MPD: Project measures / variables set: Shockley1 CHOL

Project measures / variables set: Shockley1 CHOL

ID, description, units	MPD:33406 CHOL total cholesterol (CHOL) [mg/dL] high-fat diet study
Measures	• control diet • high-fat diet • difference
Data set, strains	Shockley1 inbred 10 strains sex: both age: 10-13wks
Procedure	lipid profile
Comparison	control group vs. treated group
Ontology mappings	VT:0000180 blood cholesterol amount MA:0002502 serum MP:0000180 abnormal circulating cholesterol level

Values Means Δ Means Z-scores

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Shockley1 - total cholesterol (CHOL)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	631602.3903	631602.3903	1109.5368	< 0.0001
sex	1	11313.6578	11313.6578	19.8747	< 0.0001
strain	9	286352.7326	31816.9703	55.8929	< 0.0001
group:sex	1	6680.686	6680.686	11.736	0.0008
group:strain	9	54927.9028	6103.1003	10.7213	< 0.0001
sex:strain	9	30672.0379	3408.0042	5.9868	< 0.0001
group:sex:strain	9	20403.5373	2267.0597	3.9825	0.0001
Residuals	152	86525.8	569.2487

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Shockley1	33406	lipid profile	high-fat diet	total cholesterol (CHOL) [mg/dL] control diet CHOL	inbred	10	both	10-13wks
Shockley1	33436	lipid profile	high-fat diet	total cholesterol (CHOL) [mg/dL] high-fat diet CHOL_fat	inbred	10	both	10-13wks
Shockley1	33856	lipid profile	high-fat diet	total cholesterol (CHOL) [mg/dL] difference CHOL_diff	inbred	10	both	10-13wks	(supplemental / summary measure)