Phenotype measures set

ID, description, units MPD:39602   alanine transaminase (serum ALT)   [IU/L]
acetaminophen study
Measures • 50 mg/kg    • 300 mg/kg
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure metabolic panel
Comparisonmultiple dosage cohorts but no control group
Ontology mappings



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Threadgill2 - alanine transaminase (serum ALT)

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 1 104896680.348 104896680.348 120.8467 < 0.0001
strain 4 803819.893 200954.9732 0.2315 0.9189
dose:strain 4 762715.8787 190678.9697 0.2197 0.9257
Residuals 36 31248520.75 868014.4653

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Threadgill2 39602 metabolic panel acetaminophen alanine transaminase (serum ALT)   [IU/L]   dose: 50 mg/kg   ALT_Rx50 inbred 5 m 6-8wks
Threadgill2 39628 metabolic panel acetaminophen alanine transaminase (serum ALT)   [IU/L]   dose: 300 mg/kg   ALT_Rx300 inbred 5 m 6-8wks