Project measure / variable:   Donahue9   LIP

ID, description, units MPD:41811   LIP   lipase (serum LIP)   [U/L]  
Data set, strains Donahue9   B6.PWD consomic w/par   25 strains     sex: both     age: 11wks
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  STRAIN COMPARISON PLOT
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Donahue9 - lipase (serum LIP)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains25 strains
Mean of the strain means40.0   U/L 46.2   U/L
Median of the strain means40.8   U/L 46.7   U/L
SD of the strain means± 7.98 ± 9.17
Coefficient of variation (CV)0.200 0.199
Min–max range of strain means13.9   –   52.0   U/L 25.0   –   62.5   U/L
Mean sample size per strain8.1   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4325.2187 4325.2187 37.8144 < 0.0001
strain 22 24297.4243 1104.4284 9.6558 < 0.0001
sex:strain 22 3560.0312 161.8196 1.4148 0.1039
Residuals 329 37631.0591 114.3801


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 37.8 4.95   8 1.75 0.131 33.0, 48.0 -0.27
B6.PWD-Chr1 m 46.1 9.75   8 3.45 0.211 36.0, 68.0 -0.01
B6.PWD-Chr10.1 f 44.8 6.49   6 2.65 0.145 35.0, 54.0 0.61
B6.PWD-Chr10.1 m 61.9 21.3   8 7.52 0.344 30.0, 101.0 1.72
B6.PWD-Chr10.2 f 39.5 3.34   10 1.06 0.0846 34.0, 46.0 -0.06
B6.PWD-Chr10.2 m 43.2 8.47   10 2.68 0.196 30.0, 54.0 -0.32
B6.PWD-Chr10.3 f 40.8 9.89   6 4.04 0.242 34.0, 60.0 0.11
B6.PWD-Chr10.3 m 37.9 2.75   8 0.972 0.0726 35.0, 43.0 -0.9
B6.PWD-Chr11.1 f 46.7 6.75   12 1.95 0.145 37.0, 59.0 0.84
B6.PWD-Chr11.1 m 62.5 7.51   12 2.17 0.12 50.0, 72.0 1.78
B6.PWD-Chr11.2 f 52.0 27.1   10 8.56 0.521 24.0, 124.0 1.51
B6.PWD-Chr11.2 m 57.6 16.6   10 5.25 0.288 46.0, 100.0 1.25
B6.PWD-Chr11.3 f 41.1 3.21   10 1.02 0.0782 37.0, 48.0 0.14
B6.PWD-Chr11.3 m 48.8 10.2   8 3.6 0.209 39.0, 69.0 0.29
B6.PWD-Chr12 f 45.6 6.19   8 2.19 0.136 36.0, 55.0 0.71
B6.PWD-Chr12 m 46.9 5.33   8 1.88 0.114 41.0, 53.0 0.08
B6.PWD-Chr14 f 43.7 4.09   9 1.36 0.0937 38.0, 52.0 0.47
B6.PWD-Chr14 m 51.9 14.1   9 4.7 0.272 39.0, 87.0 0.63
B6.PWD-Chr15 f 37.4 5.6   8 1.98 0.15 25.0, 43.0 -0.32
B6.PWD-Chr15 m 45.5 4.47   8 1.58 0.0983 38.0, 51.0 -0.07
B6.PWD-Chr16 f 39.8 7.25   10 2.29 0.182 33.0, 57.0 -0.02
B6.PWD-Chr16 m 37.0 6.87   6 2.8 0.186 30.0, 48.0 -1.0
B6.PWD-Chr17 f 47.6 6.7   8 2.37 0.141 42.0, 63.0 0.96
B6.PWD-Chr17 m 49.8 6.3   8 2.23 0.127 42.0, 60.0 0.4
B6.PWD-Chr18 f 38.1 4.22   8 1.49 0.111 33.0, 44.0 -0.23
B6.PWD-Chr18 m 44.0 2.27   8 0.802 0.0515 40.0, 46.0 -0.24
B6.PWD-Chr19 f 30.4 4.84   8 1.71 0.159 25.0, 38.0 -1.2
B6.PWD-Chr19 m 32.4 2.33   8 0.822 0.0718 29.0, 36.0 -1.5
B6.PWD-Chr3 m 34.1 5.78   9 1.93 0.169 21.0, 41.0 -1.32
B6.PWD-Chr5 f 38.1 5.62   8 1.99 0.147 31.0, 47.0 -0.23
B6.PWD-Chr5 m 40.9 1.55   8 0.549 0.038 38.0, 43.0 -0.57
B6.PWD-Chr6 f 40.6 4.72   8 1.67 0.116 38.0, 52.0 0.08
B6.PWD-Chr6 m 49.4 12.4   8 4.37 0.25 35.0, 69.0 0.35
B6.PWD-Chr9 f 42.5 9.11   4 4.56 0.214 36.0, 56.0 0.32
B6.PWD-Chr9 m 46.7 12.8   7 4.84 0.274 34.0, 67.0 0.06
B6.PWD-ChrX.1 f 44.6 7.3   5 3.26 0.164 37.0, 52.0 0.58
B6.PWD-ChrX.1 m 54.3 36.2   6 14.8 0.666 37.0, 128.0 0.89
B6.PWD-ChrX.2 m 50.0 7.04   9 2.35 0.141 39.0, 60.0 0.42
B6.PWD-ChrX.3 f 43.9 4.94   8 1.75 0.113 38.0, 51.0 0.49
B6.PWD-ChrX.3 m 45.6 7.13   8 2.52 0.156 38.0, 57.0 -0.06
B6.PWD-ChrY f 34.5 1.93   8 0.681 0.0559 32.0, 37.0 -0.68
B6.PWD-ChrY m 35.0 3.3   8 1.16 0.0941 31.0, 41.0 -1.22
B6.PWD-mt f 48.1 5.69   8 2.01 0.118 38.0, 55.0 1.02
B6.PWD-mt m 55.9 11.1   8 3.91 0.198 44.0, 73.0 1.06
C57BL/6J f 27.6 4.03   8 1.43 0.146 23.0, 36.0 -1.55
C57BL/6J m 51.6 26.4   8 9.34 0.512 29.0, 112.0 0.59
PWD/PhJ f 13.9 3.48   8 1.23 0.251 10.0, 20.0 -3.26
PWD/PhJ m 25.0 9.0   9 3.0 0.36 14.0, 39.0 -2.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 37.75 3.7812 45.1884 30.3116
B6.PWD-Chr1 m 46.125 3.7812 53.5634 38.6866
B6.PWD-Chr10.1 f 44.8333 4.3662 53.4224 36.2442
B6.PWD-Chr10.1 m 61.875 3.7812 69.3134 54.4366
B6.PWD-Chr10.2 f 39.5 3.382 46.1531 32.8469
B6.PWD-Chr10.2 m 43.2 3.382 49.8531 36.5469
B6.PWD-Chr10.3 f 40.8333 4.3662 49.4224 32.2442
B6.PWD-Chr10.3 m 37.875 3.7812 45.3134 30.4366
B6.PWD-Chr11.1 f 46.6667 3.0873 52.7401 40.5932
B6.PWD-Chr11.1 m 62.5 3.0873 68.5734 56.4266
B6.PWD-Chr11.2 f 52.0 3.382 58.6531 45.3469
B6.PWD-Chr11.2 m 57.6 3.382 64.2531 50.9469
B6.PWD-Chr11.3 f 41.1 3.382 47.7531 34.4469
B6.PWD-Chr11.3 m 48.75 3.7812 56.1884 41.3116
B6.PWD-Chr12 f 45.625 3.7812 53.0634 38.1866
B6.PWD-Chr12 m 46.875 3.7812 54.3134 39.4366
B6.PWD-Chr14 f 43.6667 3.565 50.6796 36.6537
B6.PWD-Chr14 m 51.8889 3.565 58.9019 44.8759
B6.PWD-Chr15 f 37.375 3.7812 44.8134 29.9366
B6.PWD-Chr15 m 45.5 3.7812 52.9384 38.0616
B6.PWD-Chr16 f 39.8 3.382 46.4531 33.1469
B6.PWD-Chr16 m 37.0 4.3662 45.5891 28.4109
B6.PWD-Chr17 f 47.625 3.7812 55.0634 40.1866
B6.PWD-Chr17 m 49.75 3.7812 57.1884 42.3116
B6.PWD-Chr18 f 38.125 3.7812 45.5634 30.6866
B6.PWD-Chr18 m 44.0 3.7812 51.4384 36.5616
B6.PWD-Chr19 f 30.375 3.7812 37.8134 22.9366
B6.PWD-Chr19 m 32.375 3.7812 39.8134 24.9366
B6.PWD-Chr5 f 38.125 3.7812 45.5634 30.6866
B6.PWD-Chr5 m 40.875 3.7812 48.3134 33.4366
B6.PWD-Chr6 f 40.625 3.7812 48.0634 33.1866
B6.PWD-Chr6 m 49.375 3.7812 56.8134 41.9366
B6.PWD-Chr9 f 42.5 5.3474 53.0195 31.9805
B6.PWD-Chr9 m 46.7143 4.0423 54.6663 38.7623
B6.PWD-ChrX.1 f 44.6 4.7829 54.0089 35.1911
B6.PWD-ChrX.1 m 54.3333 4.3662 62.9224 45.7442
B6.PWD-ChrX.3 f 43.875 3.7812 51.3134 36.4366
B6.PWD-ChrX.3 m 45.625 3.7812 53.0634 38.1866
B6.PWD-ChrY f 34.5 3.7812 41.9384 27.0616
B6.PWD-ChrY m 35.0 3.7812 42.4384 27.5616
B6.PWD-mt f 48.125 3.7812 55.5634 40.6866
B6.PWD-mt m 55.875 3.7812 63.3134 48.4366
C57BL/6J f 27.625 3.7812 35.0634 20.1866
C57BL/6J m 51.625 3.7812 59.0634 44.1866
PWD/PhJ f 13.875 3.7812 21.3134 6.4366
PWD/PhJ m 25.0 3.565 32.013 17.987


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 41.9375 2.6737 47.1972 36.6778
B6.PWD-Chr10.1 both 53.3542 2.8879 59.0353 47.673
B6.PWD-Chr10.2 both 41.35 2.3914 46.0545 36.6455
B6.PWD-Chr10.3 both 39.3542 2.8879 45.0353 33.673
B6.PWD-Chr11.1 both 54.5833 2.1831 58.8779 50.2888
B6.PWD-Chr11.2 both 54.8 2.3914 59.5045 50.0955
B6.PWD-Chr11.3 both 44.925 2.5365 49.9148 39.9352
B6.PWD-Chr12 both 46.25 2.6737 51.5097 40.9903
B6.PWD-Chr14 both 47.7778 2.5208 52.7367 42.8189
B6.PWD-Chr15 both 41.4375 2.6737 46.6972 36.1778
B6.PWD-Chr16 both 38.4 2.7614 43.8322 32.9678
B6.PWD-Chr17 both 48.6875 2.6737 53.9472 43.4278
B6.PWD-Chr18 both 41.0625 2.6737 46.3222 35.8028
B6.PWD-Chr19 both 31.375 2.6737 36.6347 26.1153
B6.PWD-Chr5 both 39.5 2.6737 44.7597 34.2403
B6.PWD-Chr6 both 45.0 2.6737 50.2597 39.7403
B6.PWD-Chr9 both 44.6071 3.3517 51.2006 38.0137
B6.PWD-ChrX.1 both 49.4667 3.238 55.8365 43.0968
B6.PWD-ChrX.3 both 44.75 2.6737 50.0097 39.4903
B6.PWD-ChrY both 34.75 2.6737 40.0097 29.4903
B6.PWD-mt both 52.0 2.6737 57.2597 46.7403
C57BL/6J both 39.625 2.6737 44.8847 34.3653
PWD/PhJ both 19.4375 2.5984 24.549 14.326




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA