Phenotype measures set:   Gould1   blood_lithium

ID, description, units MPD:37405   blood_lithium   serum lithium concentration   [mmol/L]
lithium study
Measures • lithium dose [mg/kg]:    • 200    • 300    • 400
Data set, strains Gould1   inbred   11 strains     sex: m     age: 7-8wks
Procedure drug and metabolite quantification
Comparisoncontrol group vs. multiple treatment / dosage groups
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
Values
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  OVERLAPPING STRAIN CURVES
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Gould1 - serum lithium concentration





  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 2 58.9232 29.4616 451.243 < 0.0001
strain 10 15.9424 1.5942 24.4178 < 0.0001
dose:strain 20 4.8945 0.2447 3.7483 < 0.0001
Residuals 216 14.1026 0.0653

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelStrains
tested
SexAge
Gould1 37405 drug and metabolite quantification lithium serum lithium concentration   [mmol/L]   dose 200 mg/kg   blood_lithium200 inbred 11 m 7-8wks
Gould1 37406 drug and metabolite quantification lithium serum lithium concentration   [mmol/L]   dose 300 mg/kg   blood_lithium300 inbred 11 m 7-8wks
Gould1 37407 drug and metabolite quantification lithium serum lithium concentration   [mmol/L]   dose 400 mg/kg   blood_lithium400 inbred 11 m 7-8wks