MPD: Phenotype measures associated with MA:0002502

Sort/ Pick	Data set	Procedure / Protocol	Drug or Challenge	Phenotype Measure	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Beamer2:2	Beamer2	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1), normalized [ng/mL] IGF1_adj 11202	QTL population		f	16wks	N=999	2001

Berndt3:1	Berndt3	metabolite quantification	(none)	serum vitamin D concentration [ng/mL] vitamin_D 40501	inbred	18	m	11wks	N=4	2011

Brockmann1:31	Brockmann1	hormone quantification	(none)	IGF-1 level [ng/mL] igf1 21511	QTL population		both	6wks	N=201	2009

Brockmann1:34	Brockmann1	hormone quantification	(none)	IGF1 level, log10 transformed [log(ng/mL)] lg_igf1 21514	QTL population		both	6wks	N=201	2009

Cheverud1:40	Cheverud1	hormone quantification	high-fat diet	insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet	LGXSM w/par	15	both	20-30wks	N=8	2004

Cheverud1:41	Cheverud1	hormone quantification	high-fat diet	leptin (serum) [pg/mL] leptin 17841 control diet high-fat diet	LGXSM w/par	9	both	20-30wks	N=6	2004

Cheverud1:42	Cheverud1	lipid profile	high-fat diet	total cholesterol (serum CHOL) [mg/dL] CHOL 17842 control diet high-fat diet	LGXSM w/par	15	both	20-30wks	N=8	2004

Cheverud1:43	Cheverud1	lipid profile	high-fat diet	free fatty acid (serum FFA) [mg/dL] FFA 17843 control diet high-fat diet	LGXSM w/par	15	both	20-30wks	N=8	2004

Cheverud1:44	Cheverud1	lipid profile	high-fat diet	triglycerides (serum TG, 4h fast) [mg/dL] TG 17844 control diet high-fat diet	LGXSM w/par	15	both	20-30wks	N=8	2004

Cowell1:1	Cowell1	hormone quantification	Staphylococcus aureus	fold-change in serum IL-6 levels 24h post-infection compared to controls [ratio] IL6 49001	inbred	13	f	8wks	N=3	2012

Donahue1:30	Donahue1	hormone quantification	(none)	osteocalcin (serum OC) [ng/mL] osteocalcin 11530	inbred w/CC7	30	both	15-16wks	N=9	2002

Donahue1:31	Donahue1	metabolic panel	(none)	thyroxine (serum T4) [µg/dL] thyroxine 11531	inbred w/CC7	29	both	15-16wks	N=9	2002

Donahue1:32	Donahue1	hormone quantification	(none)	insulin-like growth factor 1 (adjusted serum IGF-1) [ng/mL] IGF_1 11532	inbred w/CC7	30	both	15-16wks	N=9	2002

Donahue9:2	Donahue9	metabolic panel	(none)	calcium (serum Ca) [mg/dL] calcium 41802	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:3	Donahue9	metabolic panel	(none)	chloride (serum Cl) [mmol/L] chloride 41803	B6.PWD consomic w/par	24	both	11wks	N=6	2011

Donahue9:4	Donahue9	metabolic panel	(none)	magnesium (serum Mg) [mg/dL] magnesium 41804	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:5	Donahue9	metabolic panel	(none)	phosphorus (serum P) [mg/dL] phosphorus 41805	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:6	Donahue9	metabolic panel	(none)	potassium (serum K) [mmol/L] potassium 41806	B6.PWD consomic w/par	24	both	11wks	N=6	2011

Donahue9:7	Donahue9	metabolic panel	(none)	sodium (serum Na) [mmol/L] sodium 41807	B6.PWD consomic w/par	24	both	11wks	N=6	2011

Donahue9:8	Donahue9	metabolic panel	(none)	alkaline phosphatase (serum ALP) [IU/L] ALP 41808	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:9	Donahue9	metabolic panel	(none)	alanine transaminase (serum ALT) [IU/L] ALT 41809	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:10	Donahue9	metabolic panel	(none)	aspartate transaminase (serum AST) [IU/L] AST 41810	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:11	Donahue9	metabolic panel	(none)	lipase (serum LIP) [U/L] LIP 41811	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:12	Donahue9	metabolic panel	(none)	lactate dehydrogenase (serum LDH) [U/L] LDH 41812	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:13	Donahue9	metabolic panel	(none)	dissolved-ionized carbon dioxide (serum CO₂) [mmol/L] carbon_dioxide 41813	B6.PWD consomic w/par	24	both	11wks	N=6	2011

Donahue9:14	Donahue9	metabolic panel	(none)	albumin (serum Alb) [g/dL] ALB 41814	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:15	Donahue9	metabolic panel	(none)	serum creatinine [mg/dL] creatinine 41815	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:16	Donahue9	metabolic panel	(none)	total protein (serum TP) [g/dL] TP 41816	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Donahue9:17	Donahue9	metabolic panel	(none)	blood urea nitrogen (serum BUN) [mg/dL] BUN 41817	B6.PWD consomic w/par	25	both	11wks	N=8	2011

Eumorphia7:1	Eumorphia7	immunoglobulin quantification	(none)	immunoglobulin M (serum IgM) [µg/mL] IgM 29601	inbred	6	both	9-12wks	N=5	2008

Eumorphia7:2	Eumorphia7	immunoglobulin quantification	(none)	immunoglobulin G3 (serum IgG3) [µg/mL] IgG3 29602	inbred	6	both	9-12wks	N=5	2008

Eumorphia7:3	Eumorphia7	immunoglobulin quantification	(none)	immunoglobulin G1 (serum IgG1) [µg/mL] IgG1 29603	inbred	6	both	9-12wks	N=5	2008

Eumorphia7:4	Eumorphia7	immunoglobulin quantification	(none)	immunoglobulin G2b (serum IgG2b) [µg/mL] IgG2b 29604	inbred	6	both	9-12wks	N=5	2008

Eumorphia7:5	Eumorphia7	immunoglobulin quantification	(none)	immunoglobulin G2a (serum IgG2a) [µg/mL] IgG2a 29605	inbred	6	both	9-12wks	N=5	2008

Eumorphia7:6	Eumorphia7	immunoglobulin quantification	(none)	immunoglobulin A (serum IgA) [µg/mL] IgA 29606	inbred	6	both	9-12wks	N=5	2008

Farmer1:29	Farmer1	hormone quantification	(none)	lgG2a antibodies against escherichia coli membrane antigens [ng/ml] IgG2aantiECM 11329	QTL population		both	6wks	N=206	2001

Farmer1:30	Farmer1	hormone quantification	(none)	levels of total lgG reactivity against escherichia coli membrane (ECM) antigens [ng/ml] IgGantiECM 11330	QTL population		both	6wks	N=206	2001

Farmer1:31	Farmer1	hormone quantification	(none)	secretory IgA in collected blood [ng/ml] IgA 11331	QTL population		both	6wks	N=206	2001

Gould1:5	Gould1	drug and metabolite quantification	lithium	serum lithium concentration [mmol/L] blood_lithium 37405 lithium dose [mg/kg]: 200 300 400	inbred	11	m	7-8wks	N=8	2011

Graham1:61	Graham1	immunoglobulin quantification	West Nile virus	virus-specific IgM in serum, post infection [ng/mL] WNV_IgM 63361 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Harrill1:21	Harrill1	metabolic panel	isoniazid	alanine transaminase (serum ALT) [IU/L] ALT 39521 control isoniazid	inbred	34	f	8-10wks	N=4	2011

Harrill2:11	Harrill2	metabolic panel	DB289	alanine transaminase (serum ALT) [IU/L] ALT 44111 control DB289 difference	inbred	34	f	6-8wks	N=5	2012

Harrill2:15	Harrill2	metabolic panel	DB289	blood urea nitrogen (serum BUN) [mg/dL] BUN 44115 control DB289 difference	inbred	34	f	6-8wks	N=5	2012

Harrill2:21	Harrill2	metabolic panel	DB289	creatinine (serum CREA) [mg/dL] serum_CREA 44121 control DB289 difference	inbred	34	f	6-8wks	N=5	2012

Pletcher1:5	Pletcher1	hormone quantification	(none)	serum corticosterone, log transformed [log(µg/dL)] corticosterone_log 36005	inbred	29	m	7-10wks*	N=6	2007

Pletcher1:20	Pletcher1	hormone quantification	(none)	serum corticosterone [µg/dL] corticosterone 36020	inbred	29	m	7-10wks*	N=6	2007

Richards-Smith1:9	Richards-Smith1	metabolic panel	macronutrient diet option	glucose (serum) [mg/dL] Serum-glucose 12409	QTL population		m	9-13wks	N=502	2002

Rusyn2:11	Rusyn2	metabolic panel	(none)	alanine transaminase (serum ALT), naive [IU/L] ALT 36111	inbred	16	m	7wks	N=3	2010

Rusyn2:12	Rusyn2	metabolic panel	trichloroethylene	alanine transaminase (serum ALT), control group [IU/L] ALT_ctrl 36112 time: 2h 8h 24h	inbred	16	m	7wks	N=3	2010

Rusyn2:17	Rusyn2	metabolic panel	trichloroethylene	alanine transaminase (serum ALT), treated group [IU/L] ALT_tce 36117 time: 2h 8h 24h	inbred	16	m	7wks	N=3	2010

Rusyn2:21	Rusyn2	metabolic panel	(none)	aspartate transaminase (serum AST), naive [IU/L] AST 36121	inbred	15	m	7wks	N=3	2010

Rusyn2:22	Rusyn2	metabolic panel	trichloroethylene	aspartate transaminase (serum AST), control group [IU/L] AST_ctrl 36122 time: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:27	Rusyn2	metabolic panel	trichloroethylene	aspartate transaminase (serum AST), treated group [IU/L] AST_tce 36127 time: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:31	Rusyn2	metabolic panel	(none)	blood urea nitrogen (serum BUN), naive [mg/dL] BUN 36131	inbred	15	m	7wks	N=3	2010

Rusyn2:32	Rusyn2	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), control group [mg/dL] BUN_ctrl 36132 time: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:37	Rusyn2	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), treated group [mg/dL] BUN_tce 36137 time: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:67	Rusyn2	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (serum DCA x 10^-3) [nmol/mL] DCA_tce 36167 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:75	Rusyn2	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (serum TCA) [nmol/mL] TCA_tce 36175 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:85	Rusyn2	drug and metabolite quantification	trichloroethylene	DCV cysteine (serum DCVC x 10^-3) [nmol/mL] DCV_cysteine_tce 36185 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=2	2010

Rusyn2:95	Rusyn2	drug and metabolite quantification	trichloroethylene	DCV glutathione (serum DCVG x 10^-3) [nmol/mL] DCV_glutathione_tce 36195 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=2	2010

Rusyn5:1	Rusyn5	metabolic panel	high-fat diet and ethanol	serum alanine transaminase (ALT) [IU/L] ALT 43001 high-fat only high-fat and ethanol	inbred	14	m	8-14wks	N=3	2011

Rusyn6:2	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (serum TCA) [nmol/mL] TCA_serum_tce 51202	inbred	7	m	6-7wks	N=3	2014

Rusyn6:4	Rusyn6	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (serum DCA) [nmol/mL] DCA_serum_tce 51204	inbred	7	m	6-7wks	N=3	2014

Rusyn6:6	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl) glutathione (serum DCVG) [pmol/mL] DCVG_serum_tce 51206	inbred	4	m	6-7wks	N=2	2014

Rusyn6:8	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC) [pmol/mL] DCVC_serum_tce 51208	inbred	7	m	6-7wks	N=3	2014

Rusyn6:9	Rusyn6	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN) [mg/dL] BUN 51209 control TCE	inbred	7	m	6-7wks	N=4	2014

Schoenrock1:74	Schoenrock1	hormone quantification	various diets	basal serum corticosterone [ng/mL] CORT_basal 61274 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	14	f	8-9wks	N=11	2018

Schoenrock1:78	Schoenrock1	hormone quantification	various diets	serum corticosterone after 10 min restraint stress [ng/mL] CORT_stress 61278 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	14	f	8-9wks	N=11	2018

Schoenrock1:82	Schoenrock1	hormone quantification	various diets	change in serum corticosterone (stress minus basal) [ng/mL] CORT_chg 61282 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	14	f	8-9wks	N=11	2018

Shockley1:2	Shockley1	metabolic panel	high-fat diet	blood urea nitrogen (BUN) [mg/dL] BUN 33402 control diet high-fat diet difference	inbred	10	both	10-13wks	N=4	2008

Shockley1:3	Shockley1	metabolic panel	high-fat diet	calcium (serum Ca) [mg/dL] CA 33403 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:4	Shockley1	metabolic panel	high-fat diet	glutamate dehydrogenase (GLDH) [IU/L] GLDH 33404 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:5	Shockley1	metabolic panel	high-fat diet	glucose (serum GLU, 5h fast) [mg/dL] GLU 33405 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:6	Shockley1	lipid profile	high-fat diet	total cholesterol (CHOL) [mg/dL] CHOL 33406 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:7	Shockley1	lipid profile	high-fat diet	HDL cholesterol (HDL) [mg/dL] HDL 33407 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:8	Shockley1	lipid profile	high-fat diet	nonesterified fatty acid (NEFA) [mEq/L] NEFA 33408 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:9	Shockley1	lipid profile	high-fat diet	triglycerides (TG, 5h fast) [mg/dL] TG 33409 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Shockley1:10	Shockley1	metabolic panel	high-fat diet	thyroxine (T4) [µg/dL] T4 33410 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Threadgill1:6	Threadgill1	metabolic panel	acetaminophen	alanine transaminase (serum ALT) [IU/L] ALT_ctrl 19406	inbred w/CC7	37	m	8-17wks	N=2	2005

Threadgill1:7	Threadgill1	metabolic panel	acetaminophen	alanine transaminase (serum ALT), t=4h [IU/L] ALT_Rx100_4h 19407	inbred w/CC7	7	m	8-17wks	N=4	2005

Threadgill1:8	Threadgill1	metabolic panel	acetaminophen	alanine transaminase (serum ALT), t=12h [IU/L] ALT_Rx100_12h 19408	inbred w/CC7	7	m	8-17wks	N=4	2005

Threadgill1:9	Threadgill1	metabolic panel	acetaminophen	alanine transaminase (serum ALT), t=24h [IU/L] ALT_Rx100_24h 19409	inbred w/CC7	7	m	8-17wks	N=3	2005

Threadgill1:10	Threadgill1	metabolic panel	acetaminophen	aspartate transaminase (serum AST) [IU/L] AST 19410 dose (mg/kg): control 100 200 300	inbred w/CC7	37	m	8-17wks	N=2	2005

Threadgill1:12	Threadgill1	metabolic panel	acetaminophen	blood urea nitrogen (serum BUN) [mg/dL] BUN 19412 dose (mg/kg) control 100 200 300	inbred w/CC7	36	m	8-17wks	N=2	2005

Threadgill2:2	Threadgill2	metabolic panel	acetaminophen	alanine transaminase (serum ALT) [IU/L] ALT 39602 50 mg/kg 300 mg/kg	inbred	5	m	6-8wks	N=5	2005

Threadgill2:9	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen (APAP), 50 mg/mL dose acetaminophen [µg/mL] APAP50 39609 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:16	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen [µg/mL] APAP_Sulf_50 39616 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:22	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen glucuronide (APAP-Glc), 50 mg/mL dose acetaminophen [µg/mL] APAP_Glc_50 39622 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=4	2005

Threadgill2:32	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen (APAP), 300 mg/mL dose acetaminophen [µg/mL] APAP300 39632 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:38	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen [µg/mL] APAP_Sulf_300 39638 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:39	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen glucuronide (APAP-Glc), 300 mg/mL dose acetaminophen [µg/mL] APAP_Glc_300 39639 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Wiltshire2:7	Wiltshire2	drug and metabolite quantification	fluoxetine	drug and metabolite concentration [ng/mL] fluoxetine 38007 fluoxetine norfluoxetine	inbred	30	m	10-11wks	N=11	2011

Yuan1:1	Yuan1	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) [ng/mL] IGF1 27001 6mo 12mo 18mo	inbred	33	both		N=7	2007

Yuan3:11	Yuan3	metabolic panel	(none)	alkaline phosphatase (serum ALP) [IU/L] ALP 24411 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:16	Yuan3	metabolic panel	(none)	calcium (serum Ca) [mg/dL] Ca 24416 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:21	Yuan3	metabolic panel	(none)	chloride (serum Cl) [mmol/L] Cl 24421 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:26	Yuan3	metabolic panel	(none)	iron (serum Fe) [mmol/L] Fe 24426 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:31	Yuan3	metabolic panel	(none)	magnesium (serum Mg) [mg/dL] Mg 24431 6mo 12mo 18mo	inbred	28	both		N=6	2008

Yuan3:36	Yuan3	metabolic panel	(none)	phosphorus (serum P) [mg/dL] Phos 24436 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:41	Yuan3	metabolic panel	(none)	potassium (serum K) [mmol/L] K 24441 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:46	Yuan3	metabolic panel	(none)	sodium (serum Na) [mmol/L] Na 24446 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:61	Yuan3	metabolic panel	(none)	dissolved-ionized carbon dioxide (CO₂) [mmol/L] CO2 24461 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:66	Yuan3	metabolic panel	(none)	bilirubin (serum TBIL) [µmol/L] TBIL 24466 6mo 12mo 18mo	inbred	28	both		N=7	2008

Yuan3:76	Yuan3	metabolic panel	(none)	thyroxine (serum T4) [µg/dL] T4 24476 6mo 12mo 18mo	inbred	28	both		N=7	2008

Beamer2

hormone quantification

(none)

insulin-like growth factor 1 (serum IGF-1), normalized [ng/mL] IGF1_adj 11202

QTL population

f

16wks

N=999

2001

Berndt3

metabolite quantification

(none)

serum vitamin D concentration [ng/mL] vitamin_D 40501

inbred

18

m

11wks

N=4

2011

Brockmann1

hormone quantification

(none)

IGF-1 level [ng/mL] igf1 21511

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

IGF1 level, log10 transformed [log(ng/mL)] lg_igf1 21514

QTL population

both

6wks

N=201

2009

Cheverud1

hormone quantification

high-fat diet

insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet

LGXSM w/par

15

both

20-30wks

N=8

2004

Cheverud1

hormone quantification

high-fat diet

leptin (serum) [pg/mL] leptin 17841 control diet high-fat diet

LGXSM w/par

9

both

20-30wks

N=6

2004

Cheverud1

lipid profile

high-fat diet

total cholesterol (serum CHOL) [mg/dL] CHOL 17842 control diet high-fat diet

LGXSM w/par

15

both

20-30wks

N=8

2004

Cheverud1

lipid profile

high-fat diet

free fatty acid (serum FFA) [mg/dL] FFA 17843 control diet high-fat diet

LGXSM w/par

15

both

20-30wks

N=8

2004

Cheverud1

lipid profile

high-fat diet

triglycerides (serum TG, 4h fast) [mg/dL] TG 17844 control diet high-fat diet

LGXSM w/par

15

both

20-30wks

N=8

2004

Cowell1

hormone quantification

Staphylococcus aureus

fold-change in serum IL-6 levels 24h post-infection compared to controls [ratio] IL6 49001

inbred

13

f

8wks

N=3

2012

Donahue1

hormone quantification

(none)

osteocalcin (serum OC) [ng/mL] osteocalcin 11530

inbred w/CC7

30

both

15-16wks

N=9

2002

Donahue1

metabolic panel

(none)

thyroxine (serum T4) [µg/dL] thyroxine 11531

inbred w/CC7

29

both

15-16wks

N=9

2002

Donahue1

hormone quantification

(none)

insulin-like growth factor 1 (adjusted serum IGF-1) [ng/mL] IGF_1 11532

inbred w/CC7

30

both

15-16wks

N=9

2002

Donahue9

metabolic panel

(none)

calcium (serum Ca) [mg/dL] calcium 41802

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

chloride (serum Cl) [mmol/L] chloride 41803

B6.PWD consomic w/par

24

both

11wks

N=6

2011

Donahue9

metabolic panel

(none)

magnesium (serum Mg) [mg/dL] magnesium 41804

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

phosphorus (serum P) [mg/dL] phosphorus 41805

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

potassium (serum K) [mmol/L] potassium 41806

B6.PWD consomic w/par

24

both

11wks

N=6

2011

Donahue9

metabolic panel

(none)

sodium (serum Na) [mmol/L] sodium 41807

B6.PWD consomic w/par

24

both

11wks

N=6

2011

Donahue9

metabolic panel

(none)

alkaline phosphatase (serum ALP) [IU/L] ALP 41808

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

alanine transaminase (serum ALT) [IU/L] ALT 41809

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

aspartate transaminase (serum AST) [IU/L] AST 41810

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

lipase (serum LIP) [U/L] LIP 41811

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

lactate dehydrogenase (serum LDH) [U/L] LDH 41812

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

dissolved-ionized carbon dioxide (serum CO₂) [mmol/L] carbon_dioxide 41813

B6.PWD consomic w/par

24

both

11wks

N=6

2011

Donahue9

metabolic panel

(none)

albumin (serum Alb) [g/dL] ALB 41814

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

serum creatinine [mg/dL] creatinine 41815

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

total protein (serum TP) [g/dL] TP 41816

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Donahue9

metabolic panel

(none)

blood urea nitrogen (serum BUN) [mg/dL] BUN 41817

B6.PWD consomic w/par

25

both

11wks

N=8

2011

Eumorphia7

immunoglobulin quantification

(none)

immunoglobulin M (serum IgM) [µg/mL] IgM 29601

inbred

6

both

9-12wks

N=5

2008

Eumorphia7

immunoglobulin quantification

(none)

immunoglobulin G3 (serum IgG3) [µg/mL] IgG3 29602

inbred

6

both

9-12wks

N=5

2008

Eumorphia7

immunoglobulin quantification

(none)

immunoglobulin G1 (serum IgG1) [µg/mL] IgG1 29603

inbred

6

both

9-12wks

N=5

2008

Eumorphia7

immunoglobulin quantification

(none)

immunoglobulin G2b (serum IgG2b) [µg/mL] IgG2b 29604

inbred

6

both

9-12wks

N=5

2008

Eumorphia7

immunoglobulin quantification

(none)

immunoglobulin G2a (serum IgG2a) [µg/mL] IgG2a 29605

inbred

6

both

9-12wks

N=5

2008

Eumorphia7

immunoglobulin quantification

(none)

immunoglobulin A (serum IgA) [µg/mL] IgA 29606

inbred

6

both

9-12wks

N=5

2008

Farmer1

hormone quantification

(none)

lgG2a antibodies against escherichia coli membrane antigens [ng/ml] IgG2aantiECM 11329

QTL population

both

6wks

N=206

2001

Farmer1

hormone quantification

(none)

levels of total lgG reactivity against escherichia coli membrane (ECM) antigens [ng/ml] IgGantiECM 11330

QTL population

both

6wks

N=206

2001

Farmer1

hormone quantification

(none)

secretory IgA in collected blood [ng/ml] IgA 11331

QTL population

both

6wks

N=206

2001

Gould1

drug and metabolite quantification

lithium

serum lithium concentration [mmol/L] blood_lithium 37405 lithium dose [mg/kg]: 200 300 400

inbred

11

m

7-8wks

N=8

2011

Graham1

immunoglobulin quantification

West Nile virus

virus-specific IgM in serum, post infection [ng/mL] WNV_IgM 63361 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Harrill1

metabolic panel

isoniazid

alanine transaminase (serum ALT) [IU/L] ALT 39521 control isoniazid

inbred

34

f

8-10wks

N=4

2011

Harrill2

metabolic panel

DB289

alanine transaminase (serum ALT) [IU/L] ALT 44111 control DB289 difference

inbred

34

f

6-8wks

N=5

2012

Harrill2

metabolic panel

DB289

blood urea nitrogen (serum BUN) [mg/dL] BUN 44115 control DB289 difference

inbred

34

f

6-8wks

N=5

2012

Harrill2

metabolic panel

DB289

creatinine (serum CREA) [mg/dL] serum_CREA 44121 control DB289 difference

inbred

34

f

6-8wks

N=5

2012

Pletcher1

hormone quantification

(none)

serum corticosterone, log transformed [log(µg/dL)] corticosterone_log 36005

inbred

29

m

7-10wks*

N=6

2007

Pletcher1

hormone quantification

(none)

serum corticosterone [µg/dL] corticosterone 36020

inbred

29

m

7-10wks*

N=6

2007

Richards-Smith1

metabolic panel

macronutrient diet option

glucose (serum) [mg/dL] Serum-glucose 12409

QTL population

m

9-13wks

N=502

2002

Rusyn2

metabolic panel

(none)

alanine transaminase (serum ALT), naive [IU/L] ALT 36111

inbred

16

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

alanine transaminase (serum ALT), control group [IU/L] ALT_ctrl 36112 time: 2h 8h 24h

inbred

16

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

alanine transaminase (serum ALT), treated group [IU/L] ALT_tce 36117 time: 2h 8h 24h

inbred

16

m

7wks

N=3

2010

Rusyn2

metabolic panel

(none)

aspartate transaminase (serum AST), naive [IU/L] AST 36121

inbred

15

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

aspartate transaminase (serum AST), control group [IU/L] AST_ctrl 36122 time: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

aspartate transaminase (serum AST), treated group [IU/L] AST_tce 36127 time: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

metabolic panel

(none)

blood urea nitrogen (serum BUN), naive [mg/dL] BUN 36131

inbred

15

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

blood urea nitrogen (serum BUN), control group [mg/dL] BUN_ctrl 36132 time: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

blood urea nitrogen (serum BUN), treated group [mg/dL] BUN_tce 36137 time: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

dichloroacetic acid (serum DCA x 10^-3) [nmol/mL] DCA_tce 36167 time after treatment: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

trichloroacetic acid (serum TCA) [nmol/mL] TCA_tce 36175 time after treatment: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

DCV cysteine (serum DCVC x 10^-3) [nmol/mL] DCV_cysteine_tce 36185 time after treatment: 2h 8h 24h

inbred

15

m

7wks

N=2

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

DCV glutathione (serum DCVG x 10^-3) [nmol/mL] DCV_glutathione_tce 36195 time after treatment: 2h 8h 24h

inbred

15

m

7wks

N=2

2010

Rusyn5

metabolic panel

high-fat diet and ethanol

serum alanine transaminase (ALT) [IU/L] ALT 43001 high-fat only high-fat and ethanol

inbred

14

m

8-14wks

N=3

2011

Rusyn6

drug and metabolite quantification

trichloroethylene

trichloroacetic acid (serum TCA) [nmol/mL] TCA_serum_tce 51202

inbred

7

m

6-7wks

N=3

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

dichloroacetic acid (serum DCA) [nmol/mL] DCA_serum_tce 51204

inbred

7

m

6-7wks

N=3

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

S-(1,2-dichlorovinyl) glutathione (serum DCVG) [pmol/mL] DCVG_serum_tce 51206

inbred

4

m

6-7wks

N=2

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC) [pmol/mL] DCVC_serum_tce 51208

inbred

7

m

6-7wks

N=3

2014

Rusyn6

metabolic panel

trichloroethylene

blood urea nitrogen (serum BUN) [mg/dL] BUN 51209 control TCE

inbred

7

m

6-7wks

N=4

2014

Schoenrock1

hormone quantification

various diets

basal serum corticosterone [ng/mL] CORT_basal 61274 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet

CC RIX

14

f

8-9wks

N=11

2018

Schoenrock1

hormone quantification

various diets

serum corticosterone after 10 min restraint stress [ng/mL] CORT_stress 61278 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet

CC RIX

14

f

8-9wks

N=11

2018

Schoenrock1

hormone quantification

various diets

change in serum corticosterone (stress minus basal) [ng/mL] CORT_chg 61282 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet

CC RIX

14

f

8-9wks

N=11

2018

Shockley1

metabolic panel

high-fat diet

blood urea nitrogen (BUN) [mg/dL] BUN 33402 control diet high-fat diet difference

inbred

10

both

10-13wks

N=4

2008

Shockley1

metabolic panel

high-fat diet

calcium (serum Ca) [mg/dL] CA 33403 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

metabolic panel

high-fat diet

glutamate dehydrogenase (GLDH) [IU/L] GLDH 33404 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

metabolic panel

high-fat diet

glucose (serum GLU, 5h fast) [mg/dL] GLU 33405 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

lipid profile

high-fat diet

total cholesterol (CHOL) [mg/dL] CHOL 33406 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

lipid profile

high-fat diet

HDL cholesterol (HDL) [mg/dL] HDL 33407 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

lipid profile

high-fat diet

nonesterified fatty acid (NEFA) [mEq/L] NEFA 33408 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

lipid profile

high-fat diet

triglycerides (TG, 5h fast) [mg/dL] TG 33409 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Shockley1

metabolic panel

high-fat diet

thyroxine (T4) [µg/dL] T4 33410 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Threadgill1

metabolic panel

acetaminophen

alanine transaminase (serum ALT) [IU/L] ALT_ctrl 19406

inbred w/CC7

37

m

8-17wks

N=2

2005

Threadgill1

metabolic panel

acetaminophen

alanine transaminase (serum ALT), t=4h [IU/L] ALT_Rx100_4h 19407

inbred w/CC7

7

m

8-17wks

N=4

2005

Threadgill1

metabolic panel

acetaminophen

alanine transaminase (serum ALT), t=12h [IU/L] ALT_Rx100_12h 19408

inbred w/CC7

7

m

8-17wks

N=4

2005

Threadgill1

metabolic panel

acetaminophen

alanine transaminase (serum ALT), t=24h [IU/L] ALT_Rx100_24h 19409

inbred w/CC7

7

m

8-17wks

N=3

2005

Threadgill1

metabolic panel

acetaminophen

aspartate transaminase (serum AST) [IU/L] AST 19410 dose (mg/kg): control 100 200 300

inbred w/CC7

37

m

8-17wks

N=2

2005

Threadgill1

metabolic panel

acetaminophen

blood urea nitrogen (serum BUN) [mg/dL] BUN 19412 dose (mg/kg) control 100 200 300

inbred w/CC7

36

m

8-17wks

N=2

2005

Threadgill2

metabolic panel

acetaminophen

alanine transaminase (serum ALT) [IU/L] ALT 39602 50 mg/kg 300 mg/kg

inbred

5

m

6-8wks

N=5

2005

Threadgill2

drug and metabolite quantification

acetaminophen

serum acetaminophen (APAP), 50 mg/mL dose acetaminophen [µg/mL] APAP50 39609 baseline 0.5h 1h 2h 3h 6h

inbred

5

m

6-8wks

N=5

2005

Threadgill2

drug and metabolite quantification

acetaminophen

serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen [µg/mL] APAP_Sulf_50 39616 baseline 0.5h 1h 2h 3h 6h

inbred

5

m

6-8wks

N=5

2005

Threadgill2

drug and metabolite quantification

acetaminophen

serum acetaminophen glucuronide (APAP-Glc), 50 mg/mL dose acetaminophen [µg/mL] APAP_Glc_50 39622 baseline 0.5h 1h 2h 3h 6h

inbred

5

m

6-8wks

N=4

2005

Threadgill2

drug and metabolite quantification

acetaminophen

serum acetaminophen (APAP), 300 mg/mL dose acetaminophen [µg/mL] APAP300 39632 baseline 0.5h 1h 2h 3h 6h

inbred

5

m

6-8wks

N=5

2005

Threadgill2

drug and metabolite quantification

acetaminophen

serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen [µg/mL] APAP_Sulf_300 39638 baseline 0.5h 1h 2h 3h 6h

inbred

5

m

6-8wks

N=5

2005

Threadgill2

drug and metabolite quantification

acetaminophen

serum acetaminophen glucuronide (APAP-Glc), 300 mg/mL dose acetaminophen [µg/mL] APAP_Glc_300 39639 baseline 0.5h 1h 2h 3h 6h

inbred

5

m

6-8wks

N=5

2005

Wiltshire2

drug and metabolite quantification

fluoxetine

drug and metabolite concentration [ng/mL] fluoxetine 38007 fluoxetine norfluoxetine

inbred

30

m

10-11wks

N=11

2011

Yuan1

hormone quantification

(none)

insulin-like growth factor 1 (serum IGF-1) [ng/mL] IGF1 27001 6mo 12mo 18mo

inbred

33

both

N=7

2007

Yuan3

metabolic panel

(none)

alkaline phosphatase (serum ALP) [IU/L] ALP 24411 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

calcium (serum Ca) [mg/dL] Ca 24416 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

chloride (serum Cl) [mmol/L] Cl 24421 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

iron (serum Fe) [mmol/L] Fe 24426 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

magnesium (serum Mg) [mg/dL] Mg 24431 6mo 12mo 18mo

inbred

28

both

N=6

2008

Yuan3

metabolic panel

(none)

phosphorus (serum P) [mg/dL] Phos 24436 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

potassium (serum K) [mmol/L] K 24441 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

sodium (serum Na) [mmol/L] Na 24446 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

dissolved-ionized carbon dioxide (CO₂) [mmol/L] CO2 24461 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

bilirubin (serum TBIL) [µmol/L] TBIL 24466 6mo 12mo 18mo

inbred

28

both

N=7

2008

Yuan3

metabolic panel

(none)

thyroxine (serum T4) [µg/dL] T4 24476 6mo 12mo 18mo

inbred

28

both

N=7

2008

Phenotype measures associated with MA:0002502 'serum'

Phenotype measures associated with
MA:0002502 'serum'