MPD: Data set: Yuan3

Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R. Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics. 2011 Mar 16;43(5):265-70. Epub 2010 Dec 21. PubMed 21177381

Procedures conducted:

• metabolic panel		Clinical blood chemistry. Aging study, 6mo, 12mo, 18mo.
• lipid profile		Cholesterol (HDL). Aging study, 6mo, 12mo, 18mo. 4h fast, plasma.

Yuan3 downloads
• Download Yuan3 project data set animal data, as uploaded
• Download Yuan3 animal data matrix with factor-related expansion applied as necessary
• Download Yuan3 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Yuan3 measures:

Investigators	Rong Yuan The Jackson Laboratory, Bar Harbor, ME Ron Korstanje The Jackson Laboratory, Bar Harbor, ME
Participants	Tsaih SW, Schultz D, Godfrey D
Contact	Rong Yuan rong.yuan@jax.org Lab web site
Affiliated Center	JAX Nathan Shock Aging Center
Acknowledgements	Funding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type	Phenotype strain survey data set
MPD identifiers	Yuan3 MPD:244
Data changelog	3 updates/corrections. Initial release date: 08/2008.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Sample Size (Avg)
Yuan3:1	Yuan3	metabolic panel	(none)	alanine transaminase (plasma ALT) [IU/L] ALT 24401 6mo 12mo 18mo	inbred	32	both	N=6

Yuan3:6	Yuan3	metabolic panel	(none)	lipase (plasma LIP) [U/L] LIP 24406 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:11	Yuan3	metabolic panel	(none)	alkaline phosphatase (serum ALP) [IU/L] ALP 24411 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:16	Yuan3	metabolic panel	(none)	calcium (serum Ca) [mg/dL] Ca 24416 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:21	Yuan3	metabolic panel	(none)	chloride (serum Cl) [mmol/L] Cl 24421 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:26	Yuan3	metabolic panel	(none)	iron (serum Fe) [mmol/L] Fe 24426 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:31	Yuan3	metabolic panel	(none)	magnesium (serum Mg) [mg/dL] Mg 24431 6mo 12mo 18mo	inbred	32	both	N=6

Yuan3:36	Yuan3	metabolic panel	(none)	phosphorus (serum P) [mg/dL] Phos 24436 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:41	Yuan3	metabolic panel	(none)	potassium (serum K) [mmol/L] K 24441 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:46	Yuan3	metabolic panel	(none)	sodium (serum Na) [mmol/L] Na 24446 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:51	Yuan3	metabolic panel	(none)	albumin (plasma Alb) [g/dL] ALB 24451 6mo 12mo 18mo	inbred	32	both	N=6

Yuan3:56	Yuan3	metabolic panel	(none)	total protein (plasma TP) [g/dL] TP 24456 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:61	Yuan3	metabolic panel	(none)	dissolved-ionized carbon dioxide (CO₂) [mmol/L] CO2 24461 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:66	Yuan3	metabolic panel	(none)	bilirubin (serum TBIL) [µmol/L] TBIL 24466 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:71	Yuan3	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 24471 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:76	Yuan3	metabolic panel	(none)	thyroxine (serum T4) [µg/dL] T4 24476 6mo 12mo 18mo	inbred	32	both	N=7

Yuan3:81	Yuan3	metabolic panel	(none)	blood urea nitrogen (plasma BUN) [mg/dL] BUN 24481 6mo 12mo 18mo	inbred	32	both	N=6

Yuan3: Aging study: Blood chemistry for 32 inbred strains of mice (2008)