Yuan3: Aging study: Blood chemistry for 32 inbred strains of mice (2008)

Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R. Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics. 2011 Mar 16;43(5):265-70. Epub 2010 Dec 21.   PubMed 21177381  


       
Yuan3 downloads
• Download Yuan3 project data set     one row per animal, one column per trait
• Download Yuan3 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Rong Yuan       The Jackson Laboratory Bar Harbor, ME
Ron Korstanje       The Jackson Laboratory Bar Harbor, ME
With: Tsaih SW, Schultz D, Godfrey D
ContactRong Yuan     rong.yuan@jax.org     Lab web site
AffiliationJAX Nathan Shock Aging Center
AcknowledgementsFunding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type Phenotype strain survey data set
MPD identifiersYuan3     MPD:244
Data changelog 3 updates/corrections.       Initial release date: 08/2008.
Formatted citation
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Summary of procedures that were conducted
• metabolic panel Clinical blood chemistry. Aging study, 6mo, 12mo, 18mo.
• lipid profile Cholesterol (HDL). Aging study, 6mo, 12mo, 18mo. 4h fast, plasma.
Mice: inbred   32 strains   ♀♂   age 6, 12, 18 mo   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Yuan3 24401 metabolic panel (none) alanine transaminase (plasma ALT)   [IU/L]     6mo    12mo    18mo inbred 29 both None N=6
    Yuan3 24406 metabolic panel (none) lipase (plasma LIP)   [U/L]     6mo    12mo    18mo inbred 29 both None N=7
    Yuan3 24411 metabolic panel (none) alkaline phosphatase (serum ALP)   [IU/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24416 metabolic panel (none) calcium (serum Ca)   [mg/dL]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24421 metabolic panel (none) chloride (serum Cl)   [mmol/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24426 metabolic panel (none) iron (serum Fe)   [mmol/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24431 metabolic panel (none) magnesium (serum Mg)   [mg/dL]     6mo    12mo    18mo inbred 28 both None N=6
    Yuan3 24436 metabolic panel (none) phosphorus (serum P)   [mg/dL]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24441 metabolic panel (none) potassium (serum K)   [mmol/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24446 metabolic panel (none) sodium (serum Na)   [mmol/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24451 metabolic panel (none) albumin (plasma Alb)   [g/dL]     6mo    12mo    18mo inbred 29 both None N=7
    Yuan3 24456 metabolic panel (none) total protein (plasma TP)   [g/dL]     6mo    12mo    18mo inbred 29 both None N=7
    Yuan3 24461 metabolic panel (none) dissolved-ionized carbon dioxide (CO2)   [mmol/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24466 metabolic panel (none) bilirubin (serum TBIL)   [µmol/L]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24471 lipid profile (none) HDL cholesterol (plasma HDL)   [mg/dL]     6mo    12mo    18mo inbred 29 both None N=7
    Yuan3 24476 metabolic panel (none) thyroxine (serum T4)   [µg/dL]     6mo    12mo    18mo inbred 28 both None N=7
    Yuan3 24481 metabolic panel (none) blood urea nitrogen (plasma BUN)   [mg/dL]     6mo    12mo    18mo inbred 29 both None N=6
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