Project measure / variable:   Threadgill1   ALT_Rx100_12h

ID, description, units MPD:19408   ALT_Rx100_12h   alanine transaminase (serum ALT), t=12h   [IU/L]  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   7 strains     sex: m     age: 8-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Threadgill1 - alanine transaminase (serum ALT), t=12h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means60.7   IU/L
Median of the strain means67.5   IU/L
SD of the strain means± 31.0
Coefficient of variation (CV)0.511
Min–max range of strain means12.2   –   96.3   IU/L
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 21469.5733 3578.2622 8.4275 0.0002
Residuals 18 7642.6667 424.5926


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6C3F1/J m 31.2 17.2   4 8.62 0.551 14.0, 54.0 -0.95
C3H/HeJ m 67.5 9.57   4 4.79 0.142 60.0, 80.0 0.22
C57BL/10J m 93.8 32.8   4 16.4 0.349 55.0, 135.0 1.07
CBA/J m 70.0 14.1   2   10.0 0.202 60.0, 80.0 0.3
DBA/2J m 12.2 6.99   4 3.5 0.571 4.0, 19.0 -1.56
LP/J m 96.3 32.1   3 18.6 0.334 73.0, 133.0 1.15
NOD/ShiLtJ m 53.8 16.8   4 8.39 0.312 42.0, 78.0 -0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6C3F1/J m 31.25 10.3028 52.8954 9.6046
C3H/HeJ m 67.5 10.3028 89.1454 45.8546
C57BL/10J m 93.75 10.3028 115.3954 72.1046
CBA/J m 70.0 14.5704 100.6113 39.3887
DBA/2J m 12.25 10.3028 33.8954 0.0
LP/J m 96.3333 11.8967 121.3273 71.3393
NOD/ShiLtJ m 53.75 10.3028 75.3954 32.1046




  GWAS USING LINEAR MIXED MODELS