Project measure / variable:   HMDPpheno6   MMA

ID, description, units MPD:50178   MMA   liver methylmalonate (MMA) (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver methylmalonate (MMA) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means30251   None
Median of the strain means20168   None
SD of the strain means± 28100
Coefficient of variation (CV)0.929
Min–max range of strain means12026   –   166169   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 14762699362.5076 702985683.9289 5.2811 < 0.0001
Residuals 34 4525839775.0108 133112934.5591


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 31009.0 0.0   1   0.0 0.0 31009.0, 31009.0 0.03
A/J m 23180.0 1494.0   2   1056.0 0.0645 22124.0, 24237.0 -0.25
AKR/J m 18011.0 0.0   1   0.0 0.0 18011.0, 18011.0 -0.44
AXB10/PgnJ m 17584.0 0.0   1   0.0 0.0 17584.0, 17584.0 -0.45
AXB12/PgnJ m 19842.0 0.0   1   0.0 0.0 19842.0, 19842.0 -0.37
AXB13/PgnJ m 18560.0 0.0   1   0.0 0.0 18560.0, 18560.0 -0.42
AXB15/PgnJ m 22908.0 0.0   1   0.0 0.0 22908.0, 22908.0 -0.26
AXB19a/PgnJ m 21323.0 0.0   1   0.0 0.0 21323.0, 21323.0 -0.32
AXB19b/PgnJ m 20077.0 1413.0   2   999.0 0.0704 19078.0, 21076.0 -0.36
AXB19/PgnJ m 20453.0 0.0   1   0.0 0.0 20453.0, 20453.0 -0.35
AXB1/PgnJ m 14776.0 0.0   1   0.0 0.0 14776.0, 14776.0 -0.55
AXB23/PgnJ m 18998.0 0.0   1   0.0 0.0 18998.0, 18998.0 -0.4
AXB24/PgnJ m 26125.0 4124.0   2   2916.0 0.158 23209.0, 29041.0 -0.15
AXB2/PgnJ m 12109.0 0.0   1   0.0 0.0 12109.0, 12109.0 -0.65
AXB4/PgnJ m 17627.0 0.0   1   0.0 0.0 17627.0, 17627.0 -0.45
AXB5/PgnJ m 20080.0 0.0   1   0.0 0.0 20080.0, 20080.0 -0.36
AXB6/PgnJ m 19515.0 0.0   1   0.0 0.0 19515.0, 19515.0 -0.38
AXB8/PgnJ m 23338.0 0.0   1   0.0 0.0 23338.0, 23338.0 -0.25
BALB/cJ m 17821.0 2697.0   3 1557.0 0.151 15378.0, 20716.0 -0.44
BTBR T+ Itpr3tf/J m 21729.0 0.0   1   0.0 0.0 21729.0, 21729.0 -0.3
BUB/BnJ m 18651.0 0.0   1   0.0 0.0 18651.0, 18651.0 -0.41
BXA11/PgnJ m 17790.0 0.0   1   0.0 0.0 17790.0, 17790.0 -0.44
BXA12/PgnJ m 17011.0 0.0   1   0.0 0.0 17011.0, 17011.0 -0.47
BXA13/PgnJ m 18891.0 0.0   1   0.0 0.0 18891.0, 18891.0 -0.4
BXA14/PgnJ m 26374.0 0.0   1   0.0 0.0 26374.0, 26374.0 -0.14
BXA16/PgnJ m 55198.0 45824.0   2   32402.0 0.83 22796.0, 87601.0 0.89
BXA1/PgnJ m 22466.0 0.0   1   0.0 0.0 22466.0, 22466.0 -0.28
BXA24/PgnJ m 22885.0 0.0   1   0.0 0.0 22885.0, 22885.0 -0.26
BXA25/PgnJ m 16628.0 0.0   1   0.0 0.0 16628.0, 16628.0 -0.48
BXA26/PgnJ m 20256.0 0.0   1   0.0 0.0 20256.0, 20256.0 -0.36
BXA2/PgnJ m 20458.0 0.0   1   0.0 0.0 20458.0, 20458.0 -0.35
BXA4/PgnJ m 25013.0 0.0   1   0.0 0.0 25013.0, 25013.0 -0.19
BXA7/PgnJ m 17908.0 0.0   1   0.0 0.0 17908.0, 17908.0 -0.44
BXA8/PgnJ m 20021.0 0.0   1   0.0 0.0 20021.0, 20021.0 -0.36
BXD11/TyJ m 30258.0 0.0   1   0.0 0.0 30258.0, 30258.0 0.0
BXD12/TyJ m 21926.0 0.0   1   0.0 0.0 21926.0, 21926.0 -0.3
BXD13/TyJ m 17060.0 0.0   1   0.0 0.0 17060.0, 17060.0 -0.47
BXD14/TyJ m 20863.0 0.0   1   0.0 0.0 20863.0, 20863.0 -0.33
BXD15/TyJ m 37187.0 0.0   1   0.0 0.0 37187.0, 37187.0 0.25
BXD18/TyJ m 19648.0 0.0   1   0.0 0.0 19648.0, 19648.0 -0.38
BXD19/TyJ m 51621.0 39826.0   2   28161.0 0.771 23460.0, 79782.0 0.76
BXD1/TyJ m 95400.0 0.0   1   0.0 0.0 95400.0, 95400.0 2.32
BXD20/TyJ m 166169.0 0.0   1   0.0 0.0 166169.0, 166169.0 4.84
BXD21/TyJ m 67236.0 0.0   1   0.0 0.0 67236.0, 67236.0 1.32
BXD22/TyJ m 44624.0 0.0   1   0.0 0.0 44624.0, 44624.0 0.51
BXD24/TyJ m 43695.0 0.0   1   0.0 0.0 43695.0, 43695.0 0.48
BXD24/TyJ-Cep290rd16/J m 54777.0 0.0   1   0.0 0.0 54777.0, 54777.0 0.87
BXD28/TyJ m 20722.0 1527.0   2   1079.0 0.0737 19642.0, 21801.0 -0.34
BXD29-Tlr4lps-2J/J m 75033.0 0.0   1   0.0 0.0 75033.0, 75033.0 1.59
BXD2/TyJ m 24999.0 0.0   1   0.0 0.0 24999.0, 24999.0 -0.19
BXD32/TyJ m 13446.0 0.0   1   0.0 0.0 13446.0, 13446.0 -0.6
BXD33/TyJ m 90517.0 0.0   1   0.0 0.0 90517.0, 90517.0 2.14
BXD34/TyJ m 19844.0 0.0   1   0.0 0.0 19844.0, 19844.0 -0.37
BXD36/TyJ m 22045.0 0.0   1   0.0 0.0 22045.0, 22045.0 -0.29
BXD38/TyJ m 99966.0 0.0   1   0.0 0.0 99966.0, 99966.0 2.48
BXD39/TyJ m 68900.0 0.0   1   0.0 0.0 68900.0, 68900.0 1.38
BXD40/TyJ m 18175.0 0.0   1   0.0 0.0 18175.0, 18175.0 -0.43
BXD42/TyJ m 114084.0 0.0   1   0.0 0.0 114084.0, 114084.0 2.98
BXD5/TyJ m 25855.0 0.0   1   0.0 0.0 25855.0, 25855.0 -0.16
BXD6/TyJ m 19511.0 0.0   1   0.0 0.0 19511.0, 19511.0 -0.38
BXD8/TyJ m 136975.0 0.0   1   0.0 0.0 136975.0, 136975.0 3.8
BXD9/TyJ m 33085.0 0.0   1   0.0 0.0 33085.0, 33085.0 0.1
BXH10/TyJ m 16737.0 0.0   1   0.0 0.0 16737.0, 16737.0 -0.48
BXH19/TyJ m 16315.0 0.0   1   0.0 0.0 16315.0, 16315.0 -0.5
BXH20/KccJ m 24655.0 0.0   1   0.0 0.0 24655.0, 24655.0 -0.2
BXH22/KccJ m 17346.0 0.0   1   0.0 0.0 17346.0, 17346.0 -0.46
BXH2/TyJ m 14151.0 0.0   1   0.0 0.0 14151.0, 14151.0 -0.57
BXH4/TyJ m 15843.0 911.0   2   644.0 0.0575 15199.0, 16487.0 -0.51
BXH6/TyJ m 20835.0 0.0   1   0.0 0.0 20835.0, 20835.0 -0.34
BXH7/TyJ m 14814.0 0.0   1   0.0 0.0 14814.0, 14814.0 -0.55
BXH8/TyJ m 19350.0 0.0   1   0.0 0.0 19350.0, 19350.0 -0.39
BXH9/TyJ m 22458.0 0.0   1   0.0 0.0 22458.0, 22458.0 -0.28
C3H/HeJ m 17600.0 4127.0   2   2918.0 0.234 14682.0, 20518.0 -0.45
C57BL/6J m 16138.0 1798.0   5 804.0 0.111 14106.0, 18222.0 -0.5
C57L/J m 14426.0 0.0   1   0.0 0.0 14426.0, 14426.0 -0.56
C58/J m 19479.0 0.0   1   0.0 0.0 19479.0, 19479.0 -0.38
CAST/EiJ m 30770.0 0.0   1   0.0 0.0 30770.0, 30770.0 0.02
CBA/J m 18426.0 0.0   1   0.0 0.0 18426.0, 18426.0 -0.42
CE/J m 27208.0 0.0   1   0.0 0.0 27208.0, 27208.0 -0.11
CXB11/HiAJ m 17328.0 524.0   2   370.0 0.0302 16958.0, 17698.0 -0.46
CXB12/HiAJ m 17172.0 3067.0   2   2169.0 0.179 15003.0, 19340.0 -0.47
CXB13/HiAJ m 20762.0 4353.0   3 2513.0 0.21 15793.0, 23900.0 -0.34
CXB1/ByJ m 20702.0 2764.0   3 1596.0 0.134 17722.0, 23182.0 -0.34
CXB2/ByJ m 15786.0 2968.0   3 1714.0 0.188 13265.0, 19057.0 -0.51
CXB3/ByJ m 22147.0 7996.0   2   5654.0 0.361 16493.0, 27801.0 -0.29
CXB4/ByJ m 24039.0 466.0   2   330.0 0.0194 23709.0, 24369.0 -0.22
CXB6/ByJ m 20605.0 4337.0   3 2504.0 0.21 17927.0, 25609.0 -0.34
CXB7/ByJ m 20492.0 1173.0   2   829.0 0.0572 19663.0, 21321.0 -0.35
CXB8/HiAJ m 17481.0 2620.0   3 1512.0 0.15 15056.0, 20259.0 -0.45
CXB9/HiAJ m 23541.0 3528.0   3 2037.0 0.15 20880.0, 27543.0 -0.24
DBA/2J m 74378.0 13525.0   4 6762.0 0.182 66271.0, 94600.0 1.57
FVB/NJ m 17406.0 0.0   1   0.0 0.0 17406.0, 17406.0 -0.46
I/LnJ m 18204.0 0.0   1   0.0 0.0 18204.0, 18204.0 -0.43
KK/HlJ m 18136.0 0.0   1   0.0 0.0 18136.0, 18136.0 -0.43
LG/J m 17760.0 0.0   1   0.0 0.0 17760.0, 17760.0 -0.44
LP/J m 21913.0 0.0   1   0.0 0.0 21913.0, 21913.0 -0.3
MA/MyJ m 15665.0 0.0   1   0.0 0.0 15665.0, 15665.0 -0.52
NOD/ShiLtJ m 18739.0 0.0   1   0.0 0.0 18739.0, 18739.0 -0.41
NON/ShiLtJ m 17668.0 0.0   1   0.0 0.0 17668.0, 17668.0 -0.45
NZW/LacJ m 18359.0 0.0   1   0.0 0.0 18359.0, 18359.0 -0.42
PL/J m 18395.0 0.0   1   0.0 0.0 18395.0, 18395.0 -0.42
RIIIS/J m 12026.0 0.0   1   0.0 0.0 12026.0, 12026.0 -0.65
SEA/GnJ m 19363.0 0.0   1   0.0 0.0 19363.0, 19363.0 -0.39
SJL/J m 17205.0 0.0   1   0.0 0.0 17205.0, 17205.0 -0.46
SM/J m 146886.0 0.0   1   0.0 0.0 146886.0, 146886.0 4.15
SWR/J m 29677.0 0.0   1   0.0 0.0 29677.0, 29677.0 -0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 23180.45 8158.2147 39759.9371 6600.9629
AXB19b/PgnJ m 20076.55 8158.2147 36656.0371 3497.0629
AXB24/PgnJ m 26124.7 8158.2147 42704.1871 9545.2129
BALB/cJ m 17821.2667 6661.1544 31358.3612 4284.1722
BXA16/PgnJ m 55198.25 8158.2147 71777.7371 38618.7629
BXD19/TyJ m 51621.25 8158.2147 68200.7371 35041.7629
BXD28/TyJ m 20721.9 8158.2147 37301.3871 4142.4129
BXH4/TyJ m 15843.4 8158.2147 32422.8871 0.0
C3H/HeJ m 17599.8 8158.2147 34179.2871 1020.3129
C57BL/6J m 16138.2 5159.708 26623.9883 5652.4117
CXB11/HiAJ m 17328.1 8158.2147 33907.5871 748.6129
CXB12/HiAJ m 17171.55 8158.2147 33751.0371 592.0629
CXB13/HiAJ m 20762.3 6661.1544 34299.3945 7225.2055
CXB1/ByJ m 20701.8667 6661.1544 34238.9612 7164.7722
CXB2/ByJ m 15785.5333 6661.1544 29322.6278 2248.4388
CXB3/ByJ m 22146.9 8158.2147 38726.3871 5567.4129
CXB4/ByJ m 24039.05 8158.2147 40618.5371 7459.5629
CXB6/ByJ m 20605.2333 6661.1544 34142.3278 7068.1388
CXB7/ByJ m 20491.8 8158.2147 37071.2871 3912.3129
CXB8/HiAJ m 17480.5667 6661.1544 31017.6612 3943.4722
CXB9/HiAJ m 23540.7 6661.1544 37077.7945 10003.6055
DBA/2J m 74378.275 5768.7289 86101.7427 62654.8073




  GWAS USING LINEAR MIXED MODELS