Yuan3: Aging study: Blood chemistry for 32 inbred strains of mice (2008)

Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R. Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics. 2011 Mar 16;43(5):265-70. Epub 2010 Dec 21.   PubMed 21177381  

Yuan3 downloads
• Download Yuan3 project data set     animal data, as uploaded
• Download Yuan3 animal data matrix     with factor-related expansion applied as necessary
• Download Yuan3 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to Yuan3 measures:
  MA:0002501   plasma
  MA:0002502   serum
  MP:0000184   abnormal circulating HDL cholesterol level
  MP:0000199   abnormal circulating serum albumin level
  MP:0000202   abnormal circulating alkaline phosphatase level
  MP:0001562   abnormal circulating calcium level
  MP:0001565   abnormal circulating phosphate level
  MP:0001569   abnormal circulating bilirubin level
  MP:0001573   abnormal circulating alanine transaminase level
  MP:0001771   abnormal circulating magnesium level
  MP:0001776   abnormal circulating sodium level
  MP:0002668   abnormal circulating potassium level
  MP:0003018   abnormal circulating chloride level
  MP:0003860   abnormal carbon dioxide level
  MP:0004152   abnormal circulating iron level
  MP:0005265   abnormal blood urea nitrogen level
  MP:0005475   abnormal circulating thyroxine level
  MP:0011577   abnormal lipoprotein lipase activity
  MP:0011888   abnormal circulating total protein level
  VT:0000184   blood HDL cholesterol amount
  VT:0000199   blood albumin amount
  VT:0000202   blood alkaline phosphatase amount
  VT:0001562   blood calcium amount
  VT:0001565   blood phosphate amount
  VT:0001569   blood bilirubin amount
  VT:0001573   blood alanine transaminase amount
  VT:0001771   blood magnesium amount
  VT:0001776   blood sodium amount
  VT:0002329   blood gas amount
  VT:0002668   blood potassium amount
  VT:0003018   blood chloride amount
  VT:0004152   blood iron amount
  VT:0005265   blood urea nitrogen amount
  VT:0005475   blood thyroxine amount
  VT:0005567   blood total protein amount
  VT:0010478   blood lipase amount

Investigators Rong Yuan       The Jackson Laboratory,  Bar Harbor, ME
Ron Korstanje       The Jackson Laboratory,  Bar Harbor, ME
Participants Tsaih SW, Schultz D, Godfrey D
ContactRong Yuan     rong.yuan@jax.org     Lab web site
Affiliated CenterJAX Nathan Shock Aging Center
AcknowledgementsFunding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type Phenotype strain survey data set
MPD identifiersYuan3     MPD:244
Data changelog 3 updates/corrections.       Initial release date: 08/2008.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Procedures conducted:
• metabolic panel  Clinical blood chemistry. Aging study, 6mo, 12mo, 18mo.
• lipid profile  Cholesterol (HDL). Aging study, 6mo, 12mo, 18mo. 4h fast, plasma.

Mice: inbred   32 strains   ♀♂   age 26, 52, 78 wks   1 experimental group