Project measure / variable:   Rusyn6   DCA_serum_tce

ID, description, units MPD:51204   DCA_serum_tce   dichloroacetic acid (serum DCA)   [nmol/mL]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - dichloroacetic acid (serum DCA)

NOD/ShiLtJC57BL/6JCAST/EiJBTBR T<+> Itpr3<tf>/JA/J129S1/SvImJNZW/LacJ nmol/mL 0.000.050.100.150.200.250.300.350.40femalemale


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means0.188   nmol/mL
Median of the strain means0.200   nmol/mL
SD of the strain means± 0.0926
Coefficient of variation (CV)0.492
Min–max range of strain means0.0667   –   0.333   nmol/mL
Mean sample size per strain2.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 5 0.1444 0.0289 4.8878 0.0134
Residuals 11 0.065 0.0059


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129S1/SvImJ m 0.1 0.0   2   0.0 0.0 0.1, 0.1 -0.95
A/J m 0.15 0.0707   2   0.05 0.471 0.1, 0.2 -0.41
BTBR T+ Itpr3tf/J m 0.2 0.0816   4 0.0408 0.408 0.1, 0.3 0.13
C57BL/6J m 0.267 0.115   3 0.0667 0.433 0.2, 0.4 0.85
CAST/EiJ m 0.2 0.0   1   0.0 0.0 0.2, 0.2 0.13
NOD/ShiLtJ m 0.333 0.0577   3 0.0333 0.173 0.3, 0.4 1.56
NZW/LacJ m 0.0667 0.0577   3 0.0333 0.866 -1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.1 0.0544 0.2196 0.0
A/J m 0.15 0.0544 0.2696 0.0304
BTBR T+ Itpr3tf/J m 0.2 0.0384 0.2846 0.1154
C57BL/6J m 0.2667 0.0444 0.3643 0.169
NOD/ShiLtJ m 0.3333 0.0444 0.431 0.2357
NZW/LacJ m 0.0667 0.0444 0.1643 0.0




  GWAS USING LINEAR MIXED MODELS

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