, 213425.0 -1.03
NOD/ShiLtJ m 252619.0 0.0   1   0.0 0.0 252619.0, 252619.0 -0.83
NON/ShiLtJ m 401040.0 0.0   1   0.0 0.0 401040.0, 401040.0 -0.1
NZW/LacJ m 330575.0 0.0   1   0.0 0.0 330575.0, 330575.0 -0.45
PL/J m 358698.0 0.0   1   0.0 0.0 358698.0, 358698.0 -0.31
RIIIS/J m 291301.0 0.0   1   0.0 0.0 291301.0, 291301.0 -0.64
SEA/GnJ m 435004.0 0.0   1   0.0 0.0 435004.0, 435004.0 0.07
SJL/J m 612796.0 0.0   1   0.0 0.0 612796.0, 612796.0 0.95
SM/J m 280453.0 0.0   1   0.0 0.0 280453.0, 280453.0 -0.7
SWR/J m 218211.0 0.0   1   0.0 0.0 218211.0, 218211.0 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 659885.5 101840.2091 866849.7057 452921.2943
AXB19b/PgnJ m 787692.65 101840.2091 994656.8557 580728.4443
AXB24/PgnJ m 356859.95 101840.2091 563824.1557 149895.7443
BALB/cJ m 180768.3667 83152.1825 349753.933 11782.8004
BXA16/PgnJ m 431282.35 101840.2091 638246.5557 224318.1443
BXD19/TyJ m 414024.7 101840.2091 620988.9057 207060.4943
BXD28/TyJ m 234754.55 101840.2091 441718.7557 27790.3443
BXH4/TyJ m 317402.05 101840.2091 524366.2557 110437.8443
C3H/HeJ m 442958.65 101840.2091 649922.8557 235994.4443
C57BL/6J m 389233.08 64409.4036 520128.7368 258337.4232
CXB11/HiAJ m 432106.65 101840.2091 639070.8557 225142.4443
CXB12/HiAJ m 164365.05 101840.2091 371329.2557 0.0
CXB13/HiAJ m 353391.3333 83152.1825 522376.8996 184405.767
CXB1/ByJ m 337509.9 83152.1825 506495.4663 168524.3337
CXB2/ByJ m 495962.5667 83152.1825 664948.133 326977.0004
CXB3/ByJ m 339877.4 101840.2091 546841.6057 132913.1943
CXB4/ByJ m 313937.7 101840.2091 520901.9057 106973.4943
CXB6/ByJ m 242875.9 83152.1825 411861.4663 73890.3337
CXB7/ByJ m 269219.65 101840.2091 476183.8557 62255.4443
CXB8/HiAJ m 686835.5 83152.1825 855821.0663 517849.9337
CXB9/HiAJ m 247027.7 83152.1825 416013.2663 78042.1337
DBA/2J m 323494.95 72011.9024 469840.7433 177149.1567




  GWAS USING LINEAR MIXED MODELS