Yuan3: Aging study: Blood chemistry for 32 inbred strains of mice (2008)

Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R. Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics. 2011 Mar 16;43(5):265-70. Epub 2010 Dec 21.   PubMed 21177381  


         
Yuan3 downloads
• Download Yuan3 project data set     one row per animal, one column per trait
• Download Yuan3 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to Yuan3 measures:
    MA:0002501   plasma
    MA:0002502   serum
    MP:0000184   abnormal circulating HDL cholesterol level
    MP:0000199   abnormal circulating serum albumin level
    MP:0000202   abnormal circulating alkaline phosphatase level
    MP:0001562   abnormal circulating calcium level
    MP:0001565   abnormal circulating phosphate level
    MP:0001569   abnormal circulating bilirubin level
    MP:0001573   abnormal circulating alanine transaminase level
    MP:0001771   abnormal circulating magnesium level
    MP:0001776   abnormal circulating sodium level
    MP:0002668   abnormal circulating potassium level
    MP:0003018   abnormal circulating chloride level
    MP:0003860   abnormal carbon dioxide level
    MP:0004152   abnormal circulating iron level
    MP:0005265   abnormal blood urea nitrogen level
    MP:0005475   abnormal circulating thyroxine level
    MP:0011577   abnormal lipoprotein lipase activity
    MP:0011888   abnormal circulating total protein level
    VT:0000184   blood HDL cholesterol amount
    VT:0000199   blood albumin amount
    VT:0000202   blood alkaline phosphatase amount
    VT:0001562   blood calcium amount
    VT:0001565   blood phosphate amount
    VT:0001569   blood bilirubin amount
    VT:0001573   blood alanine transaminase amount
    VT:0001771   blood magnesium amount
    VT:0001776   blood sodium amount
    VT:0002329   blood gas amount
    VT:0002668   blood potassium amount
    VT:0003018   blood chloride amount
    VT:0004152   blood iron amount
    VT:0005265   blood urea nitrogen amount
    VT:0005475   blood thyroxine amount
    VT:0005567   blood total protein amount
    VT:0010478   blood lipase amount
Participants Rong Yuan       The Jackson Laboratory,  Bar Harbor, ME
Ron Korstanje       The Jackson Laboratory,  Bar Harbor, ME
With: Tsaih SW, Schultz D, Godfrey D
ContactRong Yuan     rong.yuan@jax.org     Lab web site
AffiliationJAX Nathan Shock Aging Center
AcknowledgementsFunding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type Phenotype strain survey data set
MPD identifiersYuan3     MPD:244
Data changelog 3 updates/corrections.       Initial release date: 08/2008.
Formatted citation
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Summary of procedures that were conducted
• metabolic panel Clinical blood chemistry. Aging study, 6mo, 12mo, 18mo.
• lipid profile Cholesterol (HDL). Aging study, 6mo, 12mo, 18mo. 4h fast, plasma.
Mice: inbred   32 strains   ♀♂   age 26, 52, 78 wks   1 cohort